Thyme extract, but not thymol, inhibits endothelin-induced contractions of isolated rat trachea.

abstract：:The structure of albifloranine 1, a new alkaloid of ibogane type from the stem bark of Tabernaemontana albiflora (M IQ.) Pull. (Apocynaceae) has been determined. A detailed (1)H NMR study of albifloranine 1, coronaridine 2 and heyneanine 3 is presented. ...

journal_title：Planta medica

authors： Kan C,Husson HP,Kan SK,Lounasmaa M

更新日期：1981-01-01 00:00:00

abstract：:Volatile constituents of the essential oils from leaves and inflorescences of Solidago chilensis Meyen were analyzed by GC-FID, GC-MS and 13C-NMR and thirty-six different compounds were identified. Pumiloxide, an unusual labdane diterpene, was found to be one of the major components in both oils (15.3 % and 12.3 %, re...

journal_title：Planta medica

authors： Vila R,Mundina M,Tomi F,Furlán R,Zacchino S,Casanova J,Cañigueral S

更新日期：2002-02-01 00:00:00

abstract：:(1)H- and (13)C-NMR spectral data are presented for six p-terphenylquinone derivatives (and for two monosubstituted quinones 1 and 2, used as model compounds) and for 9,10-phenanthraquinone and retenequinone. The chemical shifts were confirmed through correlation spectroscopy and NOE measurements. ...

journal_title：Planta medica

authors： Jokela R,Lounasmaa M

更新日期：1997-08-01 00:00:00

abstract：:Some diterpenoids show various biological activities, including anti-inflammatory, anti-HIV and anti-tumor activity. Previously, we have focused our research on the apoptosis-inducing properties of diterpenoids and found that some ent-kaurene-type diterpenoids induced apoptosis in human leukemia HL-60 cells. In this s...

journal_title：Planta medica

authors： Kondoh M,Nagashima F,Suzuki I,Harada M,Fujii M,Asakawa Y,Watanabe Y

更新日期：2005-11-01 00:00:00

abstract：:Three new xanthones, 22,23-dihydroxydihydrogambogenic acid (1), 12-hydroxygambogefic acid A (2), and hanburixanthone (3), along with thirteen known compounds were isolated from the resin of Garcinia hanburyi. The structures of the new compounds were determined by detailed analysis of 1D and 2D NMR spectra and by compa...

journal_title：Planta medica

authors： Deng YX,Guo T,Shao ZY,Xie H,Pan SL

更新日期：2013-06-01 00:00:00

abstract：:Bioassay directed fractionation of the (1:1) chloroform-methanol extract of Gentiana spathacea H.B.K (Gentianaceae) led to the isolation of gentiopicroside (gentiopricrin) (1), the major spasmolytic component of the plant. Gentiopicroside inhibited, in a concentration-dependent manner, the spontaneous contractions of ...

journal_title：Planta medica

authors： Rojas A,Bah M,Rojas JI,Gutiérrez DM

更新日期：2000-12-01 00:00:00

abstract：:A microdilution technique was developed for the assessment of in vitro cytotoxicity against KB cells derived from a human epidermoid carcinoma of the nasopharynx. The test was used to determine the cytotoxicity of a series of quassinoids, isolated from Brucea javanica, and which have previously been shown to demonstra...

journal_title：Planta medica

authors： Anderson MM,O'Neill MJ,Phillipson JD,Warhurst DC

更新日期：1991-02-01 00:00:00

abstract：:We have identified kamebakaurin as an inhibitor of NF-KB and elucidated its molecular mechanism as a specific inhibitor in the DNA-binding activity of the p50 subunit of NF-KB. Here, we describe its anti-inflammatory activity in in vitro and in vivo models. Kamebakaurin dose-dependently inhibited not only the expressi...

journal_title：Planta medica

authors： Lee JH,Choi JK,Noh MS,Hwang BY,Hong YS,Lee JJ

更新日期：2004-06-01 00:00:00

abstract：:From leaves of Penstemon barbatus Nutt. a new iridoid glucoside has been isolated. The structure was established mainly by spectroscopic methods ( (1)H-NMR, (13)C-NMR, IR, MS). ...

journal_title：Planta medica

authors： Junior P

更新日期：1982-06-01 00:00:00

abstract：:The antihyperglycemic action of andrographolide, an active principle in the leaves of Andrographis paniculata (Burm. f.) Nees, was investigated in streptozotocin-induced diabetic rats (STZ-diabetic rats). Oral treatment of andrographolide decreased the plasma glucose concentrations of STZ-diabetic rats in a dose-depen...

journal_title：Planta medica

authors： Yu BC,Hung CR,Chen WC,Cheng JT

更新日期：2003-12-01 00:00:00

abstract：:The analysis of the volatile compounds in the essential oil of SOLIDAGO CANADENSISL. sensu lato (Compositae) GC and GC-MS demonstrated the presence of at least 36 compounds, 18 of which were identified. The Major comonenets are gamma (2)- and delta-cadinenes. ...

journal_title：Planta medica

authors： Kalemba D,Góra J,Kurowska A

更新日期：1990-04-01 00:00:00

abstract：:Based on rDNA ITS sequences of D. officinale and the other 37 species of Dendrobium, a pair of allele-specific diagnostic primers, TP-JB01S and TP-JB01X, were designed to authenticate D. officinale from the other species. Before the diagnostic PCR, the primer pair, P1 and P2, for amplifying the whole ITS region was us...

journal_title：Planta medica

authors： Ding X,Wang Z,Zhou K,Xu L,Xu H,Wang Y

更新日期：2003-06-01 00:00:00

abstract：:VERATRUM CALIFORNICUM (Liliaceae) is an important monocotyledonous medicinal plant which is the only source of the anticancer compound cyclopamine. An IN VITRO culture system for somatic embryogenesis and green plant regeneration of VERATRUM CALIFORNICUM was developed. Embryogenic calli were induced from mature embryo...

journal_title：Planta medica

authors： Ma R,Ritala A,Oksman-Caldentey KM,Rischer H

更新日期：2006-10-01 00:00:00

abstract：:The known alkaloids (+/-)-stylopine, (+/-)-sinactine, protopine, (+)-bulbocapnine, (-)-domesticine, (+)-corydine and (+)-isoboldine were found in the mixture of alkaloids from Corydalis marschalliana (Papaveraceae), growing in Bulgaria. The alkaloids dehydronantenine, (+)-nantenine and oxonantenine were isolated for t...

journal_title：Planta medica

authors： Kiryakov HG,Iskrenova E,Kuzmanov B,Evstatieva L

更新日期：1981-03-01 00:00:00

abstract：:Increasingly, as a result of recent biochemical work, there exists a realistic possibility of taking a molecular genetic approach to the manipulation of alkaloid-producing pathways in plant tissue cultures. In the pathways forming indole alkaloids in CATHARANTHUS ROSEUS, tropane alkaloids in DATURA and HYOSCYAMUS spec...

journal_title：Planta medica

authors： Robins RJ,Waltons NJ,Hamill JD,Parr AJ,Rhodes MJ

更新日期：1991-10-01 00:00:00

abstract：:A micellar electrokinetic capillary chromatography (MEKC) method for the determination of xanthyletin and xanthoxyletin in the roots bark of three Citrus plants was developed for the first time. The electrophoresis buffer was 10 mmol/L sodium borate containing 50 mmol/L sodium dodecyl sulfate, 20% (v/v) acetonitrile a...

journal_title：Planta medica

authors： Wang SF,Ju Y,Chen XG,Hu ZD

更新日期：2003-05-01 00:00:00

abstract：:Use of herbal dietary supplements by the public is common and has been happening for centuries. In the United States, the Food and Drug Administration has a limited scope of regulation over marketed herbal dietary supplements, which may contain toxic botanical compounds that pose a public health risk. While the Food a...

journal_title：Planta medica

authors： Hudson A,Lopez E,Almalki AJ,Roe AL,Calderón AI

更新日期：2018-07-01 00:00:00

abstract：:The present study investigated the role of adenosine in the stimulatory action of paeoniflorin on in vitro glucose transport. Paeoniflorin increased the uptake of a radiolabeled, non-metabolizable glucose derivative into isolated white adipocytes of Wistar rat in a concentration-dependent manner and this action was ab...

journal_title：Planta medica

authors： Tang LM,Liu IM,Cheng JT

更新日期：2003-04-01 00:00:00

abstract：:Activator protein 1 (AP-1) is a transcription factor which plays a critical role in inflammation and carcinogenesis. The present study was conducted to investigate the effect of berberine, an isoquinoline alkaloid present in plants of the genera Berberis and Coptis, on the activity of AP-1 using a reporter gene assay ...

journal_title：Planta medica

authors： Fukuda K,Hibiya Y,Mutoh M,Koshiji M,Akao S,Fujiwara H

更新日期：1999-05-01 00:00:00

abstract：:Ginsenoside Ro, an oleanane-type saponin has been screened for activity in experimental models of acute and chronic hepatitis. Ginsenoside Ro (50 and 200 mg/kg, P.O.) inhibited the increase of serum glutamic oxaloacetic transaminase (s-GOT) and serum glutamic pyruvic transaminase (s-GPT) levels in D-galactosamine (Gal...

journal_title：Planta medica

authors： Matsuda H,Samukawa K,Kubo M

更新日期：1991-12-01 00:00:00

abstract：:Fractionation of the aqueous extract of Derris scandens stems extract using tests for eicosanoid inhibition resulted in the isolation of three isoflavonoids, genistein, its 7- O-alpha-rhamno(1-->6)-beta-glucosyl glycoside, a new compound, and two known isoprenyl derivatives 3'-gamma,gamma-dimethylallylweighteone and s...

journal_title：Planta medica

authors： Laupattarakasem P,Houghton PJ,Hoult JR

更新日期：2004-06-01 00:00:00

abstract：:A new cytotoxic cyclopenta[b]benzofuran derivative, aglaiformosanin (1) and three known cyclopenta[b]benzofuran derivatives (2 - 4) were isolated from the stem bark of Aglaia formosana. Compounds 1 - 4 exhibited potent cytotoxicity against the P-388, KB, HT-29, HL-60, and A549 cell lines. The structure of compound 1 w...

journal_title：Planta medica

authors： Wang SK,Duh CY

更新日期：2001-08-01 00:00:00

abstract：:Three flavonoids: norwogonin, dihydronorwogonin and baicalein, were isolated from the roots of Scutellaria baicalensis, as potential inhibitors of VHR dual-specificity protein tyrosine phosphatase (DS-PTPase). Norwogonin (IC 50 = 1.1 microM), dihydronorwogonin (IC 50 = 2.9 microM) and baicalein (IC 50 = 2.4 microM) sh...

journal_title：Planta medica

authors： Lee MS,Oh WK,Kim BY,Ahn SC,Kang DO,Sohn CB,Osada H,Ahn JS

更新日期：2002-12-01 00:00:00

abstract：:In order to evaluate the potency of novel antiviral drugs, 11 natural sulfated polysaccharides (SPs) from 10 green algae ( Enteromorpha compressa, Monostroma nitidum, Caulerpa brachypus, C. okamurai, C. scapelliformis, Chaetomorpha crassa, C. spiralis, Codium adhaerens, C. fragille, and C. latum) and 4 synthetic sulfa...

journal_title：Planta medica

authors： Lee JB,Hayashi K,Maeda M,Hayashi T

更新日期：2004-09-01 00:00:00

abstract：:The essential oil obtained from the aerial parts of Phlomis lanata has been analyzed by GC/MS. 48 compounds representing 96.85% of the oil were identified; alpha-pinene, limonene and trans-caryophyllene were found as its main components. The essential all showed a moderate in vitro activity against six Gram (+/-) bact...

journal_title：Planta medica

authors： Couladis M,Tanimanidis A,Tzakou O,Chinou IB,Harvala C

更新日期：2000-10-01 00:00:00

abstract：:The evidence for loss of Ca2+ homeostasis due to neuronal degeneration is considerable and rapidly increasing. In this study, we try to evaluate the protective effect of tetrandrine (TET), an alkaloid isolated from the Chinese medicinal herb Radix Stephania tetrandrae S., on amyloid-beta protein (Abeta) and 1-methyl-4...

journal_title：Planta medica

authors： Chiou WF,Lee WS,Yeh PH

更新日期：2006-11-01 00:00:00

abstract：:Oxygen radical injury and lipid peroxidation have been suggested as major causes of atherosclerosis, cancer, liver disease, and the aging process. More specifically, oxidative modification of low density lipoprotein (LDL) has been recognized as an important process of atherosclerosis. In this study, we determined the ...

journal_title：Planta medica

authors： Ide N,Nelson AB,Lau BH

更新日期：1997-06-01 00:00:00

abstract：:Hyperuricemia is a clinical condition characterized by an elevated level of serum uric acid and is a key risk factor for the development of gout and metabolic disorders. The existing urate-lowering therapies are often impractical for certain patient populations, providing a rationale to explore new agents with improve...

journal_title：Planta medica

authors： Kim JK,Kim WJ,Hyun JM,Lee JS,Kwon JG,Seo C,Song MJ,Choi CW,Hong SS,Park K,Kim P,Sung H,Lee JK,Choi Y

更新日期：2017-11-01 00:00:00

abstract：:Danggui buxue tang, an ancient formula composed of astragali radix and Angelicae sinensis radix, has been used for treating menopausal irregularity in women for more than 800 years in China. In danggui buxue tang, the complete functions of astragali radix require the assistance of Angelicae sinensis radix, and both he...

journal_title：Planta medica

authors： Zheng KY,Zhang ZX,Du CY,Zhang WL,Bi CW,Choi RC,Dong TT,Tsim KW

更新日期：2014-02-01 00:00:00

abstract：:Khat (Catha edulis Forsk.) is a perennial shrub whose young leaves are chewed for their psychostimulating and anorectic properties. The main active principles of khat are believed to be the phenylpropylamino alkaloids, primarily (-)-cathinone [(S)-α-aminopropiophenone], (+)-cathine [(1S)(2S)-norpseudoephedrine], and (...

journal_title：Planta medica

authors： Krizevski R,Bar E,Dudai N,Levy A,Lewinsohn E,Sitrit Y,Ben-Shabat S

更新日期：2012-05-01 00:00:00