Abstract:
:The effects of four fractions, a hexane fraction, an ethyl acetate fraction, an N-butanol fraction and a water fraction, from a water extract of Herba Visci were investigated to find the fraction, in IN VITRO experiments, with the greatest ability to inhibit the formation of osteoclast-like multinucleated cells from mouse bone marrow cells and also to inhibit (45)Ca release from a mouse parietal bone organ culture system. The ethyl acetate fraction was able to inhibit the formation of osteoclast-like cells in a dose-dependent manner and was also able to potently inhibit the release of (45)Ca even at a low concentration. Therefore, a further IN VIVO experiment was performed to determine if the ethyl acetate fraction had antiosteoporotic activity. It was found to inhibit the decreases in total and cancellous bone mineral density, in cancellous and cortical bone mineral content as well as in cortical bone thickness and in the X-axis strength index of tibiae of ovariectomized rats. The principle constituents of the ethyl acetate fraction were determined to be (+)-syringaresinol O- beta-glucopyranoside, 2-homoeriodictyol 7- O-glucoside and viscumneoside I by HPLC analysis.
journal_name
Planta Medjournal_title
Planta medicaauthors
Yin J,Han N,Xu X,Liu Z,Zhang B,Kadota Sdoi
10.1055/s-2008-1034283subject
Has Abstractpub_date
2008-02-01 00:00:00pages
120-5issue
2eissn
0032-0943issn
1439-0221journal_volume
74pub_type
杂志文章相关文献
PLANTA MEDICA文献大全abstract::A new cytotoxic cyclopenta[b]benzofuran derivative, aglaiformosanin (1) and three known cyclopenta[b]benzofuran derivatives (2 - 4) were isolated from the stem bark of Aglaia formosana. Compounds 1 - 4 exhibited potent cytotoxicity against the P-388, KB, HT-29, HL-60, and A549 cell lines. The structure of compound 1 w...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2001-16471
更新日期:2001-08-01 00:00:00
abstract::The aim of this study was to evaluate the effects of 7-epiclusianone (7-epi) on specific virulence attributes of Streptococcus mutans in vitro and on development of dental caries in vivo. 7-Epi was obtained and purified from fruits of Rheedia brasiliensis. We investigated its influence on surface-adsorbed glucosyltran...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0030-1250121
更新日期:2011-01-01 00:00:00
abstract::The present study is aimed at evaluating the effects of luteolin on the scratching behavior associated with an allergic cutaneous reaction in mice. Elicitation of passive cutaneous anaphylaxis, and intradermal injections of compound 48/80, histamine or serotonin induced scratching behavior in ICR mice. Models of irrit...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2005-864137
更新日期:2005-05-01 00:00:00
abstract::The configurations of the component amino acids in ginseng tetrapeptide 1 isolated from Panax ginseng were determined by HPLC with an optical resolution column and the structure of 1 was established to be H-L-Val-gamma-D-Glu-D-Arg- Gly-OH. Synthesis of the ginseng tetrapeptide, 1, and of the configuration and conjugat...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957830
更新日期:1996-04-01 00:00:00
abstract::Three new sauchinone analogues, sauchinones B-D (1-3), together with sauchinone (4), were isolated from the aerial part of Saururus chinensis. Structures of the new compounds were determined by extensive spectroscopic data as well as X-ray analysis. Compounds 3 and 4 inhibited nitric oxide production in lipopolysaccha...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0033-1351053
更新日期:2013-12-01 00:00:00
abstract::As an exploratory investigation of antimicrobial promoting compounds, 3- O-acyl-(-)-epicatechins and 3- O-acyl-(+)-catechins possessing various aromatic groups and aliphatic chains of varying length from C4 to C16 for increasing lipophilicity were synthesized and tested for antimicrobial activities against Gram-positi...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2004-818923
更新日期:2004-03-01 00:00:00
abstract::P57AS3 (P57), an oxypregnane steroidal glycoside, is known to be responsible for the appetite suppressing activity of HOODIA GORDONII, a dietary supplement used for weight loss. In this study, bioavailability, pharmacokinetics, and tissue distribution of P57 were determined in CD1 female mice after administration of a...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0030-1249818
更新日期:2010-10-01 00:00:00
abstract::Synthetic butylidenephthalide (Bdph), 60 mg/kg per os (p.o.) given 3 h prior to injection of pituitrin (4 U/kg, i.v.), significantly prevented T-wave lowering on lead II electrocardiograph in unanesthetized rats. The effective dose, 60 mg/kg, was about 1/56th of the median lethal dose (LD50, p.o.) in rats. However, Bd...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957415
更新日期:1998-04-01 00:00:00
abstract::The essential oil composition of three Zingiberaceae widely used as medicinal aromatic plants from S. Tomé and Príncipe: Aframomum danielli (Hook. f.) K. Schum., Curcuma longa L. and Zingiber officinale Rosc. was studied. Two samples of the essential oils from fruit of A. danielli and from rhizomes of the other two sp...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2001-16494
更新日期:2001-08-01 00:00:00
abstract::A beta-hydroxychalcone 1, so far not reported as a natural compound, was separated from the diethyl ether extract of LEPTOSPERMUM SCOPARIUM (Myrtaceae). Furthermore, three known flavonoids 2-4 were isolated. The (13)C-NMR spectra of 2-4 are reported, since they have as yet not been reported in the literature. ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-959667
更新日期:1993-06-01 00:00:00
abstract::During the seasons 1989-1993, Valeriana officinalis plants were investigated for their contents of essential oil, valerenic acid and derivatives, and valepotriates. Harvesting of the subterranean parts was started in August of the year in which the seeds were sown, and continued until the last week of April of the sub...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957392
更新日期:1998-03-01 00:00:00
abstract::A new minor diterpenoid alkaloid, caeruline, was isolated from DELPHINIUM CAERULEUM Jacq. ex Camb. Its structure was elucidated as 1 on the basis of spectral evidence. Along with this new compound, three known diterpenoid alkaloids were also isolated from this plant and identified as tatsiensine, delcosine, and lycoct...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-959611
更新日期:1993-02-01 00:00:00
abstract::Evodiamine, a major alkaloidal principle of Evodia fruits (Evodia rutaecarpa, Rutaceae), showed vanilloid receptor agonistic activities comparable to capsaicin. The Chinese literature refers to Evodia fruits as a "hot nature" herb. In spite of the similarities in the actions of evodiamine and capsaicin in vitro, evodi...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2001-17353
更新日期:2001-10-01 00:00:00
abstract::Five abietane diterpenes were isolated from a hexane extract obtained from the roots of Aegiphila lhotzkyana and identified as uncinatone, cyrtophyllone B, teunvicenone E, sugiol and 12,16-epoxy-11,14-dihydroxy-6-methoxy-17(15 - 16)- abeo-abieta-5,8, 11,13,15-pentaene-3,7-dione. The last compound has only been describ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2004-815499
更新日期:2004-02-01 00:00:00
abstract::Hot water extract (ALR-0) of rhizomes of Atractylodes lanceo DC. was fractionated into MeOH-soluble fraction (ALR-1), supernatant fraction of EtOH precipitation (ALR-3 + 4), and crude polysaccharide fraction (ALR-5). Among these fractions, only ALR-5 showed potent stimulating activity for proliferation of bone marrow ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957564
更新日期:1998-12-01 00:00:00
abstract::The active ingredient dl-tetrahydropalmatine (THP) isolated from the traditional Chinese herb Corydalis racemosa has been found to have antihypertensive effects. However, severe cardiac and neurological toxic effects were reported from using this herb for the treatment of pain. In an isolated perfused rat heart model,...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-1999-13998
更新日期:1999-05-01 00:00:00
abstract::Northern Labrador tea, Rhododendron tomentosum ssp. subarcticum, is one of the most commonly used medicinal plants by Inuit and other First Nations peoples of Canada. The phenolic profile and seasonal variation of this commonly used medicinal plant remains largely unknown. To assess optimal harvesting time, R. tomento...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0030-1270968
更新日期:2011-09-01 00:00:00
abstract::Jujuboside A (JuA) is a glycoside extracted from the seed of Ziziphus jujuba Mill var. spinosa (Bunge) Hu ex H F Chou, a Chinese herbal medicine, which has long been known as a sedative-hypnotic drug. The present study used the method of intracerebroventricular (i.c.v.) JuA in vivo to detect the effect of JuA on paire...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2002-34398
更新日期:2002-09-01 00:00:00
abstract::The culture medium of Beauveria amorpha Hohn. exhibited strong radical scavenging properties. Activity-directed fractionation assisted by a radical scavenging assay on TLC afforded two active compounds which were identified as 6-methyl-2,4-dihydroxyphenyl 4-O-methyl-beta-D-glucopyranoside (1) and (-)-terredionol (2). ...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2002-19868
更新日期:2002-01-01 00:00:00
abstract::Some diterpenoids show various biological activities, including anti-inflammatory, anti-HIV and anti-tumor activity. Previously, we have focused our research on the apoptosis-inducing properties of diterpenoids and found that some ent-kaurene-type diterpenoids induced apoptosis in human leukemia HL-60 cells. In this s...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2005-873133
更新日期:2005-11-01 00:00:00
abstract::Infections caused by HSV-2 are a public health concern worldwide, and there is still a great demand for the discovery of novel anti-herpes virus agents effective against strains resistant to current antiviral agents. In this context, medicinal plants represent an alternative source of active compounds for developing e...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/a-1087-8303
更新日期:2020-03-01 00:00:00
abstract::From the roots of PICRORHIZA KURROOA a new iridoid glycoside, 6-feruloylcatalpol has been isolated, along with veronicoside and minecoside and two phenol glucosides, picein and androsin. ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-962066
更新日期:1989-10-01 00:00:00
abstract::A crude polysaccharide fraction (DAP-1) was prepared from roots of Dipsacus asperoides by hot water extraction and EtOH precipitation, and tested for anti-complementary activity, mitogenic activity of lymphocytes, and effects on acid phosphatase and phagocytic activities of macrophages. DAP-1 showed not only anti-comp...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957720
更新日期:1997-10-01 00:00:00
abstract::A method was developed to distinguish Vaccinium species based on leaf extracts using nuclear magnetic resonance spectroscopy. Reference spectra were measured on leaf extracts from several species, including lowbush blueberry (Vaccinium angustifolium), oval leaf huckleberry (Vaccinium ovalifolium), and cranberry (Vacci...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0034-1368569
更新日期:2014-06-01 00:00:00
abstract::A crude globulin fraction was isolated from the tubers of Pinellia ternata (Thunb.) Breit. Tubers of P. ternata are one of the well known Chinese traditional medicines. It is used on account of its anti-emetic effect. 6KDP was separated by means of gel filtration and chromatography on CM-Toyopearl 650 M from the crude...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957539
更新日期:1998-10-01 00:00:00
abstract::The analysis of the volatile compounds in the essential oil of SOLIDAGO CANADENSISL. sensu lato (Compositae) GC and GC-MS demonstrated the presence of at least 36 compounds, 18 of which were identified. The Major comonenets are gamma (2)- and delta-cadinenes. ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-960930
更新日期:1990-04-01 00:00:00
abstract::Cissampentine A (1), an enantiomer of cissampentin, three new cycleatjehenine-type bisbenzylisoquinoline alkaloids, cissampentine B-D (2-4), and five known alkaloids were isolated from the roots of Cyclea tonkinensis. Their structures were established by interpretation of NMR, high-resolution ESI-MS data, and CD spect...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0035-1545882
更新日期:2015-05-01 00:00:00
abstract::Bioassay-guided fractionation of the anti-HIV-1 active EtOAc extract from leaves and twigs of Ochna integerrima led to the isolation of five new flavonoid glycosides 1 - 5, five known flavonoids 6 - 10, and two known flavonoid glycosides 11 and 12. Structures were determined based on spectroscopic analyses. 6- gamma, ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-981538
更新日期:2007-06-01 00:00:00
abstract::Bioassay directed fractionation of the (1:1) chloroform-methanol extract of Gentiana spathacea H.B.K (Gentianaceae) led to the isolation of gentiopicroside (gentiopricrin) (1), the major spasmolytic component of the plant. Gentiopicroside inhibited, in a concentration-dependent manner, the spontaneous contractions of ...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2000-9774
更新日期:2000-12-01 00:00:00
abstract::Seven coumarins were isolated from the aerial parts of Tordylium apulum; their structures were established by spectroscopic means. All compounds were tested in vitro for their cytotoxicity against two cell line systems. The antiproliferative effects for three of them were studied at the level of the cell cycle in asyn...
journal_title:Planta medica
pub_type: 信件
doi:
更新日期:1998-03-01 00:00:00