Quantitative analysis of petasin and pyrrolizidine alkaloids in leaves and rhizomes of in situ grown Petasites hybridus plants.

abstract：:Lime flowers, traditionally used for medical purposes for the treatment of symptoms of the common cold and mental stress, consist of the dried inflorescences including the floral bracts of Tilia cordata, Tilia platyphyllos, Tilia × vulgaris, or mixtures thereof. During phytochemical investigations, 6 different alkaloi...

journal_title：Planta medica

authors： Symma N,Bütergerds M,Sendker J,Petereit F,Hake A,Düfer M,Hensel A

更新日期：2021-01-12 00:00:00

abstract：:The inhibitory action of the major constituent of Sebastiania schottiana (Euphorbiaceae), 2-hydroxy-4,6-dimethoxyacetophenone (xanthoxyline) on contractions induced by agonists and electrical stimulation of smooth and cardiac muscle preparations was analysed. Xanthoxyline (30 to 300 microM) inhibited contractions of t...

journal_title：Planta medica

authors： Calixto JB,Miguel OG,Yunes RA,Rae GA

更新日期：1990-02-01 00:00:00

abstract：:An ionpair-HPLC-technic using a reversed-phase column was developed to screen plant extracts for cardiotonic amines and to isolate them in a preparative scale for direct MS and pharmacological investigations. By this method the positive inotropic tyramine could be isolated from Selenicereus grandiflorus (L.) Britt et ...

journal_title：Planta medica

authors： Wagner H,Grevel J

更新日期：1982-01-01 00:00:00

abstract：:The antimycobacterial quinolones 1-methyl-2-undecyl-4-quinolone, dihydroevocarpine and evocarpine as well as the indoloquinazoline alkaloids rutaecarpine and evodiamine - all from the Chinese medicinal herb Evodia rutaecarpa - were tested in two in vitro assays, for cytotoxicity and interaction with p-glycoprotein (p-...

journal_title：Planta medica

authors： Adams M,Mahringer A,Kunert O,Fricker G,Efferth T,Bauer R

更新日期：2007-12-01 00:00:00

abstract：:This study demonstrated that plant extracts containing acetylenic isobutylamides and polyacetylenes, previously reported as occurring in Echinacea, have phototoxic antimicrobial activity against fungi, including clinically relevant pathogenic fungi. Results show that hexane extracts of Echinacea variably inhibit growt...

journal_title：Planta medica

authors： Binns SE,Purgina B,Bergeron C,Smith ML,Ball L,Baum BR,Arnason JT

更新日期：2000-04-01 00:00:00

abstract：:We describe in this paper that the alkaloid 4-methylaaptamine, isolated from the marine sponge Aaptos aaptos, inhibited HSV-1 infection. We initially observed that 4-methylaaptamine inhibited HSV-1 replication in Vero cells in a dose-dependent manner with an EC50 value of 2.4 microM. Moreover, the concentration requir...

journal_title：Planta medica

authors： Souza TM,Abrantes JL,de A Epifanio R,Leite Fontes CF,Frugulhetti IC

更新日期：2007-03-01 00:00:00

abstract：:In the extremely skin irritant and caustic latex of Excoecaria agallocha the major part of the polyfunctional diterpene esters (DTE) (group I) are aliphatic polyunsaturated 9,13,14-orthoesters of the daphnane-type parent alcohol 5 beta-hydroxyresiniferonol-6 alpha, 7 alpha-epoxide, esterified simultaneously in their 2...

journal_title：Planta medica

authors： Karalai C,Wiriyachitra P,Opferkuch HJ,Hecker E

更新日期：1994-08-01 00:00:00

abstract：:The flower buds of Lonicera japonica are widely used in Chinese medicine for their anti-inflammatory properties. The reason why L. japonica has potent and significant effects is that it contains various active components, especially chlorogenic acid (CGA). In the present study, we isolated a hydroxycinnamoyl-CoA quina...

journal_title：Planta medica

authors： Peng X,Li W,Wang W,Bai G

更新日期：2010-11-01 00:00:00

abstract：:Five known abietane diterpenes, fatty acid esters of 7alpha-acyloxy-6beta-hydroxyroyleanone (1), grandidone A (2), 7alpha-acetoxy-6beta-hydroxyroyleanone (3), 6beta,7alpha-dihydroxyroyleanone (4), and coleon U (5), isolated from Plectranthus grandidentatus Gürke, were evaluated for their in vitro antiproliferative act...

journal_title：Planta medica

authors： Marques CG,Pedro M,Simões MF,Nascimento MS,Pinto MM,Rodríguez B

更新日期：2002-09-01 00:00:00

abstract：:A new tetrahydrofuran lignan, named henricine ( 1), was isolated from the stems of SCHISANDRA HENRYI. High resolution COSY spectrum was used in the structural elucidation. ...

journal_title：Planta medica

authors： Lian-Niang L,Hong X

更新日期：1986-12-01 00:00:00

abstract：:A study of secondary metabolites from the bark of Alnus glutinosa led to the isolation of fourteen diarylheptanoids: oregonin (1), platyphylloside (2), rubranoside A (3), rubranoside B (4), hirsutanonol (5), hirsutenone (6), hirsutanonol-5-O-β-D-glucopyranoside (7), platyphyllonol-5-O-β-D-xylopyranoside (8), aceroside...

journal_title：Planta medica

authors： Novaković M,Stanković M,Vučković I,Todorović N,Trifunović S,Tešević V,Vajs V,Milosavljević S

更新日期：2013-04-01 00:00:00

abstract：:In Brazil, Plectranthus species are known as "boldo" and have been used in popular medicine for analgesic and dyspeptic purposes. Plectranthus need to be well identified in order to be used as commercially genuine medicinal plants. Here we describe AFLP DNA patterns able to distinguish among different Pectranthus spec...

journal_title：Planta medica

authors： Passinho-Soares H,Felix D,Kaplan MA,Margis-Pinheiro M,Margis R

更新日期：2006-08-01 00:00:00

abstract：:Synthetic butylidenephthalide (Bdph), 60 mg/kg per os (p.o.) given 3 h prior to injection of pituitrin (4 U/kg, i.v.), significantly prevented T-wave lowering on lead II electrocardiograph in unanesthetized rats. The effective dose, 60 mg/kg, was about 1/56th of the median lethal dose (LD50, p.o.) in rats. However, Bd...

journal_title：Planta medica

authors： Ko WC,Sheu JR,Tzeng SH,Chen CM

更新日期：1998-04-01 00:00:00

abstract：:In this study we investigate the active constituents of the rhizome of Zingiber officinale, Roscoe (ginger) and determine their activity on glucose uptake in cultured L6 myotubes and the molecular mechanism underlying this action. Freeze-dried ginger powder was extracted with ethyl acetate (1 kg/3 L) to give the total...

journal_title：Planta medica

authors： Li Y,Tran VH,Duke CC,Roufogalis BD

更新日期：2012-09-01 00:00:00

abstract：:YANG XIN is a traditional Chinese medicine formulation used for nervous fatigue and consists of a proprietary blend of concentrated extracts from 18 plant ingredients. The 18 constituent plant ingredients, YANG XIN capsules, and formulations 2014-005_1 A and 1B were extracted by consecutive 24-hour macerations with di...

journal_title：Planta medica

authors： Almalki AJ,Zaher A,Simithy J,Keller WJ,Tripp M,Calderón AI

更新日期：2016-08-01 00:00:00

abstract：:A lyophilised hydroalcoholic extract of Melissa officinalis L. (Lamiaceae) has been evaluated for behavioral effects in mice. According to the traditional use of M. officinalis, sedative properties have been confirmed for low doses by the decrease of behavioral parameters measured in a non-familiar environment test (s...

journal_title：Planta medica

authors： Soulimani R,Fleurentin J,Mortier F,Misslin R,Derrieu G,Pelt JM

更新日期：1991-04-01 00:00:00

abstract：:Ten new nervogenic acid derivatives (1-4, 6-11) and one known compound (5) have been isolated from Liparis nervosa. Their structures were determined using extensive spectroscopic analysis, including 1D and 2D NMR experiments. Compounds 3, 4, 9, 10, and 11 were evaluated for their cytotoxicity against A549, H460, Hela,...

journal_title：Planta medica

authors： Huang S,Zhou XL,Wang CJ,Wang HY,Wang YS,Shan LH,Weng J

更新日期：2013-03-01 00:00:00

abstract：:A new eudesmanolide sesquiterpene, sivasinolide 6-O-angelate (1), was isolated from the aerial parts of Anthemis ruthenica together with the known compounds chrysanin (2), tanacin (3), 3 beta-hydroxycostunolide (4), centauridin (5), and centaureidin (6). The compounds were obtained by means of bioactivity-guided fract...

journal_title：Planta medica

authors： Hajdú Z,Zupkó I,Réthy B,Forgo P,Hohmann J

更新日期：2010-01-01 00:00:00

abstract：:Geniposide, a main iridoid glucoside component of gardenia fruit, has been shown to possess anti-inflammatory activity. However, its potential use for acute lung injury (ALI) has not yet been studied. The aim of this study was to evaluate the anti-inflammatory properties of geniposide using a mouse ALI model. ALI was ...

journal_title：Planta medica

authors： Xiaofeng Y,Qinren C,Jingping H,Xiao C,Miaomiao W,Xiangru F,Xianxing X,Meixia H,Jing L,Jingyuan W,Xinxin C,Hongyu L,Yanhong D,Lanxiang J,Xuming D

更新日期：2012-04-01 00:00:00

abstract：:Activity-guided fractionation of the dichloromethane extract from leaves of Piper fulvescens, using an agar overlay bioautographic method, led to the isolation of three antifungal neolignans identified as conocarpan, eupomatenoid 5 and eupomatenoid 6. The minimal inhibitory concentration of these three neolignans agai...

journal_title：Planta medica

authors： Freixa B,Vila R,Ferro EA,Adzet T,Cañigueral S

更新日期：2001-12-01 00:00:00

abstract：:In garlic (Allium sativum L.) the enzyme alliin lyase catalyzes the cleavage of alliin into allicin which reacts further to furnish ajoene. A simultaneous determination of allicin and ajoene is introduced which, in contrast to the determination of alliin only, allows for the testing of the activity of alliin lyase. It...

journal_title：Planta medica

authors： Blania G,Spangenberg B

更新日期：1991-08-01 00:00:00

abstract：:DNA technology provides a powerful tool to complement chemical analyses for authentication of Chinese medicinal plants and to ensure that herbal materials are not contaminated with ineffective or potentially harmful substitutes or adulterants. In the last two decades molecular biotechnology has provided sophisticated ...

journal_title：Planta medica

authors： Heubl G

更新日期：2010-12-01 00:00:00

abstract：:Two triterpenoidal saponins having phytolaccagenin as the aglycone were isolated from the roots of Phytolacca esculenta (Phytolaccaceae). The structures of two new saponins, esculentoside I and esculentoside N, were established to be 3-O-[beta-D-glucopyranosyl-(1----4)-beta-D- glucopyranosyl]-28-O-beta-D-glucopyranosy...

journal_title：Planta medica

authors： Yi YH

更新日期：1992-02-01 00:00:00

abstract：:Citral, 3,7-dimethyl-2,6-octadien-1-al, a key component of the lemon-scented essential oils extracted from several herbal plants such as lemon grass (Cymbopogon citratus), melissa (Melissa officinalis), verbena (Verbena officinalis) is used as a food additive and as a fragrance in cosmetics. In this study, we investig...

journal_title：Planta medica

authors： Dudai N,Weinstein Y,Krup M,Rabinski T,Ofir R

更新日期：2005-05-01 00:00:00

abstract：:Leaves and stem barks of S. scheffleri Gilg afforded eight dihydroindole alkaloids. Four tertiary monomers (O-methyl Na-acetylstrychnosplendine, Na-acetylstrychnosplendine, strychnobrasiline and strychnofendlerine) have been isolated from leaf material while stem barks yielded one tertiary monomer (desacetylisoretulin...

journal_title：Planta medica

authors： Caprasse M,Angenot L

更新日期：1981-08-01 00:00:00

abstract：:Amphotericin B (AmB) is a representative antibiotic for the control of serious fungal infections, and its fungicidal activity was greatly enhanced by allicin, an allyl-sulfur compound from garlic. In addition to the plasma membrane permeability change, AmB induced vacuole membrane damage so that the organelles were vi...

journal_title：Planta medica

authors： Ogita A,Fujita K,Taniguchi M,Tanaka T

更新日期：2006-10-01 00:00:00

abstract：:The steam distilled oils both from flowers and leaves, as well as from total aerial parts of CHRYSANTHEMUM INDICUM L. (small-flowered form), were obtained and analyzed by GC and GC/MS. Their main components are borneol, chrysanthenone and bornyl acetate. ...

journal_title：Planta medica

authors： Stoianova-Ivanova B,Budzikiewicz H,Koumanova B,Tsoutsoulova A,Mladenova K,Brauner A

更新日期：1983-12-01 00:00:00

abstract：:Variability in the oil content in natural populations of Cymbopogon jawarancusa is discussed. Races rich in piperitone, phellandrene and other chemical constituents have been identified. The oil producing ability was largely genetic and showed heritability of 79.0 percent. ...

journal_title：Planta medica

authors： Dhar AK,Thappa RK,Atal CK

更新日期：1981-04-01 00:00:00

abstract：:3,6'-Disinapoylsucrose is a major active component of the herb Polygala tenuifolia which has long been used for relieving tranquilization, uneasiness of the mind, and improving learning and memory. Our previous study found that 3,6'-disinapoylsucrose had a very low oral bioavailability. Its mechanisms of absorption in...

journal_title：Planta medica

authors： Chen Y,Liu X,Pan R,Zhu X,Steinmetz A,Liao Y,Wang N,Peng B,Chang Q

更新日期：2013-10-01 00:00:00

abstract：:Embelia ribes Burm. f. (Myrsinaceae) is one of the important plants used in Indian traditional medicine. RAPD-PCR analysis was performed to obtain species-specific DNA fragments. A band of 906 bp that was specific to Embelia ribes irrespective of the geographical source was obtained using the random decamer primer OPF...

journal_title：Planta medica

authors： Devaiah KM,Venkatasubramanian P

更新日期：2008-02-01 00:00:00