Abstract:
:The traditional therapeutic indications for the use of Morinda citrifolia L. (Rubiaceae) have been investigated. The lyophilised aqueous extract of roots of M. citrifolia was evaluated for analgesic and behavioural effects in mice. The extract did not exhibit any toxic effects but did show a significant, dose-related, central analgesic activity in the writhing and hotplate tests; this effect was confirmed by the antagonistic action of naloxone. Furthermore, administration of M. citrifolia extract at high dosages decreased all behavioural parameters in the two compartment test, the light/dark choice situation test, and the staircase test; together with the induced sleeping time, these results are suggestive of sedative properties.
journal_name
Planta Medjournal_title
Planta medicaauthors
Younos C,Rolland A,Fleurentin J,Lanhers MC,Misslin R,Mortier Fdoi
10.1055/s-2006-961004subject
Has Abstractpub_date
1990-10-01 00:00:00pages
430-4issue
5eissn
0032-0943issn
1439-0221journal_volume
56pub_type
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