Abstract:
:3beta-Acetoxy-17beta-hydroxy-androst-5-ene was isolated from aerial parts of Acacia nilotica (L.) Willd (Mimosaceae). The structure of this compound was established by spectral analysis and single crystal X-ray diffraction analysis. The steroid showed dose-dependent anti-inflammatory activity against TPA-induced mouse earedema.
journal_name
Planta Medjournal_title
Planta medicaauthors
Chaubal R,Mujumdar AM,Puranik VG,Deshpande VH,Deshpande NRdoi
10.1055/s-2003-38482subject
Has Abstractpub_date
2003-03-01 00:00:00pages
287-8issue
3eissn
0032-0943issn
1439-0221journal_volume
69pub_type
信件相关文献
PLANTA MEDICA文献大全abstract::We previously reported the isolation of eleven new cardiac glycosides called cheiranthosides I-XI together with two known ones (olitoriside and erysimoside) from the seeds of Erysimum cheiranthoides L. The glycosides were evaluated for their inhibitory activity against Na+,K(+)-ATPase by comparing with typical cardiac...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2001-14309
更新日期:2001-06-01 00:00:00
abstract::High molecular compounds from Chinese herbal medicines, including ribosome-inactivating proteins and polysaccharides from both fungi and high plants have been tested for the treatment of malignant diseases. Polysaccharides possessing immunostimulating activities can be used as adjuvants in tumor treatment. The fungi c...
journal_title:Planta medica
pub_type: 杂志文章,评审
doi:10.1055/s-2003-38494
更新日期:2003-03-01 00:00:00
abstract::The antimycobacterial quinolones 1-methyl-2-undecyl-4-quinolone, dihydroevocarpine and evocarpine as well as the indoloquinazoline alkaloids rutaecarpine and evodiamine - all from the Chinese medicinal herb Evodia rutaecarpa - were tested in two in vitro assays, for cytotoxicity and interaction with p-glycoprotein (p-...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-993743
更新日期:2007-12-01 00:00:00
abstract::The essential oil composition of three Zingiberaceae widely used as medicinal aromatic plants from S. Tomé and Príncipe: Aframomum danielli (Hook. f.) K. Schum., Curcuma longa L. and Zingiber officinale Rosc. was studied. Two samples of the essential oils from fruit of A. danielli and from rhizomes of the other two sp...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2001-16494
更新日期:2001-08-01 00:00:00
abstract::Menopause is characterized by deep metabolic disturbances, including decreased insulin sensitivity, adiposity, and changes in lipid profiles. Estrogen replacement therapy can partially reverse these changes, and while it is safe in most healthy postmenopausal women, there are still existing concerns regarding an incre...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/a-0835-6622
更新日期:2019-04-01 00:00:00
abstract::Thirty-five flavonoids of seven different types, namely isoflavonoids, chalcones, dihydroflavonols, flavanols, flavanones, flavones, and flavonols were investigated for their ability to inhibit ascorbate-induced microsomal lipid peroxidation and their cytotoxicity. For each activity a structure-activity relationship w...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2001-16472
更新日期:2001-08-01 00:00:00
abstract::Evidence is presented for the structure of a new limonoid, amoorinin, from the stem bark of AMOORA ROHITUKA on the basis of spectral and chemical evidences. ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-962715
更新日期:1987-06-01 00:00:00
abstract::Five new compounds, including one new xanthone, 1-hydroxy-5-methoxyxanthone 6-O-β-D-glucopyranoside (1), one new lignan, 3-(β-D-glucopyranosyloxymethyl)-2-(4-hydroxy-3-methoxyphenyl)-5-(3-acetoxypropyl)-7-methoxy-(2R,3S)-dihydrobenzofuran (2), and three new γ-pyrones, japonicumone A 4'-O-β-D-glucopyranoside (3), japon...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0032-1328538
更新日期:2013-05-01 00:00:00
abstract::Bioassay-guided isolation of two new compounds, 3,4-methylenedioxy-3'-O-methyl-4'-O-glucoside ellagic acid (1) and the pteleoellagic acid derivative (2), from the stem bark of Pteleopsis hylodendron is reported along with 3,4-methylenedioxy-3'-O-methyl ellagic acid (3), 3,3'-di-O-methyl ellagic acid (4) and 3,3',4'-tr...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2001-14306
更新日期:2001-06-01 00:00:00
abstract::Electrospray ionization mass spectrometry (ESI-MS) combined with multiple tandem mass spectrometry (MS (n)) has been applied for simultaneously determining lipo-alkaloids from the aconite tubers. ESI-MS can give a very good mass separation for lipo-alkaloid mixture and MS (n) can provide structural information. Accord...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-1999-14086
更新日期:1999-06-01 00:00:00
abstract::We aimed to find antiallergic agents from natural sources using mast cells activated during allergic reaction. We screened over 2000 plants for blockade of histamine release and identified two of them, S. baicalenesis and P. edulis. Bioassay-guided fractionation led to two main constituent flavonoids, baicalin from S....
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0029-1240649
更新日期:2010-05-01 00:00:00
abstract::The neuroprotective effects of spiramine T, an atisine-type diterpenoid alkaloid isolated from the Chinese herbal medicine Spiraea japonica var. acuta (Rosaceaee), on cerebral ischemia-reperfusion injury produced by 10-min bilateral occlusion of the common carotid arteries followed by 5-day reperfusion in gerbils were...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2001-11510
更新日期:2001-03-01 00:00:00
abstract::In the present study, we demonstrate that saucernetin-8 ( 1) and saucernetin-7 ( 2), isolated from the underground parts of Saururus chinensis (Saururaceae), exerted potent inhibitory effects on LPS-induced nitric oxide (NO) and prostaglandin E (2) (PGE (2)) production in RAW 264.7 cells. Both compounds 1 and 2, known...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2003-45106
更新日期:2003-10-01 00:00:00
abstract::Some enzymes of the terminal steps of phenylalanine and tyrosine biosyntheses were investigated in various alkaloid-forming ergot strains. All strains studied utilize both arogenate and phenylpyruvate as an intermediate in L-phenylalanine synthesis. L-Tyrosine is preferentially or exclusively synthesized via the aroge...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-969195
更新日期:1986-10-01 00:00:00
abstract::The methanolic extract of the fruits of Torilis japonica showed a potent inhibition against 5 alpha-reductase activity in vitro. Bioassay-guided fractionation of the methanol extract of the fruits followed by repeated silica gel chromatography led to the isolation of an active principle and its structure was identifie...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2003-39717
更新日期:2003-05-01 00:00:00
abstract::The effects of phytoestrogens on the female breast are discussed controversially. On the one hand, epidemiological and experimental data provide evidence that dietary phytoestrogens may prevent the development of breast cancer. On the other hand, in breast cancer cell lines and tumour models isoflavone phytoestrogens ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2005-916229
更新日期:2006-03-01 00:00:00
abstract::Four antiplatelet components were isolated from Arnebia euchroma. They inhibited the aggregation of washed rabbit platelets caused by collagen, arachidonic acid, platelet-activating factor, ADP, or thrombin. The potency of inhibiting collagen-induced platelet aggregation is in the following order: acetylshikonin (IC50...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-959718
更新日期:1993-10-01 00:00:00
abstract::The chloroform extract of Valeriana officinalis led to the isolation of clionasterol-3-O-beta-D-glucopyranoside and a mixture of 6'-O-acyl-beta-D-glucosyl-clionasterols. The acyl moieties were identified as hexadecanoyl, 8 E,11 E-octadecadienoyl and 14-methylpentadecanoyl by alkaline hydrolysis followed by GC-MS analy...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2005-864179
更新日期:2005-10-01 00:00:00
abstract::We report the effects of a fraction (F1) obtained from Himanthalia elongata on spontaneous locomotor activity, hypermotility, motor coordination, rectal temperature, pentobarbitone-induced hypnosis, pentylenetetrazole-induced convulsions and analgesic activity in the writhing and hot-plate tests. This fraction caused ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-959655
更新日期:1993-06-01 00:00:00
abstract::A contribution of the volatile oil from ginger rhizomes (Zingiber officinale Roscoe) on inhabiting the 5-HT3 receptor complex had been shown. In the present study a possible interaction of some compounds of the volatile oil with the 5-HT3 receptor system expressed in N1E-115 cells and with the serotoninergic system of...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-967171
更新日期:2007-04-01 00:00:00
abstract::A new indole alkaloid, galanthindole, was isolated from Galanthus plicatus ssp. byzantinus (Amaryllidaceae), a plant native to northwestern Turkey. Incorporating a non-fused indole ring, galanthindole may represent the prototype of a new subgroup of the Amaryllidaceae alkaloids. Two other bases, (+)-11-hydroxyvittatin...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2003-43206
更新日期:2003-09-01 00:00:00
abstract::A callus culture of Aleurites fordii Hemsley (Euphorbiaceae) producing five galloylglucoses and an ellagitannin, geraniin, was established. The production of pentagalloylglucose was remarkably enhanced under light irradiation compared with that in the dark. Cell growth and tannin production were also greatly affected ...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2002-36348
更新日期:2002-12-01 00:00:00
abstract::This perspective describes some commonly used animal models for the evaluation of potential chemopreventive agents in colon carcinogenesis. Special emphasis is given to the azoxymethane (AOM)/1,2-dimethylhydrazine (DMH) rat model and APCMIN mice, carrying a mutation in APC, a key gene in human carcinogenesis. In the A...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2008-1074577
更新日期:2008-10-01 00:00:00
abstract::Olive oil has been shown to exhibit beneficial effects in the prevention of cardiovascular diseases although its molecular mechanism still remains unclear. In the present study, we investigated the effect of hydroxytyrosol (HT), a major phenolic component in olive oil and leaves from OLEA EUROPAEA L. (Oleaceae family...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0030-1271073
更新日期:2011-10-01 00:00:00
abstract::The oligomeric stilbenes (+)-alpha-viniferin (1), miyabenol C (2), and kobophenol A (3) have been isolated from Caragana sinica (Buchoz) Rehd (Leguminosae). (+)-alpha-Viniferin (1) and miyabenol C (2) exhibited protein kinase C inhibitory activity at low micromolar concentrations. (+)-alpha-Viniferin inhibited keratin...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957996
更新日期:1995-02-01 00:00:00
abstract::A new isoquinoline alkaloid (6), along with nine known ones (1-5, 7-10), was isolated from the plateau plant Corydalis hendersonii, which is used as a traditional Tibetan medicine. The structure of the new compound was elucidated as 9-methyldecumbenine C by spectroscopic evidence. ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0029-1185331
更新日期:2009-04-01 00:00:00
abstract::Five known abietane diterpenes, fatty acid esters of 7alpha-acyloxy-6beta-hydroxyroyleanone (1), grandidone A (2), 7alpha-acetoxy-6beta-hydroxyroyleanone (3), 6beta,7alpha-dihydroxyroyleanone (4), and coleon U (5), isolated from Plectranthus grandidentatus Gürke, were evaluated for their in vitro antiproliferative act...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2002-34407
更新日期:2002-09-01 00:00:00
abstract::Phytochemical investigation of the dichloromethane extract of the leaves of Peltophorum pterocarpum, a tropical ornamental tree, led to the isolation of twelve compounds (1-12). One new derivative of peltogynoid ophioglonin (1) and a new 2-phenoxychromone (2) with its 3'-O-β-D-glucoside derivative (3) are described he...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0032-1328299
更新日期:2013-04-01 00:00:00
abstract::The therapy of type-2 diabetes mellitus is one of the major challenges of our age. A possible strategy to prevent the progression of this disease is the inhibition of protein tyrosine phosphatase 1B (PTP1B), a major negative regulator in the insulin and leptin signalling pathway. Phellodendri amurensis cortex is a wel...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0031-1280377
更新日期:2012-02-01 00:00:00
abstract::The cytotoxicity of goniothalamin was found to be strong towards both cancerous (HGC-27, MCF-7, PANC-1, HeLa), and non-cancerous (3T3) cell lines, especially in cases of dividing cells. Drug exposure studies indicated that the cytotoxic action of goniothalamin was time- and dose-dependent. At the ultrastructural level...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957611
更新日期:1997-02-01 00:00:00