Aged garlic extract and its constituents inhibit Cu(2+)-induced oxidative modification of low density lipoprotein.

abstract：:Cannabis (Cannabis sativa L.) is an annual herbaceous plant that belongs to the family Cannabaceae. Trans-Δ9-tetrahydrocannabinol (Δ9-THC) and cannabidiol (CBD) are the two major phytocannabinoids accounting for over 40% of the cannabis plant extracts, depending on the variety. At the University of Mississippi, differ...

journal_title：Planta medica

authors： Ibrahim EA,Gul W,Gul SW,Stamper BJ,Hadad GM,Abdel Salam RA,Ibrahim AK,Ahmed SA,Chandra S,Lata H,Radwan MM,ElSohly MA

更新日期：2018-03-01 00:00:00

abstract：:It has been known that silymarin exhibits protective activity against oxidative liver injury induced by various hepatotoxicants, but the underlying mechanism of its beneficial action remains unclear. We determined the alterations in sulfur-containing amino acid metabolism induced by silymarin in association with its e...

journal_title：Planta medica

authors： Kwon DY,Jung YS,Kim SJ,Kim YS,Choi DW,Kim YC

更新日期：2013-08-01 00:00:00

abstract：:Since the beginning of this century, Goji berries and juice are being sold as health food products in western countries and praised in advertisements and in the media for well-being and as an anti-aging remedy. The popularity of Goji products has rapidly grown over the last years thanks to efficient marketing strategi...

journal_title：Planta medica

authors： Potterat O

更新日期：2010-01-01 00:00:00

abstract：:The traditional therapeutic indications for the use of Morinda citrifolia L. (Rubiaceae) have been investigated. The lyophilised aqueous extract of roots of M. citrifolia was evaluated for analgesic and behavioural effects in mice. The extract did not exhibit any toxic effects but did show a significant, dose-related,...

journal_title：Planta medica

authors： Younos C,Rolland A,Fleurentin J,Lanhers MC,Misslin R,Mortier F

更新日期：1990-10-01 00:00:00

abstract：:Four isocedrenes (1:  - 4: ), including one new compound (2: ), were isolated from an ethanolic extract of the aerial parts of Perezia multiflora by bioactivity-guided fractionation. For compounds 1: and 3: , a revised stereochemical assignment is proposed based on molecular modeling studies using DFT-NMR calculations...

journal_title：Planta medica

authors： Bourgeade-Delmas S,André-Barrès C,Lucas J,Trinel M,Castillo Pareja D,Jullian V

更新日期：2020-11-23 00:00:00

abstract：:The nor-kaurane diterpene Atractyliretin was obtained by acid hydrolysis of Atractyloside, a toxic substance isolated from ATRACTYLIS GUMMIFERA L (Compositae). On the basis of spectral (IR, (1)H-NMR, (13)C-NMR and MS) analysis and chemical degradation its structure and stereochemistry was identified as 4. ...

journal_title：Planta medica

authors： Camarda L,Ceraulo L,Ferrugia M,Pascual C,Sprio V

更新日期：1986-10-01 00:00:00

abstract：:The roots of HAPLOPAPPUS FREEMONTII afforded in addition to the known 8-oxo-beta-cyperone two further derivatives. The structures were elucidated by highfield (1)H-NMR spectroscopy. ...

journal_title：Planta medica

authors： Jakupovic J,Boeker R,King RM

更新日期：1986-10-01 00:00:00

abstract：:Three pyrrolizidine alkaloids were isolated from Eupatorium portoricense and their structures elucidated by spectroscopic methods as (-)-viridifloryl-supinidine (amabiline), (-)-viridifloryl-heliotridine (echinatine), and C12- O-acetyl-(-)-viridifloryl-heliotridine (O(12)-acetylechinatine). ...

journal_title：Planta medica

authors： Wiedenfeld H,Guerrero R,Roeder E

更新日期：1995-08-01 00:00:00

abstract：:Thalivarmine and thalsivasine, together with the known bases thalmelatidine, thalicberine, O-methylthalicberine, thaliphylline, thalmethine, O-methylthalmethine and (-)- N-methylcanadine have been isolated from the above ground parts of THALICTRUM MINUS var. MINUS L. ...

journal_title：Planta medica

authors： Başer KH,Kinmer N

更新日期：1985-10-01 00:00:00

abstract：:The Mexican species GALPHIMIA GLAUCA (Cav.) Kuntze (Malphigiaceae) synthesises a family of sedative and anxiolytic nor-secofriedelanes, designated as galphimines. These active principles accumulate at low concentration in the aerial parts of plants from wild populations. Transformed calluses and cell suspension cultur...

journal_title：Planta medica

authors： Ortíz A,Cardoso-Taketa A,Monroy MR,Arellano J,Hernández G,Villarreal ML

更新日期：2010-03-01 00:00:00

abstract：:A lyophilised hydroalcoholic extract of Melissa officinalis L. (Lamiaceae) has been evaluated for behavioral effects in mice. According to the traditional use of M. officinalis, sedative properties have been confirmed for low doses by the decrease of behavioral parameters measured in a non-familiar environment test (s...

journal_title：Planta medica

authors： Soulimani R,Fleurentin J,Mortier F,Misslin R,Derrieu G,Pelt JM

更新日期：1991-04-01 00:00:00

abstract：:Ideally, metabolomics should deal with all the metabolites that are found within cells and biological systems. The most common technologies for metabolomics include mass spectrometry, and in most cases, hyphenated to chromatographic separations (liquid chromatography- or gas chromatography-mass spectrometry) and nucle...

journal_title：Planta medica

authors： Ge Y,Chen X,Gođevac D,Bueno PCP,Salomé Abarca LF,Jang YP,Wang M,Choi YH

更新日期：2019-08-01 00:00:00

abstract：:Rutaecarpine is an alkaloid originally isolated from the unripe fruit of Evodia rutaecarpa. Recently, rutaecarpine has been characterized to have an anti-inflammatory activity through cyclooxygenase-2 inhibition. In the present studies, the effects of rutaecarpine on liver cytochrome P450 s (P450s) and P450 s involved...

journal_title：Planta medica

authors： Lee SK,Kim NH,Lee J,Kim DH,Lee ES,Choi HG,Chang HW,Jahng Y,Jeong TC

更新日期：2004-08-01 00:00:00

abstract：:Scientific achievements in the last two decades have revolutionized the treatment and prevention of breast cancer. This is mainly because of targeted therapies and a better understanding of the relationship between estrogen, its receptor, and breast cancer. One of these discoveries is the use of synthetic selective es...

journal_title：Planta medica

authors： Oseni T,Patel R,Pyle J,Jordan VC

更新日期：2008-10-01 00:00:00

abstract：:The dietary intake of flavonoids seems to be inversely related to cardiovascular mortality. The consumption of isoflavonoids is increasing in the general population, especially due to the use of food supplements and a variety of isoflavonoid-rich foods. However, detailed studies on the vascular influence of individual...

journal_title：Planta medica

authors： Migkos T,Pourová J,Vopršalová M,Auger C,Schini-Kerth V,Mladěnka P

更新日期：2020-07-01 00:00:00

abstract：:A plant mixture containing extracts of Nigella sativa possesses blood glucose lowering effects, but the direct antidiabetic effect of Nigella sativa is not yet established. Therefore, the effect of Nigella sativa oil (NSO) on blood glucose concentrations was studied in streptozotocin diabetic rats. In addition, the ef...

journal_title：Planta medica

authors： El-Dakhakhny M,Mady N,Lembert N,Ammon HP

更新日期：2002-05-01 00:00:00

abstract：:The hydroalcoholic extract (HE) obtained from stems and leaves of Hedyosmum brasiliense, given i.p., produced significant inhibition of acetic acid-induced abdominal constriction in mice, with a mean ID50 of 12.7 mg/kg. This effect installed rapidly (0.5 h) and lasted for up to 2 h. Given orally up to 1000 mg/kg, the ...

journal_title：Planta medica

authors： Trentin AP,Santos AR,Guedes A,Pizzolatti MG,Yunes RA,Calixto JB

更新日期：1999-08-01 00:00:00

abstract：:One hundred and thirty-eight medicinal herbal drugs obtained from different suppliers were examined for microbial contaminants and for the detectability of pathogenic microorganisms. For this purpose, several microbiological standard parameters (total aerobic mesophilic count, enterobacteria, coliforms, aerobic sporef...

journal_title：Planta medica

authors： Czech E,Kneifel W,Kopp B

更新日期：2001-04-01 00:00:00

abstract：:Cell lines that were highly productive for berberine were selected by repeated cloning of small cell aggregates. The berberine content of the highest-producing cell line increased after 4 clonings to 10% dw in comparison to the 3% dw found for the parent line, and the berberine yield was about 1,500 mg/1/14 days. Ther...

journal_title：Planta medica

authors： Hara Y,Yamagata H,Morimoto T,Hiratsuka J,Yoshioka T,Fujita Y,Yamada Y

更新日期：1989-04-01 00:00:00

abstract：:Targeted isolation based on a combination of NMR and HPLC-PDA-MS of a dichloromethane extract of Thymus vulgaris Varico 3 aerial parts afforded one new p-cymene dimer, 6,3',4'-trihydroxy-5,5'-diisopropyl-2,2'-dimethylbiphenyl (1: ), together with two known p-cymene derivatives (2: and 3: ), as well as five known compo...

journal_title：Planta medica

authors： Stefanis I,Hadjipavlou-Litina D,Bilia AR,Karioti A

更新日期：2019-08-01 00:00:00

abstract：:Leaves of Ligustrum vulgare (common privet) have been used for treatment of oropharyngeal inflammations or as antirheumatic, diuretic, and hypotensive agents in folk medicine in southern Europe. Taking into account that neutrophils are involved in the inflammation, the aim of the study was to determine the effect of a...

journal_title：Planta medica

authors： Czerwińska ME,Granica S,Kiss AK

更新日期：2013-07-01 00:00:00

abstract：:The aim of this study was to investigate the protective effect of (S)-bakuchiol isolated from the seed of Psoralea corylifolia, on liver injury. Primary rat hepatocyte intoxication was induced by tert-butyl hydroperoxide (tBH), carbon tetrachloride (CCl4) or D-galactosamine (D-GalN). Liver injury was induced by either...

journal_title：Planta medica

authors： Park EJ,Zhao YZ,Kim YC,Sohn DH

更新日期：2005-06-01 00:00:00

abstract：:Continued examination of the stem bark of Newbouldia laevis afforded three minor phenylethanoid glycosides, designated as newbouldiosides D - F. Their structures were elucidated by spectroscopic methods as β-(3,4-dihydroxyphenyl)ethyl 5-O-syringoyl-β-D-apiofuranosyloxy-(1 → 2)-O-[α-L-rhamnopyranosyl-(1 → 3)]-6-O-E-sin...

journal_title：Planta medica

authors： Kolodziej H

更新日期：2020-11-06 00:00:00

abstract：:It has been reported that cedarwood oil has sedative effects when inhaled. In this study, we evaluated sedative effects of inhaled cedrol, which is a major component of cedarwood oil. Accumulative spontaneous motor activity was significantly decreased in the cedrol-exposed Wistar rats. Similar results were confirmed i...

journal_title：Planta medica

authors： Kagawa D,Jokura H,Ochiai R,Tokimitsu I,Tsubone H

更新日期：2003-07-01 00:00:00

abstract：:From stem barks of Isolona guesquiereina three known bisbenzylisoquinolines were isolated and identified as (-)-curine, chondrofoline and isochondodendrine. Structures were established mainly on the basis of comparison of their physical and spectral data with published data for them and their methylated derivatives. C...

journal_title：Planta medica

authors： Mambu L,Martin MT,Razafimahefa D,Ramanitrahasimbola D,Rasoanaivo P,Frappier F

更新日期：2000-08-01 00:00:00

abstract：:Phytochemical investigations of the stem of Kadsura heteroclita (Roxb) Craib (Schizandraceae) resulted in the isolation and structure elucidation of six new triterpenoidal compounds named heteroclitalactones A-E (1-5) as well as heteroclic acid (6) and heteroclitalactone F (7), which was isolated for the first time fr...

journal_title：Planta medica

authors： Wang W,Liu J,Han J,Xu Z,Liu R,Liu P,Wang W,Ma X,Guan S,Guo D

更新日期：2006-04-01 00:00:00

abstract：:Treatment of 28-hydroxyolean-12-enes with N-bromosuccinimide (NBS) in acetonitrile at room temperature afforded 12 alpha-bromooleanan-13beta, 28-epoxides in high yield. This reaction resulted in the formation of olean-9 (11), 12-diene-18alpha, 29-epoxides from 29-hydroxy isomers but recovered only starting materials f...

journal_title：Planta medica

authors： Woo WS,Kang SS,Jew SS

更新日期：1985-12-01 00:00:00

abstract：:Bisbenzylisoquinoline alkaloids are known to affect immune responses as well as inflammatory responses, and have been used for the treatment of inflammatory symptoms in China. This study is aimed at elucidating the inhibitory effects of two alkaloids, fangchinoline and isotetrandrine, on the induction of the proinflam...

journal_title：Planta medica

authors： Onai N,Tsunokawa Y,Suda M,Watanabe N,Nakamura K,Sugimoto Y,Kobayashi Y

更新日期：1995-12-01 00:00:00

abstract：:We report a sensitive method for the estimation of quinine (Qn), cinchonine (Cn), and cinchonidine (Cnd) and a new method based on fluorescence enhancement and detection and quantification of quinidine (Qnd) from Cinchona stem bark and its formulations, using HPTLC. Standard solutions of Qn, Qnd, Cn, and Cnd were appl...

journal_title：Planta medica

authors： Ravishankara MN,Shrivastava N,Padh H,Rajani M

更新日期：2001-04-01 00:00:00

abstract：:Croton caudatus is an important species in Dai folk medicine. Some other Croton species, in particular, C. kongensis, C. cascarilloides, C. crassifolius, C. lachnocarpus and C. olivaceus are often marketed as C. caudatus, and thus, the therapeutic effects of C. caudatus are not achieved. The respective morphological f...

journal_title：Planta medica

authors： Xue HG,Zhou SD,He XJ,Yu Y

更新日期：2007-06-01 00:00:00