Drimane-type sesquiterpenes from Polygonum hydropiper.

abstract：:The ripe berries of Harrisonia abyssinica yielded two new prenylated acetophenones, namely 5-(ethan-1'''-one)-4,6-dihydroxy-7-(3'',3''-dimethylallyl)-2 S-(1' S-hydroxy-1',5'-dimethylhex-4'-enyl)-2,3-dihydrobenzofuran (1) and 5-(2'''-hydroxyethan-1'''-one)-4,6-dihydroxy-7-(3'',3''-dimethylallyl)-2 S-(1' S-hydroxy-1',5'...

journal_title：Planta medica

authors： Mayaka RK,Langat MK,Omolo JO,Cheplogoi PK

更新日期：2012-03-01 00:00:00

abstract：:The medicinal properties of curcumin obtained from Curcuma longa L. cannot be utilised because of poor bioavailability due to its rapid metabolism in the liver and intestinal wall. In this study, the effect of combining piperine, a known inhibitor of hepatic and intestinal glucuronidation, was evaluated on the bioavai...

journal_title：Planta medica

authors： Shoba G,Joy D,Joseph T,Majeed M,Rajendran R,Srinivas PS

更新日期：1998-05-01 00:00:00

abstract：:A systematic structure-activity relationship of 3beta-hydroxy-27- P- E-coumaroyloxyurs-12-en-28-oic acid ( 7), a triterpene ester isolated from UNCARIA RHYNCHOPHYLLA as a phospholipase Cgamma1 inhibitor, was undertaken with a view toward elucidating its chemical mode of action on PLCgamma1. Related derivatives and ana...

journal_title：Planta medica

authors： Lee JS,Yoo H,Suh YG,Jung JK,Kim J

更新日期：2008-10-01 00:00:00

abstract：:[6]-Gingerol potently inhibits peroxynitrite-induced oxidation and nitration reactions, but its mechanism of action is unclear. In order to discover the mechanism of inhibition, [6]-gingerol was reacted with peroxynitrite and the reaction mixture was analyzed using HPLC. The HPLC chromatogram showed one novel peak, in...

journal_title：Planta medica

authors： Ippoushi K,Ito H,Horie H,Azuma K

更新日期：2005-06-01 00:00:00

abstract：:Ideally, metabolomics should deal with all the metabolites that are found within cells and biological systems. The most common technologies for metabolomics include mass spectrometry, and in most cases, hyphenated to chromatographic separations (liquid chromatography- or gas chromatography-mass spectrometry) and nucle...

journal_title：Planta medica

authors： Ge Y,Chen X,Gođevac D,Bueno PCP,Salomé Abarca LF,Jang YP,Wang M,Choi YH

更新日期：2019-08-01 00:00:00

abstract：:In this work we studied the effect of alpha-asarone, a hypolipidemic active principle of Guatteria gaumeri Greenman, on hepatic lipid metabolism using adult rat hepatocytes cultured on a feeder layer of 3T3 cells. These cultures synthesize and secrete for at least two weeks various lipids from [14C]-acetic and [14C]-o...

journal_title：Planta medica

authors： Hernández A,López ML,Chamorro G,Mendoza-Figueroa T

更新日期：1993-04-01 00:00:00

abstract：:Transient receptor potential channels and cannabinoid receptors are deputed to the regulation of sensory, homeostatic, and inflammatory events in the human organism. Therefore, their modulation promises to have relevant applications in important therapeutic areas such as inflammation, pain, and cancer. This review sum...

journal_title：Planta medica

authors： Rigano D,Formisano C,Taglialatela-Scafati O

更新日期：2016-06-01 00:00:00

abstract：:Poncirus trifoliata (Rutaceae) extracts have been known to possess anti-allergic, anti-inflammatory and antiviral activities. However, other biological activities, especially, the anticancer potential of extracts of P. trifoliata or its constituents, have not been fully investigated yet. In this study, we have evaluat...

journal_title：Planta medica

authors： Hong J,Min HY,Xu GH,Lee JG,Lee SH,Kim YS,Kang SS,Lee SK

更新日期：2008-02-01 00:00:00

abstract：:Four new isoprenylated xanthones, cudraxanthones A, B and C were isolated from the N-hexane extract of the root bark of CUDRANIA TRICUSPIDATA (Carr.) Bur. (Japanese name "Hariguwa"; Moraceae), and cudraxanthone D from the benzene extract. The structures of cudraxanthones A, B, C and D were shown to be 1-4, respectivel...

journal_title：Planta medica

authors： Fujimoto T,Hano Y,Nomura T

更新日期：1984-06-01 00:00:00

abstract：:Gas chromatography-flame ionization detection (GC-FID) was used to assess the chemical profile and quantification of cannabinoids to identify the differences, if existing, in the chemical constituents of in vitro propagated plants (IVP), conventionally grown plants (VP) and indoor grown mother plants (MP-Indoor) of a ...

journal_title：Planta medica

authors： Chandra S,Lata H,Mehmedic Z,Khan IA,ElSohly MA

更新日期：2010-05-01 00:00:00

abstract：:Isoliquiritigenin (4,2',4'-trihydroxychalcone, ISL) is a natural pigment with a simple chalcone structure. In this study, we report the ISL-induced inhibition on the growth of human hepatoma cells (Hep G2) for the first time. The cell growth inhibition achieved by ISL treatment resulted in programmed cell death in a c...

journal_title：Planta medica

authors： Hsu YL,Kuo PL,Lin LT,Lin CC

更新日期：2005-02-01 00:00:00

abstract：:From the roots of PICRORHIZA KURROOA a new iridoid glycoside, 6-feruloylcatalpol has been isolated, along with veronicoside and minecoside and two phenol glucosides, picein and androsin. ...

journal_title：Planta medica

authors： Stuppner H,Wagner H

更新日期：1989-10-01 00:00:00

abstract：:The present study explores the potential of nanoemulsion, a lipid drug delivery system, to improve solubility and oral absorption of Silybum marianum extract. The optimized formulation contained 40 mg/mL of commercial extract (4 % w/w) and it was composed of 2.5 g labrasol (20 %) as the oil phase, 1.5 g cremophor EL a...

journal_title：Planta medica

authors： Piazzini V,Rosseti C,Bigagli E,Luceri C,Bilia AR,Bergonzi MC

更新日期：2017-10-01 00:00:00

abstract：:Our investigations into the stability of tincture preparations of milk thistle fruit [ Silybum marianum L. Gaertn. (Asteraceae)] have led to the characterization of a new flavonolignan 4-(4-hydroxy-3-methoxyphenyl)-7-[(2 R,3 R)-3,5,7-trihydroxy-4-oxochroman-2-yl]-1-oxo-1,3,3a,4,5,7a-hexahydro-2-benzofuran-5-carboxylic...

journal_title：Planta medica

authors： MacKinnon SL,Hodder M,Craft C,Simmons-Boyce J

更新日期：2007-09-01 00:00:00

abstract：:Silybum marianum Gaertn. (Milk thistle) has been used since ancient times for the relief of liver diseases characterized by intense oxidative stress such as inflammatory liver disease and cirrhosis. As oxidative stress by hyperglycemia is involved in micro- and macrovascular complications of type 2 diabetes, our aim w...

journal_title：Planta medica

authors： Palomino OM,Gouveia NM,Ramos S,Martín MA,Goya L

更新日期：2017-01-01 00:00:00

abstract：:The flower buds of Lonicera japonica are widely used in Chinese medicine for their anti-inflammatory properties. The reason why L. japonica has potent and significant effects is that it contains various active components, especially chlorogenic acid (CGA). In the present study, we isolated a hydroxycinnamoyl-CoA quina...

journal_title：Planta medica

authors： Peng X,Li W,Wang W,Bai G

更新日期：2010-11-01 00:00:00

abstract：:Isovitexin exhibits potent antioxidant activities. In this study, the activity of nitric oxide synthase (iNOS) in lipopolysaccharide (LPS)-activated RAW264.7 macrophages after incubation with isovitexin was investigated. Isovitexin was able to reduce the production of hydrogen peroxide induced by LPS in mouse macropha...

journal_title：Planta medica

authors： Lin CM,Huang ST,Liang YC,Lin MS,Shih CM,Chang YC,Chen TY,Chen CT

更新日期：2005-08-01 00:00:00

abstract：:The in vitro antiprotozoal activity of 18 natural flavonoids has been determined against Entamoeba histolytica and Giardia lamblia. (-)-Epicatechin, (-)-epigallocatechin and kaempferol were the most active flavonoids against both protozoa. ...

journal_title：Planta medica

authors： Calzada F,Meckes M,Cedillo-Rivera R

更新日期：1999-02-01 00:00:00

abstract：:Two new 8-oxotetrahydroprotoberberine alkaloids, gusanlung A(1) and B(2), together with known isoquinoline alkaloids, berberine and jatrorrhizine, were isolated from the Chinese medicinal plant Acangelisia gusanlung H. S. Lo (Menispermaceae). Their structures were elucidated mainly by spectroscopic analysis. ...

journal_title：Planta medica

authors： Zhang JS,Chen ZL

更新日期：1991-10-01 00:00:00

abstract：:Blood fluke of the genus Schistosoma are the etiological agents of human schistosomiasis, an important neglected tropical disease that afflicts over 200 million people worldwide. The treatment for this disease relies heavily on a single drug, praziquantel. Recent reports of praziquantel resistance raise concerns about...

journal_title：Planta medica

authors： Moraes Jd,Almeida AA,Brito MR,Marques TH,Lima TC,Sousa DP,Nakano E,Mendonça RZ,Freitas RM

更新日期：2013-03-01 00:00:00

abstract：:Geraniol dehydrogenase, the specific enzyme involved in geraniol to citral TRANS (geranial) transformation, activity was monitored in various lemongrass cultivars differing in amounts and relative percentages of citral and geraniol in their essential oils. The enzyme activity had a positive and significant association...

journal_title：Planta medica

authors： Singh-Sangwan N,Sangwan RS,Luthra R,Thakur RS

更新日期：1993-04-01 00:00:00

abstract：:Extraction of PIPER RIBESOIDES Wall, furnished the new linalool derivative (+)-3,7-dimethyl-3-hydroxy-4-( P-coumaryloxy)-1,6-octadiene, the lignans (-)-hinokinin and (-)-cubebin, N-isobutyl-2 E,4 E-deca-2,4-dienamide, methyl piperate, methyl 2 E,4 E,6 E-7-phenyl-2,4,6-heptatrienoate, palmitic acid, stearic acid, and b...

journal_title：Planta medica

authors： Kijjoa A,Pinto MM,Tantisewie B,Herz W

更新日期：1989-04-01 00:00:00

abstract：:Two indole alkaloids were isolated from the culture of Aspergillus fumigatus (strain No. CY018), an endophytic fungus harboring inside the elder leaf of Cynodon dactylon. These two chemicals were identified as fumigaclavine C and fumitremorgin C. In screening the bioactivity of these two indole alkaloids, their vasore...

journal_title：Planta medica

authors： Ma HY,Song YC,Mao YY,Jiang JH,Tan RX,Luo L

更新日期：2006-04-01 00:00:00

abstract：:Endocrine activity can be demonstrated for components of the rhizome of CIMICIFUGA RACEMOSA using ovariectomized rats as experimental model. A selective reduction of the serum concentration of the pituitary luteinizing hormone (LH) takes place upon application of an extract. The active principle can be concentrated by...

journal_title：Planta medica

authors： Jarry H,Harnischfeger G

更新日期：1985-02-01 00:00:00

abstract：:The inhibitory effects of selected phenolic lichen substances were tested against a panel of methicillin- and multidrug-resistant Staphylococcus aureus. Depsidones with long alkyl chains on both of the aromatic rings were consistently active against the strains tested, comparable to or better than the level of clinica...

journal_title：Planta medica

authors： Kokubun T,Shiu WK,Gibbons S

更新日期：2007-02-01 00:00:00

abstract：:Five known abietane diterpenes, fatty acid esters of 7alpha-acyloxy-6beta-hydroxyroyleanone (1), grandidone A (2), 7alpha-acetoxy-6beta-hydroxyroyleanone (3), 6beta,7alpha-dihydroxyroyleanone (4), and coleon U (5), isolated from Plectranthus grandidentatus Gürke, were evaluated for their in vitro antiproliferative act...

journal_title：Planta medica

authors： Marques CG,Pedro M,Simões MF,Nascimento MS,Pinto MM,Rodríguez B

更新日期：2002-09-01 00:00:00

abstract：:A new activity of triterpenes and triterpenoid glycosides against phytovirus has been found. Based on the anti-TMV replication activity in vivo, 47 triterpenes and triterpenoid glycosides were screened through the leaf-disk method together with indirect ELISA. Structure-activity relationships were analyzed according t...

journal_title：Planta medica

authors： Zhang ZK,Ouyang MA,Wu ZJ,Lin QY,Xie LH

更新日期：2007-11-01 00:00:00

abstract：:Valepotriates are iridoids found in variable amounts in Valerianaceae and might be among the bioactive compounds which confer anxiolytic properties to the Valeriana species. On the other hand, unspecific cytotoxicity has also been described. Presently, however, no particular molecular target has been defined for these...

journal_title：Planta medica

authors： Bettero GM,Salles L,Rosário Figueira RM,Poser Gv,Rates SM,Noël F,Quintas LE

更新日期：2011-10-01 00:00:00

abstract：:Emodin, chrysophanol and physcion have been shown to be the major anthraquinone pigments present in the dry roots of RUMEX ABYSINICA. ...

journal_title：Planta medica

authors： Munavu RM,Mudamba LO,Ogur JA

更新日期：1984-02-01 00:00:00

abstract：:The hypoglycemic activity of olive leaf was studied. Maximum hypoglycemic activity was obtained from samples collected in the winter months, especially in February. One of the compounds responsible for this activity was oleuropeoside, which showed activity at a dose of 16 mg/kg. This compound also demonstrated antidia...

journal_title：Planta medica

authors： Gonzalez M,Zarzuelo A,Gamez MJ,Utrilla MP,Jimenez J,Osuna I

更新日期：1992-12-01 00:00:00