Abstract:
:The hypoglycaemic effect of orally administered extracts of leaves and roots of Coccinia indica has been reported earlier. The oral administration of the pectin isolated from the fruit of the above plant at a dose of 200 mg/100 g BW/day showed a significant hypoglycaemic action in normal rats. Pectins isolated from many other plants have also been reported to have hypoglycaemic actions. The pectin administration resulted in a significant reduction in blood glucose and an increase in the liver glycogen. Glycogen synthetase activity was highly significant. Incorporation of labelled glucose into hepatic glycogen was also found to be higher. A significant reduction in phosphorylase activity was noted in the pectin-administered groups.
journal_name
Planta Medjournal_title
Planta medicaauthors
Kumar GP,Sudheesh S,Vijayalakshmi NRdoi
10.1055/s-2006-959693subject
Has Abstractpub_date
1993-08-01 00:00:00pages
330-2issue
4eissn
0032-0943issn
1439-0221journal_volume
59pub_type
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