Abstract:
:Bioassay-guided fractionation of the H(2)O extract of the seeds of Psoralea corylifolia furnished one hepatoprotective compound, bakuchiol (1), together with two moderately active compounds, bakuchicin (2) and psoralen (3), on tacrine-induced cytotoxicity in human liver-derived Hep G2 cells. The EC(50) values of compounds 1 - 3 are 1.0, 47.0, 50.0 microg/ml, respectively. Silymarin as a positive control showed the EC(50) value with 5.0 microg/ml.
journal_name
Planta Medjournal_title
Planta medicaauthors
Cho H,Jun JY,Song EK,Kang KH,Baek HY,Ko YS,Kim YCdoi
10.1055/s-2001-18347subject
Has Abstractpub_date
2001-11-01 00:00:00pages
750-1issue
8eissn
0032-0943issn
1439-0221journal_volume
67pub_type
杂志文章相关文献
PLANTA MEDICA文献大全abstract::Characterization of an alkali-soluble isolate from Pinus nigra Arnold (Pinaceae) seed cones by thioacidolysis revealed a significant phenylpropanoid (i.c. lignin) component which may provide the observed anti-HIV-1 activity for this substance. ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957801
更新日期:1996-02-01 00:00:00
abstract::Three new vermistatin derivatives, 6-demethylpenisimplicissin (1), 5'-hydroxypenisimplicissin (2), and 2''-epihydroxydihydrovermistatin (3), along with five known vermistatin analogues, methoxyvermistatin (4), vermistatin (5), 6-demethylvermistatin (6), hydroxyvermistatin (7), and penisimplicissin (8), were isolated f...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0034-1382859
更新日期:2014-07-01 00:00:00
abstract::The tertiary and quaternary alkaloids isolated from the stem bark, root bark and seeds of Peschiera fuchsiaefolia are reported. The tertiary alkaloid crude extract from the stem bark was tested in vitro against Plasmodium falciparum on the basis of the antimalarial use of the plant. It showed good activity against bot...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-0029-1243122
更新日期:2000-02-01 00:00:00
abstract::The formation of lactonic amines 3 and 4 from alpha-methylene-gamma-butyrolactone (tulipalin A) 1 is described. ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-969585
更新日期:1985-12-01 00:00:00
abstract::Various locations in Switzerland were screened for Petasites hybridus plants with high petasin and low pyrrolizidine alkaloid content. The mean petasin content of the various populations ranged from 7.4 to 15.3 mg/g dry weight in rhizomes and from 3.3 to 11.4 mg/g dry weight in leaves. Mean pyrrolizidine alkaloid cont...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957422
更新日期:1998-04-01 00:00:00
abstract::A cytotoxic compound was purified from the root of Angelica gigas Nakai by normal phase HPLC. As a result of the structure analysis by mass, IR, 1H-NMR, and 13C-NMR spectrometry, the compound was identified as decursinol angelate, a structural isomer of decursin, and characterized originally from Sesei grandivittatum....
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2006-957701
更新日期:1997-08-01 00:00:00
abstract::Novel therapies are needed to address the public health problem posed by methicillin-resistant STAPHYLOCOCCUS AUREUS (MRSA). In this study, we determined the effects of combinations of antibiotics and plant polyphenols against 20 clinical isolates of MRSA. The IN VITRO activities of 10 antibiotics and 15 natural polyp...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2008-1074559
更新日期:2008-06-01 00:00:00
abstract::The benzophenanthridine alkaloids sanguinarine and chelerythrine of Chelidonium majus, L. (Papaveraceae), are potent inhibitors of 5-lipoxygenase in polymorphonuclear leukocytes and 12-lipoxygenase in mouse epidermis, while the activity of soybean lipoxygenase is not influenced. The extract of the herb of Ch.majus als...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957924
更新日期:1996-10-01 00:00:00
abstract::Because Rhodiola plants are known to have a protective effect on diabetic nephropathy, this study aimed to investigate the inhibitory effect of salidroside, the main active component of Rhodiola plants, on high glucose-induced mesangial cell proliferation and its possible mechanism. Salidroside (1 approximately 100 mi...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0029-1185717
更新日期:2009-09-01 00:00:00
abstract::Many compounds of plant origin have been identified that inhibit different stages in the replication cycle of human immunodeficiency virus (HIV): 1) virus adsorption: chromone alkaloids (schumannificine), isoquinoline alkaloids (michellamines), sulphated polysaccharides and polyphenolics, flavonoids, coumarins (glycoc...
journal_title:Planta medica
pub_type: 杂志文章,评审
doi:10.1055/s-2006-957384
更新日期:1998-03-01 00:00:00
abstract::Tryptanthrin and (E,Z)-3-(4-hydroxy-3,5-dimethoxybenzylidene)indolinone (indolinone) were recently isolated from Isatis tinctoria as potent anti-inflammatory and antiallergic alkaloids, and shown to inhibit COX-2, 5-LOX catalyzed leukotriene synthesis, and mast cell degranulation at low µM to nM concentrations. To ass...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0042-110323
更新日期:2016-08-01 00:00:00
abstract::Products derived from Noni fruit (Morinda citrifolia) have been commercialised in the USA since the 1990s and are increasingly distributed all over the world. A large number of beneficial effects have been claimed for Noni. Fruit juice of Noni has been approved as a Novel Food by the European Commission in 2003. This ...
journal_title:Planta medica
pub_type: 杂志文章,评审
doi:10.1055/s-2007-967115
更新日期:2007-03-01 00:00:00
abstract::Variability in the oil content in natural populations of Cymbopogon jawarancusa is discussed. Races rich in piperitone, phellandrene and other chemical constituents have been identified. The oil producing ability was largely genetic and showed heritability of 79.0 percent. ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-971731
更新日期:1981-04-01 00:00:00
abstract::A new furoclerodane, croblongifolin, together with one known clerodane, crovatin and one known labdane, nidorellol, were isolated from the stem bark of Croton oblongifolius. Structures were established based on spectroscopic and X-ray analysis. Croblongifolin showed a significant cytotoxicity against various human tum...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2002-23138
更新日期:2002-03-01 00:00:00
abstract::When added to suspension cultures of CATHARANTHUS ROSEUS, abscisic acid (ABA) stimulated intracellular accumulation of the indole alkaloids catharanthine and ajmalicine in both flask and 30 litre fermenter-scale systems. The response varied, and depended upon the cell line, the concentration and source of the ABA, and...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-962775
更新日期:1987-10-01 00:00:00
abstract::Reinvestigating the constituents of the roots of Vitis thunbergii Sieb. & Zucc. led to the isolation of three new resveratrol derivatives, vitisinols E-G (1-3), together with 14 known compounds. The structures of compounds 1-3 were established by application of spectroscopic analyses (NMR, MS, UV, and IR). ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0029-1185404
更新日期:2009-06-01 00:00:00
abstract::Nano-encapsulation of several natural products has become an important tool in enhancing the bioavailability of some modern drugs against many diseases. Pelargonidin is an anthocyanidin found in many fruits and vegetables. Pelargonidin is loaded with poly-lactide-co-glycolic-acid, a non-toxic biodegradable polymer, to...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0043-100017
更新日期:2017-03-01 00:00:00
abstract::IN VITRO plant regeneration of Gentiana macrophylla Pall. and determination of gentiopicroside content during somatic embryogenesis are described in the present work. The highest percentage of embryogenic callus formation was observed in Murashige and Skoog (MS) medium supplemented with 1.0 mg/L 2,4-dichlorophenoxyace...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0029-1185808
更新日期:2009-12-01 00:00:00
abstract::The seed pods of Erythrina latissima yielded erysotrine, erysodine, syringaresinol, vanillic acid, a new erythrina alkaloid, (+)-10,11-dioxoerysotrine, which was lethal to brine shrimp and 2-(5'-hydroxy-3'-methoxy phenyl)-6-hydroxy-5-methoxybenzofuran, which showed strong antimicrobial activity against the yeast spore...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2002-32891
更新日期:2002-07-01 00:00:00
abstract::Astilbin, a flavonoid compound, was isolated from the rhizome of Smilax glabra Roxb. This study was conducted to investigate the efficacy of astilbin on experimental diabetic nephropathy (DN) in vivo and in vitro and its possible mechanisms. Astilbin was added in high glucose stimulated HK-2 cells, streptozotocin-indu...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0029-1185802
更新日期:2009-11-01 00:00:00
abstract::Ligusticum canbyi (J.M. Coult & Rose) is a medicinal understory forest species used in traditional rituals and ceremonies for spiritual enlightenment and improved mental health. Very little is known about the phytochemical complexity or diversity of L. canbyi tissues or extracts. The current study was undertaken to de...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0033-1350618
更新日期:2013-09-01 00:00:00
abstract::In this study the skin permeation and the topical anti-inflammatory properties of ginger extracts were investigated. A commercial ginger dry extract (DE) and a gingerols-enriched dry extract (EDE) were evaluated for their in vivo topical anti-inflammatory activity by inhibition of Croton oil-induced ear oedema in mice...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-993741
更新日期:2007-12-01 00:00:00
abstract::Capsaicin and 6-gingerol, pungent components of chilli pepper and ginger, are known as dietary agonists of transient receptor potential vanilloid-1. Transient receptor potential vanilloid-1 nerve fibers are recognized to play a role in gastric mucosal integrity in rats. In the present studies, we examined the acute ef...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0032-1315387
更新日期:2012-11-01 00:00:00
abstract::Four new (1-4) and two known compounds (5, 6) were isolated from the aerial parts of Araucaria cunninghamii. By analysis of UV, IR, MS, and NMR, the new compounds were identified as ENT-19-(Z)-coumaroyloxylabda-8(17),13(16),14-triene (1), ENT-19-( E)-coumaroyloxylabda-8(17),13(16),14-triene (2), shikimic acid N-butyl ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0030-1250570
更新日期:2011-03-01 00:00:00
abstract::Leaves and stem barks of S. scheffleri Gilg afforded eight dihydroindole alkaloids. Four tertiary monomers (O-methyl Na-acetylstrychnosplendine, Na-acetylstrychnosplendine, strychnobrasiline and strychnofendlerine) have been isolated from leaf material while stem barks yielded one tertiary monomer (desacetylisoretulin...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-971656
更新日期:1981-08-01 00:00:00
abstract::Fractionation of the aqueous extract of Derris scandens stems extract using tests for eicosanoid inhibition resulted in the isolation of three isoflavonoids, genistein, its 7- O-alpha-rhamno(1-->6)-beta-glucosyl glycoside, a new compound, and two known isoprenyl derivatives 3'-gamma,gamma-dimethylallylweighteone and s...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2004-827147
更新日期:2004-06-01 00:00:00
abstract::Three new β-indoloquinazoline alkaloids, orirenierine A (1), B (2) and C (4), together with eleven known compounds were isolated from the methanol extract of the stems of Oricia renieri. The structures of all compounds were determined by comprehensive analyses of their spectroscopic data and comparison with literature...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0031-1280227
更新日期:2012-01-01 00:00:00
abstract::From the leaves of DIGITALIS LANATA Ehrh. two new Cardenolides have been found and structurally elucidated as Digoxigenin-3-O-beta- D-digitoxosido-beta- D-digitoxosido-beta- D-xyloside bei TLC and spectroscopic methods. ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-969697
更新日期:1984-06-01 00:00:00
abstract::Three pyrrolizidine alkaloids were isolated from Eupatorium portoricense and their structures elucidated by spectroscopic methods as (-)-viridifloryl-supinidine (amabiline), (-)-viridifloryl-heliotridine (echinatine), and C12- O-acetyl-(-)-viridifloryl-heliotridine (O(12)-acetylechinatine). ...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2006-958112
更新日期:1995-08-01 00:00:00
abstract::The quantification of free and total alkannins in 13 endemic Anatolian Alkanna species is described for the first time. Extraction of the samples was performed by sonication with hexane, followed by hydrolysis in 1 N NaOH. For analysis, a new HPLC method, utilizing reversed phase material (Synergi Max RP), was develop...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-967110
更新日期:2007-03-01 00:00:00