Taxol and related compounds in Korean native yews (Taxus cuspidata).

abstract：:Owing to their high content of flavonoids and saponins, plantlets of Avena sativa L. (Poaceae) are likely to possess anti-inflammatory and immunoregulatory properties of value in the treatment of atopic dermatitis (AD). With a view to its potential use in atopic subjects at risk of developing sensitisation to dietary ...

journal_title：Planta medica

authors： Mandeau A,Aries MF,Boé JF,Brenk M,Crebassa-Trigueros V,Vaissière C,Teysseyre V,Bieber T

更新日期：2011-06-01 00:00:00

abstract：:Gas chromatography-flame ionization detection (GC-FID) was used to assess the chemical profile and quantification of cannabinoids to identify the differences, if existing, in the chemical constituents of in vitro propagated plants (IVP), conventionally grown plants (VP) and indoor grown mother plants (MP-Indoor) of a ...

journal_title：Planta medica

authors： Chandra S,Lata H,Mehmedic Z,Khan IA,ElSohly MA

更新日期：2010-05-01 00:00:00

abstract：:Shoot primordia, which were able to propagate vegetatively with a very high rate and to redifferentiate easily to new plants, were induced from shoot tips of Stevia rebaudiana Bertoni on Gamborg B5 medium containing 6-benzylaminopurine (BAP) and alpha-naphthaleneacetic acid (NAA) under light. The propagation of the sh...

journal_title：Planta medica

authors： Miyagawa H,Fujioka N,Kohda H,Yamasaki K,Taniguchi K,Tanaka R

更新日期：1986-08-01 00:00:00

abstract：:N-Deacetylcolchiceine (DAC) administered i.p. to rats decreased the level of serum cholesterol and apoB. It was accompanied by the fall of HDL-C due to the decrease of both HDL subfractions HDLa and HDLb, and by a rather weaker decrease of LDL-C. The levels of serum and lipoprotein triacylglycerols were not significan...

journal_title：Planta medica

authors： Skottová N,Vecera R,Walterová D,Simánek V

更新日期：1992-02-01 00:00:00

abstract：:Pure compounds were isolated from plant extracts with antimalarial activity. The extracts were obtained from the tubers of Cyperus rotundus L. (Cyperaceae), the rootbark of Zanthoxylum gilletii (De Wild) Waterm. (Rutaceae), and the rootbark of Margaritaria discoidea (Baill.) Webster (Euphorbiaceae). The most active co...

journal_title：Planta medica

authors： Weenen H,Nkunya MH,Bray DH,Mwasumbi LB,Kinabo LS,Kilimali VA,Wijnberg JB

更新日期：1990-08-01 00:00:00

abstract：:The effect of a lignan-enriched extract of the fruits of Schisandra chinensis (FS) on hepatic glutathione (GSH) status was examined in both control and carbon tetrachloride (CCl4)-treated rats. FS treatment caused a dose-dependent enhancement in hepatic GSH status, as evidenced by significant increases in hepatic GSH ...

journal_title：Planta medica

authors： Ko KM,Ip SP,Poon MK,Wu SS,Che CT,Ng KH,Kong YC

更新日期：1995-04-01 00:00:00

abstract：:The present study investigated the role of adenosine in the stimulatory action of paeoniflorin on in vitro glucose transport. Paeoniflorin increased the uptake of a radiolabeled, non-metabolizable glucose derivative into isolated white adipocytes of Wistar rat in a concentration-dependent manner and this action was ab...

journal_title：Planta medica

authors： Tang LM,Liu IM,Cheng JT

更新日期：2003-04-01 00:00:00

abstract：:Activity-guided fractionation of the dichloromethane extract from leaves of Piper fulvescens, using an agar overlay bioautographic method, led to the isolation of three antifungal neolignans identified as conocarpan, eupomatenoid 5 and eupomatenoid 6. The minimal inhibitory concentration of these three neolignans agai...

journal_title：Planta medica

authors： Freixa B,Vila R,Ferro EA,Adzet T,Cañigueral S

更新日期：2001-12-01 00:00:00

abstract：:A lyophilised hydroalcoholic extract of Melissa officinalis L. (Lamiaceae) has been evaluated for behavioral effects in mice. According to the traditional use of M. officinalis, sedative properties have been confirmed for low doses by the decrease of behavioral parameters measured in a non-familiar environment test (s...

journal_title：Planta medica

authors： Soulimani R,Fleurentin J,Mortier F,Misslin R,Derrieu G,Pelt JM

更新日期：1991-04-01 00:00:00

abstract：:Indole alkaloid contents were investigated in leaves of Tabernaemontana pachysiphon (Apocynaceae) trees in the natural habitat, Shimba Hills National Reserve, Kenya. The contents of the major alkaloids apparicine, tubotaiwine, tubotaiwine- N-oxide, and isovoacangine varied with site, leaf age, leaf growth form, positi...

journal_title：Planta medica

authors： Höft M,Verpoorte R,Beck E

更新日期：1998-03-01 00:00:00

abstract：:In this study we investigated the effects of concomitant food intake on the bioavailability of distinct boswellic acids (BAs) from the test preparation BSE-018, a dry extract from Boswellia serrata gum resin. In a randomised, open, single-dose, two-way crossover study, healthy male subjects received three capsules of ...

journal_title：Planta medica

authors： Sterk V,Büchele B,Simmet T

更新日期：2004-12-01 00:00:00

abstract：:Quality control of drugs consists of identifying the raw material to avoid unwanted admixtures or exchange of material as well as looking for abiotic and biotic contaminations. So far, identity and microbial contamination are analyzed by separate processes and separate methods. Species identification by their DNA ("DN...

journal_title：Planta medica

authors： Schmiderer C,Lukas B,Ruzicka J,Novak J

更新日期：2018-04-01 00:00:00

abstract：:Tuberculosis, also called TB, is currently a major health hazard due to multidrug-resistant forms of bacilli. Global efforts are underway to eradicate TB using new drugs with new modes of action, higher activity, and fewer side effects in combination with vaccines. For this reason, unexplored new sources and previousl...

journal_title：Planta medica

authors： Santhosh RS,Suriyanarayanan B

更新日期：2014-01-01 00:00:00

abstract：:Ten new nervogenic acid derivatives (1-4, 6-11) and one known compound (5) have been isolated from Liparis nervosa. Their structures were determined using extensive spectroscopic analysis, including 1D and 2D NMR experiments. Compounds 3, 4, 9, 10, and 11 were evaluated for their cytotoxicity against A549, H460, Hela,...

journal_title：Planta medica

authors： Huang S,Zhou XL,Wang CJ,Wang HY,Wang YS,Shan LH,Weng J

更新日期：2013-03-01 00:00:00

abstract：:From the essential oil of Commiphora guidotti seven sesquiterpene hydrocarbons and a furanosesquiterpenoid, furanodiene, were isolated. ...

journal_title：Planta medica

authors： Craveiro A,Corsano S,Proietti G,Strappaghetti G

更新日期：1983-06-01 00:00:00

abstract：:We have identified kamebakaurin as an inhibitor of NF-KB and elucidated its molecular mechanism as a specific inhibitor in the DNA-binding activity of the p50 subunit of NF-KB. Here, we describe its anti-inflammatory activity in in vitro and in vivo models. Kamebakaurin dose-dependently inhibited not only the expressi...

journal_title：Planta medica

authors： Lee JH,Choi JK,Noh MS,Hwang BY,Hong YS,Lee JJ

更新日期：2004-06-01 00:00:00

abstract：:Tryptanthrin and (E,Z)-3-(4-hydroxy-3,5-dimethoxybenzylidene)indolinone (indolinone) were recently isolated from Isatis tinctoria as potent anti-inflammatory and antiallergic alkaloids, and shown to inhibit COX-2, 5-LOX catalyzed leukotriene synthesis, and mast cell degranulation at low µM to nM concentrations. To ass...

journal_title：Planta medica

authors： Jähne EA,Eigenmann DE,Moradi-Afrapoli F,Verjee S,Butterweck V,Hebeisen S,Hettich T,Schlotterbeck G,Smieško M,Hamburger M,Oufir M

更新日期：2016-08-01 00:00:00

abstract：:As a result of the reinvestigation of the alkaloid content of CORYDALIS BULBOSA (L.) DC. (Papaveraceae), growing in Bulgaria, a new 8,11-dioxoaporphine alkaloid, named bulbodione, together with dihydrosanguinarine, dehydroglaucine, (+/-)-sinactine, glaucinone and bicucullinine were isolated. These six alkaloids had no...

journal_title：Planta medica

authors： Kiryakov HG,Iskrenova ES

更新日期：1984-04-01 00:00:00

abstract：:The chloroform extract of the stems of Encelia ventorum yielded a new benzopyranbenzofuran dimer. The structure was assigned from (1)H-NMR and MS data as 4[2-(5-acetyl-6-hydroxybenzofuranyl)]-2-[6(7-methoxy-2, 2-dimethylbenzo-1 -pyranyl)]-pentan-2-ol. ...

journal_title：Planta medica

authors： Proksch P,Aregullin M,Rodriguez E

更新日期：1983-04-01 00:00:00

abstract：:Antioxidants such as vitamin E may act differently on skin cells depending on the age of the skin and the level of oxidative damage induced. The effects of alpha-tocopherol (ATF) on H(2)O(2)-induced DNA damage and telomere shortening of normal human skin fibroblast cells derived from young and old individual donors we...

journal_title：Planta medica

authors： Makpol S,Zainuddin A,Rahim NA,Yusof YA,Ngah WZ

更新日期：2010-06-01 00:00:00

abstract：:Investigation of Podachaenium eminens afforded nine sesquiterpene lactones (Sls) from which costunolide, 7-hydroxycostunolide, santamarin as well as 3-chlorodehydroleucodin are new for this plant and 3,4-dehydro-4-dehydroxypodachaenin (= 3-costoyloxydehydroleucodin) is found for the first time in nature. All isolated ...

journal_title：Planta medica

authors： Castro V,Murillo R,Klaas CA,Meunier C,Mora G,Pahl HL,Merfort I

更新日期：2000-10-01 00:00:00

abstract：:Epilobium sp. are commonly used in traditional medicine in the treatment of early stages of benign prostatic hyperplasia and inflammation. It is suggested that a dominating constituent, oenothein B, is responsible for the extracts therapeutic effects. Several bioactivities were established for extracts and oenothein B...

journal_title：Planta medica

authors： Piwowarski JP,Bobrowska-Korczak B,Stanisławska I,Bielecki W,Wrzesien R,Granica S,Krupa K,Kiss AK

更新日期：2017-10-01 00:00:00

abstract：:Products of lipoxygenase metabolism play a role in the pathogenesis of psoriasis. Four protoberberine alkaloids, berberine, oxyberberine, jatrorrhizine, columbamine, and two aporphine alkaloids, magnoflorine, and corytuberine, isolated from Mahonia aquifolium, were tested for lipoxygenase inhibition. Oxyberberine, cor...

journal_title：Planta medica

authors： Misík V,Bezáková L,Máleková L,Kostálová D

更新日期：1995-08-01 00:00:00

abstract：:Orosunol and 8-demethylorosunol, two new 1-aryl-2,3-naphthalide lignans, have been isolated from Justicia flava root. Structures IV and V respectively have been proposed for them by spectral (UV, IR, PMR, (13)C NMR, and MS) and chemical evidence. ...

journal_title：Planta medica

authors： Olaniyi AA

更新日期：1982-03-01 00:00:00

abstract：:Five new compounds, including one new xanthone, 1-hydroxy-5-methoxyxanthone 6-O-β-D-glucopyranoside (1), one new lignan, 3-(β-D-glucopyranosyloxymethyl)-2-(4-hydroxy-3-methoxyphenyl)-5-(3-acetoxypropyl)-7-methoxy-(2R,3S)-dihydrobenzofuran (2), and three new γ-pyrones, japonicumone A 4'-O-β-D-glucopyranoside (3), japon...

journal_title：Planta medica

authors： Zhou GS,Ma XL,Zeng KW,Tu PF,Jiang Y

更新日期：2013-05-01 00:00:00

abstract：:Nine isoflavonoids including a new pterocarpene, puemiricarpene, were isolated from the tuberous root of Pueraria mirifica (Leguminosae). The structure of puemiricarpene was determined by spectroscopic means. Estrogenic activity of the isolated isoflavonoids was tested using MCF-7 human breast cancer cells. Moderate a...

journal_title：Planta medica

authors： Chansakaow S,Ishikawa T,Sekine K,Okada M,Higuchi Y,Kudo M,Chaichantipyuth C

更新日期：2000-08-01 00:00:00

abstract：:In this study we investigate the active constituents of the rhizome of Zingiber officinale, Roscoe (ginger) and determine their activity on glucose uptake in cultured L6 myotubes and the molecular mechanism underlying this action. Freeze-dried ginger powder was extracted with ethyl acetate (1 kg/3 L) to give the total...

journal_title：Planta medica

authors： Li Y,Tran VH,Duke CC,Roufogalis BD

更新日期：2012-09-01 00:00:00

abstract：:Phytochemical studies on Galanthus species resulted in the isolation of three new compounds: 3,3'-O-(3',3''-dihydroxybutanoyl)hamayne and 11,3'-O-(3',3''-dihydroxybutanoyl)hamayne from G. nivalis and 2-O-(3'-hydroxybutanoyl)lycorine from G. elwesii. Additionally, 3,11-O-(3',3''-dihydroxybutanoyl)hamayne, 3,11,3'-O-(3'...

journal_title：Planta medica

authors： Berkov S,Cuadrado M,Osorio E,Viladomat F,Codina C,Bastida J

更新日期：2009-10-01 00:00:00

abstract：:In this study, the significant hepatoprotective effect of dioscin against CCl₄-induced acute liver damage in mice was first discovered, and the effect produced by dioscin at the dose of 100 mg/kg was equal to the action produced by silymarin at the dose of 200 mg/kg. Then, 1-dimension gel electrophoresis was used to s...

journal_title：Planta medica

authors： Lu B,Yin L,Xu L,Peng J

更新日期：2011-03-01 00:00:00

abstract：:Many compounds of plant origin have been identified that inhibit different stages in the replication cycle of human immunodeficiency virus (HIV): 1) virus adsorption: chromone alkaloids (schumannificine), isoquinoline alkaloids (michellamines), sulphated polysaccharides and polyphenolics, flavonoids, coumarins (glycoc...

journal_title：Planta medica

authors： Vlietinck AJ,De Bruyne T,Apers S,Pieters LA

更新日期：1998-03-01 00:00:00