Cnidicin, a coumarin, from the root of Angelica koreana, inhibits the degranulation of mast cell and the NO generation in RAW 264.7 cells.

abstract：:A gas-chromatographical method is described on which seven pyrrolizidine alkaloids (Fuchsisenecionine, Senecionine, Senecivernine, Senkirkine, Retrorsine, O (7)-Angelylheliotridine and Heliotrine) are determinated in a qualitative way and their ratio of concentration in Senecio fuchsii, vernalis, inaequidens and ovire...

journal_title：Planta medica

authors： Wiedenfeld H,Pastewka U,Stengl P,Röder E

更新日期：1981-02-01 00:00:00

abstract：:From the fresh rhizomes of Tamus communis five phenanthrenes (1 - 5) were isolated under the guidance of cytotoxic assays in HeLa cells. The compounds were obtained from the highly active CHCl (3) fraction of the MeOH extract by using multistep chromatographic purifications, including VLC, preparative TLC, HPLC and ge...

journal_title：Planta medica

authors： Réthy B,Kovács A,Zupkó I,Forgo P,Vasas A,Falkay G,Hohmann J

更新日期：2006-06-01 00:00:00

abstract：:Malaria treatment and control have become increasingly difficult because of the spread of drug-resistant strains of Plasmodium falciparum and Plasmodium vivax. Thus, there is a continuous need to develop new combination therapies such as artemisinin-based combination therapies (ACTs) to contrast the emergence of resis...

journal_title：Planta medica

authors： Sannella AR,Karioti A,Orsini S,Scalone A,Gradoni L,Messori L,Severini C,Bilia AR

更新日期：2019-08-01 00:00:00

abstract：:The present study is aimed at evaluating the effects of luteolin on the scratching behavior associated with an allergic cutaneous reaction in mice. Elicitation of passive cutaneous anaphylaxis, and intradermal injections of compound 48/80, histamine or serotonin induced scratching behavior in ICR mice. Models of irrit...

journal_title：Planta medica

authors： Baolin L,Weiwei W,Ning T

更新日期：2005-05-01 00:00:00

abstract：:Stellera chamaejasme, also known as "Langdu", has been traditionally used for the management of skin-related diseases such as psoriasis and skin ulcers. The aim of this study was to determine whether S. chamaejasme and its major component, luteolin 7-O-glucoside, have a preventive effect on the development of atopic d...

journal_title：Planta medica

authors： Jo BG,Park NJ,Jegal J,Choi S,Lee SW,Yi LW,Kim SN,Yang MH

更新日期：2019-05-01 00:00:00

abstract：:A new minor diterpenoid alkaloid, caeruline, was isolated from DELPHINIUM CAERULEUM Jacq. ex Camb. Its structure was elucidated as 1 on the basis of spectral evidence. Along with this new compound, three known diterpenoid alkaloids were also isolated from this plant and identified as tatsiensine, delcosine, and lycoct...

journal_title：Planta medica

authors： Pan YJ,Wang R,Chen SN,Chen YZ

更新日期：1993-02-01 00:00:00

abstract：:PAPAVER SOMNIFERUM L. tissue cultures, issued from various explants (cotyledons, hypocotyls, roots) derived from plantlets belonging to two genotypes, were established on LS solid medium containing growth regulators (NAA, Kin) in various combinations. Hypocotyls and roots were found to be interesting explants to obtai...

journal_title：Planta medica

authors： Laurain-Mattar D,Gillet-Manceau F,Buchon L,Nabha S,Fliniaux MA,Jacquin-Bubreuil A

更新日期：1999-03-01 00:00:00

abstract：:A novel experimental model of free radical-induced emesis for screening anti-emetic compounds from natural sources was established. 2,2'-Azobis(2-amidinopropane) dihydrochloride (AAPH) dissolved in liposome induced emesis in young chickens, and the emesis was prevented by antioxidants including N-(2-mercaptopropionyl)...

journal_title：Planta medica

authors： Yang Y,Kinoshita K,Koyama K,Takahashi K,Tai T,Nunoura Y,Watanabe K

更新日期：1999-08-01 00:00:00

abstract：:The steam distilled oils both from flowers and leaves, as well as from total aerial parts of CHRYSANTHEMUM INDICUM L. (small-flowered form), were obtained and analyzed by GC and GC/MS. Their main components are borneol, chrysanthenone and bornyl acetate. ...

journal_title：Planta medica

authors： Stoianova-Ivanova B,Budzikiewicz H,Koumanova B,Tsoutsoulova A,Mladenova K,Brauner A

更新日期：1983-12-01 00:00:00

abstract：:The culture medium of Beauveria amorpha Hohn. exhibited strong radical scavenging properties. Activity-directed fractionation assisted by a radical scavenging assay on TLC afforded two active compounds which were identified as 6-methyl-2,4-dihydroxyphenyl 4-O-methyl-beta-D-glucopyranoside (1) and (-)-terredionol (2). ...

journal_title：Planta medica

authors： Hu F,Schmidt K,Stoyanova S,Zengzhi L,Gräfe U,Hamburger M

更新日期：2002-01-01 00:00:00

abstract：:Three new tetrahydroprotoberberine N-oxide alkaloids, (-)- cis-corydalmine N-oxide, (-)- trans-corydalmine N-oxide, and (-)- trans-isocorypalmine N-oxide, along with three known benzo[ C]phenanthridine alkaloids, norsanguinarine, dihydrosanguinarine, and oxysanguinarine, six known berberine alkaloids, (-)-tetrahydropa...

journal_title：Planta medica

authors： Chen JJ,Duh CY,Chen IS

更新日期：1999-10-01 00:00:00

abstract：:Effects of passage of subculture and several culture conditions, nutritional, hormonal and light conditions on 3,4-dihydroxyphenylalanine (DOPA) content were examined in callus of STIZOLOBIUM HASSJOO P IPER and T RACY. The favourable conditions for DOPA accumulation were found to be suboptimal conditions for growth, i...

journal_title：Planta medica

authors： Obata-Sasamoto H,Komamine A

更新日期：1983-10-01 00:00:00

abstract：:Valeriana officinalis L. is a popular herbal treatment for mild sleep disorders. Clinical and non-clinical studies found contradictory results for valerian extracts and single constituents regarding the influence on sleep parameters. It was the aim of this study to investigate the sedative effects of a valerian root e...

journal_title：Planta medica

authors： Chow NK,Fretz M,Hamburger M,Butterweck V

更新日期：2011-05-01 00:00:00

abstract：:This study demonstrated that plant extracts containing acetylenic isobutylamides and polyacetylenes, previously reported as occurring in Echinacea, have phototoxic antimicrobial activity against fungi, including clinically relevant pathogenic fungi. Results show that hexane extracts of Echinacea variably inhibit growt...

journal_title：Planta medica

authors： Binns SE,Purgina B,Bergeron C,Smith ML,Ball L,Baum BR,Arnason JT

更新日期：2000-04-01 00:00:00

abstract：:Natural compounds have been the first historical source of antithrombotic compounds (heparin, vitamin K antagonists, streptokinase, urokinase); molecules extracted from plants or animals still provide some of the most original and promising approaches for the discovery of new drugs in this class. In this review, we wi...

journal_title：Planta medica

authors： Beretz A,Cazenave JP

更新日期：1991-10-01 00:00:00

abstract：:Two new protopine-type alkaloids, argemexicaine A (1) and argemexicaine B (2), along with thirteen known alkaloids, were isolated from MeOH extracts of Formosan Argemone mexicana L. (Papaveraceae). Physical and spectral analyses, particularly IR and thermo-modulated 1D and 2D NMR, were used to determine the transannul...

journal_title：Planta medica

authors： Chang YC,Hsieh PW,Chang FR,Wu RR,Liaw CC,Lee KH,Wu YC

更新日期：2003-02-01 00:00:00

abstract：:Propolis has been reported to display a broad spectrum of biological activities such as anticancer, antioxidant, anti-inflammatory, antibiotic and antifungal properties, among others. There is great interest not only in the determination of the chemical composition of propolis but also in the understanding of the mech...

journal_title：Planta medica

authors： Tavares DC,Lira WM,Santini CB,Takahashi CS,Bastos JK

更新日期：2007-12-01 00:00:00

abstract：:Epilobium sp. are commonly used in traditional medicine in the treatment of early stages of benign prostatic hyperplasia and inflammation. It is suggested that a dominating constituent, oenothein B, is responsible for the extracts therapeutic effects. Several bioactivities were established for extracts and oenothein B...

journal_title：Planta medica

authors： Piwowarski JP,Bobrowska-Korczak B,Stanisławska I,Bielecki W,Wrzesien R,Granica S,Krupa K,Kiss AK

更新日期：2017-10-01 00:00:00

abstract：:The aerial parts of CUNILA SPICATA Benth., a Brasilian Lamiaceae, afforded a sesquiterpene-aldehyde named isocaryophyllen-13-al (beta-betulenal) ( 1). The constitution and configuration of this compound were established by high field NMR-techniques for the first time. ...

journal_title：Planta medica

authors： Manns D,Hartmann R

更新日期：1992-10-01 00:00:00

abstract：:The major alkaloids of PAPAVER TRINIIFOLIUM collected in two different parts of Anatolia have proved to be of the aporphine, morphinane and rhoeadine types. The two collections possessed different major alkaloids and the existence of chemical strains is indicated. In addition to the aporphine-(floripavidine), the morp...

journal_title：Planta medica

authors： Sariyar G

更新日期：1983-09-01 00:00:00

abstract：:Purification of a cytotoxic crude alkaloid extract of Cassytha filiformis led to the isolation of four known aporphine alkaloids: neolitsine, dicentrine, cassythine (= cassyfiline) and actinodaphnine. Their structures were determined by analysis of spectroscopic data. All isolated alkaloids were tested for their cytot...

journal_title：Planta medica

authors： Stévigny C,Block S,De Pauw-Gillet MC,de Hoffmann E,Llabrès G,Adjakidjé V,Quetin-Leclercq J

更新日期：2002-11-01 00:00:00

abstract：:The cytotoxicity of goniothalamin was found to be strong towards both cancerous (HGC-27, MCF-7, PANC-1, HeLa), and non-cancerous (3T3) cell lines, especially in cases of dividing cells. Drug exposure studies indicated that the cytotoxic action of goniothalamin was time- and dose-dependent. At the ultrastructural level...

journal_title：Planta medica

authors： Ali AM,Mackeen MM,Hamid M,Aun QB,Zauyah Y,Azimahtol HL,Kawazu K

更新日期：1997-02-01 00:00:00

abstract：:Human immunodeficiency virus (HIV) infection can result in oxidative stress through production of reactive oxygen species (ROS). Simultaneously, oxidative stress is able to activate the replication of virus and lead to the apoptosis of T lymphocytes which is the defense of the immune function. Ampelopsin, belonging to...

journal_title：Planta medica

authors： Ye J,Guan Y,Zeng S,Liu D

更新日期：2008-02-01 00:00:00

abstract：:Blood fluke of the genus Schistosoma are the etiological agents of human schistosomiasis, an important neglected tropical disease that afflicts over 200 million people worldwide. The treatment for this disease relies heavily on a single drug, praziquantel. Recent reports of praziquantel resistance raise concerns about...

journal_title：Planta medica

authors： Moraes Jd,Almeida AA,Brito MR,Marques TH,Lima TC,Sousa DP,Nakano E,Mendonça RZ,Freitas RM

更新日期：2013-03-01 00:00:00

abstract：:The natural compound tyropeptin A, a new peptidyl aldehyde proteasome inhibitor, was tested for its trypanocidal activity in vitro using culture-adapted bloodstream forms of Trypanosoma brucei. The concentrations of tyropeptin A required to reduce the growth rate by 50 % and to kill all cells were 10 and 100 times low...

journal_title：Planta medica

authors： Steverding D,Pemberton AJ,Royle H,Spackman RW,Rivett AJ

更新日期：2006-06-01 00:00:00

abstract：:Juniperus excelsa fruit essential oil as well as J. oxycedrus, Cedrus libani, and Pinus pinea wood essential oils have been obtained with yields between 2.2 ± 0.3 % to 3.4 ± 0.5 % and analyzed by gas chromatography. Sesquiterpenes mainly characterized C. libani and J. oxycedrus essential oils, while in P. pinea and J....

journal_title：Planta medica

authors： Saab AM,Guerrini A,Sacchetti G,Maietti S,Zeino M,Arend J,Gambari R,Bernardi F,Efferth T

更新日期：2012-12-01 00:00:00

abstract：:Infusions of Citrullus colocynthis Schrad. (Cucurbitaceae) fruits are traditionally used as antidiabetic medication in Mediterranean countries, but to our knowledge no studies have been undertaken so far to determine the possible mechanisms involved in the antidiabetic properties of the fruit. The present study was de...

journal_title：Planta medica

authors： Nmila R,Gross R,Rchid H,Roye M,Manteghetti M,Petit P,Tijane M,Ribes G,Sauvaire Y

更新日期：2000-06-01 00:00:00

abstract：:Myrrh is the oleo-gum resin of mainly Commiphora molmol and as a powdered substance, one compound in the traditional medicinal product Myrrhinil-Intest®, which has been used for the treatment of unspecific, inflammatory intestinal disorders. The aim of the present study was to evaluate the antispasmodic effect of myrr...

journal_title：Planta medica

authors： Vissiennon C,Goos KH,Goos O,Nieber K

更新日期：2015-01-01 00:00:00

abstract：:Menopause is characterized by deep metabolic disturbances, including decreased insulin sensitivity, adiposity, and changes in lipid profiles. Estrogen replacement therapy can partially reverse these changes, and while it is safe in most healthy postmenopausal women, there are still existing concerns regarding an incre...

journal_title：Planta medica

authors： Jeremic I,Petricevic S,Tadic V,Petrovic D,Tosic J,Stanojevic Z,Petronijevic M,Vidicevic S,Trajkovic V,Isakovic A

更新日期：2019-04-01 00:00:00

abstract：:In this study we investigated the effects of concomitant food intake on the bioavailability of distinct boswellic acids (BAs) from the test preparation BSE-018, a dry extract from Boswellia serrata gum resin. In a randomised, open, single-dose, two-way crossover study, healthy male subjects received three capsules of ...

journal_title：Planta medica

authors： Sterk V,Büchele B,Simmet T

更新日期：2004-12-01 00:00:00