Abstract:
:The chloroform extract of Valeriana officinalis led to the isolation of clionasterol-3-O-beta-D-glucopyranoside and a mixture of 6'-O-acyl-beta-D-glucosyl-clionasterols. The acyl moieties were identified as hexadecanoyl, 8 E,11 E-octadecadienoyl and 14-methylpentadecanoyl by alkaline hydrolysis followed by GC-MS analysis. The isolated compounds did not exhibit any anti-inflammatory, anticancer or cytotoxic activity when tested in a variety of in vitro cell-based assays.
journal_name
Planta Medjournal_title
Planta medicaauthors
Pullela SV,Choi YW,Khan SI,Khan IAdoi
10.1055/s-2005-864179subject
Has Abstractpub_date
2005-10-01 00:00:00pages
960-1issue
10eissn
0032-0943issn
1439-0221journal_volume
71pub_type
杂志文章相关文献
PLANTA MEDICA文献大全abstract::Activity-guided fractionation of the dichloromethane extract from leaves of Piper fulvescens, using an agar overlay bioautographic method, led to the isolation of three antifungal neolignans identified as conocarpan, eupomatenoid 5 and eupomatenoid 6. The minimal inhibitory concentration of these three neolignans agai...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2001-18838
更新日期:2001-12-01 00:00:00
abstract::Three new compounds, 15-acetoxy-12-hydroxy-16-methyl-labda-8(17),13E-diene (1), ent-labda-8(17),13-dien-15,16-olid-19-oic acid methyl ester (2), and 12-hydroxy-labda-8(17),13-dien-15,16-olide (3), together with two known compounds, 19-acetoxy-ent-labda-8(17),13-dien-15,16-olide (4), and 16-acetoxy-12,15-epoxy-15beta-h...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-967170
更新日期:2007-05-01 00:00:00
abstract::A phytochemical study of the whole plant of TEPHROSIA HAMILTONII afforded a new flavonoid, characterised as 5, 7-dimethoxy-8-(2, 3-epoxy-3-methylbutyl)-flavanone, along with other known compounds. ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-962679
更新日期:1987-04-01 00:00:00
abstract::The preventive effects of hydroxychalcone derivatives on ulcer formation induced by severe necrotizing agents such as 60% ethanol in 150 mM HCl (HCl-ethanol) and 0.2 N NaOH in rats were examined. Among the compounds tested, 2',4'-dihydroxychalcone gave the strongest activity in both experimental models and protected t...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-961498
更新日期:1992-10-01 00:00:00
abstract::Two new naphtho-pyrone glycosides, 9-[(beta-D-glucopyranosyl-(1----6)-O-beta-D-glucopyranosyl)oxy]-10- hydroxy-7-methoxy-3-methyl-1H-naphtho[2,3-c]pyran-1 -one (5) and 6-[(alpha-apiofuranosyl-(1----6)-O-beta-D-glucopyranosyl)oxy]- rubrofusarin (6), together with cassiaside (3) and rubrofusarin-6-beta-gentiobioside (4)...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-962003
更新日期:1989-06-01 00:00:00
abstract::Urinary metabolites of scutellarin, the main effective constituent of breviscapine, a cerebrovascular and cardiovascular drug consisting of total flavonoids of Erigeron breviscapus, were investigated in rats. Two major metabolites were isolated from the urine of rats following oral administration of scutellarin and id...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-967128
更新日期:2007-04-01 00:00:00
abstract::A reinvestigation of the aerial parts of TEUCRIUM SCORDIUM afforded in addition to several known diterpenes five new clerodane derivatives, all closely related to teucrin. The structures and the stereochemistry were elucidated by high resolution (1)H-NMR spectroscopy. ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-969508
更新日期:1985-08-01 00:00:00
abstract::The roots of HAPLOPAPPUS FREEMONTII afforded in addition to the known 8-oxo-beta-cyperone two further derivatives. The structures were elucidated by highfield (1)H-NMR spectroscopy. ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-969205
更新日期:1986-10-01 00:00:00
abstract::In addition to 7-methoxy-2-methyl-3,4,5-trihydroxyanthraquinone (1), physcion (2), macrosporin (3), deoxybostrycin (4), altersolanol B (5) and dactylariol (6), a new hexahydroanthraquinone named pleospdione (7) was isolated from the culture of Pleospora sp . IFB-E006, an endophytic fungus residing in the normal stem o...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2005-864190
更新日期:2005-11-01 00:00:00
abstract::In natural product research, the isolation of biomarkers or bioactive compounds from complex natural extracts represents an essential step for de novo identification and bioactivity assessment. When pure natural products have to be obtained in milligram quantities, the chromatographic steps are generally labourious an...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0035-1545912
更新日期:2015-11-01 00:00:00
abstract::Geraniol dehydrogenase, the specific enzyme involved in geraniol to citral TRANS (geranial) transformation, activity was monitored in various lemongrass cultivars differing in amounts and relative percentages of citral and geraniol in their essential oils. The enzyme activity had a positive and significant association...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-959636
更新日期:1993-04-01 00:00:00
abstract::Andrographolide (Andro) is a potentially anti-inflammatory diterpenoid lactone isolated from the traditional herbal medicine ANDROGRAPHIS PANICULATA, which has been effectively used for the treatment of infection, inflammation, cold, fever and diarrhea in China for centuries. In the current study, we found that Andro ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-990230
更新日期:2007-10-01 00:00:00
abstract::The effects of phytoestrogens on the female breast are discussed controversially. On the one hand, epidemiological and experimental data provide evidence that dietary phytoestrogens may prevent the development of breast cancer. On the other hand, in breast cancer cell lines and tumour models isoflavone phytoestrogens ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2005-916229
更新日期:2006-03-01 00:00:00
abstract::From the fresh rhizomes of Tamus communis five phenanthrenes (1 - 5) were isolated under the guidance of cytotoxic assays in HeLa cells. The compounds were obtained from the highly active CHCl (3) fraction of the MeOH extract by using multistep chromatographic purifications, including VLC, preparative TLC, HPLC and ge...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-941505
更新日期:2006-06-01 00:00:00
abstract::Angelicae Sinensis Radix is commonly used in traditional Chinese medicine. Pharmacological studies show that Angelicae Sinensis Radix has clear anticoagulant activity. Therefore, in this study, the anticoagulant activity of crude Angelicae Sinensis Radix extracts was investigated by measuring the thrombin times of the...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0035-1558309
更新日期:2016-03-01 00:00:00
abstract::In previous studies, crude Houttuynia cordata polysaccharides showed beneficial effects on acute lung injury in vivo, a syndrome in which anti-complementary activities played an important role. Anti-complementary activity-guided fractionation of H. cordata polysaccharides led to the isolation of two highly branched ho...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/a-0955-7841
更新日期:2019-09-01 00:00:00
abstract::Both borneol and menthol are bioactive substances derived from Chinese herbal medicines. In order to understand the pharmacokinetics of borneol and menthol in Qingyan drop pills, a rapid, sensitive, and simple gas chromatographic (GC) method with flame ionization detection (FID) was developed for the simultaneous dete...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0030-1270998
更新日期:2011-09-01 00:00:00
abstract::The effects of the essential oil of Mentha pulegium L. (EOMP), a plant commonly known as "pennyroyal" or "poejo" that is used in folk medicine as an abortifaceant, were assessed on the isolated rat myometrium. Myometrial strips were stimulated with 10 nM oxytocin or 10 microM PGF (2alpha). EOMP (10 - 300 microg/mL) co...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2005-837819
更新日期:2005-03-01 00:00:00
abstract::Eleven sesquiterpenoids have been isolated from the whole plants of Youngia japonica (Asteraceae). Among these sesquiterpenoids, five were identified as new compounds on the basis of spectroscopic methods and chemical analysis. Their structures were 3-oxo-8alpha-(4-hydoxyphenyl)acetoxy-10(14),11(13)-guaiadien-12,6-oli...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2005-916182
更新日期:2006-02-01 00:00:00
abstract::Variability in the oil content in natural populations of Cymbopogon jawarancusa is discussed. Races rich in piperitone, phellandrene and other chemical constituents have been identified. The oil producing ability was largely genetic and showed heritability of 79.0 percent. ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-971731
更新日期:1981-04-01 00:00:00
abstract::In this study, the significant hepatoprotective effect of dioscin against CCl₄-induced acute liver damage in mice was first discovered, and the effect produced by dioscin at the dose of 100 mg/kg was equal to the action produced by silymarin at the dose of 200 mg/kg. Then, 1-dimension gel electrophoresis was used to s...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0030-1250461
更新日期:2011-03-01 00:00:00
abstract::A crude polysaccharide fraction (DAP-1) was prepared from roots of Dipsacus asperoides by hot water extraction and EtOH precipitation, and tested for anti-complementary activity, mitogenic activity of lymphocytes, and effects on acid phosphatase and phagocytic activities of macrophages. DAP-1 showed not only anti-comp...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957720
更新日期:1997-10-01 00:00:00
abstract::Antroquinonol ( 1), an ubiquinone derivative, was isolated from the solid-state fermented mycelium of Antrodia camphorata (Polyporaceae, Aphyllophorales), a parasitic fungus indigenous to Taiwan. The structure of compound 1 was elucidated by the analysis of their spectroscopic data. Its cytotoxic activities were evalu...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-990232
更新日期:2007-10-01 00:00:00
abstract::Tuberculosis is the main cause of death from a single infectious agent. Globally, according to the World Health Organization, in 2018, there were an estimated 1.2 million tuberculosis deaths. Moreover, there is a continuous appearance of drug-resistant strains. Thus, development of new antituberculosis medicines shoul...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/a-1157-1732
更新日期:2020-05-11 00:00:00
abstract::Matrine and arsenic trioxide are monomers used in traditional Chinese medicine possessing anti-myeloma activities. In this study, we evaluated the effects and mechanisms of matrine, arsenic trioxide, and their combination therapy on the proliferation and apoptosis of the myeloma cell lines RPMI8226 and U266. The effec...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0032-1328554
更新日期:2013-06-01 00:00:00
abstract::Bioassay-guided isolation of two new compounds, 3,4-methylenedioxy-3'-O-methyl-4'-O-glucoside ellagic acid (1) and the pteleoellagic acid derivative (2), from the stem bark of Pteleopsis hylodendron is reported along with 3,4-methylenedioxy-3'-O-methyl ellagic acid (3), 3,3'-di-O-methyl ellagic acid (4) and 3,3',4'-tr...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2001-14306
更新日期:2001-06-01 00:00:00
abstract::The present study is aimed at evaluating the effects of luteolin on the scratching behavior associated with an allergic cutaneous reaction in mice. Elicitation of passive cutaneous anaphylaxis, and intradermal injections of compound 48/80, histamine or serotonin induced scratching behavior in ICR mice. Models of irrit...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2005-864137
更新日期:2005-05-01 00:00:00
abstract::Flavonolignan compounds have been isolated from the fruits of SILYBUM MARIANUM subsp. ANATOLICUM and kaempferol 3-sulphate and other flavonoid compounds have been isolated from the aerial parts and were identified. The flavonoid sulphate derivatives are shown to be present in SILYBUM genus for the first time. ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-962330
更新日期:1988-02-01 00:00:00
abstract::Purification of a cytotoxic crude alkaloid extract of Cassytha filiformis led to the isolation of four known aporphine alkaloids: neolitsine, dicentrine, cassythine (= cassyfiline) and actinodaphnine. Their structures were determined by analysis of spectroscopic data. All isolated alkaloids were tested for their cytot...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2002-35651
更新日期:2002-11-01 00:00:00
abstract::The dietary intake of flavonoids seems to be inversely related to cardiovascular mortality. The consumption of isoflavonoids is increasing in the general population, especially due to the use of food supplements and a variety of isoflavonoid-rich foods. However, detailed studies on the vascular influence of individual...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/a-1158-9422
更新日期:2020-07-01 00:00:00