Abstract:
:Aloe barbadensis polysaccharide was partially digested with cellulase and further purified by dialysis, stepwise ethanol precipitation, and size exclusion chromatography. Crude modified Aloe polysaccharide (MAP) activated macrophage cells and stimulated fibroblast growth. Under the same conditions, native Aloe barbadensis gel had no effect on macrophage activation. MAP prevented ultraviolet B (UVB) irradiation-induced immune suppression as determined by contact hypersensitivity (CHS) response in C3H/HeN mice. This in vivo activity was correlated with the activity of MAP to inhibit UVB irradiation-induced tumor necrosis factor alpha (TNF-alpha) release from human epidermoid carcinoma cells (KB cells). MAP with an average molecular weight of 80,000 Dalton (Da) contained mannose, galactose, and glucose in a ratio of 40:1.4:1.0. MAP was likely a linear, highly acetylated molecule.
journal_name
Planta Medjournal_title
Planta medicaauthors
Qiu Z,Jones K,Wylie M,Jia Q,Orndorff Sdoi
10.1055/s-2000-11125subject
Has Abstractpub_date
2000-03-01 00:00:00pages
152-6issue
2eissn
0032-0943issn
1439-0221journal_volume
66pub_type
杂志文章相关文献
PLANTA MEDICA文献大全abstract::An arabinogalactan-protein (AGP) from suspension culture medium of Malva sylvestris was isolated by precipitation with beta-glucosyl Yariv reagent, followed by gel-permeation chromatography. It revealed characteristic features of AGPs: a high amount of polysaccharide with a ratio of galactose to arabinose of 1.9 : 1, ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2002-23127
更新日期:2002-03-01 00:00:00
abstract::Five compounds representative of major structural classes of lichen polyketides, VIZ. (+)-usnic (1), salazinic (2), vulpinic (3), gyrophoric (4), and evernic acids (5), were investigated for their ability to affect cell proliferation or wound healing, two functional targets of relevance for research on cancer or tissu...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0029-1185329
更新日期:2009-05-01 00:00:00
abstract::Teak ( Tectona grandis L.f., Verbenaceae) sawdust extract inhibited the growth of Aspergillus niger. Centrifugal partition chromatography was used to isolate the active compounds. By (1)H-NMR the active compounds were identified as deoxylapachol and tectoquinone. Two A. niger transgenic strains which show induction of...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-946676
更新日期:2006-08-01 00:00:00
abstract::The essential oil composition of three Zingiberaceae widely used as medicinal aromatic plants from S. Tomé and Príncipe: Aframomum danielli (Hook. f.) K. Schum., Curcuma longa L. and Zingiber officinale Rosc. was studied. Two samples of the essential oils from fruit of A. danielli and from rhizomes of the other two sp...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2001-16494
更新日期:2001-08-01 00:00:00
abstract::Shoot-tips from several genotypes of the cardenolide-producing perennial shrub Digitalis obscura L. were successfully cryopreserved using the encapsulation-dehydration technique. Precultivation on MS medium containing 0.5 M sucrose, followed by 2.5 h dehydration (final weight 30 %) induced shoot regrowth in 42 % of cr...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2001-18861
更新日期:2001-12-01 00:00:00
abstract::Three new compounds, namely, (+)-dihydrodehydrodiconiferyl alcohol 4- O- beta-(6''- O-galloyl)-glucopyranoside ( 1), 4,4'- O-dimethylellagic acid 3-(2''- O-acetyl)- alpha-rhamnopyranoside ( 2), and ethyl O- beta-(6'-galloyl)-glucopyranoside ( 3), together with eleven known ones, were isolated from the stem bark of Tre...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2008-1034361
更新日期:2008-03-01 00:00:00
abstract::This in vitro study aimed to determine the effects of a Panax ginseng extract on aristolochic acid-mediated toxicity in HK-2 cells. A methanolic extract of ginseng (50 µg/mL) was able to reduce cell survival after treatment with 50 µM aristolochic acid for 24, 48, and 72 h, as evidenced by a resazurin reduction assay....
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0035-1545839
更新日期:2015-03-01 00:00:00
abstract::Herpes simplex virus infections persist throughout the lifetime of the host and affect more than 80 % of the humans worldwide. The intensive use of available therapeutic drugs has led to undesirable effects, such as drug-resistant strains, prompting the search for new antiherpetic agents. Although diverse bioactivitie...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0042-117774
更新日期:2017-04-01 00:00:00
abstract::Guinea pigs were sensitized with trinitrophenylated liver macromolecular protein fraction (TNP-LP1) prepared by using sodium trinitrobenzenesulfonate of strong immunogenicity as the hapten and LP1 as the carrier protein. The administration of trinitrophenylated hepatocytes and lipopolysaccharide to these TNP-LP1-sensi...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-960006
更新日期:1991-02-01 00:00:00
abstract::Two new beta-carboline alkaloids, hedyocapitelline and hedyocapitine, were isolated from Hedyotis capitellata var. mollis (Rubiaceae). Their structures were elucidated by spectroscopic data (1)H- and (13)C-NMR, MS, IR, UV). ...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2006-960861
更新日期:1999-12-01 00:00:00
abstract::We report the effects of aqueous extracts of the microalgae Dunaliella tertiolecta Butcher (Chlorophyceae) and Phaeodactylum tricornutum Bohlin (Bacillariophyceae) on oxotremorin-induced cholinergic symptoms, amphetamine-induced hypermotility, pentylenetetrazole-induced convulsions, and Rota-rod test performance. Both...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-960914
更新日期:1990-04-01 00:00:00
abstract::Since the beginning of this century, Goji berries and juice are being sold as health food products in western countries and praised in advertisements and in the media for well-being and as an anti-aging remedy. The popularity of Goji products has rapidly grown over the last years thanks to efficient marketing strategi...
journal_title:Planta medica
pub_type: 杂志文章,评审
doi:10.1055/s-0029-1186218
更新日期:2010-01-01 00:00:00
abstract::Ligusticum canbyi (J.M. Coult & Rose) is a medicinal understory forest species used in traditional rituals and ceremonies for spiritual enlightenment and improved mental health. Very little is known about the phytochemical complexity or diversity of L. canbyi tissues or extracts. The current study was undertaken to de...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0033-1350618
更新日期:2013-09-01 00:00:00
abstract::The gamma-amino butyric acid (GABA) type A (GABA(A)) receptor represents a crucial target for clinical agents in the treatment of anxiety and insomnia. Using the two-microelectrode voltage clamp technique on recombinant α₁β₂γ(2S) GABA (A) receptors, effusol (1) and dehydroeffusol (2) were isolated in a bioactivity-gui...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0031-1298174
更新日期:2012-03-01 00:00:00
abstract::Catharanthus roseus cell suspension cultures were employed for the biotransformation of 2alpha,5alpha,10beta,14beta-tetraacetoxy-4(20),11-taxadiene ( 1), and four metabolites were obtained. Based on their physical and chemical data, the structures of the four metabolites were respectively elucidated as 10beta-hydroxy-...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2002-36340
更新日期:2002-12-01 00:00:00
abstract::The configurations of the component amino acids in ginseng tetrapeptide 1 isolated from Panax ginseng were determined by HPLC with an optical resolution column and the structure of 1 was established to be H-L-Val-gamma-D-Glu-D-Arg- Gly-OH. Synthesis of the ginseng tetrapeptide, 1, and of the configuration and conjugat...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957830
更新日期:1996-04-01 00:00:00
abstract::A micellar electrokinetic capillary chromatography (MEKC) method for the determination of xanthyletin and xanthoxyletin in the roots bark of three Citrus plants was developed for the first time. The electrophoresis buffer was 10 mmol/L sodium borate containing 50 mmol/L sodium dodecyl sulfate, 20% (v/v) acetonitrile a...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2003-39697
更新日期:2003-05-01 00:00:00
abstract::Three new guaiane-type sesquiterpene lactones (1-3), together with nine related sesquiterpenes (4-12), were isolated from the whole extract of Ixeris dentata (Asteraceae). The chemical structures of isolates 1-12 were established by spectroscopic analyses as 3 β,8 β-dihydroxy-guaia-10(14)-en-1 α,4 α,5 α,6 β,7 α,11 βH-...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0030-1250369
更新日期:2011-03-01 00:00:00
abstract::The investigation of the roots and aerial parts of EUPATORIUM CANNABIUM afforded, in addition to the sesquiterpene lactones eupatolide, eupatoriopicrin, and eucannabinolide isolated previously, eight further lactones, three of which are new. Furthermore, in addition to known compounds, a new clerodane derivative and t...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-962665
更新日期:1987-04-01 00:00:00
abstract::Phytochemical studies on Galanthus species resulted in the isolation of three new compounds: 3,3'-O-(3',3''-dihydroxybutanoyl)hamayne and 11,3'-O-(3',3''-dihydroxybutanoyl)hamayne from G. nivalis and 2-O-(3'-hydroxybutanoyl)lycorine from G. elwesii. Additionally, 3,11-O-(3',3''-dihydroxybutanoyl)hamayne, 3,11,3'-O-(3'...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-0029-1185575
更新日期:2009-10-01 00:00:00
abstract::A simple and efficient method for the separation of the three phenolic diketones, curcumin 1, demethoxycurcumin 2, and bis-demethoxycurcumin 3, isolated from the rhizomes of Curcuma longa has been developed. The method is of general applicability for the separation of compounds containing acidic and chelating groups a...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2000-8533
更新日期:2000-05-01 00:00:00
abstract::This review describes the current status of the development of techniques combining liquid chromatography and nuclear magnetic resonance and their use in the context of natural products. HPLC-NMR methods have a rapidly growing impact on natural products research by enabling structure determination of natural products ...
journal_title:Planta medica
pub_type: 杂志文章,评审
doi:10.1055/s-2005-871298
更新日期:2005-08-01 00:00:00
abstract::We have identified kamebakaurin as an inhibitor of NF-KB and elucidated its molecular mechanism as a specific inhibitor in the DNA-binding activity of the p50 subunit of NF-KB. Here, we describe its anti-inflammatory activity in in vitro and in vivo models. Kamebakaurin dose-dependently inhibited not only the expressi...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2004-827152
更新日期:2004-06-01 00:00:00
abstract::A methanolic extract of Commelina communis showed potent inhibitory activity against alpha-glucosidase. One pyrrolidine alkaloid, 2,5-dihydroxymethyl-3,4-dihydroxypyrrolidine (DMDP, 1) and four piperidine alkaloids, 1-deoxymannojirimycin (2), 1-deoxynojirimycin (3), alpha-homonojirimycin (4) and 7-O-beta-D-glucopyrano...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2006-960803
更新日期:1999-06-01 00:00:00
abstract::A new tetrahydrofuran lignan, named henricine ( 1), was isolated from the stems of SCHISANDRA HENRYI. High resolution COSY spectrum was used in the structural elucidation. ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-969265
更新日期:1986-12-01 00:00:00
abstract::Our investigations into the stability of tincture preparations of milk thistle fruit [ Silybum marianum L. Gaertn. (Asteraceae)] have led to the characterization of a new flavonolignan 4-(4-hydroxy-3-methoxyphenyl)-7-[(2 R,3 R)-3,5,7-trihydroxy-4-oxochroman-2-yl]-1-oxo-1,3,3a,4,5,7a-hexahydro-2-benzofuran-5-carboxylic...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-981595
更新日期:2007-09-01 00:00:00
abstract::Three new sauchinone analogues, sauchinones B-D (1-3), together with sauchinone (4), were isolated from the aerial part of Saururus chinensis. Structures of the new compounds were determined by extensive spectroscopic data as well as X-ray analysis. Compounds 3 and 4 inhibited nitric oxide production in lipopolysaccha...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0033-1351053
更新日期:2013-12-01 00:00:00
abstract::A gas-chromatographical method is described on which seven pyrrolizidine alkaloids (Fuchsisenecionine, Senecionine, Senecivernine, Senkirkine, Retrorsine, O (7)-Angelylheliotridine and Heliotrine) are determinated in a qualitative way and their ratio of concentration in Senecio fuchsii, vernalis, inaequidens and ovire...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-971688
更新日期:1981-02-01 00:00:00
abstract::Ten new polyhydroxyolean-12-ene pentacyclic triterpenoidal saponins, named rogchaponins 1-10, were isolated from the methanolic extract of the roots of Camellia sinensis by a series of chromatographic methods (silica gel flash column and C18 MPLC followed by C18 HPLC). Their structures were established by 1D and 2D-NM...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0031-1280024
更新日期:2011-12-01 00:00:00
abstract::The fruits of OSTEOPHLOEUM PLATYSPERMUM (Myristicaceae) contain sitosterol, eperu-8(20),13-dien-3alpha,15-diol, glyceryl laurodimyristate, glyceryl 1,3-lauromyristate and five neolignans: dihydroguaiaretic acid, hydroxyotobain, hydroxyoxootobain, guaiacin and otobaphenol. ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-969620
更新日期:1984-02-01 00:00:00