GABA(A) receptor modulators from the Chinese herbal drug Junci Medulla--the pith of Juncus effusus.

abstract：:In our previous study, we reported the interesting in vitro antiplasmodial activity of some Rwandan plant extracts. This gave rise to the need for these extracts to also be evaluated in vivo and to identify the compounds responsible for their antiplasmodial activity. The aim of our study was, on the one hand, to evalu...

journal_title：Planta medica

authors： Muganga R,Angenot L,Tits M,Frédérich M

更新日期：2014-04-01 00:00:00

abstract：:DNA technology provides a powerful tool to complement chemical analyses for authentication of Chinese medicinal plants and to ensure that herbal materials are not contaminated with ineffective or potentially harmful substitutes or adulterants. In the last two decades molecular biotechnology has provided sophisticated ...

journal_title：Planta medica

authors： Heubl G

更新日期：2010-12-01 00:00:00

abstract：:From the defatted seeds of Cassia marginata fam (Caesalpinaceae) two new anthraquinone glycosides have been isolated and characterised as physcion-8-O-alpha-L-xylopyranoside and emodin-8-O-alpha-L-arabinopyranoside. ...

journal_title：Planta medica

authors： Duggal JK,Misra K

更新日期：1982-05-01 00:00:00

abstract：:A sensitive and rapid liquid chromatography-mass spectrometric method for the determination of ophiopogonin D in rat plasma was developed and validated. Chromatographic separation was performed on a C (18) column using a step gradient program with the mobile phase of 0.5 mmol/L ammonium chloride solution and acetonitr...

journal_title：Planta medica

authors： Xia CH,Sun JG,Hao HP,Wang GJ,Yan B,Gu SH,Zheng CN,Shang LL,Roberts MS

更新日期：2008-12-01 00:00:00

abstract：:Effects of passage of subculture and several culture conditions, nutritional, hormonal and light conditions on 3,4-dihydroxyphenylalanine (DOPA) content were examined in callus of STIZOLOBIUM HASSJOO P IPER and T RACY. The favourable conditions for DOPA accumulation were found to be suboptimal conditions for growth, i...

journal_title：Planta medica

authors： Obata-Sasamoto H,Komamine A

更新日期：1983-10-01 00:00:00

abstract：:Hepatocellular carcinoma is one of the leading causes of malignancy-related death in China. Its therapy in clinics is a big challenge. Ginsenoside Rh2 is one of the most notable cancer-preventing components from red ginseng and it has been reported that ginsenoside Rh2 exhibited potent cytotoxicity against human hepat...

journal_title：Planta medica

authors： Lv Q,Rong N,Liu LJ,Xu XL,Liu JT,Jin FX,Wang CM

更新日期：2016-05-01 00:00:00

abstract：:Extracts of Viscum album L. produced by a specific homogenization procedure contain viscotoxins (VT) and liposome-like membrane vesicles, formed from cellular membranes. Interactions between these membrane structures and viscotoxins are characterized in this work. Binding properties of viscotoxins with mistletoe extra...

journal_title：Planta medica

authors： Winkler K,Jäger S,Leneweit G,Schubert R

更新日期：2008-02-01 00:00:00

abstract：:Panaxytriol, a polyacetylenic compound, isolated from red ginseng (Panax ginseng C.A. Meyer), was studied to determine its effects on the growth and cell cycle of tumor cell lines. The compound showed both significant cytotoxicity and inhibition of DNA syntheses in various tumor cells tested. For P388D1, a mouse lymph...

journal_title：Planta medica

authors： Kim JY,Lee KW,Kim SH,Wee JJ,Kim YS,Lee HJ

更新日期：2002-02-01 00:00:00

abstract：:The dichloromethane-soluble fraction of the methanol extract of the stem bark of Millettia versicolor Welw. (Leguminosae) has been shown to possess anti-inflammatory activity. The chromatographic fractionation and subsequent analysis of the spectroscopic data of this extract led to the isolation and identification of ...

journal_title：Planta medica

authors： Fotsing MT,Yankep E,Njamen D,Fomum ZT,Nyasse B,Bodo B,Recio MC,Giner RM,Ríos JL

更新日期：2003-08-01 00:00:00

abstract：:The inhibition of aflatoxin B1 (AFB1) metabolism by a water extract of the root of Scutellaria baicalensis and its flavonoids was examined in liver microsomes. AFB1 is known to be metabolized to aflatoxin M1 (AFM1), aflatoxin Q1 (AFQ1), and AFB1-8,9-epoxide (AFBO). The water extract potently inhibited the production o...

journal_title：Planta medica

authors： Kim BR,Kim DH,Park R,Kwon KB,Ryu DG,Kim YC,Kim NY,Jeong S,Kang BK,Kim KS

更新日期：2001-07-01 00:00:00

abstract：:Five new triterpenoid saponins (1-5) and four known triterpenoid saponins, ginsenoside Re5 (6), majonoside R1 (7), 24(R)-majonoside R1 (8), and ginsenoside Rf (9), were isolated from the rhizomes of Panacis majoris. The structures of new compounds were elucidated as (20S,24S,25R*)-6-O-[β-D-glucopyranosyl-(1 → 2)-β-D-g...

journal_title：Planta medica

authors： Li M,Liu F,Jin YR,Wang XZ,Wu Q,Liu Y,Li XW

更新日期：2017-02-01 00:00:00

abstract：:The inhibitory action of the major constituent of Sebastiania schottiana (Euphorbiaceae), 2-hydroxy-4,6-dimethoxyacetophenone (xanthoxyline) on contractions induced by agonists and electrical stimulation of smooth and cardiac muscle preparations was analysed. Xanthoxyline (30 to 300 microM) inhibited contractions of t...

journal_title：Planta medica

authors： Calixto JB,Miguel OG,Yunes RA,Rae GA

更新日期：1990-02-01 00:00:00

abstract：:Two new secodammarane triterpenoid saponins were isolated from the leaves of Cyclocarya paliurus. Based on chemical and spectral analysis they were assigned as (20S)-20-hydroxy-24-O-alpha-L-arabino-pyranosyl-3,4- secodammar-4(28),11,25-trien-3-oic acid, named cyclocarioside II and 25-hydroxy-(20S,24R)-epoxy-12R-O-beta...

journal_title：Planta medica

authors： Shu RG,Xu CR,Li LN,Yu ZL

更新日期：1995-12-01 00:00:00

abstract：:Ten clones of dark-leaved willows ( Salix myrsinifolia Salisb.) were grown for two years on two different sites, Luikonlahti and Punkaharju, using various combinations of soil cultivation, fertilization and mulch treatments, with the objective of comparing the effect of different cultivation methods on the growth and ...

journal_title：Planta medica

authors： Heiska S,Rousi M,Turtola S,Meier B,Tirkkonen V,Julkunen-Tiitto R

更新日期：2005-12-01 00:00:00

abstract：:Plumbagin, an active principle from Plumbaginaceous plants, produced a triphasic inotropic response (first positive, second negative, and third positive phases) in guinea-pig papillary muscle. The inotropic potency of plumbagin at the first positive phase was pD2 6.40, and the methylation of 5-hydroxy group of plumbag...

journal_title：Planta medica

authors： Itoigawa M,Takeya K,Furukawa H

更新日期：1991-08-01 00:00:00

abstract：:The purpose of this study was to investigate dermal pharmacokinetics of terpinen-4-ol in rats following topical administration of plai oil derived from the rhizomes of Zingiber cassumunar Roxb. Unbound terpinen-4-ol concentrations in dermal tissue were measured by microdialysis. The dermal pharmacokinetic study of ter...

journal_title：Planta medica

authors： Chooluck K,Singh RP,Sathirakul K,Derendorf H

更新日期：2012-11-01 00:00:00

abstract：:The aerial parts of DODONAEA VISCOSA afforded a new diterpenoid, dodonic acid, the structure and stereochemistry of which have been established by chemical and spectroscopic means. ...

journal_title：Planta medica

authors： Sachdev K,Kulshreshtha DK

更新日期：1984-10-01 00:00:00

abstract：:Olive mill waste water is the major byproduct of the olive oil industry containing a range of compounds related to Olea europaea and olive oil constituents. Olive mill waste water comprises an important environmental problem in olive oil producing countries, but it is also a valuable material for the isolation of high...

journal_title：Planta medica

authors： Vougogiannopoulou K,Angelopoulou MT,Pratsinis H,Grougnet R,Halabalaki M,Kletsas D,Deguin B,Skaltsounis LA

更新日期：2015-08-01 00:00:00

abstract：:The present study is aimed at evaluating the effects of luteolin on the scratching behavior associated with an allergic cutaneous reaction in mice. Elicitation of passive cutaneous anaphylaxis, and intradermal injections of compound 48/80, histamine or serotonin induced scratching behavior in ICR mice. Models of irrit...

journal_title：Planta medica

authors： Baolin L,Weiwei W,Ning T

更新日期：2005-05-01 00:00:00

abstract：:Ocimum basilicum L. is an aromatic herb used in Brazil to treat illnesses such as respiratory and rheumatic problems, vomiting, and pain. In the present study, the chemical composition, acute toxicity, and antinociceptive effects of the essential oil (EO) of the cultivar "Maria Bonita" obtained from O. basilicum L. PI...

journal_title：Planta medica

authors： Venâncio AM,Onofre AS,Lira AF,Alves PB,Blank AF,Antoniolli AR,Marchioro M,Estevam Cdos S,de Araujo BS

更新日期：2011-05-01 00:00:00

abstract：:A total of 37 commercial samples of Ginseng Radix, the origins of which belonged to Panax ginseng C. A. Meyer, P. quinquefolia Linn. (American ginseng), and P. notoginseng Burkill (sanchi-ginseng), respectively, were collected from the Taiwan herbal markets. The contents of nine ginsenosides, Rb(1), Rb(2), Rc, Rd, Re,...

journal_title：Planta medica

authors： Chuang WC,Wu HK,Sheu SJ,Chiou SH,Chang HC,Chen YP

更新日期：1995-10-01 00:00:00

abstract：:From the essential oil of Commiphora guidotti seven sesquiterpene hydrocarbons and a furanosesquiterpenoid, furanodiene, were isolated. ...

journal_title：Planta medica

authors： Craveiro A,Corsano S,Proietti G,Strappaghetti G

更新日期：1983-06-01 00:00:00

abstract：:The flowers of ARNICA MOLLIS afforded, in addition to baileyin ( 1A), baileyin acetate ( 1B), xanthalongin ( 3), and 2-deacetoxy-11alpha,13-dihydroxanthuminol ( 6), the new 1,5- CIS-guaianolides arnimollin acetate ( 2A) and arnimollin tiglinate ( 2A) and the new xanthanolides 11beta3,13-dihydroxanthalongin ( 4) and 11...

journal_title：Planta medica

authors： Marcinek-Hüpen-Bestendonk C,Willuhn G,Steigel A,Wendisch D,Middelhauve B,Wiebcke M,Mootz D

更新日期：1990-02-01 00:00:00

abstract：:A new isoprenylated xanthone, cudrafrutixanthone A, was isolated from the roots of Cudrania fruticosa, together with 18 known compounds. Their structures were elucidated by spectroscopic methods. Most isoprenylated xanthones exhibited cytotoxicity against HCT-116, SMMC-7721, SGC-7901, and BGC-823 cell lines with IC (5...

journal_title：Planta medica

authors： Wang YH,Hou AJ,Zhu GF,Chen DF,Sun HD

更新日期：2005-03-01 00:00:00

abstract：:The antiviral activities of two saponins, soyasaponin I and II, isolated from soybean (Glycine max Merrill) were studied in vitro against herpes simplex virus type 1 (HSV-1). Soyasaponin II was more potent than soyasaponin I as shown by reduction of HSV-1 production. Soyasaponin II was also found to inhibit the replic...

journal_title：Planta medica

authors： Hayashi K,Hayashi H,Hiraoka N,Ikeshiro Y

更新日期：1997-04-01 00:00:00

abstract：:Three new steroidal saponins were isolated from the fruits of Tribulus terrestris, and their structures were elucidated as (25R,S)-5 alpha-spirostane-12-one-3 beta-ol-3-O-beta-xylopyranosyl(1-->2)- [beta-xylopyranosyl(1-->3)]-beta-glucopyranosyl(1-->4)-[alpha-rhamno- pyranosyl(1-->2)]-beta-galactopyranoside; 26-O-beta...

journal_title：Planta medica

authors： Cai L,Wu Y,Zhang J,Pei F,Xu Y,Xie S,Xu D

更新日期：2001-03-01 00:00:00

abstract：:Amyloid-β, one of the hallmarks of Alzheimer's disease, is toxic to neurons and causes cell death in the brain. Oxidative stress is known to play an important role in Alzheimer's disease, and there is strong evidence linking oxidative stress to amyloid-β. The herbal plant "Tiew kon" (Cratoxylum formosum ssp. pruniflor...

journal_title：Planta medica

authors： Keowkase R,Weerapreeyakul N

更新日期：2016-04-01 00:00:00

abstract：:Plectranthus barbatus Andr. is one of the most important species of the genus Plectranthus L' Herit. (Lamiaceae), with a wide variety of traditional medicinal uses in Hindu and Ayurvedic traditional medicine as well as in the folk medicine of Brazil, tropical Africa and China. The plant has therefore been an attractiv...

journal_title：Planta medica

authors： Alasbahi RH,Melzig MF

更新日期：2010-05-01 00:00:00

abstract：:Protodioscin (NSC-698 796) is a furostanol saponin isolated from the rhizome of Dioscorea collettii var. hypoglauca (Dioscoreaceae), a Chinese herbal remedy for the treatment of cervical carcinoma, carcinoma of urinary bladder and renal tumor for centuries. To systematically evaluate its potential anticancer activity,...

journal_title：Planta medica

authors： Hu K,Yao X

更新日期：2002-04-01 00:00:00

abstract：:(1)H- and (13)C-NMR spectral data are presented for six p-terphenylquinone derivatives (and for two monosubstituted quinones 1 and 2, used as model compounds) and for 9,10-phenanthraquinone and retenequinone. The chemical shifts were confirmed through correlation spectroscopy and NOE measurements. ...

journal_title：Planta medica

authors： Jokela R,Lounasmaa M

更新日期：1997-08-01 00:00:00