Flow Cytometric Analysis of Cellular Berberine Contents in High- and Low-Producing Cell Lines of Coptis japonica Obtained by Repeated Selection.

abstract：:The known alkaloids (+/-)-stylopine, (+/-)-sinactine, protopine, (+)-bulbocapnine, (-)-domesticine, (+)-corydine and (+)-isoboldine were found in the mixture of alkaloids from Corydalis marschalliana (Papaveraceae), growing in Bulgaria. The alkaloids dehydronantenine, (+)-nantenine and oxonantenine were isolated for t...

journal_title：Planta medica

authors： Kiryakov HG,Iskrenova E,Kuzmanov B,Evstatieva L

更新日期：1981-03-01 00:00:00

abstract：:The effect of extracts of MOMORDICA CHARANTIA L. fruits on glucose metabolism and glucose uptake was investigated. The fruit of momordica, at all ripening stages, was found to contain two inhibitory compounds: one against hexokinase activity and the other against glucose uptake by rat intestinal fragments. Both inhibi...

journal_title：Planta medica

authors： Meir P,Yaniv Z

更新日期：1985-02-01 00:00:00

abstract：:The aim of this study was to investigate the effect of demethylbellidifolin (DMB), a major xanthone compound of Swertia davidi franch, on nitroglycerin (NTG) tolerance. In the in vivo portion of the study, pretreatment of Sprague-Dawley rats with NTG (10 mg/kg) for 8 days caused tolerance to the depressor effect of NT...

journal_title：Planta medica

authors： Shi RZ,Li XH,Jia SJ,Fu QM,Chen YR,Chen J,Chen A,Li SX,Tan GS,Li YJ,Zhang GG

更新日期：2009-11-01 00:00:00

abstract：:P57AS3 (P57), an oxypregnane steroidal glycoside, is known to be responsible for the appetite suppressing activity of HOODIA GORDONII, a dietary supplement used for weight loss. In this study, bioavailability, pharmacokinetics, and tissue distribution of P57 were determined in CD1 female mice after administration of a...

journal_title：Planta medica

authors： Madgula VL,Ashfaq MK,Wang YH,Avula B,Khan IA,Walker LA,Khan SI

更新日期：2010-10-01 00:00:00

abstract：:Leaves and stem barks of S. scheffleri Gilg afforded eight dihydroindole alkaloids. Four tertiary monomers (O-methyl Na-acetylstrychnosplendine, Na-acetylstrychnosplendine, strychnobrasiline and strychnofendlerine) have been isolated from leaf material while stem barks yielded one tertiary monomer (desacetylisoretulin...

journal_title：Planta medica

authors： Caprasse M,Angenot L

更新日期：1981-08-01 00:00:00

abstract：:A phytochemical study of the whole plant of TEPHROSIA HAMILTONII afforded a new flavonoid, characterised as 5, 7-dimethoxy-8-(2, 3-epoxy-3-methylbutyl)-flavanone, along with other known compounds. ...

journal_title：Planta medica

authors： Falak AH,Shoeb A

更新日期：1987-04-01 00:00:00

abstract：:Four new iridoids viz., plumeridoids A, B, and C and epiplumeridoid C were isolated from the stem bark of Plumeria rubra Linn. together with twenty-four known compounds viz., 1-( P-hydroxyphenyl)propan-1-one, isoplumericin, plumericin, dihydroplumericin, allamcin, fulvoplumerin, allamandin, plumieride, P- E-coumaric a...

journal_title：Planta medica

authors： Kuigoua GM,Kouam SF,Ngadjui BT,Schulz B,Green IR,Choudhary MI,Krohn K

更新日期：2010-04-01 00:00:00

abstract：:Three new dammar-type triterpenoid caffeates (1-3) were isolated from the stalks of Celastrus rosthornianus Loes. Their structures were established through various spectral studies as 3beta,20(S),24(S)-trihydroxyldammar-25-ene 3-caffeate (1), 3beta,20(S),24(R)-trihydroxyldammar-25-ene 3-caffeate (2) and 3beta,20(S),25...

journal_title：Planta medica

authors： Wang KW,Sun CR,Wu XD,Pan YJ

更新日期：2006-03-01 00:00:00

abstract：:A new acylated flavonoid, quercetin 3- O-alpha- L-(5"- O-acetyl)-arabinofuranoside ( 1), along with six known flavonoids ( 2 - 7) were isolated from the aerial parts of Rodgersia podophylla. The new flavonoid 1 exhibited 50.1 % hepatoprotective activity at a concentration of 100 microM, and the three known compounds 3...

journal_title：Planta medica

authors： Chin YW,Lim SW,Kim YC,Choi SZ,Lee KR,Kim J

更新日期：2004-06-01 00:00:00

abstract：:A new strain of Claviceps was isolated from a blokked mutant of Claviceps purpurea. This strain accumulates substantial amounts of clavine alkaloids (2 g/l). The alkaloid fraction is composed of chanoclavine-I ( approximately 10%) and a mixture of agroclavine/elymoclavine (90%). Most suitable for alkaloid production i...

journal_title：Planta medica

authors： Schumann B,Erge D,Maier W,Gröger D

更新日期：1982-05-01 00:00:00

abstract：:Solasodine--a steroid present in the mucilaginous exotesta of the seed in Solanum viarum Dunal (syn. S. khasianum var. chatterjeeanum) is a major source of steroidal raw material. Evidence for the site of solasodine synthesis was sought through reciprocal grafts involving steroid-bearing S. viarum (both diploid and au...

journal_title：Planta medica

authors： Srinivas M,Krishnan R

更新日期：1996-08-01 00:00:00

abstract：:Ischemic preconditioning, which is mediated by cell signaling molecules, protects the heart from ischemia-reperfusion injury by limiting the infarct size. Oleuropein, the main polyphenolic constituent of olives, reduced the infarct size in normal and cholesterol-fed rabbits when it was administered at a nutritional do...

journal_title：Planta medica

authors： Andreadou I,Benaki D,Efentakis P,Bibli SI,Milioni AI,Papachristodoulou A,Zoga A,Skaltsounis AL,Mikros E,Iliodromitis EK

更新日期：2015-06-01 00:00:00

abstract：:The leaves of Myrcia ovata, popularly known as "laranjinha do mato", are frequently used as an infusion in folk medicine. The essential oil obtained from these leaves is rich in citral, a mixture of neral and geranial isomers, known for its analgesic effect. Male Swiss mice (20-22 g) were tested in models of acute pai...

journal_title：Planta medica

authors： Dos Santos GC,Gomes GA,Gonçalves GM,de Sousa LM,Santiago GM,de Carvalho MG,Marinho BG

更新日期：2014-11-01 00:00:00

abstract：:Stabilization of growth factors in a wound environment is critical to the wound healing process. Here we report on the stabilization of key growth factors by a unique plant cell wall biomaterial. MicroSheets are clear cell wall fragments isolated from the non-living water storage cells in the pulp or inner gel of Aloe...

journal_title：Planta medica

authors： Ni Y,Turner D,Yates K,Tizard I

更新日期：2007-10-01 00:00:00

abstract：:We report the effects of aqueous extracts of the microalgae Dunaliella tertiolecta Butcher (Chlorophyceae) and Phaeodactylum tricornutum Bohlin (Bacillariophyceae) on oxotremorin-induced cholinergic symptoms, amphetamine-induced hypermotility, pentylenetetrazole-induced convulsions, and Rota-rod test performance. Both...

journal_title：Planta medica

authors： Laguna MR,Villar RM,Cadavid I,Calleja JM

更新日期：1990-04-01 00:00:00

abstract：:This Paper describes an improved HPLC method for the determination of pentacyclic oxindole alkaloids in Uncaria tomentosa (Cat's Claw). Six of the isomeric compounds could be baseline separated at room temperature within less than 30 min by using 3 microm C-18 column material and a mobile phase consisting of 10 mM pho...

journal_title：Planta medica

authors： Ganzera M,Muhammad I,Khan RA,Khan IA

更新日期：2001-07-01 00:00:00

abstract：:Two new C(18) dibenzocyclooctadiene lignans named heteroclitalignans A and B (1 and 3), one new C(19) homolignan named heteroclitalignan C(4) and one new natural product named heteroclitalignan D(2), together with the four known lignans kadsurarin (5), kadsulignan E (6), d-epigalbacin, and meso-dihydroguaiaretic acid ...

journal_title：Planta medica

authors： Wang W,Liu J,Liu R,Xu Z,Yang M,Wang W,Liu P,Sabia G,Wang X,Guo D

更新日期：2006-02-01 00:00:00

abstract：:The phenylpropanoid dibenzylbutyrolactone lignan arctigenin, a key component found in Arctium lappa, or burdock, has been reported with a variety of therapeutic effects including anticancer, anti-inflammation, and antivirus effects. Using LC/MS/MS, three novel metabolites of arctigenin, namely, arctigenic acid, arctig...

journal_title：Planta medica

authors： Gao Q,Zhang Y,Wo S,Zuo Z

更新日期：2013-04-01 00:00:00

abstract：:Dioscoretine isolated from the aqueous fraction of the methanol extract of Dioscorea dumetorum tubers when administered intra-peritoneally to normal and alloxan diabetic rabbits produces significant hypoglycaemic effects at a dose of 20 mg/kg. The fasting blood sugar in normoglycaemic rabbits was reduced from 112 mg/1...

journal_title：Planta medica

authors： Iwu MM,Okunji CO,Ohiaeri GO,Akah P,Corley D,Tempesta MS

更新日期：1990-06-01 00:00:00

abstract：:The chloroform extract of the stems of Encelia ventorum yielded a new benzopyranbenzofuran dimer. The structure was assigned from (1)H-NMR and MS data as 4[2-(5-acetyl-6-hydroxybenzofuranyl)]-2-[6(7-methoxy-2, 2-dimethylbenzo-1 -pyranyl)]-pentan-2-ol. ...

journal_title：Planta medica

authors： Proksch P,Aregullin M,Rodriguez E

更新日期：1983-04-01 00:00:00

abstract：:Bioassay-directed fractionation of the chloroform-methanol (1:1) extract of Dodonaea viscosa (L.) Jacq. (Sapindaceae) resulted in the isolation of four active spasmolytic principles: sakuranetin (1), 6-hydroxykaempferyl 3,7-dimethyl ether (2) hautrivaic acid (3), and ent-15, 16-epoxy-9 alpha H-labda-13(16)14-diene-3 b...

journal_title：Planta medica

authors： Rojas A,Cruz S,Ponce-Monter H,Mata R

更新日期：1996-04-01 00:00:00

abstract：:Activator protein 1 (AP-1) is a transcription factor which plays a critical role in inflammation and carcinogenesis. The present study was conducted to investigate the effect of berberine, an isoquinoline alkaloid present in plants of the genera Berberis and Coptis, on the activity of AP-1 using a reporter gene assay ...

journal_title：Planta medica

authors： Fukuda K,Hibiya Y,Mutoh M,Koshiji M,Akao S,Fujiwara H

更新日期：1999-05-01 00:00:00

abstract：:We have previously reported that saiboku-to, an Oriental herbal remedy composed of a mixture of 10 different herbal extracts, possesses anti-histamine release effect on mast cells in rats. This effect may be due mainly to the extract of the bark of Magnolia obovata (M. obovata), a constituent herb of saiboku-to. In th...

journal_title：Planta medica

authors： Ikarashi Y,Yuzurihara M,Sakakibara I,Nakai Y,Hattori N,Maruyama Y

更新日期：2001-11-01 00:00:00

abstract：:Metabolic fingerprinting techniques have received a lot of attention in recent years and the annual amount of publications in this field has increased significantly over the past decade. This increase in publications is due to improvements in the analytical performance, most notably in the field of NMR and MS analysis...

journal_title：Planta medica

authors： van der Kooy F,Maltese F,Choi YH,Kim HK,Verpoorte R

更新日期：2009-06-01 00:00:00

abstract：:DNA technology provides a powerful tool to complement chemical analyses for authentication of Chinese medicinal plants and to ensure that herbal materials are not contaminated with ineffective or potentially harmful substitutes or adulterants. In the last two decades molecular biotechnology has provided sophisticated ...

journal_title：Planta medica

authors： Heubl G

更新日期：2010-12-01 00:00:00

abstract：:Plectranthus barbatus Andr. is one of the most important species of the genus Plectranthus L' Herit. (Lamiaceae), with a wide variety of traditional medicinal uses in Hindu and Ayurvedic traditional medicine as well as in the folk medicine of Brazil, tropical Africa and China. The plant has therefore been an attractiv...

journal_title：Planta medica

authors： Alasbahi RH,Melzig MF

更新日期：2010-05-01 00:00:00

abstract：:The isoflavonoids found in soy have attracted great interest as dietary phytoestrogens that might be effective for postmenopausal hormone replacement therapy. Special attention has been devoted to the hormonal effects of various isoflavonoids, like genistein (GEN) and daidzein's (DAID) potent metabolite, equol (EQ). H...

journal_title：Planta medica

authors： Tezval M,Sehmisch S,Seidlová-Wuttke D,Rack T,Kolios L,Wuttke W,Stuermer KM,Stuermer EK

更新日期：2010-02-01 00:00:00

abstract：:The acylphloroglucinol derivative hyperforin is a major constituent of St. John's wort extracts ( Hypericum perforatum L.), which has been demonstrated to contribute to the antidepressant action of this herbal drug. In previous investigations we observed that hyperforin causes a rapid stimulation of intracellular calc...

journal_title：Planta medica

authors： Schrattenholz A,Schroer K,Chatterjee SS,Koch E

更新日期：2004-04-01 00:00:00

abstract：:Three new azaphilones, chaetomugilin S (1), 7,5'-bis-epi-chaetoviridin A (2), and 7-epi-chaetoviridin E (3), and two new chlorinated phenolic glycosides, globosumoside A (4) and globosumoside B (5), were isolated from the crude extract of the fungal strain Chaetomium elatum No. 89-1-3-1. Their structures were determin...

journal_title：Planta medica

authors： Chen GD,Li YJ,Gao H,Chen Y,Li XX,Li J,Guo LD,Cen YZ,Yao XS

更新日期：2012-10-01 00:00:00

abstract：:Andrographis paniculata contains four major active diterpenoids, including andrographolide (1), 14-deoxy-11, 12-didehydroandrographolide (2), neoandrographolide (3), and 14-deoxyandrographolide (4), which exhibit differences in types and/or degrees of their pharmacological activity. Previous pharmacokinetic studies in...

journal_title：Planta medica

authors： Pholphana N,Panomvana D,Rangkadilok N,Suriyo T,Ungtrakul T,Pongpun W,Thaeopattha S,Satayavivad J

更新日期：2016-01-01 00:00:00