Tetrandrine selectively protects against amyloid-beta protein - but not against MPTP-induced cytotoxicity in SK-N-SH neuroblastoma cells.

abstract：:In this work we studied the effect of alpha-asarone, a hypolipidemic active principle of Guatteria gaumeri Greenman, on hepatic lipid metabolism using adult rat hepatocytes cultured on a feeder layer of 3T3 cells. These cultures synthesize and secrete for at least two weeks various lipids from [14C]-acetic and [14C]-o...

journal_title：Planta medica

authors： Hernández A,López ML,Chamorro G,Mendoza-Figueroa T

更新日期：1993-04-01 00:00:00

abstract：:The neuroprotective effects of spiramine T, an atisine-type diterpenoid alkaloid isolated from the Chinese herbal medicine Spiraea japonica var. acuta (Rosaceaee), on cerebral ischemia-reperfusion injury produced by 10-min bilateral occlusion of the common carotid arteries followed by 5-day reperfusion in gerbils were...

journal_title：Planta medica

authors： Li L,Nie J,Shen Z,Wu W,Chen Z,Hao X

更新日期：2001-03-01 00:00:00

abstract：:Lyophilised aqueous extract of Euphorbia hirta L. (Euphorbiaceae) has been evaluated for analgesic, antipyretic and anti-inflammatory properties in mice and rats, in order to complete its activity profile, after the confirmation of the existence of a central depressant activity particularly expressed by a strong sedat...

journal_title：Planta medica

authors： Lanhers MC,Fleurentin J,Dorfman P,Mortier F,Pelt JM

更新日期：1991-06-01 00:00:00

abstract：:The active ingredient dl-tetrahydropalmatine (THP) isolated from the traditional Chinese herb Corydalis racemosa has been found to have antihypertensive effects. However, severe cardiac and neurological toxic effects were reported from using this herb for the treatment of pain. In an isolated perfused rat heart model,...

journal_title：Planta medica

authors： Chan P,Chiu WT,Chen YJ,Wu PJ,Cheng JT

更新日期：1999-05-01 00:00:00

abstract：:Matrine and arsenic trioxide are monomers used in traditional Chinese medicine possessing anti-myeloma activities. In this study, we evaluated the effects and mechanisms of matrine, arsenic trioxide, and their combination therapy on the proliferation and apoptosis of the myeloma cell lines RPMI8226 and U266. The effec...

journal_title：Planta medica

authors： Yu Q,Chen B,Zhang X,Qian W,Ye B,Zhou Y

更新日期：2013-06-01 00:00:00

abstract：:Scutellariae Radix (SR), the root of Scutellaria baicalensis (Labiatae), is widely used in clinical Chinese medicine. In order to investigate the effect of SR on the absorption and disposition of cyclosporine, rats were administered with cyclosporine orally (in the form of the microemulsion Neoral and intravenously wi...

journal_title：Planta medica

authors： Lai MY,Hsiu SL,Hou YC,Tsai SY,Chao PD

更新日期：2004-02-01 00:00:00

abstract：:An allergenic protein from tatary buckwheat seeds, designated TBt, was purified by salting out, anion exchange chromatography and size exclusion chromatography (SEC). Analysis by sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) and SEC showed that the allergenic protein was composed of two subunits...

journal_title：Planta medica

authors： Zhang X,Cui X,Li Y,Wang Z

更新日期：2008-12-01 00:00:00

abstract：:Three new steroidal saponins were isolated from the fruits of Tribulus terrestris, and their structures were elucidated as (25R,S)-5 alpha-spirostane-12-one-3 beta-ol-3-O-beta-xylopyranosyl(1-->2)- [beta-xylopyranosyl(1-->3)]-beta-glucopyranosyl(1-->4)-[alpha-rhamno- pyranosyl(1-->2)]-beta-galactopyranoside; 26-O-beta...

journal_title：Planta medica

authors： Cai L,Wu Y,Zhang J,Pei F,Xu Y,Xie S,Xu D

更新日期：2001-03-01 00:00:00

abstract：:Amphotericin B (AmB) is a representative antibiotic for the control of serious fungal infections, and its fungicidal activity was greatly enhanced by allicin, an allyl-sulfur compound from garlic. In addition to the plasma membrane permeability change, AmB induced vacuole membrane damage so that the organelles were vi...

journal_title：Planta medica

authors： Ogita A,Fujita K,Taniguchi M,Tanaka T

更新日期：2006-10-01 00:00:00

abstract：:The dietary intake of flavonoids seems to be inversely related to cardiovascular mortality. The consumption of isoflavonoids is increasing in the general population, especially due to the use of food supplements and a variety of isoflavonoid-rich foods. However, detailed studies on the vascular influence of individual...

journal_title：Planta medica

authors： Migkos T,Pourová J,Vopršalová M,Auger C,Schini-Kerth V,Mladěnka P

更新日期：2020-07-01 00:00:00

abstract：:Chemical studies on the constituents from the dragon's blood of Dracaena cambodiana led to the discovery of three new flavonoid derivatives (1- 3) and six known compounds (4- 9). The structures of the three new compounds were elucidated by NMR and MS spectroscopic analyses. All compounds were evaluated for their growt...

journal_title：Planta medica

authors： Luo Y,Wang H,Zhao YX,Zeng YB,Shen HY,Dai HF,Mei WL

更新日期：2011-12-01 00:00:00

abstract：:The methanolic extract of the fruits of Torilis japonica showed a potent inhibition against 5 alpha-reductase activity in vitro. Bioassay-guided fractionation of the methanol extract of the fruits followed by repeated silica gel chromatography led to the isolation of an active principle and its structure was identifie...

journal_title：Planta medica

authors： Park WS,Son ED,Nam GW,Kim SH,Noh MS,Lee BG,Jang IS,Kim SE,Lee JJ,Lee CH

更新日期：2003-05-01 00:00:00

abstract：:Variability in the oil content in natural populations of Cymbopogon jawarancusa is discussed. Races rich in piperitone, phellandrene and other chemical constituents have been identified. The oil producing ability was largely genetic and showed heritability of 79.0 percent. ...

journal_title：Planta medica

authors： Dhar AK,Thappa RK,Atal CK

更新日期：1981-04-01 00:00:00

abstract：:Some enzymes of the terminal steps of phenylalanine and tyrosine biosyntheses were investigated in various alkaloid-forming ergot strains. All strains studied utilize both arogenate and phenylpyruvate as an intermediate in L-phenylalanine synthesis. L-Tyrosine is preferentially or exclusively synthesized via the aroge...

journal_title：Planta medica

authors： Schmauder HP,Gröger D

更新日期：1986-10-01 00:00:00

abstract：:Three new guaiane-type sesquiterpene lactones (1-3), together with nine related sesquiterpenes (4-12), were isolated from the whole extract of Ixeris dentata (Asteraceae). The chemical structures of isolates 1-12 were established by spectroscopic analyses as 3 β,8 β-dihydroxy-guaia-10(14)-en-1 α,4 α,5 α,6 β,7 α,11 βH-...

journal_title：Planta medica

authors： Cha MR,Choi YH,Choi CW,Yoo DS,Kim YS,Choi SU,Kim YH,Ryu SY

更新日期：2011-03-01 00:00:00

abstract：:The essential oil obtained from the aerial parts of Phlomis lanata has been analyzed by GC/MS. 48 compounds representing 96.85% of the oil were identified; alpha-pinene, limonene and trans-caryophyllene were found as its main components. The essential all showed a moderate in vitro activity against six Gram (+/-) bact...

journal_title：Planta medica

authors： Couladis M,Tanimanidis A,Tzakou O,Chinou IB,Harvala C

更新日期：2000-10-01 00:00:00

abstract：:Protodioscin (NSC-698 796) is a furostanol saponin isolated from the rhizome of Dioscorea collettii var. hypoglauca (Dioscoreaceae), a Chinese herbal remedy for the treatment of cervical carcinoma, carcinoma of urinary bladder and renal tumor for centuries. To systematically evaluate its potential anticancer activity,...

journal_title：Planta medica

authors： Hu K,Yao X

更新日期：2002-04-01 00:00:00

abstract：:The antiinflammatory activity of borjatriol (a diterpenoid isolated from SIDERITIS MUGRONENSIS Borja) was tested using the cotton pellet-granuloma assay. The compound inhibited the granuloma weight and the serum lysozyme activity in a dose-dependently way. The determination of this enzyme has allowed us to distinguish...

journal_title：Planta medica

authors： Villar A,Salom R,Alcaraz MJ

更新日期：1984-02-01 00:00:00

abstract：:The quantification of free and total alkannins in 13 endemic Anatolian Alkanna species is described for the first time. Extraction of the samples was performed by sonication with hexane, followed by hydrolysis in 1 N NaOH. For analysis, a new HPLC method, utilizing reversed phase material (Synergi Max RP), was develop...

journal_title：Planta medica

authors： Pekin G,Ganzera M,Senol S,Bedir E,Korkmaz KS,Stuppner H

更新日期：2007-03-01 00:00:00

abstract：:Two new C(18) dibenzocyclooctadiene lignans named heteroclitalignans A and B (1 and 3), one new C(19) homolignan named heteroclitalignan C(4) and one new natural product named heteroclitalignan D(2), together with the four known lignans kadsurarin (5), kadsulignan E (6), d-epigalbacin, and meso-dihydroguaiaretic acid ...

journal_title：Planta medica

authors： Wang W,Liu J,Liu R,Xu Z,Yang M,Wang W,Liu P,Sabia G,Wang X,Guo D

更新日期：2006-02-01 00:00:00

abstract：:YANG XIN is a traditional Chinese medicine formulation used for nervous fatigue and consists of a proprietary blend of concentrated extracts from 18 plant ingredients. The 18 constituent plant ingredients, YANG XIN capsules, and formulations 2014-005_1 A and 1B were extracted by consecutive 24-hour macerations with di...

journal_title：Planta medica

authors： Almalki AJ,Zaher A,Simithy J,Keller WJ,Tripp M,Calderón AI

更新日期：2016-08-01 00:00:00

abstract：:We identified eight diterpenes from Cryptomeria japonica (Taxodiaceae), which inhibit the activity of the androgen receptor (AR) in human prostate cancer (PCa) 22Rv1-derived 103E cells. The compounds 6,12-dihydroxyabieta-5,8,11,13-tetraen-7-one ( 2), sugiol ( 3), ferruginol ( 4), and 5-epixanthoperol ( 7) have near 10...

journal_title：Planta medica

authors： Tu WC,Wang SY,Chien SC,Lin FM,Chen LR,Chiu CY,Hsiao PW

更新日期：2007-10-01 00:00:00

abstract：:The aggregation of the microtubule-associated protein tau is a significant event in many neurodegenerative diseases including Alzheimer's disease. The inhibition or reversal of tau aggregation is therefore a potential therapeutic strategy for these diseases. Fungal natural products have proven to be a rich source of u...

journal_title：Planta medica

authors： Paranjape SR,Chiang YM,Sanchez JF,Entwistle R,Wang CC,Oakley BR,Gamblin TC

更新日期：2014-01-01 00:00:00

abstract：:Two new acylated secoiridoid glycosides were isolated from the aqueous acetone extract of the whole herb of Gentiana algida. The structures of these new products were established by spectral and chemical methods as 6'-(2,3-dihydroxybenzoyl)sweroside and 6'-(2,3-dihydroxybenzoyl)swertiamarin, respectively. ...

journal_title：Planta medica

authors： Tan RX,Hu J,Dong LD,Wolfender JL,Hostettmann K

更新日期：1997-12-01 00:00:00

abstract：:Halimium halimifolium (Hh) is a shrub used in Algerian folk medicine to treat gastrointestinal pain. An UHPLC-PDA-ESI/MSn method was developed to identify the metabolic profile of the traditionally used infusion (Hh-A) from the aerial parts. The structures of flavanols were confirmed by NMR analysis after the isolatio...

journal_title：Planta medica

authors： Kerbab K,Sansone F,Zaiter L,Esposito T,Celano R,Franceschelli S,Pecoraro M,Benayache F,Rastrelli L,Picerno P,Aquino RP,Mencherini T

更新日期：2019-08-01 00:00:00

abstract：:This paper reports the phytochemical investigation of the 50% aq. EtOH extract of Houttuynia cordata, an effective TCM and functional food in China, which led to the isolation of 17 flavonoids including four new ones. The four new compounds were flavonoid derivatives tethered with houttuynin (3-oxododecanal). Each of ...

journal_title：Planta medica

authors： Chen SD,Li T,Gao H,Zhu QC,Lu CJ,Wu HL,Peng T,Yao XS

更新日期：2013-12-01 00:00:00

abstract：:The content of ursolic acid and oleanolic acid was determined in different plant parts of two Glechoma species, G. hederacea and G. hirsuta. To achieve optimal extraction conditions of ursolic acid and oleanolic acid from plant material, several methods including maceration, heat reflux, Soxhlet, and ultrasonic extrac...

journal_title：Planta medica

authors： Grabowska K,Żmudzki P,Wróbel-Biedrawa D,Podolak I

更新日期：2021-01-15 00:00:00

abstract：:Dihydrogoniothalamin is a styrylpyrone isolated from the leaves of Aniba panurensis. The present work aimed at investigating the vasorelaxant activity of dihydrogoniothalamin and its underlying mechanism of action in the rat aorta. Dihydrogoniothalamin (0.01-100 µM) induced a concentration-dependent vasodilatation of ...

journal_title：Planta medica

authors： Rezende BA,Silva GC,Corradi RG,Teles MM,Barbosa-Filho JM,Lemos VS,Cortes SF

更新日期：2015-10-01 00:00:00

abstract：:A MeOH extract prepared from culture of an actinomycete Streptomyces sp. HZP-2216E isolated from marine green algae Ulva pertusa was found to significantly inhibit proliferation of human glioma cells. Two different media were applied to culture this marine actinomycete, which produced two new compounds of 23-O-butyryl...

journal_title：Planta medica

authors： Zhang Z,Chen L,Zhang X,Liang Y,Anjum K,Chen L,Lian XY

更新日期：2017-12-01 00:00:00

abstract：:Hydroalcoholic extracts and pressed juice from Echinacea pallida were phytochemically characterised by HPLC-MS analyses. Ferulic and caffeic acid derivatives were identified as major constituents. All tested extracts and pressed juice from Echinacea pallida exhibited a low cytotoxic activity on monkey kidney cells in ...

journal_title：Planta medica

authors： Schneider S,Reichling J,Stintzing FC,Messerschmidt S,Meyer U,Schnitzler P

更新日期：2010-02-01 00:00:00