Smooth muscle relaxing activity of gentiopicroside isolated from Gentiana spathacea.

abstract：:A quantitative analysis using (1)H-NMR (Q-NMR) has been developed for the determination of strychnine and brucine in Strychnos nux-vomica seeds and stems. The advantages of the method are that no reference alkaloids are needed for calibration curves, the quantification could be directly realized on a crude extract, st...

journal_title：Planta medica

authors： Frédérich M,Choi YH,Verpoorte R

更新日期：2003-12-01 00:00:00

abstract：:The antioxidant effects of 1,5-anhydro-D-fructose (1,5-AF), a unique anhydrohexulose, were studied in 1,1-diphenyl-2-picrylhydrazyl (DPPH) solution, in human cells along with lipid peroxidation of low-density lipoprotein (LDL). We have confirmed that 1,5-AF scavenges DPPH radicals directly in solution and inhibits the...

journal_title：Planta medica

authors： Yamaji K,Sarker KP,Maruyama I,Hizukuri S

更新日期：2002-01-01 00:00:00

abstract：:Six dietary isothiocyanates, allyl-isothiocyanate, benzyl-isothiocyanate, phenylethyl-isothiocyanate, sulforaphane, erucin, and iberin, were tested for their trypanocidal activities in vitro using culture-adapted bloodstream forms of Trypanosoma brucei. All isothiocyanates showed a dose-dependent effect on the growth ...

journal_title：Planta medica

authors： Steverding D,Michaels S,Read KD

更新日期：2014-02-01 00:00:00

abstract：:Two new lignans, (-)-aptosimon ( 1) and (-)-diasesamin-di-gamma-lactone ( 2), together with twenty-two known compounds, have been isolated from the stems and roots of Wikstroemia lanceolata. The structures of the new compounds were determined through spectral analyses. The proton and carbon assignments of the known se...

journal_title：Planta medica

authors： Lin RW,Tsai IL,Duh CY,Lee KH,Chen IS

更新日期：2004-03-01 00:00:00

abstract：:A cytotoxic compound was purified from the root of Angelica gigas Nakai by normal phase HPLC. As a result of the structure analysis by mass, IR, 1H-NMR, and 13C-NMR spectrometry, the compound was identified as decursinol angelate, a structural isomer of decursin, and characterized originally from Sesei grandivittatum....

journal_title：Planta medica

authors： Ahn KS,Sim WS,Lee IK,Seu YB,Kim IH

更新日期：1997-08-01 00:00:00

abstract：:Four new isoprenylated xanthones, cudraxanthones A, B and C were isolated from the N-hexane extract of the root bark of CUDRANIA TRICUSPIDATA (Carr.) Bur. (Japanese name "Hariguwa"; Moraceae), and cudraxanthone D from the benzene extract. The structures of cudraxanthones A, B, C and D were shown to be 1-4, respectivel...

journal_title：Planta medica

authors： Fujimoto T,Hano Y,Nomura T

更新日期：1984-06-01 00:00:00

abstract：:From the stem bark of Strychnos malacoclados, one new bisindole alkaloid, 3-hydroxylongicaudatine Y (1), was isolated along with the known alkaloids vomicine (2), bisnordihydrotoxiferine (3), divarine (4), longicaudatine (5), longicaudatine Y (6), and longicaudatine F (7). All the compounds were tested for their antim...

journal_title：Planta medica

authors： Tchinda AT,Ngono AR,Tamze V,Jonville MC,Cao M,Angenot L,Frédérich M

更新日期：2012-03-01 00:00:00

abstract：:A method was developed to distinguish Vaccinium species based on leaf extracts using nuclear magnetic resonance spectroscopy. Reference spectra were measured on leaf extracts from several species, including lowbush blueberry (Vaccinium angustifolium), oval leaf huckleberry (Vaccinium ovalifolium), and cranberry (Vacci...

journal_title：Planta medica

authors： Markus MA,Ferrier J,Luchsinger SM,Yuk J,Cuerrier A,Balick MJ,Hicks JM,Killday KB,Kirby CW,Berrue F,Kerr RG,Knagge K,Gödecke T,Ramirez BE,Lankin DC,Pauli GF,Burton I,Karakach TK,Arnason JT,Colson KL

更新日期：2014-06-01 00:00:00

abstract：:From the water extract of the roots of Urtica dioica (stinging nettle) a polysaccharide fraction was isolated which revealed activity in the carrageenan rat paw edema model and lymphocyte transformation test. Ion exchange chromatography and gel filtration of this fraction afforded 4 different polysaccharides, one of w...

journal_title：Planta medica

authors： Wagner H,Willer F,Kreher B

更新日期：1989-10-01 00:00:00

abstract：:Three new guaiane-type sesquiterpene lactones (1-3), together with nine related sesquiterpenes (4-12), were isolated from the whole extract of Ixeris dentata (Asteraceae). The chemical structures of isolates 1-12 were established by spectroscopic analyses as 3 β,8 β-dihydroxy-guaia-10(14)-en-1 α,4 α,5 α,6 β,7 α,11 βH-...

journal_title：Planta medica

authors： Cha MR,Choi YH,Choi CW,Yoo DS,Kim YS,Choi SU,Kim YH,Ryu SY

更新日期：2011-03-01 00:00:00

abstract：:An ionpair-HPLC-technic using a reversed-phase column was developed to screen plant extracts for cardiotonic amines and to isolate them in a preparative scale for direct MS and pharmacological investigations. By this method the positive inotropic tyramine could be isolated from Selenicereus grandiflorus (L.) Britt et ...

journal_title：Planta medica

authors： Wagner H,Grevel J

更新日期：1982-01-01 00:00:00

abstract：:Several synthetic aromatase inhibitors are currently in clinical use for the treatment of postmenopausal women with hormone-receptor positive breast cancer. However, these treatments may lead to untoward side effects and so the search for new aromatase inhibitors continues, especially those for which the activity is p...

journal_title：Planta medica

authors： Balunas MJ,Kinghorn AD

更新日期：2010-08-01 00:00:00

abstract：:Extraction of PIPER RIBESOIDES Wall, furnished the new linalool derivative (+)-3,7-dimethyl-3-hydroxy-4-( P-coumaryloxy)-1,6-octadiene, the lignans (-)-hinokinin and (-)-cubebin, N-isobutyl-2 E,4 E-deca-2,4-dienamide, methyl piperate, methyl 2 E,4 E,6 E-7-phenyl-2,4,6-heptatrienoate, palmitic acid, stearic acid, and b...

journal_title：Planta medica

authors： Kijjoa A,Pinto MM,Tantisewie B,Herz W

更新日期：1989-04-01 00:00:00

abstract：:The cytotoxicity of goniothalamin was found to be strong towards both cancerous (HGC-27, MCF-7, PANC-1, HeLa), and non-cancerous (3T3) cell lines, especially in cases of dividing cells. Drug exposure studies indicated that the cytotoxic action of goniothalamin was time- and dose-dependent. At the ultrastructural level...

journal_title：Planta medica

authors： Ali AM,Mackeen MM,Hamid M,Aun QB,Zauyah Y,Azimahtol HL,Kawazu K

更新日期：1997-02-01 00:00:00

abstract：:Gas chromatography-flame ionization detection (GC-FID) was used to assess the chemical profile and quantification of cannabinoids to identify the differences, if existing, in the chemical constituents of in vitro propagated plants (IVP), conventionally grown plants (VP) and indoor grown mother plants (MP-Indoor) of a ...

journal_title：Planta medica

authors： Chandra S,Lata H,Mehmedic Z,Khan IA,ElSohly MA

更新日期：2010-05-01 00:00:00

abstract：:Based on rDNA ITS sequences of D. officinale and the other 37 species of Dendrobium, a pair of allele-specific diagnostic primers, TP-JB01S and TP-JB01X, were designed to authenticate D. officinale from the other species. Before the diagnostic PCR, the primer pair, P1 and P2, for amplifying the whole ITS region was us...

journal_title：Planta medica

authors： Ding X,Wang Z,Zhou K,Xu L,Xu H,Wang Y

更新日期：2003-06-01 00:00:00

abstract：:Three new azaphilones, chaetomugilin S (1), 7,5'-bis-epi-chaetoviridin A (2), and 7-epi-chaetoviridin E (3), and two new chlorinated phenolic glycosides, globosumoside A (4) and globosumoside B (5), were isolated from the crude extract of the fungal strain Chaetomium elatum No. 89-1-3-1. Their structures were determin...

journal_title：Planta medica

authors： Chen GD,Li YJ,Gao H,Chen Y,Li XX,Li J,Guo LD,Cen YZ,Yao XS

更新日期：2012-10-01 00:00:00

abstract：:Accumulation of furanic labdane diterpenes has been investigated in different parts of field-grown plants of MARRUBIUM VULGARE (Lamiaceae) and LEONURUS CARDIACA (Lamiaceae). Furanic labdane diterpenes were produced and accumulated only in the aerial parts. Greatest amounts were measured in leaves and flowers. Up to 4 ...

journal_title：Planta medica

authors： Knöss W,Zapp J

更新日期：1998-05-01 00:00:00

abstract：:Six pentacyclic triterpenic acid methyl esters have been isolated from the methylated ethyl acetate extract of the trunk wood of MUSANGA CECROPIOIDES, as well as a triterpene saponin of the same group. One of them, cecropic acid methyl ester, is new. The structures of these compounds have been established from interpr...

journal_title：Planta medica

authors： Lontsi D,Sondengam BL,Ayafor JF,Tsoupras MG,Tabacchi R

更新日期：1990-06-01 00:00:00

abstract：:In the extremely skin irritant and caustic latex of Excoecaria agallocha the major part of the polyfunctional diterpene esters (DTE) (group I) are aliphatic polyunsaturated 9,13,14-orthoesters of the daphnane-type parent alcohol 5 beta-hydroxyresiniferonol-6 alpha, 7 alpha-epoxide, esterified simultaneously in their 2...

journal_title：Planta medica

authors： Karalai C,Wiriyachitra P,Opferkuch HJ,Hecker E

更新日期：1994-08-01 00:00:00

abstract：:Natural compounds have been the first historical source of antithrombotic compounds (heparin, vitamin K antagonists, streptokinase, urokinase); molecules extracted from plants or animals still provide some of the most original and promising approaches for the discovery of new drugs in this class. In this review, we wi...

journal_title：Planta medica

authors： Beretz A,Cazenave JP

更新日期：1991-10-01 00:00:00

abstract：:One hundred and thirty-eight medicinal herbal drugs obtained from different suppliers were examined for microbial contaminants and for the detectability of pathogenic microorganisms. For this purpose, several microbiological standard parameters (total aerobic mesophilic count, enterobacteria, coliforms, aerobic sporef...

journal_title：Planta medica

authors： Czech E,Kneifel W,Kopp B

更新日期：2001-04-01 00:00:00

abstract：:In this study, the significant hepatoprotective effect of dioscin against CCl₄-induced acute liver damage in mice was first discovered, and the effect produced by dioscin at the dose of 100 mg/kg was equal to the action produced by silymarin at the dose of 200 mg/kg. Then, 1-dimension gel electrophoresis was used to s...

journal_title：Planta medica

authors： Lu B,Yin L,Xu L,Peng J

更新日期：2011-03-01 00:00:00

abstract：:Shoot-tips from several genotypes of the cardenolide-producing perennial shrub Digitalis obscura L. were successfully cryopreserved using the encapsulation-dehydration technique. Precultivation on MS medium containing 0.5 M sucrose, followed by 2.5 h dehydration (final weight 30 %) induced shoot regrowth in 42 % of cr...

journal_title：Planta medica

authors： Sales E,Nebauer SG,Arrillaga I,Segura J

更新日期：2001-12-01 00:00:00

abstract：:Eleven sesquiterpenoids have been isolated from the whole plants of Youngia japonica (Asteraceae). Among these sesquiterpenoids, five were identified as new compounds on the basis of spectroscopic methods and chemical analysis. Their structures were 3-oxo-8alpha-(4-hydoxyphenyl)acetoxy-10(14),11(13)-guaiadien-12,6-oli...

journal_title：Planta medica

authors： Chen W,Liu Q,Wang J,Zou J,Meng D,Zuo J,Zhu X,Zhao W

更新日期：2006-02-01 00:00:00

abstract：:The immunomodulatory activity of HN-02, an extract containing a mixture of andrographolides (i.e., andrographolide [88 +/- 5 %] plus 14-deoxyandrographolide and 14-deoxy-11,12-didehydroandrographolide together [12 +/- 3 %]) in a pure powder form was evaluated at 1.0, 1.5, and 2.5 mg/kg on different in vivo and in vitr...

journal_title：Planta medica

authors： Naik SR,Hule A

更新日期：2009-06-01 00:00:00

abstract：:High molecular compounds from Chinese herbal medicines, including ribosome-inactivating proteins and polysaccharides from both fungi and high plants have been tested for the treatment of malignant diseases. Polysaccharides possessing immunostimulating activities can be used as adjuvants in tumor treatment. The fungi c...

journal_title：Planta medica

authors： Tang W,Hemm I,Bertram B

更新日期：2003-03-01 00:00:00

abstract：:Many anti-inflammatory agents are known to significantly enhance the terminal differentiation of some cancer cells such as leukemia cells. In this study, the effect of yomogin, a eudesmane sesquiterpene lactone isolated from Artemisia princeps with anti-inflammatory activity, was investigated in human promyelocytic le...

journal_title：Planta medica

authors： Kim SH,Kim TS

更新日期：2002-10-01 00:00:00

abstract：:Two new steroidal saponins, diosbulbisides D (1) and E (2), along with five known saponins (3- 7) were isolated from the rhizomes of Dioscorea bulbifera L. Their structures were elucidated on the basis of spectral data. Compounds 6 and 7, two 3- O-trisaccharides of diosgenin spirostanes, showed moderate cytotoxic acti...

journal_title：Planta medica

authors： Liu H,Chou GX,Wang JM,Ji LL,Wang ZT

更新日期：2011-05-01 00:00:00

abstract：:The structure of swertiaside, a new iridoid glucoside isolated from SWERTIA JAPONICA, was elucidated to be 7-epi-( M-hydroxybenzoyl)-loganicacid. ...

journal_title：Planta medica

authors： Ikeshiro Y,Tomita Y

更新日期：1984-12-01 00:00:00