Light-mediated antifungal activity of Echinacea extracts.

abstract：:In order to evaluate the potency of novel antiviral drugs, 11 natural sulfated polysaccharides (SPs) from 10 green algae ( Enteromorpha compressa, Monostroma nitidum, Caulerpa brachypus, C. okamurai, C. scapelliformis, Chaetomorpha crassa, C. spiralis, Codium adhaerens, C. fragille, and C. latum) and 4 synthetic sulfa...

journal_title：Planta medica

authors： Lee JB,Hayashi K,Maeda M,Hayashi T

更新日期：2004-09-01 00:00:00

abstract：:The therapeutic goal in liver fibrosis is the reversal of fibrosis and the selective clearance of activated hepatic stellate cells (HSCs) by inducing apoptosis. Over the past several years, we have screened for natural products that mediate apoptosis in activated HSCs. Among the candidate compounds, honokiol, isolated...

journal_title：Planta medica

authors： Park EJ,Zhao YZ,Kim YH,Lee BH,Sohn DH

更新日期：2005-01-01 00:00:00

abstract：:Airway remodeling is an important characteristic of asthma, linking inflammation with airway hyperresponsiveness. Baicalin, a major active component, was isolated from Radix Scutellariae. Many studies show that baicalin has anti-inflammatory, anti-bacterial, and anti-allergic effects. Here we investigate the influence...

journal_title：Planta medica

authors： Sun J,Li L,Wu J,Liu B,Gong W,Lv Y,Luo Q,Duan X,Dong J

更新日期：2013-03-01 00:00:00

abstract：:Human vascular endothelial cells (HUVECs) were exposed to CoCl2 as an in vitro model of hypoxia. Expression of VCAM-1 (vascular cell adhesion molecule), reduction of PECAM-1 (platelet endothelial cell adhesion molecule) and cytoskeletal changes without alterations in cell viability were observed. HUVECs were also expo...

journal_title：Planta medica

authors： Montopoli M,Froldi G,Comelli MC,Prosdocimi M,Caparrotta L

更新日期：2007-03-01 00:00:00

abstract：:Nano-encapsulation of several natural products has become an important tool in enhancing the bioavailability of some modern drugs against many diseases. Pelargonidin is an anthocyanidin found in many fruits and vegetables. Pelargonidin is loaded with poly-lactide-co-glycolic-acid, a non-toxic biodegradable polymer, to...

journal_title：Planta medica

authors： Samadder A,Tarafdar D,Abraham SK,Ghosh K,Khuda-Bukhsh AR

更新日期：2017-03-01 00:00:00

abstract：:Six new triterpenoid saponins, psychotrianosides A-F (1-6), and two known triterpenoid saponins, psychotrianoside G (7) and ardisianoside D (8), were isolated from Psychotria sp. Their structures were determined mainly by spectroscopic methods. The cytotoxic activities of 1-8 against five human cancer cell lines (MDA-...

journal_title：Planta medica

authors： Zhang CX,Zhang DM,Chen MF,Guan SY,Yao JH,He XX,Lei LF,Zhong Y,Wang ZF,Ye WC

更新日期：2013-07-01 00:00:00

abstract：:In the course of our screening program for acyl-CoA : cholesterol acyltransferase (ACAT) inhibitors from Korean herbal medicines, ACAT inhibitors were isolated from the hairy roots of Panax ginseng (Araliaceae) and identified as panaxynol, panaxydol, panaxydiol, and panaxytriol. These active compounds inhibit rat live...

journal_title：Planta medica

authors： Kwon BM,Ro SH,Kim MK,Nam JY,Jung HJ,Lee IR,Kim YK,Bok SH

更新日期：1997-12-01 00:00:00

abstract：:Esters of 13-hydroxylupanine and 4-hydroxylupanine with acetic, propionic, butyric, isobutyric, valeric, isovaleric, tiglic, benzoic, and TRANS-cinnamic acid have been synthesized and characterized by capillary gas-liquid chromatography and mass spectrometry (EI-MS, CI-MS). In LUPINUS POLYPHYLLUS, L. ALBUS, L. ANGUSTI...

journal_title：Planta medica

authors： Mühlbauer P,Witte L,Wink M

更新日期：1988-06-01 00:00:00

abstract：:Overexpression of the protein transporter P-glycoprotein (Pgp, MDR1) at the cell surface is a major cause of multidrug resistance (MDR) and poor response to treatment in cancer chemotherapy and therapy for leishmaniasis. The present study shows that conferone, a sesquiterpene coumarin ether isolated for the first time...

journal_title：Planta medica

authors： Barthomeuf C,Demeule M,Grassi J,Saidkhodjaev A,Beliveau R

更新日期：2006-06-01 00:00:00

abstract：:Increased osteoclastic bone resorption plays a central role in the pathogenesis of many bone diseases. Ganoderma lucidum is known for medicinal effects such as anti-inflammatory and anti-bone resorption activities. In this study, we investigated the inhibitory effects of ganoderic acids isolated from G. lucidum on ost...

journal_title：Planta medica

authors： Liu J,Shiono J,Shimizu K,Kondo R

更新日期：2010-02-01 00:00:00

abstract：:Activator protein 1 (AP-1) is a transcription factor which plays a critical role in inflammation and carcinogenesis. The present study was conducted to investigate the effect of berberine, an isoquinoline alkaloid present in plants of the genera Berberis and Coptis, on the activity of AP-1 using a reporter gene assay ...

journal_title：Planta medica

authors： Fukuda K,Hibiya Y,Mutoh M,Koshiji M,Akao S,Fujiwara H

更新日期：1999-05-01 00:00:00

abstract：:Comparative study of the seeds of two Cucurbitaceae Momordica charantia L. and Herpetospermum caudigerum Wall. shows and important difference for their metabolism concerning particularly aspartic acid. Momordica can produce vicin, while for Herpetospermum, this amino acid would give asparagin. In the other hand, betwe...

journal_title：Planta medica

authors： Barron D,Kaouadji M,Mariotte AM

更新日期：1982-11-01 00:00:00

abstract：:Some diterpenoids show various biological activities, including anti-inflammatory, anti-HIV and anti-tumor activity. Previously, we have focused our research on the apoptosis-inducing properties of diterpenoids and found that some ent-kaurene-type diterpenoids induced apoptosis in human leukemia HL-60 cells. In this s...

journal_title：Planta medica

authors： Kondoh M,Nagashima F,Suzuki I,Harada M,Fujii M,Asakawa Y,Watanabe Y

更新日期：2005-11-01 00:00:00

abstract：:A methanolic extract of Commelina communis showed potent inhibitory activity against alpha-glucosidase. One pyrrolidine alkaloid, 2,5-dihydroxymethyl-3,4-dihydroxypyrrolidine (DMDP, 1) and four piperidine alkaloids, 1-deoxymannojirimycin (2), 1-deoxynojirimycin (3), alpha-homonojirimycin (4) and 7-O-beta-D-glucopyrano...

journal_title：Planta medica

authors： Kim HS,Kim YH,Hong YS,Paek NS,Lee HS,Kim TH,Kim KW,Lee JJ

更新日期：1999-06-01 00:00:00

abstract：:Sangre de Grado extract used by Peruvian natives as a cicatrizant agent, was collected from trees of the species Croton lechleri growing in the Peruvian jungle. The Sangre de Grado was found to contain one alkaloid identified as taspine and which was shown to be the active cicatrizant principle by an in vivo test in m...

journal_title：Planta medica

authors： Vaisberg AJ,Milla M,Planas MC,Cordova JL,de Agusti ER,Ferreyra R,Mustiga MC,Carlin L,Hammond GB

更新日期：1989-04-01 00:00:00

abstract：:The solid dispersion of a poorly water-soluble Silybum marianum extract (SME) was prepared by a one-step fluid-bed coating technique depositing onto non-pareil pellets. In vitro evaluation indicated that this technique was highly efficient and reproducible producing pellets with acceptable appearance, flowability, fri...

journal_title：Planta medica

authors： Sun N,Zhang X,Lu Y,Wu W

更新日期：2008-02-01 00:00:00

abstract：:The active ingredient dl-tetrahydropalmatine (THP) isolated from the traditional Chinese herb Corydalis racemosa has been found to have antihypertensive effects. However, severe cardiac and neurological toxic effects were reported from using this herb for the treatment of pain. In an isolated perfused rat heart model,...

journal_title：Planta medica

authors： Chan P,Chiu WT,Chen YJ,Wu PJ,Cheng JT

更新日期：1999-05-01 00:00:00

abstract：:The species Ageratina pichinchensis (Asteraceae) has been used for a long time in Mexican traditional medicine for the treatment of different skin conditions and injuries. In this study, the healing capacity of the plant extracts obtained was evaluated and, in order to understand the mechanism of healing, we also anal...

journal_title：Planta medica

authors： Romero-Cerecero O,Zamilpa-Álvarez A,Ramos-Mora A,Alonso-Cortés D,Jiménez-Ferrer JE,Huerta-Reyes ME,Tortoriello J

更新日期：2011-07-01 00:00:00

abstract：:Chemical investigation of the stems of Casearia velutina led to the isolation and structural elucidation of three new acylated glycosides, casearicosides A-C (1-3), together with 13 known compounds. The structures of the new compounds were established by spectroscopic and chemical methods. These isolates were evaluate...

journal_title：Planta medica

authors： Chai XY,Li FF,Bai CC,Xu ZR,Shi HM,Tu PF

更新日期：2010-01-01 00:00:00

abstract：:Myrrh is the oleo-gum resin of mainly Commiphora molmol and as a powdered substance, one compound in the traditional medicinal product Myrrhinil-Intest®, which has been used for the treatment of unspecific, inflammatory intestinal disorders. The aim of the present study was to evaluate the antispasmodic effect of myrr...

journal_title：Planta medica

authors： Vissiennon C,Goos KH,Goos O,Nieber K

更新日期：2015-01-01 00:00:00

abstract：:Six pentacyclic triterpenic acid methyl esters have been isolated from the methylated ethyl acetate extract of the trunk wood of MUSANGA CECROPIOIDES, as well as a triterpene saponin of the same group. One of them, cecropic acid methyl ester, is new. The structures of these compounds have been established from interpr...

journal_title：Planta medica

authors： Lontsi D,Sondengam BL,Ayafor JF,Tsoupras MG,Tabacchi R

更新日期：1990-06-01 00:00:00

abstract：:Based on the fact that Synadenium grantii is used in folk medicine for the treatment of peptic ulcers and inflammatory diseases, this work describes its chemical and pharmacological properties. Pharmacological investigation of the crude bark extract showed a high antioxidant activity over several scavenger systems, su...

journal_title：Planta medica

authors： Munhoz AC,Minozzo BR,Cruz LS,Oliveira TL,Machado WM,Pereira AV,Fernandes D,Manente FA,Vellosa JC,Nepel A,Barison A,Beltrame FL

更新日期：2014-04-01 00:00:00

abstract：:Eight iridoid glucosides have been isolated from Euphrasia rostkoviana by the combination of open column- and high performance liquid chromatography. The structure of a new compound, named eurostoside, and the identity of the others have been established by chemical transformations and spectral evidence of the compoun...

journal_title：Planta medica

authors： Salama O,Sticher O

更新日期：1983-02-01 00:00:00

abstract：:Ginkgetin, a biflavone isolated from Ginkgo biloba leaves, was previously reported as an inhibitor of group II phospholipase A2. In this study, ginkgetin was evaluated for in vivo antiarthritic and analgesic activities. Ginkgetin (10-20 mg/kg/day) strongly reduced arthritic inflammation in an animal model of rat adjuv...

journal_title：Planta medica

authors： Kim HK,Son KH,Chang HW,Kang SS,Kim HP

更新日期：1999-06-01 00:00:00

abstract：:From the methanolic extract of the whole plants of Bidens pilosa the new beta-D-glucopyranosyloxy-3-hydroxy-6(E)-tetradecen-8, 10,12-triyne besides a known polyine has been isolated and identified mainly by IR and NMR methods. The new compound showed overgrowing action against normal and transformed human cell lines i...

journal_title：Planta medica

authors： Alvarez L,Marquina S,Villarreal ML,Alonso D,Aranda E,Delgado G

更新日期：1996-08-01 00:00:00

abstract：:Reinvestigating the constituents of the roots of Vitis thunbergii Sieb. & Zucc. led to the isolation of three new resveratrol derivatives, vitisinols E-G (1-3), together with 14 known compounds. The structures of compounds 1-3 were established by application of spectroscopic analyses (NMR, MS, UV, and IR). ...

journal_title：Planta medica

authors： Chiou WF,Shen CC,Chen CC,Lin CH,Huang YL

更新日期：2009-06-01 00:00:00

abstract：:A novel hasubanalactam alkaloid, named glabradine, has been isolated from the tubers of Stephania glabra, together with three known quaternary protoberberine alkaloids, palmatine, dehydrocorydalmine and stepharanine. The structure of glabradine was assigned as 7-O-demethyl-N,O-dimethyloxostephinine, by means of rigoro...

journal_title：Planta medica

authors： Semwal DK,Rawat U

更新日期：2009-03-01 00:00:00

abstract：:The fruits of OSTEOPHLOEUM PLATYSPERMUM (Myristicaceae) contain sitosterol, eperu-8(20),13-dien-3alpha,15-diol, glyceryl laurodimyristate, glyceryl 1,3-lauromyristate and five neolignans: dihydroguaiaretic acid, hydroxyotobain, hydroxyoxootobain, guaiacin and otobaphenol. ...

journal_title：Planta medica

authors： Fo RB,de Carvalho MG,Gottlieb OR

更新日期：1984-02-01 00:00:00

abstract：:The indole alkaloid content of RAUWOLFIA SERPENTINA roots from regenerated plants (from stem-and root-callus) was compared with the parental stock. Although the total alkaloid content seems to be slightly higher in the roots from regenerated plants, HPLC-analysis of individual alkaloids indicated that the contents of ...

journal_title：Planta medica

authors： Ruyter CM,Akram M,Illahi I,Stöckigt J

更新日期：1991-08-01 00:00:00

abstract：:Aerial parts of Pterocaulon polystachyum from Chaco province, Argentina, afforded the known coumarins ayapin, isoscopoletin, prenyletin, prenyletin methyl ether, virgatenol, obtusinin, 5-methoxy-6,7-methylenedioxycoumarin, 5-(3,3-dimethylallyloxy)-6,7-methylenedioxycoumarin, 5-(2',3'-dihydroxy-3-methylbutanoxy)-6,7-me...

journal_title：Planta medica

authors： Vera N,Bardón A,Catalán CA,Gedris TE,Herz W

更新日期：2001-10-01 00:00:00