Chemical and Biological Investigation of Olive Mill Waste Water - OMWW Secoiridoid Lactones.

Abstract:

:Olive mill waste water is the major byproduct of the olive oil industry containing a range of compounds related to Olea europaea and olive oil constituents. Olive mill waste water comprises an important environmental problem in olive oil producing countries, but it is also a valuable material for the isolation of high added value compounds. In this study, an attempt to investigate the secoiridoid content of olive mill waste water is described with the aid of ultrahigh-performance liquid chromatography-electrospray ionization (±)-high-resolution mass spectrometry and centrifugal partition chromatography methods. In total, seven secoiridoid lactones were isolated, four of which are new natural products. This is the first time that a conjugate of hydroxytyrosol and a secoiridoid lactone has been isolated from olive mill waste water and structurally characterized. Furthermore, the range of isolated compounds allowed for the proposal of a hypothesis for the biotransformation of olive secoiridoids during the production of olive mill waste water. Finally, the ability of the representative compounds to reduce the intracellular reactive oxygen species was assessed with the dichlorofluorescein assay in conjunction with the known antioxidant agent hydroxytyrosol.

journal_name

Planta Med

journal_title

Planta medica

authors

Vougogiannopoulou K,Angelopoulou MT,Pratsinis H,Grougnet R,Halabalaki M,Kletsas D,Deguin B,Skaltsounis LA

doi

10.1055/s-0035-1546243

subject

Has Abstract

pub_date

2015-08-01 00:00:00

pages

1205-12

issue

12-13

eissn

0032-0943

issn

1439-0221

journal_volume

81

pub_type

杂志文章
  • Fast and Green - CO2 Based Extraction, Isolation, and Quantification of Phenolic Styrax Constituents.

    abstract::In this study the first supercritical fluid based protocol for the extraction, analysis, and isolation of six polar compounds, i.e., o-vanillin (1), styracin (2), vanillin (3), trans-cinnamic acid (4), vanillic acid (5), and shikimic acid (6), was developed. First, eight styrax resin products (R1-R8) obtained from var...

    journal_title:Planta medica

    pub_type: 杂志文章

    doi:10.1055/s-0043-105499

    authors: Scheuba J,Wronski VK,Rollinger JM,Grienke U

    更新日期:2017-08-01 00:00:00

  • Constituents of essential oil of Commiphora guidotti.

    abstract::From the essential oil of Commiphora guidotti seven sesquiterpene hydrocarbons and a furanosesquiterpenoid, furanodiene, were isolated. ...

    journal_title:Planta medica

    pub_type: 杂志文章

    doi:10.1055/s-2007-969896

    authors: Craveiro A,Corsano S,Proietti G,Strappaghetti G

    更新日期:1983-06-01 00:00:00

  • Influence of acetonylgeraniin, a hydrolyzable tannin from Euphoria longana, on orthostatic hypotension in a rat model.

    abstract::Acetonylgeraniin, an active principle isolated from the seeds of Euphoria longana Lam. (Sapindaceae), reversed the fall in arterial blood pressure in conscious hypertensive rats (SHRs) with orthostatic hypotension induced by injection of hexamethonium into animals subjected to 90 degrees head-up tilts for 60 seconds. ...

    journal_title:Planta medica

    pub_type: 杂志文章

    doi:10.1055/s-2006-959487

    authors: Hsu FL,Lu FH,Cheng JT

    更新日期:1994-08-01 00:00:00

  • Anti-hepatitic activity of ginesenoside ro1.

    abstract::Ginsenoside Ro, an oleanane-type saponin has been screened for activity in experimental models of acute and chronic hepatitis. Ginsenoside Ro (50 and 200 mg/kg, P.O.) inhibited the increase of serum glutamic oxaloacetic transaminase (s-GOT) and serum glutamic pyruvic transaminase (s-GPT) levels in D-galactosamine (Gal...

    journal_title:Planta medica

    pub_type: 杂志文章

    doi:10.1055/s-2006-960198

    authors: Matsuda H,Samukawa K,Kubo M

    更新日期:1991-12-01 00:00:00

  • Stimulation of Indole Alkaloid Production in Cell Suspension Cultures of Catharanthus roseus by Abscisic Acid.

    abstract::When added to suspension cultures of CATHARANTHUS ROSEUS, abscisic acid (ABA) stimulated intracellular accumulation of the indole alkaloids catharanthine and ajmalicine in both flask and 30 litre fermenter-scale systems. The response varied, and depended upon the cell line, the concentration and source of the ABA, and...

    journal_title:Planta medica

    pub_type: 杂志文章

    doi:10.1055/s-2006-962775

    authors: Smith JI,Smart NJ,Kurz WG,Misawa M

    更新日期:1987-10-01 00:00:00

  • Detection of Ganoderic Acid A in Ganoderma lingzhi by an Indirect Competitive Enzyme-Linked Immunosorbent Assay.

    abstract::Ganoderma is a genus of medicinal mushroom traditionally used for treating various diseases. Ganoderic acid A is one of the major bioactive Ganoderma triterpenoids isolated from Ganoderma species. Herein, we produced a highly specific monoclonal antibody against ganoderic acid A (MAb 12 A) and developed an indirect co...

    journal_title:Planta medica

    pub_type: 杂志文章

    doi:10.1055/s-0042-104202

    authors: Sakamoto S,Kohno T,Shimizu K,Tanaka H,Morimoto S

    更新日期:2016-05-01 00:00:00

  • Evaluation of immunomodulatory activity of an extract of andrographolides from Andographis paniculata.

    abstract::The immunomodulatory activity of HN-02, an extract containing a mixture of andrographolides (i.e., andrographolide [88 +/- 5 %] plus 14-deoxyandrographolide and 14-deoxy-11,12-didehydroandrographolide together [12 +/- 3 %]) in a pure powder form was evaluated at 1.0, 1.5, and 2.5 mg/kg on different in vivo and in vitr...

    journal_title:Planta medica

    pub_type: 杂志文章

    doi:10.1055/s-0029-1185398

    authors: Naik SR,Hule A

    更新日期:2009-06-01 00:00:00

  • Antinociception caused by the extract of Hedyosmum brasiliense and its active principle, the sesquiterpene lactone 13-hydroxy-8,9-dehydroshizukanolide.

    abstract::The hydroalcoholic extract (HE) obtained from stems and leaves of Hedyosmum brasiliense, given i.p., produced significant inhibition of acetic acid-induced abdominal constriction in mice, with a mean ID50 of 12.7 mg/kg. This effect installed rapidly (0.5 h) and lasted for up to 2 h. Given orally up to 1000 mg/kg, the ...

    journal_title:Planta medica

    pub_type: 杂志文章

    doi:10.1055/s-1999-14007

    authors: Trentin AP,Santos AR,Guedes A,Pizzolatti MG,Yunes RA,Calixto JB

    更新日期:1999-08-01 00:00:00

  • Two new derivatives of griseofulvin from the mangrove endophytic fungus Nigrospora sp. (strain No. 1403) from Kandelia candel (L.) Druce.

    abstract::Two new compounds, methyl 3-chloro-6-hydroxy-2-(4-hydroxy-2-methoxy-6-methylphenoxy)-4-methoxybenzoate (1) and (2 S,5' R,E)-7-hydroxy-4,6-dimethoxy-2-(1-methoxy-3-oxo-5-methylhex-1-enyl)-benzofuran-3(2H)-one (2), together with four known compounds, griseofulvin (3), dechlorogriseofulvin (4), bostrycin (5), and deoxybo...

    journal_title:Planta medica

    pub_type: 杂志文章

    doi:10.1055/s-0030-1271040

    authors: Xia X,Li Q,Li J,Shao C,Zhang J,Zhang Y,Liu X,Lin Y,Liu C,She Z

    更新日期:2011-10-01 00:00:00

  • A Review of the Toxicity of Compounds Found in Herbal Dietary Supplements.

    abstract::Use of herbal dietary supplements by the public is common and has been happening for centuries. In the United States, the Food and Drug Administration has a limited scope of regulation over marketed herbal dietary supplements, which may contain toxic botanical compounds that pose a public health risk. While the Food a...

    journal_title:Planta medica

    pub_type: 杂志文章,评审

    doi:10.1055/a-0605-3786

    authors: Hudson A,Lopez E,Almalki AJ,Roe AL,Calderón AI

    更新日期:2018-07-01 00:00:00

  • Inhibitory activity of soyasaponin II on virus replication in vitro.

    abstract::The antiviral activities of two saponins, soyasaponin I and II, isolated from soybean (Glycine max Merrill) were studied in vitro against herpes simplex virus type 1 (HSV-1). Soyasaponin II was more potent than soyasaponin I as shown by reduction of HSV-1 production. Soyasaponin II was also found to inhibit the replic...

    journal_title:Planta medica

    pub_type: 杂志文章

    doi:10.1055/s-2006-957622

    authors: Hayashi K,Hayashi H,Hiraoka N,Ikeshiro Y

    更新日期:1997-04-01 00:00:00

  • Further Triterpenoids of Musanga cecropioides: The Structure of Cecropic Acid.

    abstract::Six pentacyclic triterpenic acid methyl esters have been isolated from the methylated ethyl acetate extract of the trunk wood of MUSANGA CECROPIOIDES, as well as a triterpene saponin of the same group. One of them, cecropic acid methyl ester, is new. The structures of these compounds have been established from interpr...

    journal_title:Planta medica

    pub_type: 杂志文章

    doi:10.1055/s-2006-960959

    authors: Lontsi D,Sondengam BL,Ayafor JF,Tsoupras MG,Tabacchi R

    更新日期:1990-06-01 00:00:00

  • [New quinones in Rubia cordifolia L. Roots, III].

    abstract::From roots of Rubia cordifolia L. four anthraquinones are isolated: 1-hydroxy 2-methoxy anthraquinone; 1,4-dihydroxy 2-methyl 5-methoxy anthraquinone or 1,4-dihydroxy 2-methyl 8-methoxy anthraquinone; 1,3-dimethoxy 2-carboxy anthraquinone and rubiadin. ...

    journal_title:Planta medica

    pub_type: 杂志文章

    doi:10.1055/s-2007-971524

    authors: Dosseh C,Tessier AM,Delaveau P

    更新日期:1981-12-01 00:00:00

  • Cardioprotection and matrix metalloproteinase-9 regulation of salvianolic acids on myocardial infarction in rats.

    abstract::Acute myocardial infarction (AMI) remains the leading cause of mortality in the world. Early intervention using salvianolic acids (SA) can substantially improve clinical outcomes. However, in spite of the great achievements that have been made in elucidating the protective effects of SA on AMI, the effects of SA on th...

    journal_title:Planta medica

    pub_type: 杂志文章

    doi:10.1055/s-0029-1185669

    authors: Jiang B,Wu W,Li M,Xu L,Sun K,Yang M,Guan S,Liu X,Guo DA

    更新日期:2009-10-01 00:00:00

  • Phillyrin, a natural lignan, attenuates tumor necrosis factor α-mediated insulin resistance and lipolytic acceleration in 3T3-L1 adipocytes.

    abstract::In obese adipose tissue, tumor necrosis factor-α secreted from macrophages plays an important role in the adipocyte dysfunctions, including insulin resistance, lipolytic acceleration, and changes of adipokines, which promote the development of obesity-related complications. Phillyrin, an active ingredient found in man...

    journal_title:Planta medica

    pub_type: 杂志文章

    doi:10.1055/s-0034-1368614

    authors: Kong P,Zhang L,Guo Y,Lu Y,Lin D

    更新日期:2014-07-01 00:00:00

  • New Flavonoids from Boldoa purpurascens Cav.

    abstract::Phytochemical analysis of the leaves of BOLDOA PURPURASCENS Cav. led to isolation of four flavone glycosides, three of which are new compounds. Their structures have been determined by mass spectrometry and by 1 D and 2 D NMR analysis, i. e., 4',5-dihydroxy-6,7-methylenedioxyflavonol 3- O-alpha- L-rhamnopyranosyl-(1--...

    journal_title:Planta medica

    pub_type: 杂志文章

    doi:10.1055/s-2008-1081332

    authors: Mosquera DM,Kilonda A,Toppet S,Compernolle F,Dehaen W,François IE,Cammue BP,Apers S,Pieters L,Cuéllar AC

    更新日期:2008-10-01 00:00:00

  • MicroRNAs as New Bioactive Components in Medicinal Plants.

    abstract::Herbal medicine has been used to treat diseases for centuries; however, the biological active components and the mechanistic understanding of actions of plant-derived drugs are permanently discussed. MicroRNAs are a class of small, non-coding RNAs that play crucial roles as regulators of gene expression. In recent yea...

    journal_title:Planta medica

    pub_type: 杂志文章,评审

    doi:10.1055/s-0042-108450

    authors: Xie W,Weng A,Melzig MF

    更新日期:2016-08-01 00:00:00

  • Antifungal chromans inhibiting the mitochondrial respiratory chain of pea seeds and new xanthones from Calophyllum caledonicum.

    abstract::Two new xanthones, caledonixanthone M 1 and caloxanthone L 2, and one new acid, caledonic acid 6 were isolated from the hexane-soluble extract of the stem bark of Calophyllum caledonicum. In the course of this phytochemical study, seven other known compounds - calothwaitesixanthone, calozeyloxanthone, allanxanthone, i...

    journal_title:Planta medica

    pub_type: 杂志文章

    doi:10.1055/s-2003-818004

    authors: Hay AE,Guilet D,Morel C,Larcher G,Macherel D,Le Ray AM,Litaudon M,Richomme P

    更新日期:2003-12-01 00:00:00

  • Identification of an anti-inflammatory principle from the stem bark of Millettia versicolor.

    abstract::The dichloromethane-soluble fraction of the methanol extract of the stem bark of Millettia versicolor Welw. (Leguminosae) has been shown to possess anti-inflammatory activity. The chromatographic fractionation and subsequent analysis of the spectroscopic data of this extract led to the isolation and identification of ...

    journal_title:Planta medica

    pub_type: 杂志文章

    doi:10.1055/s-2003-42794

    authors: Fotsing MT,Yankep E,Njamen D,Fomum ZT,Nyasse B,Bodo B,Recio MC,Giner RM,Ríos JL

    更新日期:2003-08-01 00:00:00

  • Development of in vitro techniques for the important medicinal plant Veratrum californicum.

    abstract::VERATRUM CALIFORNICUM (Liliaceae) is an important monocotyledonous medicinal plant which is the only source of the anticancer compound cyclopamine. An IN VITRO culture system for somatic embryogenesis and green plant regeneration of VERATRUM CALIFORNICUM was developed. Embryogenic calli were induced from mature embryo...

    journal_title:Planta medica

    pub_type: 杂志文章

    doi:10.1055/s-2006-946697

    authors: Ma R,Ritala A,Oksman-Caldentey KM,Rischer H

    更新日期:2006-10-01 00:00:00

  • Arbuscular mycorrhizal inoculation enhances survival rates and growth of Micropropagated plantlets of Echinacea pallida.

    abstract::In an attempt to induce positive effects on the acclimatization of in vitro propagated Echinacea pallida, four arbuscular mycorrhizal (AM) fungi, Glomus mosseae, Gigaspora ramisporophora, Scutellospora fulgida and Entrophospora colombiana were selected to aid the soil adaptation process. Fungal inocula affected the su...

    journal_title:Planta medica

    pub_type: 信件

    doi:10.1055/s-2003-41124

    authors: Lata H,De Andrade Z,Schaneberg B,Bedir E,Khan I,Moraes R

    更新日期:2003-07-01 00:00:00

  • Effects of baicalin on airway remodeling in asthmatic mice.

    abstract::Airway remodeling is an important characteristic of asthma, linking inflammation with airway hyperresponsiveness. Baicalin, a major active component, was isolated from Radix Scutellariae. Many studies show that baicalin has anti-inflammatory, anti-bacterial, and anti-allergic effects. Here we investigate the influence...

    journal_title:Planta medica

    pub_type: 杂志文章

    doi:10.1055/s-0032-1328197

    authors: Sun J,Li L,Wu J,Liu B,Gong W,Lv Y,Luo Q,Duan X,Dong J

    更新日期:2013-03-01 00:00:00

  • Polyclonal antibody against a complement-activating pectin from the roots of Angelica acutiloba.

    abstract::Anti-sera against a complement-activating pectin (AR-2IIb), which was purified from the roots of Angelica acutiloba Kitagawa, were obtained by immunization of rabbits, and a polyclonal anti-AR-2IIb antibody of the IgG class was purified by affinity chromatography on AR-2IIb-immobilized Sepharose and Protein G-Sepharos...

    journal_title:Planta medica

    pub_type: 杂志文章

    doi:10.1055/s-2006-959524

    authors: Wang NL,Kiyohara H,Matsumoto T,Otsuka H,Hirano M,Yamada H

    更新日期:1994-10-01 00:00:00

  • Antiplasmodial activity of the alkaloids of Peschiera fuchsiaefolia.

    abstract::The tertiary and quaternary alkaloids isolated from the stem bark, root bark and seeds of Peschiera fuchsiaefolia are reported. The tertiary alkaloid crude extract from the stem bark was tested in vitro against Plasmodium falciparum on the basis of the antimalarial use of the plant. It showed good activity against bot...

    journal_title:Planta medica

    pub_type: 信件

    doi:10.1055/s-0029-1243122

    authors: Federici E,Palazzino G,Nicoletti M,Galeffi C

    更新日期:2000-02-01 00:00:00

  • A beta-Hydroxychalcone from Leptospermum scoparium.

    abstract::A beta-hydroxychalcone 1, so far not reported as a natural compound, was separated from the diethyl ether extract of LEPTOSPERMUM SCOPARIUM (Myrtaceae). Furthermore, three known flavonoids 2-4 were isolated. The (13)C-NMR spectra of 2-4 are reported, since they have as yet not been reported in the literature. ...

    journal_title:Planta medica

    pub_type: 杂志文章

    doi:10.1055/s-2006-959667

    authors: Mayer R

    更新日期:1993-06-01 00:00:00

  • A new lignan glycoside from Eleutherococcus senticosus.

    abstract::A new lignan glycoside, named eleutheroside E(2) (1), has been isolated from the roots of Eleutherococcus senticosus (known as "Siberian ginseng"), along with isomaltol 3-O-alpha-D-glucopyranoside (2), eleutherosides B, E and E(1), and thymidine. The structure of 1 was established by spectral interpretations as episyr...

    journal_title:Planta medica

    pub_type: 杂志文章

    doi:10.1055/s-2001-18352

    authors: Li XC,Barnes DL,Khan IA

    更新日期:2001-11-01 00:00:00

  • Diterpenoids from Turraeanthus mannii.

    abstract::Three new compounds, 15-acetoxy-12-hydroxy-16-methyl-labda-8(17),13E-diene (1), ent-labda-8(17),13-dien-15,16-olid-19-oic acid methyl ester (2), and 12-hydroxy-labda-8(17),13-dien-15,16-olide (3), together with two known compounds, 19-acetoxy-ent-labda-8(17),13-dien-15,16-olide (4), and 16-acetoxy-12,15-epoxy-15beta-h...

    journal_title:Planta medica

    pub_type: 杂志文章

    doi:10.1055/s-2007-967170

    authors: Vardamides JC,Sielinou VT,Ndemangou B,Nkengfack AE,Fomum ZT,Poumale HM,Laatsch H

    更新日期:2007-05-01 00:00:00

  • Chemical properties and anti-complementary activities of polysaccharide fractions from roots and leaves of Panax ginseng.

    abstract::Water-soluble and alkaline-soluble polysaccharide fractions, prepared from roots and leaves of PANAX GINSENG C.A. Meyer, were fractionated into strongly acidic, weakly acidic, and neutral polysaccharide fractions by cetyltrimethyammonium bromide, respectively. The roots contained a larger amount of crude polysaccharid...

    journal_title:Planta medica

    pub_type: 杂志文章

    doi:10.1055/s-2006-961765

    authors: Gao QP,Kiyohara H,Cyong JC,Yamada H

    更新日期:1989-02-01 00:00:00

  • Antitrypanosomal isothiocyanate and thiocarbamate glycosides from Moringa peregrina.

    abstract::O-Methyl (1), O-ethyl (2), and O-butyl (3) 4-[(α-L-rhamnosyloxy) benzyl] thiocarbamate (E), along with 4-(α-L-rhamnosyloxy) benzyl isothiocyanate (4) have been isolated from the aerial parts of Moringa peregrina. The compounds were tested for in vitro activity against Trypanosoma brucei rhodesiense and cytotoxicity in...

    journal_title:Planta medica

    pub_type: 杂志文章

    doi:10.1055/s-0033-1351102

    authors: Ayyari M,Salehi P,Ebrahimi SN,Zimmermann S,Portmann L,Krauth-Siegel RL,Kaiser M,Brun R,Rezadoost H,Rezazadeh S,Hamburger M

    更新日期:2014-01-01 00:00:00

  • Differentiation of the traditional Chinese medicinal plants Euphorbia humifusa and E. maculata from adulterants by TaqMan real-time polymerase chain reaction.

    abstract::DNA sequence analysis of the rDNA internal transcribed spacer 1 (ITS1) and TaqMan real-time polymerase chain reaction were exploited for their applications in the differentiation of the traditional chinese medicinal plants euphorbia humifusa and e. maculata from three related adulterants e. hypericifolia, E. atoto and...

    journal_title:Planta medica

    pub_type: 杂志文章

    doi:10.1055/s-2008-1034305

    authors: Xue HG,Wang H,Li DZ,Xue CY,Wang QZ

    更新日期:2008-02-01 00:00:00