[New quinones in Rubia cordifolia L. Roots, III].

abstract：:Bisbenzylisoquinoline alkaloids are known to affect immune responses as well as inflammatory responses, and have been used for the treatment of inflammatory symptoms in China. This study is aimed at elucidating the inhibitory effects of two alkaloids, fangchinoline and isotetrandrine, on the induction of the proinflam...

journal_title：Planta medica

authors： Onai N,Tsunokawa Y,Suda M,Watanabe N,Nakamura K,Sugimoto Y,Kobayashi Y

更新日期：1995-12-01 00:00:00

abstract：:Olive oil has been shown to exhibit beneficial effects in the prevention of cardiovascular diseases although its molecular mechanism still remains unclear. In the present study, we investigated the effect of hydroxytyrosol (HT), a major phenolic component in olive oil and leaves from OLEA EUROPAEA L. (Oleaceae family...

journal_title：Planta medica

authors： Zrelli H,Matsuka M,Araki M,Zarrouk M,Miyazaki H

更新日期：2011-10-01 00:00:00

abstract：:Propolis has been reported to display a broad spectrum of biological activities such as anticancer, antioxidant, anti-inflammatory, antibiotic and antifungal properties, among others. There is great interest not only in the determination of the chemical composition of propolis but also in the understanding of the mech...

journal_title：Planta medica

authors： Tavares DC,Lira WM,Santini CB,Takahashi CS,Bastos JK

更新日期：2007-12-01 00:00:00

abstract：:Nine isoflavonoids including a new pterocarpene, puemiricarpene, were isolated from the tuberous root of Pueraria mirifica (Leguminosae). The structure of puemiricarpene was determined by spectroscopic means. Estrogenic activity of the isolated isoflavonoids was tested using MCF-7 human breast cancer cells. Moderate a...

journal_title：Planta medica

authors： Chansakaow S,Ishikawa T,Sekine K,Okada M,Higuchi Y,Kudo M,Chaichantipyuth C

更新日期：2000-08-01 00:00:00

abstract：:From the roots of Aconitum crassicaule, two new diterpenoid alkaloids, crassicaulisine and crassicaulidine, were isolated. The structure of crassicaulisine, C (24)H (39)O (7)N, has been elucidated as 3 on the basis of chemical and spectral data, while the structure of crassicaulidine, C (24)H (39)O (8)N, has been show...

journal_title：Planta medica

authors： Fengpeng W,Qicheng F

更新日期：1983-01-01 00:00:00

abstract：:We report a sensitive method for the estimation of quinine (Qn), cinchonine (Cn), and cinchonidine (Cnd) and a new method based on fluorescence enhancement and detection and quantification of quinidine (Qnd) from Cinchona stem bark and its formulations, using HPTLC. Standard solutions of Qn, Qnd, Cn, and Cnd were appl...

journal_title：Planta medica

authors： Ravishankara MN,Shrivastava N,Padh H,Rajani M

更新日期：2001-04-01 00:00:00

abstract：:Tuberculosis, also called TB, is currently a major health hazard due to multidrug-resistant forms of bacilli. Global efforts are underway to eradicate TB using new drugs with new modes of action, higher activity, and fewer side effects in combination with vaccines. For this reason, unexplored new sources and previousl...

journal_title：Planta medica

authors： Santhosh RS,Suriyanarayanan B

更新日期：2014-01-01 00:00:00

abstract：:The inhibitory action of the major constituent of Sebastiania schottiana (Euphorbiaceae), 2-hydroxy-4,6-dimethoxyacetophenone (xanthoxyline) on contractions induced by agonists and electrical stimulation of smooth and cardiac muscle preparations was analysed. Xanthoxyline (30 to 300 microM) inhibited contractions of t...

journal_title：Planta medica

authors： Calixto JB,Miguel OG,Yunes RA,Rae GA

更新日期：1990-02-01 00:00:00

abstract：:A new steroidal saponin, timosaponin F, along with six known compounds was isolated from the rhizomes of Anemarrhena asphodeloides Bge. On the basis of chemical and spectroscopic evidence, the structure of timosaponin F was elucidated as (5beta, 25 S):-spirostan-3beta,15alpha,23alpha-triol-3-O-beta- glucopyranosyl-(1-...

journal_title：Planta medica

authors： Meng ZY,Zhang JY,Xu SX,Sugahara K

更新日期：1999-10-01 00:00:00

abstract：:A pyrolytic gaschromatographic process was developed for the routine assay of both cyclodextrin inclusion complexes, and for the differentiation of the mechanical mixture of the same oil with beta-cyclodextrin. The method is a direct assay of low material demand. ...

journal_title：Planta medica

authors： Pobozsny K,Kernóczi L,Tétényi P,Héthelyi I,Szejtli J

更新日期：1981-07-01 00:00:00

abstract：:Three new glycosides, 1,4,8-trihydroxynaphthalene-1-O-D-glucopyranosyl-(1-->6)-beta-D- xylopyranoside (1), 1,4,8-trihydroxynaphthalene-1-O-beta-D-glucopyranosyl-(1-->6)-alph a-L- arabinopyranoside (2), 1-hydroxy-4-methoxynaphthalene-1-O-beta-D-glucopyranosyl-(1-->6)- alpha-L-rhamnopyranoside (3), were isolated from th...

journal_title：Planta medica

authors： Lee SW,Lee KS,Son JK

更新日期：2000-03-01 00:00:00

abstract：:One new drimane-type sesquiterpenoid, 3 β-angeloyloxy-7-epifutronolide (1), and one new natural product, polygonumate (2), along with six known drimane-type sesquiterpenes [dendocarbin L (3), (+) winterin (4), (+) fuegin (5), changweikangic acid A (6), futronolide (7), and 7-ketoisodrimenin (8)] were isolated from the...

journal_title：Planta medica

authors： Sultana R,Hossain R,Adhikari A,Ali Z,Yousuf S,Choudhary MI,Ali MY,Zaman MS

更新日期：2011-11-01 00:00:00

abstract：:Ganoderan B increased the plasma insulin level in normal and glucose-loaded mice but elicited no effect on insulin binding to isolated adipocytes. Administration of ganoderan B elicited significant increases of the activities of hepatic glucokinase, phosphofructokinase and glucose-6-phosphate dehydrogenase, decreased ...

journal_title：Planta medica

authors： Hikino H,Ishiyama M,Suzuki Y,Konno C

更新日期：1989-10-01 00:00:00

abstract：:Reduced estrogen levels occurring during menopause in woman are accompanied by a variety of disorders, e. g., hot flushes, depressions, osteoporosis, increase of body weight, and reduced movement drive. In this study we investigated the combined effects of physical activity, estradiol substitution, and a phytoestrogen...

journal_title：Planta medica

authors： Hertrampf T,Degen GH,Kaid AA,Laudenbach-Leschowsky U,Seibel J,Di Virgilio AL,Diel P

更新日期：2006-05-01 00:00:00

abstract：:A new indole alkaloid, galanthindole, was isolated from Galanthus plicatus ssp. byzantinus (Amaryllidaceae), a plant native to northwestern Turkey. Incorporating a non-fused indole ring, galanthindole may represent the prototype of a new subgroup of the Amaryllidaceae alkaloids. Two other bases, (+)-11-hydroxyvittatin...

journal_title：Planta medica

authors： Unver N,Kaya GI,Werner C,Verpoorte R,Gözler B

更新日期：2003-09-01 00:00:00

abstract：:Two new compounds, methyl 3-chloro-6-hydroxy-2-(4-hydroxy-2-methoxy-6-methylphenoxy)-4-methoxybenzoate (1) and (2 S,5' R,E)-7-hydroxy-4,6-dimethoxy-2-(1-methoxy-3-oxo-5-methylhex-1-enyl)-benzofuran-3(2H)-one (2), together with four known compounds, griseofulvin (3), dechlorogriseofulvin (4), bostrycin (5), and deoxybo...

journal_title：Planta medica

authors： Xia X,Li Q,Li J,Shao C,Zhang J,Zhang Y,Liu X,Lin Y,Liu C,She Z

更新日期：2011-10-01 00:00:00

abstract：:Stem extracts of Styrax camporum Pohl and Caesalpinia ferrea Martius were administered orally and intraperitoneally to rats and effected a decrease in the acute ulceration number. The volume, pH, and hydrochloric acid concentration of gastric secretions were measured after administration of both extracts, atropine, an...

journal_title：Planta medica

authors： Bacchi EM,Sertié JA

更新日期：1994-04-01 00:00:00

abstract：:Extracts from Pygeum africanum, Serenoa repens and Cucurbita pepo are used in the treatment of benign prostatic hyperplasia (BPH) and prostate cancer (PCa). The activity of the androgen receptor (AR) is known to control growth of the prostate. Here, we examined extracts of these plants for their antiandrogenic activit...

journal_title：Planta medica

authors： Schleich S,Papaioannou M,Baniahmad A,Matusch R

更新日期：2006-07-01 00:00:00

abstract：:Continued examination of the stem bark of Newbouldia laevis afforded three minor phenylethanoid glycosides, designated as newbouldiosides D - F. Their structures were elucidated by spectroscopic methods as β-(3,4-dihydroxyphenyl)ethyl 5-O-syringoyl-β-D-apiofuranosyloxy-(1 → 2)-O-[α-L-rhamnopyranosyl-(1 → 3)]-6-O-E-sin...

journal_title：Planta medica

authors： Kolodziej H

更新日期：2020-11-06 00:00:00

abstract：:In the course of our investigations on Umutambasha in order to identify its convulsant principles, small quantities of monofluoroacetate were observed in stem bark, leaves, and fruits of this plant newly identified as Dichapetalum michelsonii Hauman. Conclusive evidence for a monofluoroacetate presence came from its i...

journal_title：Planta medica

authors： Esters V,Karangwa C,Tits M,Francotte P,Pirotte B,Servais AC,Fillet M,Crommen J,Robbrecht E,Minet A,Grisar T,Angenot L,Frederich M

更新日期：2013-03-01 00:00:00

abstract：:The aim of this study was to investigate the anti-asthmatic effects of Perilla seed oil in vitro and in vivo in sensitized guinea pigs. Aerosolized antigen caused an immediate bronchoconstriction. Perilla seed oil per os inhibited the increase in lung resistance and the decrease in dynamic lung compliance in a dose-de...

journal_title：Planta medica

authors： Deng YM,Xie QM,Zhang SJ,Yao HY,Zhang H

更新日期：2007-01-01 00:00:00

abstract：:We investigated the apoptotic effects of the protopanaxadiol ginsenosides, Rb (1) and Rb (2), and their intestinal bacterial metabolite, 20-O-beta-D-glucopyranosyl-20(S)-protopanaxadiol (M1), and of the protopanaxatriol ginsenoside, Rg (1), and its intestinal bacterial metabolite, 20(S)-protopanaxatriol, in activated ...

journal_title：Planta medica

authors： Park EJ,Zhao YZ,Kim J,Sohn DH

更新日期：2006-10-01 00:00:00

abstract：:Antarctic benthic communities are regulated by abundant interactions of different types among organisms, such as predation, competition, etc. Predators are usually sea stars, with omnivorous habits, as well as other invertebrates. Against this strong predation pressure, many organisms have developed all sorts of defen...

journal_title：Planta medica

authors： Avila C

更新日期：2016-06-01 00:00:00

abstract：:Magnesium lithospermate B (MLB), sodium rosmarinate (SR), and magnesium lithospermate (ML) are biologically active components isolated from aqueous extracts of the Chinese medicine Danshen, the dried root and rhizome of SALVIA MILTIORRHIZA Bunge (Labiatae). These compounds share similar chemical structures of polyphen...

journal_title：Planta medica

authors： Chen L,Xuan LJ,Wang YP

更新日期：2009-12-01 00:00:00

abstract：:Diabetes mellitus is one of the major health problems in Africa. The conventional oral synthetic antidiabetic drugs available to manage the disease are costly and not readily affordable to the majority of the affected population. Interestingly, the continent is endowed with a tremendous number of medicinal plants that...

journal_title：Planta medica

authors： Mohammed A,Ibrahim MA,Islam MS

更新日期：2014-03-01 00:00:00

abstract：:The chemical investigation of the essential oils from the aerial organs of Bellis perennis L., the common daisy, showed that polyacetylenes were one of the dominant class of compounds. The major constituents, methyl deca-4,6-diynoate and deca-4,6-diynoic acid, and their structural analogues, deca-4,6-diyne, dimethyl o...

journal_title：Planta medica

authors： Avato P,Vitali C,Mongelli P,Tava A

更新日期：1997-12-01 00:00:00

abstract：:During the screening of antimalarial substances, the 80% EtOH extract from the outer bark of Ochna integerrima Merr. (Ochnaceae) was shown to have a good anti-malarial activity (IC50 value: 6.5 microg/mL) whereas extracts from the inner barks of O.integerrima showed no antimalarial activity. Biflavanone (1), which had...

journal_title：Planta medica

authors： Ichino C,Kiyohara H,Soonthornchareonnon N,Chuakul W,Ishiyama A,Sekiguchi H,Namatame M,Otoguro K,Omura S,Yamada H

更新日期：2006-06-01 00:00:00

abstract：:The acylphloroglucinol derivative hyperforin is a major constituent of St. John's wort extracts ( Hypericum perforatum L.), which has been demonstrated to contribute to the antidepressant action of this herbal drug. In previous investigations we observed that hyperforin causes a rapid stimulation of intracellular calc...

journal_title：Planta medica

authors： Schrattenholz A,Schroer K,Chatterjee SS,Koch E

更新日期：2004-04-01 00:00:00

abstract：:The effect of extracts of MOMORDICA CHARANTIA L. fruits on glucose metabolism and glucose uptake was investigated. The fruit of momordica, at all ripening stages, was found to contain two inhibitory compounds: one against hexokinase activity and the other against glucose uptake by rat intestinal fragments. Both inhibi...

journal_title：Planta medica

authors： Meir P,Yaniv Z

更新日期：1985-02-01 00:00:00

abstract：:Seven new clerodane diterpenoids, dysoxydensins A-G (1-7), together with six known clerodanes, were isolated from Dysoxylum densiflorum. The structures of all the compounds were elucidated by extensive spectroscopic analysis. These compounds were evaluated for their cytotoxic activities against five human cancer cell ...

journal_title：Planta medica

authors： Gu J,Cheng GG,Qian SY,Li Y,Liu YP,Luo XD

更新日期：2014-08-01 00:00:00