Abstract:
:The chemical investigation of the essential oils from the aerial organs of Bellis perennis L., the common daisy, showed that polyacetylenes were one of the dominant class of compounds. The major constituents, methyl deca-4,6-diynoate and deca-4,6-diynoic acid, and their structural analogues, deca-4,6-diyne, dimethyl octa-3,5-diyne-1,8-dioate and deca-4,6-diyne-1,10-dioic acid, were synthesised and their antimicrobial activity evaluated. Only deca-4,6-diynoic acid and deca-4,6-diyne-1,10-dioic acid showed antimicrobial activity, being the two compounds mainly effective against Gram-positive and Gram-negative bacteria, respectively. Structure-activity relationships of the tested polyacetylenes are discussed.
journal_name
Planta Medjournal_title
Planta medicaauthors
Avato P,Vitali C,Mongelli P,Tava Adoi
10.1055/s-2006-957751subject
Has Abstractpub_date
1997-12-01 00:00:00pages
503-7issue
6eissn
0032-0943issn
1439-0221journal_volume
63pub_type
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