Equol but not genistein improves early metaphyseal fracture healing in osteoporotic rats.

abstract：:A new eudesmanolide sesquiterpene, sivasinolide 6-O-angelate (1), was isolated from the aerial parts of Anthemis ruthenica together with the known compounds chrysanin (2), tanacin (3), 3 beta-hydroxycostunolide (4), centauridin (5), and centaureidin (6). The compounds were obtained by means of bioactivity-guided fract...

journal_title：Planta medica

authors： Hajdú Z,Zupkó I,Réthy B,Forgo P,Hohmann J

更新日期：2010-01-01 00:00:00

abstract：:Nine isoflavonoids including a new pterocarpene, puemiricarpene, were isolated from the tuberous root of Pueraria mirifica (Leguminosae). The structure of puemiricarpene was determined by spectroscopic means. Estrogenic activity of the isolated isoflavonoids was tested using MCF-7 human breast cancer cells. Moderate a...

journal_title：Planta medica

authors： Chansakaow S,Ishikawa T,Sekine K,Okada M,Higuchi Y,Kudo M,Chaichantipyuth C

更新日期：2000-08-01 00:00:00

abstract：:We have identified kamebakaurin as an inhibitor of NF-KB and elucidated its molecular mechanism as a specific inhibitor in the DNA-binding activity of the p50 subunit of NF-KB. Here, we describe its anti-inflammatory activity in in vitro and in vivo models. Kamebakaurin dose-dependently inhibited not only the expressi...

journal_title：Planta medica

authors： Lee JH,Choi JK,Noh MS,Hwang BY,Hong YS,Lee JJ

更新日期：2004-06-01 00:00:00

abstract：:The olive (Olea europaea) leaf is considered an important traditional herbal medicine utilized against infectious diseases, and for the treatment of diabetes and hypertension. Moreover, olive leaf constituents have been related to cardioprotection, probably due to their association with cellular redox modulating effec...

journal_title：Planta medica

authors： Efentakis P,Iliodromitis EK,Mikros E,Papachristodoulou A,Dagres N,Skaltsounis AL,Andreadou I

更新日期：2015-06-01 00:00:00

abstract：:Two new naphtho-pyrone glycosides, 9-[(beta-D-glucopyranosyl-(1----6)-O-beta-D-glucopyranosyl)oxy]-10- hydroxy-7-methoxy-3-methyl-1H-naphtho[2,3-c]pyran-1 -one (5) and 6-[(alpha-apiofuranosyl-(1----6)-O-beta-D-glucopyranosyl)oxy]- rubrofusarin (6), together with cassiaside (3) and rubrofusarin-6-beta-gentiobioside (4)...

journal_title：Planta medica

authors： Wong SM,Wong MM,Seligmann O,Wagner H

更新日期：1989-06-01 00:00:00

abstract：:A new resveratrol dimer, (+)-vitisinol E (1) which demonstrated inhibitory activity on BACE-1 (beta-site APP-cleaving enzyme 1) in vitro, was isolated from the stembark extract of Vitis vinifera (Vitaceae) together with four known resveratrol oligomers, (+)-epsilon-viniferin (2), (+)-ampelopsin A (3), (+)-vitisin A (4...

journal_title：Planta medica

authors： Choi YH,Yoo MY,Choi CW,Cha MR,Yon GH,Kwon DY,Kim YS,Park WK,Ryu SY

更新日期：2009-04-01 00:00:00

abstract：:The fruit of Ziziphus jujuba Mill., known as jujube or Chinese date, is commonly consumed as health supplement or herbal medicine worldwide. To study the beneficial role of jujube in enhancing hematopoietic function, we investigated its roles on the expression of erythropoietin in cultured Hep3B human hepatocellular c...

journal_title：Planta medica

authors： Chen J,Lam CT,Kong AY,Zhang WL,Zhan JY,Bi CW,Chan GK,Lam KY,Yao P,Dong TT,Tsim KW

更新日期：2014-11-01 00:00:00

abstract：:This study demonstrated that plant extracts containing acetylenic isobutylamides and polyacetylenes, previously reported as occurring in Echinacea, have phototoxic antimicrobial activity against fungi, including clinically relevant pathogenic fungi. Results show that hexane extracts of Echinacea variably inhibit growt...

journal_title：Planta medica

authors： Binns SE,Purgina B,Bergeron C,Smith ML,Ball L,Baum BR,Arnason JT

更新日期：2000-04-01 00:00:00

abstract：:The inhibitory action of the major constituent of Genista tridentata L. (Papilionaceae), 4',5,7-trihydroxyisoflavone (genistein), on contractions induced by agonists and electrical field stimulation of smooth muscle was analysed. Genistein inhibited twitches evoked by electrical-stimulation of strips of guinea-pig ile...

journal_title：Planta medica

authors： Herrera MD,Marhuenda E,Gibson A

更新日期：1992-08-01 00:00:00

abstract：:A phytochemical investigation of the whole plants of Cassia occidentalis led to the isolation of two new cycloartane triterpenoids, cycloccidentalic acids A and B (1 and 2), and five new related saponins, cycloccidentalisides I-V (3-7), together with sixteen known compounds. The structures of the isolated compounds we...

journal_title：Planta medica

authors： Li SF,Di YT,Luo RH,Zheng YT,Wang YH,Fang X,Zhang Y,Li L,He HP,Li SL,Hao XJ

更新日期：2012-05-01 00:00:00

abstract：:Andrographolide (Andro) is a potentially anti-inflammatory diterpenoid lactone isolated from the traditional herbal medicine ANDROGRAPHIS PANICULATA, which has been effectively used for the treatment of infection, inflammation, cold, fever and diarrhea in China for centuries. In the current study, we found that Andro ...

journal_title：Planta medica

authors： Ji L,Liu T,Liu J,Chen Y,Wang Z

更新日期：2007-10-01 00:00:00

abstract：:Variability in the oil content in natural populations of Cymbopogon jawarancusa is discussed. Races rich in piperitone, phellandrene and other chemical constituents have been identified. The oil producing ability was largely genetic and showed heritability of 79.0 percent. ...

journal_title：Planta medica

authors： Dhar AK,Thappa RK,Atal CK

更新日期：1981-04-01 00:00:00

abstract：:Transient receptor potential channels and cannabinoid receptors are deputed to the regulation of sensory, homeostatic, and inflammatory events in the human organism. Therefore, their modulation promises to have relevant applications in important therapeutic areas such as inflammation, pain, and cancer. This review sum...

journal_title：Planta medica

authors： Rigano D,Formisano C,Taglialatela-Scafati O

更新日期：2016-06-01 00:00:00

abstract：:Many compounds of plant origin have been identified that inhibit different stages in the replication cycle of human immunodeficiency virus (HIV): 1) virus adsorption: chromone alkaloids (schumannificine), isoquinoline alkaloids (michellamines), sulphated polysaccharides and polyphenolics, flavonoids, coumarins (glycoc...

journal_title：Planta medica

authors： Vlietinck AJ,De Bruyne T,Apers S,Pieters LA

更新日期：1998-03-01 00:00:00

abstract：:We previously reported that total coumarins, the major active components of Urtica dentata Hand, exhibited substantial protection against the development of autoimmune diabetes. Diabetic nephropathy is one of the most serious complications of diabetes and is closely correlated with end-stage renal disease. We used the...

journal_title：Planta medica

authors： Cao H,Ji Y,Li W,Liu Y,Fu R,Xiang M

更新日期：2015-10-01 00:00:00

abstract：:HPLC determinations of the aescin contents in calli and embryoids from leaf explants of AESCULUS HIPPOCASTANUM L. were carried out in order to determine whether it was possible to obtain aescin-forming proliferations IN VITRO. The results indicate that embryogenic calli and embryoids derived from them produce an amoun...

journal_title：Planta medica

authors： Profumo P,Caviglia AM,Gastaldo P,Dameri RM

更新日期：1991-02-01 00:00:00

abstract：:This paper reports the phytochemical investigation of the 50% aq. EtOH extract of Houttuynia cordata, an effective TCM and functional food in China, which led to the isolation of 17 flavonoids including four new ones. The four new compounds were flavonoid derivatives tethered with houttuynin (3-oxododecanal). Each of ...

journal_title：Planta medica

authors： Chen SD,Li T,Gao H,Zhu QC,Lu CJ,Wu HL,Peng T,Yao XS

更新日期：2013-12-01 00:00:00

abstract：:The distribution and level of yew constituents vary with species and tissues. In this study, a rapid and valid method incorporating ultra-fast liquid chromatography (UFLC) with MS and UV detection was developed for simultaneous determination of paclitaxel and its six semisynthesis precursors in needles and hair roots ...

journal_title：Planta medica

authors： Ge GB,Liang SC,Hu Y,Liu XB,Mao YX,Zhang YY,Luan HW,Qiu MH,Yang L

更新日期：2010-10-01 00:00:00

abstract：:Some enzymes of the terminal steps of phenylalanine and tyrosine biosyntheses were investigated in various alkaloid-forming ergot strains. All strains studied utilize both arogenate and phenylpyruvate as an intermediate in L-phenylalanine synthesis. L-Tyrosine is preferentially or exclusively synthesized via the aroge...

journal_title：Planta medica

authors： Schmauder HP,Gröger D

更新日期：1986-10-01 00:00:00

abstract：:The effect of nitrogen and carbon sources on growth and diosgenin production was studied with Dioscorea deltoidea cells which were grown under defined conditions in a chemostat, and transferred to batch cultures. Both ammonium and nitrate nitrogen were required for growth and steroid production; diosgenin production w...

journal_title：Planta medica

authors： Tal B,Gressel J,Goldberg I

更新日期：1982-02-01 00:00:00

abstract：:From the fresh, undried, and uncrushed leaves of NERIUM OLEANDER a new triterpenoid, kanerocin, has been isolated along with known ursolic and oleanolic acids and its structure established through chemical and spectroscopic methods as 3alpha-hydroxy-urs-18,20-dien-28-oic acid. ...

journal_title：Planta medica

authors： Siddiqui S,Siddiqui BS,Begum S,Hafeez F

更新日期：1989-06-01 00:00:00

abstract：:Two triterpenoidal saponins having phytolaccagenin as the aglycone were isolated from the roots of Phytolacca esculenta (Phytolaccaceae). The structures of two new saponins, esculentoside I and esculentoside N, were established to be 3-O-[beta-D-glucopyranosyl-(1----4)-beta-D- glucopyranosyl]-28-O-beta-D-glucopyranosy...

journal_title：Planta medica

authors： Yi YH

更新日期：1992-02-01 00:00:00

abstract：:The aerial parts of CUNILA SPICATA Benth., a Brasilian Lamiaceae, afforded a sesquiterpene-aldehyde named isocaryophyllen-13-al (beta-betulenal) ( 1). The constitution and configuration of this compound were established by high field NMR-techniques for the first time. ...

journal_title：Planta medica

authors： Manns D,Hartmann R

更新日期：1992-10-01 00:00:00

abstract：:Activity-guided fractionation of the dichloromethane extract from leaves of Piper fulvescens, using an agar overlay bioautographic method, led to the isolation of three antifungal neolignans identified as conocarpan, eupomatenoid 5 and eupomatenoid 6. The minimal inhibitory concentration of these three neolignans agai...

journal_title：Planta medica

authors： Freixa B,Vila R,Ferro EA,Adzet T,Cañigueral S

更新日期：2001-12-01 00:00:00

abstract：:The mechanism of action, leakage of cytochrome c from mitochondria into cytosol, for the antineoplastic compound glyfoline was examined. Additionally, our current studies revealed that glyfoline induced apoptotic changes and arrested cell cycle procession at the G2/M phase in nasopharyngeal carcinoma (NPC). A reverse ...

journal_title：Planta medica

authors： Su TL,Huang HM,Wang CK,Wu HC,Lin CT

更新日期：2005-01-01 00:00:00

abstract：:Rice bran, a by-product of brown rice milling, is a rich source of dietary fiber and protein, and its usage as a functional food is expected to increase. In this study, immunomodulatory effects of glycoprotein obtained from rice bran were studied in normal mice and mouse models of cyclophosphamide-induced immunosuppre...

journal_title：Planta medica

authors： Park HY,Yu AR,Hong HD,Kim HH,Lee KW,Choi HD

更新日期：2016-05-01 00:00:00

abstract：:Electrospray ionization mass spectrometry (ESI-MS) combined with multiple tandem mass spectrometry (MS (n)) has been applied for simultaneously determining lipo-alkaloids from the aconite tubers. ESI-MS can give a very good mass separation for lipo-alkaloid mixture and MS (n) can provide structural information. Accord...

journal_title：Planta medica

authors： Sun W,Song F,Cui M,Liu S

更新日期：1999-06-01 00:00:00

abstract：:Anti-sera against a complement-activating pectin (AR-2IIb), which was purified from the roots of Angelica acutiloba Kitagawa, were obtained by immunization of rabbits, and a polyclonal anti-AR-2IIb antibody of the IgG class was purified by affinity chromatography on AR-2IIb-immobilized Sepharose and Protein G-Sepharos...

journal_title：Planta medica

authors： Wang NL,Kiyohara H,Matsumoto T,Otsuka H,Hirano M,Yamada H

更新日期：1994-10-01 00:00:00

abstract：:Two new sesquiterpenes, (E)-(2S,3S,6R)-atlantone-2,3-diol (1) and (E)-(2S,3S,6S)-atlantone-2,3,6-triol (2), along with two known sesquiterpenes, atlantolone (3) and (E)-α-atlantone (4), were isolated from Cedrus deodara Loud. The structures of the new compounds were elucidated on the basis of UV, IR, NMR, HR‑ESI-QTOF‑...

journal_title：Planta medica

authors： Chaudhary A,Sood S,Kaur P,Kumar N,Thakur A,Gulati A,Singh B

更新日期：2012-01-01 00:00:00

abstract：:Sangre de Grado extract used by Peruvian natives as a cicatrizant agent, was collected from trees of the species Croton lechleri growing in the Peruvian jungle. The Sangre de Grado was found to contain one alkaloid identified as taspine and which was shown to be the active cicatrizant principle by an in vivo test in m...

journal_title：Planta medica

authors： Vaisberg AJ,Milla M,Planas MC,Cordova JL,de Agusti ER,Ferreyra R,Mustiga MC,Carlin L,Hammond GB

更新日期：1989-04-01 00:00:00