Effects of magnesium lithospermate B and its analogues on Ca(2+) homeostasis in cultured rat thoracic aorta vascular smooth muscle cells.

abstract：:Ent-11alpha-hydroxy-16-kauren-15-one (1) induced apoptosis in a human leukemia cell line (HL-60 cells), however, the apoptosis-inducing properties of 1 and its related compounds remain to be proved. We examined the involvement of caspases, a family of cysteine aspartic proteases, which play a central role in induction...

journal_title：Planta medica

authors： Nagashima F,Kondoh M,Kawase M,Simizu S,Osada H,Fujii M,Watanabe Y,Sato M,Asakawa Y

更新日期：2003-04-01 00:00:00

abstract：:Fresh Nagami kumquats (Fortunella margarita) were subjected to hydrodistillation using a Clevenger-type apparatus to obtain volatile oil. The chemical composition of the volatile oil was analyzed by GC-MS using Rtx-5 Sil MS and DB Wax columns. A total of 25 volatile compounds were identified by mass spectra, retention...

journal_title：Planta medica

authors： Jayaprakasha GK,Murthy KN,Demarais R,Patil BS

更新日期：2012-06-01 00:00:00

abstract：:In the course of our screening program for acyl-CoA : cholesterol acyltransferase (ACAT) inhibitors from Korean herbal medicines, ACAT inhibitors were isolated from the hairy roots of Panax ginseng (Araliaceae) and identified as panaxynol, panaxydol, panaxydiol, and panaxytriol. These active compounds inhibit rat live...

journal_title：Planta medica

authors： Kwon BM,Ro SH,Kim MK,Nam JY,Jung HJ,Lee IR,Kim YK,Bok SH

更新日期：1997-12-01 00:00:00

abstract：:From an extract of the whole plant of Ligularia virgaurea ssp. oligocephala, three new eremophilane sesquiterpene lactones, 10alpha-hydroxy-1-oxoeremophila-7(11),8(9)-dien-12,8-olide (1), 6alpha,10alpha-dihydroxy-1-oxoeremophila-7(11),8(9)-dien-12,8-olide (2), 6beta,10beta-dihydroxyeremophila-7(11),8(9)-dien-12,8-olid...

journal_title：Planta medica

authors： Wu QX,Shi YP,Yang L

更新日期：2004-05-01 00:00:00

abstract：:A procedure is described for the extraction of both anthraquinones and alkaloids from tissue culture material of CINCHONA species. Using this extraction method, it is possible to quantitatively determine the two groups of secondary metabolites produced in CINCHONA tissue cultures. ...

journal_title：Planta medica

authors： Wijnsma R,van Vliet TB,Harkes PA,van Groningen HJ,van der Heijden R,Verpoorte R,Svendsen AB

更新日期：1987-02-01 00:00:00

abstract：:Since the beginning of this century, Goji berries and juice are being sold as health food products in western countries and praised in advertisements and in the media for well-being and as an anti-aging remedy. The popularity of Goji products has rapidly grown over the last years thanks to efficient marketing strategi...

journal_title：Planta medica

authors： Potterat O

更新日期：2010-01-01 00:00:00

abstract：:Cnidicin (1) and five related coumarins were isolated from the root extract of Angelica koreana (Umbelliferae) as active principles responsible for the inhibitory effect on the degranulation process of cultured mast cells. Cnidicin (1) demonstrated a significant inhibition upon the release of beta-hexosaminidase from ...

journal_title：Planta medica

authors： Ryu SY,Kou NY,Choi HS,Ryu H,Kim TS,Kim KM

更新日期：2001-03-01 00:00:00

abstract：:From the fresh, undried, and uncrushed leaves of NERIUM OLEANDER a new triterpenoid, kanerocin, has been isolated along with known ursolic and oleanolic acids and its structure established through chemical and spectroscopic methods as 3alpha-hydroxy-urs-18,20-dien-28-oic acid. ...

journal_title：Planta medica

authors： Siddiqui S,Siddiqui BS,Begum S,Hafeez F

更新日期：1989-06-01 00:00:00

abstract：:Two indole alkaloids were isolated from the culture of Aspergillus fumigatus (strain No. CY018), an endophytic fungus harboring inside the elder leaf of Cynodon dactylon. These two chemicals were identified as fumigaclavine C and fumitremorgin C. In screening the bioactivity of these two indole alkaloids, their vasore...

journal_title：Planta medica

authors： Ma HY,Song YC,Mao YY,Jiang JH,Tan RX,Luo L

更新日期：2006-04-01 00:00:00

abstract：:The pharmacokinetics of huperzine A in dogs after single intravenous and oral administrations was investigated. Concentrations of huperzine A were determined by a validated liquid chromatography-tandem mass spectrometry (LC-MS/MS) method. Pharmacokinetic parameters were calculated by non-compartmental methods. After s...

journal_title：Planta medica

authors： Chu D,Liu W,Li Y,Li P,Gu J,Liu K

更新日期：2006-05-01 00:00:00

abstract：:The investigation of the roots and aerial parts of EUPATORIUM CANNABIUM afforded, in addition to the sesquiterpene lactones eupatolide, eupatoriopicrin, and eucannabinolide isolated previously, eight further lactones, three of which are new. Furthermore, in addition to known compounds, a new clerodane derivative and t...

journal_title：Planta medica

authors： Zdero C,Bohlmann F

更新日期：1987-04-01 00:00:00

abstract：:The chemical composition of the three essential oils obtained by steam distillation of the mastic gum, leaves and twigs of Pistacia lentiscus var. chia, was studied by GC/MS. Sixty nine constituents were identified from the oils. alpha-Pinene, myrcene, trans-caryophyllene and germacrene D were found to be the major co...

journal_title：Planta medica

authors： Magiatis P,Melliou E,Skaltsounis AL,Chinou IB,Mitaku S

更新日期：1999-12-01 00:00:00

abstract：:Turmeric has been extensively utilized in Indian and Chinese medicine for its immune-modulatory properties. Dendritic cells (DCs) are antigen-presenting cells specialized to initiate and regulate immunity. The ability of DCs to initiate immunity is linked to their activation status. The effects of turmeric on human DC...

journal_title：Planta medica

authors： Krasovsky J,Chang DH,Deng G,Yeung S,Lee M,Leung PC,Cunningham-Rundles S,Cassileth B,Dhodapkar MV

更新日期：2009-03-01 00:00:00

abstract：:Phytochemical analysis of the leaves of BOLDOA PURPURASCENS Cav. led to isolation of four flavone glycosides, three of which are new compounds. Their structures have been determined by mass spectrometry and by 1 D and 2 D NMR analysis, i. e., 4',5-dihydroxy-6,7-methylenedioxyflavonol 3- O-alpha- L-rhamnopyranosyl-(1--...

journal_title：Planta medica

authors： Mosquera DM,Kilonda A,Toppet S,Compernolle F,Dehaen W,François IE,Cammue BP,Apers S,Pieters L,Cuéllar AC

更新日期：2008-10-01 00:00:00

abstract：:The inhibitory effect of flavonoids and phenolic acids, which could be transformed from flavonoids by human intestinal microflora, on the growth of Helicobacter pylori (HP) was investigated. Ponciretin, hesperetin, naringenin and diosmetin were active against HP. Among them, ponciretin was the most potent and its MIC ...

journal_title：Planta medica

authors： Bae EA,Han MJ,Kim DH

更新日期：1999-06-01 00:00:00

abstract：:Myrrh is the oleo-gum resin of mainly Commiphora molmol and as a powdered substance, one compound in the traditional medicinal product Myrrhinil-Intest®, which has been used for the treatment of unspecific, inflammatory intestinal disorders. The aim of the present study was to evaluate the antispasmodic effect of myrr...

journal_title：Planta medica

authors： Vissiennon C,Goos KH,Goos O,Nieber K

更新日期：2015-01-01 00:00:00

abstract：:Ten new polyhydroxyolean-12-ene pentacyclic triterpenoidal saponins, named rogchaponins 1-10, were isolated from the methanolic extract of the roots of Camellia sinensis by a series of chromatographic methods (silica gel flash column and C18 MPLC followed by C18 HPLC). Their structures were established by 1D and 2D-NM...

journal_title：Planta medica

authors： Varughese T,Manir MM,Rahaman M,Kim JK,Lee BG,Moon SS

更新日期：2011-12-01 00:00:00

abstract：:Sigmoidin A (SGN) is a prenylated flavanone derivative of eriodictyol (ERD) with reported moderate antioxidant, antimicrobial and anti-inflammatory activity. Since ERD and other structurally similar antioxidant phenolic compounds have been shown to induce prooxidative macromolecular damage and cytotoxicity in cancer c...

journal_title：Planta medica

authors： Habtemariam S,Dagne E

更新日期：2010-04-01 00:00:00

abstract：:Juniperus (Cupressaceae, Pinales) plants are widely distributed in the Qinghai-Tibet Plateau of China. The leaves and twigs of at least 8 Juniperus species (J. pingii, J. pingii var. wilsonii, J. squamata, J. recurva var. coxii, J. saltuaria, J. indica, J. tibetica and J. convallium var. microsperma) have been used as...

journal_title：Planta medica

authors： Yang YT,De J,Fu ZL,Wang XL,Chen DF,Xie H,Lu Y

更新日期：2020-11-01 00:00:00

abstract：:The effects of four fractions, a hexane fraction, an ethyl acetate fraction, an N-butanol fraction and a water fraction, from a water extract of Herba Visci were investigated to find the fraction, in IN VITRO experiments, with the greatest ability to inhibit the formation of osteoclast-like multinucleated cells from m...

journal_title：Planta medica

authors： Yin J,Han N,Xu X,Liu Z,Zhang B,Kadota S

更新日期：2008-02-01 00:00:00

abstract：:Three new vermistatin derivatives, 6-demethylpenisimplicissin (1), 5'-hydroxypenisimplicissin (2), and 2''-epihydroxydihydrovermistatin (3), along with five known vermistatin analogues, methoxyvermistatin (4), vermistatin (5), 6-demethylvermistatin (6), hydroxyvermistatin (7), and penisimplicissin (8), were isolated f...

journal_title：Planta medica

authors： Liu Y,Xia G,Li H,Ma L,Ding B,Lu Y,He L,Xia X,She Z

更新日期：2014-07-01 00:00:00

abstract：:The endophytic microbiome in medicinal plants is rich and diverse, but few studies have followed the endophytic microbiome of medicinal plants in different tissues with their growth. In this study, we examined the endophytic bacterial and fungal community structures associated with both the stem and root compartments ...

journal_title：Planta medica

authors： Chen S,Dai J,Song X,Jiang X,Zhao Q,Sun C,Chen C,Chen N,Han B

更新日期：2020-09-01 00:00:00

abstract：:A new BIS-1-oxaquinolizidine alkaloid, 9'- EPI-3 β,3' β-dimethylxestospongin C (2), and three known related analogues have been isolated from the Hainan sponge Neopetrosia exigua. ...

journal_title：Planta medica

authors： Li Y,Qin S,Guo YW,Gu YC,van Soest RW

更新日期：2011-01-01 00:00:00

abstract：:A sensitive and rapid liquid chromatography-mass spectrometric method for the determination of ophiopogonin D in rat plasma was developed and validated. Chromatographic separation was performed on a C (18) column using a step gradient program with the mobile phase of 0.5 mmol/L ammonium chloride solution and acetonitr...

journal_title：Planta medica

authors： Xia CH,Sun JG,Hao HP,Wang GJ,Yan B,Gu SH,Zheng CN,Shang LL,Roberts MS

更新日期：2008-12-01 00:00:00

abstract：:Panaxytriol, a polyacetylenic compound, isolated from red ginseng (Panax ginseng C.A. Meyer), was studied to determine its effects on the growth and cell cycle of tumor cell lines. The compound showed both significant cytotoxicity and inhibition of DNA syntheses in various tumor cells tested. For P388D1, a mouse lymph...

journal_title：Planta medica

authors： Kim JY,Lee KW,Kim SH,Wee JJ,Kim YS,Lee HJ

更新日期：2002-02-01 00:00:00

abstract：:Five compounds representative of major structural classes of lichen polyketides, VIZ. (+)-usnic (1), salazinic (2), vulpinic (3), gyrophoric (4), and evernic acids (5), were investigated for their ability to affect cell proliferation or wound healing, two functional targets of relevance for research on cancer or tissu...

journal_title：Planta medica

authors： Burlando B,Ranzato E,Volante A,Appendino G,Pollastro F,Verotta L

更新日期：2009-05-01 00:00:00

abstract：:Astilbin, a flavonoid compound, was isolated from the rhizome of Smilax glabra Roxb. This study was conducted to investigate the efficacy of astilbin on experimental diabetic nephropathy (DN) in vivo and in vitro and its possible mechanisms. Astilbin was added in high glucose stimulated HK-2 cells, streptozotocin-indu...

journal_title：Planta medica

authors： Li GS,Jiang WL,Yue XD,Qu GW,Tian JW,Wu J,Fu FH

更新日期：2009-11-01 00:00:00

abstract：:Citral, 3,7-dimethyl-2,6-octadien-1-al, a key component of the lemon-scented essential oils extracted from several herbal plants such as lemon grass (Cymbopogon citratus), melissa (Melissa officinalis), verbena (Verbena officinalis) is used as a food additive and as a fragrance in cosmetics. In this study, we investig...

journal_title：Planta medica

authors： Dudai N,Weinstein Y,Krup M,Rabinski T,Ofir R

更新日期：2005-05-01 00:00:00

abstract：:Epilobium sp. are commonly used in traditional medicine in the treatment of early stages of benign prostatic hyperplasia and inflammation. It is suggested that a dominating constituent, oenothein B, is responsible for the extracts therapeutic effects. Several bioactivities were established for extracts and oenothein B...

journal_title：Planta medica

authors： Piwowarski JP,Bobrowska-Korczak B,Stanisławska I,Bielecki W,Wrzesien R,Granica S,Krupa K,Kiss AK

更新日期：2017-10-01 00:00:00

abstract：:Mammea-type coumarins are a particular type of secondary metabolites biosynthesized by the tropical rainforest tree Calophyllum Brasiliense, which is distributed from South America to Mexico. Particularly, mammea A/BA and A/BB (alone or as a mixture) possess biological properties such as cytotoxic and antitumoral acti...

journal_title：Planta medica

authors： Gómez-Verjan JC,Rivero-Segura NA,Estrella-Parra E,Rincón-Heredia R,Madariaga-Mazón A,Flores-Soto E,González-Meljem M,Cerbón M,Reyes-Chilpa R

更新日期：2019-01-01 00:00:00