Torilin from Torilis japonica, as a new inhibitor of testosterone 5 alpha-reductase.

abstract：:From the defatted seeds of Cassia marginata fam (Caesalpinaceae) two new anthraquinone glycosides have been isolated and characterised as physcion-8-O-alpha-L-xylopyranoside and emodin-8-O-alpha-L-arabinopyranoside. ...

journal_title：Planta medica

authors： Duggal JK,Misra K

更新日期：1982-05-01 00:00:00

abstract：:Ligusticum canbyi (J.M. Coult & Rose) is a medicinal understory forest species used in traditional rituals and ceremonies for spiritual enlightenment and improved mental health. Very little is known about the phytochemical complexity or diversity of L. canbyi tissues or extracts. The current study was undertaken to de...

journal_title：Planta medica

authors： Turi CE,Murch SJ

更新日期：2013-09-01 00:00:00

abstract：:A series of mainly marine derived natural products were tested for their activities against Mycobacterium tuberculosis and M. avium. Of the thirty-nine compounds tested fifteen demonstrated minimum inhibition concentrations (MICs) of 32 micrograms/ml or less, and eleven had MICs of 16 micrograms/ml or less. The most a...

journal_title：Planta medica

authors： König GM,Wright AD,Franzblau SG

更新日期：2000-05-01 00:00:00

abstract：:Epilobium sp. are commonly used in traditional medicine in the treatment of early stages of benign prostatic hyperplasia and inflammation. It is suggested that a dominating constituent, oenothein B, is responsible for the extracts therapeutic effects. Several bioactivities were established for extracts and oenothein B...

journal_title：Planta medica

authors： Piwowarski JP,Bobrowska-Korczak B,Stanisławska I,Bielecki W,Wrzesien R,Granica S,Krupa K,Kiss AK

更新日期：2017-10-01 00:00:00

abstract：:An analytical method using HPLC with UV detection was developed to investigate the quassinoid content of Eurycoma longifolia Jack (Simaroubaceae) collected from various sources. Eurycomanone (1), longilactone (2), 14,15beta-dihydroxyklaineanone (3), 15beta-acetyl-14-hydroxyklaineanone (4), 6alpha-hydroxyeurycomalacton...

journal_title：Planta medica

authors： Chan KL,Choo CY,Morita H,Itokawa H

更新日期：1998-12-01 00:00:00

abstract：:Three new tetrahydroprotoberberine N-oxide alkaloids, (-)- cis-corydalmine N-oxide, (-)- trans-corydalmine N-oxide, and (-)- trans-isocorypalmine N-oxide, along with three known benzo[ C]phenanthridine alkaloids, norsanguinarine, dihydrosanguinarine, and oxysanguinarine, six known berberine alkaloids, (-)-tetrahydropa...

journal_title：Planta medica

authors： Chen JJ,Duh CY,Chen IS

更新日期：1999-10-01 00:00:00

abstract：:Usnic acid, a lichen secondary metabolite produced by a whole number of lichens, has attracted the interest of researchers owing to its broad range of biological activity, including antiviral, antibiotic, anticancer properties, and it possessing a certain toxicity. The synthesis of new usnic acid derivatives and the i...

journal_title：Planta medica

authors： Dyrkheeva N,Luzina O,Filimonov A,Zakharova O,Ilina E,Zakharenko A,Kuprushkin M,Nilov D,Gushchina I,Švedas V,Salakhutdinov N,Lavrik O

更新日期：2019-01-01 00:00:00

abstract：:Cell Suspension cultures of THAMNOSMA MONTANA were grown in Gamborg B5 medium which was best suited for acridone alkaloid formation. From the lyophilized cell material nine acridones and three acridone-monoglucosides have been isolated which were found for the first time in the genus THAMNOSMA. Moreover, N-methylacrid...

journal_title：Planta medica

authors： Baumert A,Maier W,Matern U,Schmidt J,Schumann B,Gröger D

更新日期：1994-04-01 00:00:00

abstract：:Many herbs, and recently their biomass from in vitro cultures, are essential for the treatment of diseases. The aim of this study was to determine the optimal growth of Bacopa monnieri (water hyssop) in an in vitro culture and to examine if extracts of the B. monnieri biomass from the in vitro culture would affect hyd...

journal_title：Planta medica

authors： Łojewski M,Pomierny B,Muszyńska B,Krzyżanowska W,Budziszewska B,Szewczyk A

更新日期：2016-02-01 00:00:00

abstract：:Several synthetic aromatase inhibitors are currently in clinical use for the treatment of postmenopausal women with hormone-receptor positive breast cancer. However, these treatments may lead to untoward side effects and so the search for new aromatase inhibitors continues, especially those for which the activity is p...

journal_title：Planta medica

authors： Balunas MJ,Kinghorn AD

更新日期：2010-08-01 00:00:00

abstract：:Three steroidal saponins, including astrogorgiosides A (1) and B (2) bearing acetamido-glucose moieties, and astrogorgioside C (3) with a 19-nor and bearing an aromatized B ring steroid aglycone, together with a known major saponin dimorphoside A (4), were obtained from the gorgonian Astrogorgia dumbea collected near ...

journal_title：Planta medica

authors： Lu YN,Cui P,Tian XQ,Lou LG,Fan CQ

更新日期：2016-06-01 00:00:00

abstract：:Synthetic butylidenephthalide (Bdph), 60 mg/kg per os (p.o.) given 3 h prior to injection of pituitrin (4 U/kg, i.v.), significantly prevented T-wave lowering on lead II electrocardiograph in unanesthetized rats. The effective dose, 60 mg/kg, was about 1/56th of the median lethal dose (LD50, p.o.) in rats. However, Bd...

journal_title：Planta medica

authors： Ko WC,Sheu JR,Tzeng SH,Chen CM

更新日期：1998-04-01 00:00:00

abstract：:Two indole alkaloids were isolated from the culture of Aspergillus fumigatus (strain No. CY018), an endophytic fungus harboring inside the elder leaf of Cynodon dactylon. These two chemicals were identified as fumigaclavine C and fumitremorgin C. In screening the bioactivity of these two indole alkaloids, their vasore...

journal_title：Planta medica

authors： Ma HY,Song YC,Mao YY,Jiang JH,Tan RX,Luo L

更新日期：2006-04-01 00:00:00

abstract：:This study was carried out to examine the potential beneficial effect of cordycepin on the decline of testicular function induced with age. A total of 30 male Sprague-Dawley rats (twenty-four 12-month-olds and six 2-month-olds) were divided into five groups. The young control (YC) and middle-aged control (MC) groups r...

journal_title：Planta medica

authors： Sohn SH,Lee SC,Hwang SY,Kim SW,Kim IW,Ye MB,Kim SK

更新日期：2012-10-01 00:00:00

abstract：:The present study investigated the role of adenosine in the stimulatory action of paeoniflorin on in vitro glucose transport. Paeoniflorin increased the uptake of a radiolabeled, non-metabolizable glucose derivative into isolated white adipocytes of Wistar rat in a concentration-dependent manner and this action was ab...

journal_title：Planta medica

authors： Tang LM,Liu IM,Cheng JT

更新日期：2003-04-01 00:00:00

abstract：:A new indole alkaloid, galanthindole, was isolated from Galanthus plicatus ssp. byzantinus (Amaryllidaceae), a plant native to northwestern Turkey. Incorporating a non-fused indole ring, galanthindole may represent the prototype of a new subgroup of the Amaryllidaceae alkaloids. Two other bases, (+)-11-hydroxyvittatin...

journal_title：Planta medica

authors： Unver N,Kaya GI,Werner C,Verpoorte R,Gözler B

更新日期：2003-09-01 00:00:00

abstract：:HPLC determinations of the aescin contents in calli and embryoids from leaf explants of AESCULUS HIPPOCASTANUM L. were carried out in order to determine whether it was possible to obtain aescin-forming proliferations IN VITRO. The results indicate that embryogenic calli and embryoids derived from them produce an amoun...

journal_title：Planta medica

authors： Profumo P,Caviglia AM,Gastaldo P,Dameri RM

更新日期：1991-02-01 00:00:00

abstract：:Immune complex binding to macrophages was enhanced by treatment with an E. kansui extract. Systematic fractionation of the extract led to the characterization of 3-O-(2'E,4'Z-decadienoyl)- and 3-O-(2,3-dimethylbutyryl)-13- O-n-dodecanoyl-13-hydroxyingenol as the active principles. Immune complex binding to macrophages...

journal_title：Planta medica

authors： Matsumoto T,Cyong JC,Yamada H

更新日期：1992-06-01 00:00:00

abstract：:A micellar electrokinetic capillary chromatography (MEKC) method for the determination of xanthyletin and xanthoxyletin in the roots bark of three Citrus plants was developed for the first time. The electrophoresis buffer was 10 mmol/L sodium borate containing 50 mmol/L sodium dodecyl sulfate, 20% (v/v) acetonitrile a...

journal_title：Planta medica

authors： Wang SF,Ju Y,Chen XG,Hu ZD

更新日期：2003-05-01 00:00:00

abstract：:A cytotoxic compound was purified from the root of Angelica gigas Nakai by normal phase HPLC. As a result of the structure analysis by mass, IR, 1H-NMR, and 13C-NMR spectrometry, the compound was identified as decursinol angelate, a structural isomer of decursin, and characterized originally from Sesei grandivittatum....

journal_title：Planta medica

authors： Ahn KS,Sim WS,Lee IK,Seu YB,Kim IH

更新日期：1997-08-01 00:00:00

abstract：:Three new glycosides, 1,4,8-trihydroxynaphthalene-1-O-D-glucopyranosyl-(1-->6)-beta-D- xylopyranoside (1), 1,4,8-trihydroxynaphthalene-1-O-beta-D-glucopyranosyl-(1-->6)-alph a-L- arabinopyranoside (2), 1-hydroxy-4-methoxynaphthalene-1-O-beta-D-glucopyranosyl-(1-->6)- alpha-L-rhamnopyranoside (3), were isolated from th...

journal_title：Planta medica

authors： Lee SW,Lee KS,Son JK

更新日期：2000-03-01 00:00:00

abstract：:Medicinal herbs are increasingly used in the search for safe and efficient drug candidates for hepatitis C virus infection. In this study, we have investigated the anti-HCV effect of compounds from Mori Cortex Radicis. During a screening for extracts with anti-HCV affinity from medicinal plants (173 species), the meth...

journal_title：Planta medica

authors： Lee HY,Yum JH,Rho YK,Oh SJ,Choi HS,Chang HB,Choi DH,Leem MJ,Choi EJ,Ryu JM,Hwang SB

更新日期：2007-11-01 00:00:00

abstract：:Alpinia galanga, or galangal, has been a popular condiment used in Thai and Asian cuisine for many years. However, relatively little is known of the potential beneficial or adverse health effects of this spice. This study was conducted to analyze the capacity of galangal extract to induce cytotoxicity and DNA damage i...

journal_title：Planta medica

authors： Muangnoi P,Lu M,Lee J,Thepouyporn A,Mirzayans R,Le XC,Weinfeld M,Changbumrung S

更新日期：2007-07-01 00:00:00

abstract：:The absolute stereostructure of a novel skeletal diterpene, standishinal (1), from the bark of Thuja standishii was confirmed by X-ray crystallographic analyses of 1 and its p-bromobenzoate derivative. Aromatase inhibitory activities of standishinal, eight known diterpenes, totarol, 12-methoxyabieta-8,11,13-trien-11-o...

journal_title：Planta medica

authors： Minami T,Iwamoto M,Ohtsu H,Ohishi H,Tanaka R,Yoshitake A

更新日期：2002-08-01 00:00:00

abstract：:Raspberry ketone (RK) is a natural phenolic compound of the red raspberry. The dietary administration of RK to male mice has been reported to prevent high-fat diet-induced elevation in body weight and to increase lipolysis in white adipocytes. To elucidate a possible mechanism for the antiobesity action of RK, its eff...

journal_title：Planta medica

authors： Park KS

更新日期：2010-10-01 00:00:00

abstract：:A novel stilbene glucoside was isolated from the root bark of Morus alba L. (Moraceae), along with mulberroside A, cis-mulberroside A, oxyresveratrol. The structure of the novel stilbene glucoside was determined as oxyresveratrol 3'-O-beta-glucopyranoside. ...

journal_title：Planta medica

authors： Qiu F,Komatsu K,Kawasaki K,Saito K,Yao X,Kano Y

更新日期：1996-12-01 00:00:00

abstract：:The antihyperglycemic action of andrographolide, an active principle in the leaves of Andrographis paniculata (Burm. f.) Nees, was investigated in streptozotocin-induced diabetic rats (STZ-diabetic rats). Oral treatment of andrographolide decreased the plasma glucose concentrations of STZ-diabetic rats in a dose-depen...

journal_title：Planta medica

authors： Yu BC,Hung CR,Chen WC,Cheng JT

更新日期：2003-12-01 00:00:00

abstract：:The medicinal plants, Coutarea latiflora Sesse & Moc. ex. DC. (Hintonia latiflora Bullock) (Rubiaceae) and Exostema caribaeum (Jacq.) Roem. et Schult. (Rubiaceae) were examined for antimalarial properties. Among different crude solvent extracts of the stem bark, the hydrolysed ethyl acetate extracts were shown to have...

journal_title：Planta medica

authors： Noster S,Kraus L

更新日期：1990-02-01 00:00:00

abstract：:Herbal medicine has been used to treat diseases for centuries; however, the biological active components and the mechanistic understanding of actions of plant-derived drugs are permanently discussed. MicroRNAs are a class of small, non-coding RNAs that play crucial roles as regulators of gene expression. In recent yea...

journal_title：Planta medica

authors： Xie W,Weng A,Melzig MF

更新日期：2016-08-01 00:00:00

abstract：:Four new neolignan glucosides, longiflorosides A, B, C and D, in addition to one known neolignan glucoside, dehydro-diconiferyl alcohol-4-O-beta-D-glucopyranoside were obtained from whole plants of Pedicularis longiflora. The structures of these compounds were determined mainly on spectral evidence. ...

journal_title：Planta medica

authors： Wang CZ,Jia ZJ

更新日期：1997-06-01 00:00:00