New nervogenic acid derivatives from Liparis nervosa.

abstract：:A new resveratrol dimer, (+)-vitisinol E (1) which demonstrated inhibitory activity on BACE-1 (beta-site APP-cleaving enzyme 1) in vitro, was isolated from the stembark extract of Vitis vinifera (Vitaceae) together with four known resveratrol oligomers, (+)-epsilon-viniferin (2), (+)-ampelopsin A (3), (+)-vitisin A (4...

journal_title：Planta medica

authors： Choi YH,Yoo MY,Choi CW,Cha MR,Yon GH,Kwon DY,Kim YS,Park WK,Ryu SY

更新日期：2009-04-01 00:00:00

abstract：:Dihydrogoniothalamin is a styrylpyrone isolated from the leaves of Aniba panurensis. The present work aimed at investigating the vasorelaxant activity of dihydrogoniothalamin and its underlying mechanism of action in the rat aorta. Dihydrogoniothalamin (0.01-100 µM) induced a concentration-dependent vasodilatation of ...

journal_title：Planta medica

authors： Rezende BA,Silva GC,Corradi RG,Teles MM,Barbosa-Filho JM,Lemos VS,Cortes SF

更新日期：2015-10-01 00:00:00

abstract：:A total of 37 commercial samples of Ginseng Radix, the origins of which belonged to Panax ginseng C. A. Meyer, P. quinquefolia Linn. (American ginseng), and P. notoginseng Burkill (sanchi-ginseng), respectively, were collected from the Taiwan herbal markets. The contents of nine ginsenosides, Rb(1), Rb(2), Rc, Rd, Re,...

journal_title：Planta medica

authors： Chuang WC,Wu HK,Sheu SJ,Chiou SH,Chang HC,Chen YP

更新日期：1995-10-01 00:00:00

abstract：:Blood fluke of the genus Schistosoma are the etiological agents of human schistosomiasis, an important neglected tropical disease that afflicts over 200 million people worldwide. The treatment for this disease relies heavily on a single drug, praziquantel. Recent reports of praziquantel resistance raise concerns about...

journal_title：Planta medica

authors： Moraes Jd,Almeida AA,Brito MR,Marques TH,Lima TC,Sousa DP,Nakano E,Mendonça RZ,Freitas RM

更新日期：2013-03-01 00:00:00

abstract：:Matrine and arsenic trioxide are monomers used in traditional Chinese medicine possessing anti-myeloma activities. In this study, we evaluated the effects and mechanisms of matrine, arsenic trioxide, and their combination therapy on the proliferation and apoptosis of the myeloma cell lines RPMI8226 and U266. The effec...

journal_title：Planta medica

authors： Yu Q,Chen B,Zhang X,Qian W,Ye B,Zhou Y

更新日期：2013-06-01 00:00:00

abstract：:Aquaticol, an unusual bis-sesquiterpene was isolated from the medicinal plant Veronica anagallis-aquatica, in addition to 11 known compounds, aucubin, geniposidic acid, mussaenoside, catalposide, verproside, amphicoside, catalpol, boschnaloside, shanzhiside methyl ester, sitosterol and beta-stigmast-4-en-6 beta-ol-3-o...

journal_title：Planta medica

authors： Su BN,Yang L,Gao K,Jia ZJ

更新日期：2000-04-01 00:00:00

abstract：:Indole alkaloid contents were investigated in leaves of Tabernaemontana pachysiphon (Apocynaceae) trees in the natural habitat, Shimba Hills National Reserve, Kenya. The contents of the major alkaloids apparicine, tubotaiwine, tubotaiwine- N-oxide, and isovoacangine varied with site, leaf age, leaf growth form, positi...

journal_title：Planta medica

authors： Höft M,Verpoorte R,Beck E

更新日期：1998-03-01 00:00:00

abstract：:Healing of predominantly metaphyseal fractures in postmenopausal osteoporosis is delayed and comparatively poor. Hormone replacement therapy could improve fracture healing, but, because of its potential side effects, natural alternatives are more appealing. The aim of this study was to determine if the soy metabolite ...

journal_title：Planta medica

authors： Kolios L,Sehmisch S,Daub F,Rack T,Tezval M,Stuermer KM,Stuermer EK

更新日期：2009-04-01 00:00:00

abstract：:A novel hasubanalactam alkaloid, named glabradine, has been isolated from the tubers of Stephania glabra, together with three known quaternary protoberberine alkaloids, palmatine, dehydrocorydalmine and stepharanine. The structure of glabradine was assigned as 7-O-demethyl-N,O-dimethyloxostephinine, by means of rigoro...

journal_title：Planta medica

authors： Semwal DK,Rawat U

更新日期：2009-03-01 00:00:00

abstract：:Urinary metabolites of scutellarin, the main effective constituent of breviscapine, a cerebrovascular and cardiovascular drug consisting of total flavonoids of Erigeron breviscapus, were investigated in rats. Two major metabolites were isolated from the urine of rats following oral administration of scutellarin and id...

journal_title：Planta medica

authors： Qiu F,Xia H,Zhang T,Di X,Qu G,Yao X

更新日期：2007-04-01 00:00:00

abstract：:Two new secodammarane triterpenoid saponins were isolated from the leaves of Cyclocarya paliurus. Based on chemical and spectral analysis they were assigned as (20S)-20-hydroxy-24-O-alpha-L-arabino-pyranosyl-3,4- secodammar-4(28),11,25-trien-3-oic acid, named cyclocarioside II and 25-hydroxy-(20S,24R)-epoxy-12R-O-beta...

journal_title：Planta medica

authors： Shu RG,Xu CR,Li LN,Yu ZL

更新日期：1995-12-01 00:00:00

abstract：:The inhibitory effect of flavonoids and phenolic acids, which could be transformed from flavonoids by human intestinal microflora, on the growth of Helicobacter pylori (HP) was investigated. Ponciretin, hesperetin, naringenin and diosmetin were active against HP. Among them, ponciretin was the most potent and its MIC ...

journal_title：Planta medica

authors： Bae EA,Han MJ,Kim DH

更新日期：1999-06-01 00:00:00

abstract：:Bioassay-guided fractionation of the anti-HIV-1 active EtOAc extract from leaves and twigs of Ochna integerrima led to the isolation of five new flavonoid glycosides 1 - 5, five known flavonoids 6 - 10, and two known flavonoid glycosides 11 and 12. Structures were determined based on spectroscopic analyses. 6- gamma, ...

journal_title：Planta medica

authors： Reutrakul V,Ningnuek N,Pohmakotr M,Yoosook C,Napaswad C,Kasisit J,Santisuk T,Tuchinda P

更新日期：2007-06-01 00:00:00

abstract：:Teak ( Tectona grandis L.f., Verbenaceae) sawdust extract inhibited the growth of Aspergillus niger. Centrifugal partition chromatography was used to isolate the active compounds. By (1)H-NMR the active compounds were identified as deoxylapachol and tectoquinone. Two A. niger transgenic strains which show induction of...

journal_title：Planta medica

authors： Sumthong P,Damveld RA,Choi YH,Arentshorst M,Ram AF,van den Hondel CA,Verpoorte R

更新日期：2006-08-01 00:00:00

abstract：:Chemical investigation of the EtOH extract of Morus alba L. (Moraceae), as guided by free radical scavenging activity, furnished 5,7-dihydroxycoumarin 7-methyl ether (1), two prenylflavones, cudraflavone B (2) and cudraflavone C (3), and oxyresveratrol (4). Compounds 1 and 4 showed superoxide scavenging effects with t...

journal_title：Planta medica

authors： Oh H,Ko EK,Jun JY,Oh MH,Park SU,Kang KH,Lee HS,Kim YC

更新日期：2002-10-01 00:00:00

abstract：:EGFR, as a critical signaling pathway in many human tumors, has become an important target of cancer drug design. Taspine has shown meaningful angiogenesis activity in previous studies. This paper is to investigate the antitumor action of taspine by modulating the EGFR signaling pathway. The study determined the expre...

journal_title：Planta medica

authors： Zhang Y,Zheng L,Zhang J,Dai B,Wang N,Chen Y,He L

更新日期：2011-11-01 00:00:00

abstract：:Two new anthraquinones have been isolated from the seeds of PEGANUM HARMALA Linn and the structures established as 3,6-dihydroxy-8-methoxy-2-methylanthraquinone (peganone; 1) and 8-hydroxy-7-methoxy-2-methylanthraquinone (peganone; 2) by spectral correlations and chemical evidences. ...

journal_title：Planta medica

authors： Pitre S,Srivastava SK

更新日期：1987-02-01 00:00:00

abstract：:Besides the known pyrrolidine alkaloids ruspolinone ( 1), norruspolinone ( 2), and norruspoline ( 3) the "bispyrrolidine" alkaloid hypercratine was isolated from the roots of RUSPOLIA HYPERCRATERIFORMIS M. R. (Acanthaceae). After chemical and spectroscopic analysis of the new compound, structure 4 is suggested. ...

journal_title：Planta medica

authors： Neukomm G,Roessler F,Johne S,Hesse M

更新日期：1983-08-01 00:00:00

abstract：:Three new sauchinone analogues, sauchinones B-D (1-3), together with sauchinone (4), were isolated from the aerial part of Saururus chinensis. Structures of the new compounds were determined by extensive spectroscopic data as well as X-ray analysis. Compounds 3 and 4 inhibited nitric oxide production in lipopolysaccha...

journal_title：Planta medica

authors： Gao X,He J,Wu XD,Peng LY,Dong LB,Deng X,Li Y,Cheng X,Zhao QS

更新日期：2013-12-01 00:00:00

abstract：:The inhibition of butyrylcholinesterase activity in human serum by protoberberine, benzophenanthridine and aporphine alkaloids as well as four model compounds has been studied. The mechanism of the inhibition is discussed on the basis of the different types of interaction of these compounds with butyrylcholinesterase ...

journal_title：Planta medica

authors： Ulrichová J,Walterová D,Preininger V,Simánek V

更新日期：1983-07-01 00:00:00

abstract：:Many herbs, and recently their biomass from in vitro cultures, are essential for the treatment of diseases. The aim of this study was to determine the optimal growth of Bacopa monnieri (water hyssop) in an in vitro culture and to examine if extracts of the B. monnieri biomass from the in vitro culture would affect hyd...

journal_title：Planta medica

authors： Łojewski M,Pomierny B,Muszyńska B,Krzyżanowska W,Budziszewska B,Szewczyk A

更新日期：2016-02-01 00:00:00

abstract：:In our ongoing research into anti-inflammatory compounds from Tanacetum microphyllum, four naturally occurring flavonoids (santin, ermanin, centaureidin and 5,3'-dihydroxy-4'-methoxy-7-methoxycarbonylflavonol) and one sesquiterpene lactone (hydroxyachillin) isolated from this plant, were evaluated as potential inhibit...

journal_title：Planta medica

authors： Abad MJ,Bermejo P,Alvarez M,Guerra JA,Silván AM,Villar AM

更新日期：2004-01-01 00:00:00

abstract：:The inhibitory activity of stilbenes isolated from medicinal plants on cell adhesion molecules on the surface of THP-1 human monocytic cell lines was investigated. Among ten stilbenes tested, four stilbenes displayed a significant inhibitory activity on the expression of both intercellular adhesion molecule-1 (ICAM-1)...

journal_title：Planta medica

authors： Ahn KS,Kim JH,Oh SR,Ryu SY,Lee HK

更新日期：2000-10-01 00:00:00

abstract：:New protostane-type triterpenes, 11-deoxyalisol C and alisol D, have been isolated from the rhizomes of ALISMA PLANTAGO-AQUATICA, and their structures have been elucidated on the basis of spectral and chemical data. ...

journal_title：Planta medica

authors： Fukuyama Y,Pei-Wu G,Rei W,Yamada T,Nakagawa K

更新日期：1988-10-01 00:00:00

abstract：:Anti-sera against a complement-activating pectin (AR-2IIb), which was purified from the roots of Angelica acutiloba Kitagawa, were obtained by immunization of rabbits, and a polyclonal anti-AR-2IIb antibody of the IgG class was purified by affinity chromatography on AR-2IIb-immobilized Sepharose and Protein G-Sepharos...

journal_title：Planta medica

authors： Wang NL,Kiyohara H,Matsumoto T,Otsuka H,Hirano M,Yamada H

更新日期：1994-10-01 00:00:00

abstract：:Myrrh is the oleo-gum resin of mainly Commiphora molmol and as a powdered substance, one compound in the traditional medicinal product Myrrhinil-Intest®, which has been used for the treatment of unspecific, inflammatory intestinal disorders. The aim of the present study was to evaluate the antispasmodic effect of myrr...

journal_title：Planta medica

authors： Vissiennon C,Goos KH,Goos O,Nieber K

更新日期：2015-01-01 00:00:00

abstract：:The acylphloroglucinol derivative hyperforin is a major constituent of St. John's wort extracts ( Hypericum perforatum L.), which has been demonstrated to contribute to the antidepressant action of this herbal drug. In previous investigations we observed that hyperforin causes a rapid stimulation of intracellular calc...

journal_title：Planta medica

authors： Schrattenholz A,Schroer K,Chatterjee SS,Koch E

更新日期：2004-04-01 00:00:00

abstract：:Olive oil has been shown to exhibit beneficial effects in the prevention of cardiovascular diseases although its molecular mechanism still remains unclear. In the present study, we investigated the effect of hydroxytyrosol (HT), a major phenolic component in olive oil and leaves from OLEA EUROPAEA L. (Oleaceae family...

journal_title：Planta medica

authors： Zrelli H,Matsuka M,Araki M,Zarrouk M,Miyazaki H

更新日期：2011-10-01 00:00:00

abstract：:3beta-Acetoxy-17beta-hydroxy-androst-5-ene was isolated from aerial parts of Acacia nilotica (L.) Willd (Mimosaceae). The structure of this compound was established by spectral analysis and single crystal X-ray diffraction analysis. The steroid showed dose-dependent anti-inflammatory activity against TPA-induced mouse...

journal_title：Planta medica

authors： Chaubal R,Mujumdar AM,Puranik VG,Deshpande VH,Deshpande NR

更新日期：2003-03-01 00:00:00

abstract：:Extracts from Pygeum africanum, Serenoa repens and Cucurbita pepo are used in the treatment of benign prostatic hyperplasia (BPH) and prostate cancer (PCa). The activity of the androgen receptor (AR) is known to control growth of the prostate. Here, we examined extracts of these plants for their antiandrogenic activit...

journal_title：Planta medica

authors： Schleich S,Papaioannou M,Baniahmad A,Matusch R

更新日期：2006-07-01 00:00:00