[Immunologically active glycoproteins of Baptisia tinctoria].


:Chromatographically purified fractions of aqueous-ethanolic extracts from Baptisia tinctoria roots contained a strong lymphocyte DNA synthesis-stimulating activity. Electrophoretic analysis of these fractions revealed four distinct protein bands with molecular masses of P1 = 58 kD; P4 = 31 kD; P5 = 26 kD; and P6 = 14 kD. They contained carbohydrate as determined by periodic acid Schiff staining. An estimation of the approximate amount of sugar was done by using human transferrin as a reference, this method revealed the following values: P1 = 27%; P4 = 12%; P5 = 14%; and P6 = 8%. The mixture of proteins and every single band were immunoreactive with a polyclonal antiserum against Baptisia proteins determined in immune and dot blots, respectively. Electrophoretically purified proteins were characterized by tryptic cleavage and determination of their amino acid content. They contained several common amino acids, predominantly aspartic acid, glutamic acid, threonine, and alanine. The content of glucosamine and/or galactosamine was less than 0.2 Mol-per cent. The four proteins revealed pI values between 5.3 and 4.7. Protein P 4 was immunochemically related to phytohemagglutinin but, in contrast to PHA-P, it exhibited no hemagglutinating activity and no leucagglutinating activity like PHA-L.


Planta Med


Planta medica


Beuscher N,Scheit KH,Bodinet C,Kopanski L




Has Abstract


1989-08-01 00:00:00












  • Inhibition of HIV-1 reverse transcriptase and HIV-1 replication by Calophyllum coumarins and xanthones.

    abstract::As part of our continuing study on the Calophyllum species, a number of coumarins, xanthones and chromene acids from different Calophyllum species of Sri Lanka were tested for inhibitory activity against the HIV-1 and its virally-encoded reverse transcriptase (RT). These compounds were found to be inactive in both the...

    journal_title:Planta medica

    pub_type: 信件


    authors: Dharmaratne HR,Tan GT,Marasinghe GP,Pezzuto JM

    更新日期:2002-01-01 00:00:00

  • Biosynthesis of phenylalanine and tyrosine in claviceps.

    abstract::Some enzymes of the terminal steps of phenylalanine and tyrosine biosyntheses were investigated in various alkaloid-forming ergot strains. All strains studied utilize both arogenate and phenylpyruvate as an intermediate in L-phenylalanine synthesis. L-Tyrosine is preferentially or exclusively synthesized via the aroge...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Schmauder HP,Gröger D

    更新日期:1986-10-01 00:00:00

  • A New Biflavanone from the Bark of Garcinia kola1.

    abstract::The new I-3', II-3, 3', II-4', I-5, II-5, I-7, II-7-octahydroxy-I-4'-methoxy-I-3, II-8-biflavanone together with known biflavanones GB-1 and GB-2 were isolated from the bark of GARCINIA KOLA. ...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Kabangu K,Galeffi C,Aonzo E,Nicoletti M,Messana I

    更新日期:1987-06-01 00:00:00

  • Eremophilane sesquiterpene lactones from Ligularia virgaurea ssp. oligocephala.

    abstract::From an extract of the whole plant of Ligularia virgaurea ssp. oligocephala, three new eremophilane sesquiterpene lactones, 10alpha-hydroxy-1-oxoeremophila-7(11),8(9)-dien-12,8-olide (1), 6alpha,10alpha-dihydroxy-1-oxoeremophila-7(11),8(9)-dien-12,8-olide (2), 6beta,10beta-dihydroxyeremophila-7(11),8(9)-dien-12,8-olid...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Wu QX,Shi YP,Yang L

    更新日期:2004-05-01 00:00:00

  • Cytotoxic cyclopenta[b]benzofuran derivatives from the stem bark of Aglaia formosana.

    abstract::A new cytotoxic cyclopenta[b]benzofuran derivative, aglaiformosanin (1) and three known cyclopenta[b]benzofuran derivatives (2 - 4) were isolated from the stem bark of Aglaia formosana. Compounds 1 - 4 exhibited potent cytotoxicity against the P-388, KB, HT-29, HL-60, and A549 cell lines. The structure of compound 1 w...

    journal_title:Planta medica

    pub_type: 信件


    authors: Wang SK,Duh CY

    更新日期:2001-08-01 00:00:00

  • Pharmacokinetics of a Standardized Extract of Centella asiatica ECa 233 in Rats.

    abstract::ECa 233, a standardized extract of Centella asiatica, has been found to exhibit various positive neurological effects and to have a good safety profile. The present study aimed to explore the disposition kinetics of ECa 233, containing madecassoside (53.1 %) and asiaticoside (32.3 %), in rats. The extract was intraven...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Anukunwithaya T,Tantisira MH,Tantisira B,Khemawoot P

    更新日期:2017-05-01 00:00:00

  • Immunosuppressive lignans isolated from Saururus chinensis.

    abstract::Bioactivity-guided fractionation of Saururus chinensis (Saururaceae) using a lymphoproliferation assay led us to isolate 5 lignans (compounds 1 - 5). Compounds 1 - 5 were identified as sauchinone, (-)-saucerneol, saucerneol C, manassantin A, and manassantin B, respectively, by spectroscopic analyses. The immunosuppres...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Park SY,Lee SH,Choi WH,Koh EM,Seo JH,Ryu SY,Kim YS,Kwon DY,Koh WS

    更新日期:2007-06-01 00:00:00

  • A New Limonoid, Amoorinin, from the Stem Bark of Amoora rohituka.

    abstract::Evidence is presented for the structure of a new limonoid, amoorinin, from the stem bark of AMOORA ROHITUKA on the basis of spectral and chemical evidences. ...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Agnihotri VK,Srivastava SD,Srivastava SK

    更新日期:1987-06-01 00:00:00

  • Inhibition of activator protein 1 activity by berberine in human hepatoma cells.

    abstract::Activator protein 1 (AP-1) is a transcription factor which plays a critical role in inflammation and carcinogenesis. The present study was conducted to investigate the effect of berberine, an isoquinoline alkaloid present in plants of the genera Berberis and Coptis, on the activity of AP-1 using a reporter gene assay ...

    journal_title:Planta medica

    pub_type: 信件


    authors: Fukuda K,Hibiya Y,Mutoh M,Koshiji M,Akao S,Fujiwara H

    更新日期:1999-05-01 00:00:00

  • Thyme extract, but not thymol, inhibits endothelin-induced contractions of isolated rat trachea.

    abstract::Thyme extract is known to posses spasmolytic effects on isolated trachea and to increase ciliary activity. A small part of this effect is mediated via beta (2) receptors, but other receptors are supposed to be involved. Endothelin has a pathophysiological impact in asthma with respect to hyper-reagibility and contract...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Engelbertz J,Schwenk T,Kinzinger U,Schierstedt D,Verspohl EJ

    更新日期:2008-10-01 00:00:00

  • 11-deoxyalisol C and alisol D: new protostane-type triterpenoids from Alisma plantago-aquatica.

    abstract::New protostane-type triterpenes, 11-deoxyalisol C and alisol D, have been isolated from the rhizomes of ALISMA PLANTAGO-AQUATICA, and their structures have been elucidated on the basis of spectral and chemical data. ...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Fukuyama Y,Pei-Wu G,Rei W,Yamada T,Nakagawa K

    更新日期:1988-10-01 00:00:00

  • [A comparative study of the effects of selection and environmental factors on alkaloid accumulation in strains of Choisya ternata].

    abstract::The accumulation of two dihydrofuroquinoline alkaloids has been studied in seventeen strains of Choisya ternata (Rutaceae) initiated from the same tree. The contents of platydesminium and balfourodinium vary in heavy proportions. The effect of some factors (age of the culture, NAA or glucose concentrations of the medi...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Gras M,Crèche J,Chénieux JC,Rideau M

    更新日期:1982-12-01 00:00:00

  • Tetrandrine selectively protects against amyloid-beta protein - but not against MPTP-induced cytotoxicity in SK-N-SH neuroblastoma cells.

    abstract::The evidence for loss of Ca2+ homeostasis due to neuronal degeneration is considerable and rapidly increasing. In this study, we try to evaluate the protective effect of tetrandrine (TET), an alkaloid isolated from the Chinese medicinal herb Radix Stephania tetrandrae S., on amyloid-beta protein (Abeta) and 1-methyl-4...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Chiou WF,Lee WS,Yeh PH

    更新日期:2006-11-01 00:00:00

  • Mechanism of inhibition of peroxynitrite-induced oxidation and nitration by [6]-gingerol.

    abstract::[6]-Gingerol potently inhibits peroxynitrite-induced oxidation and nitration reactions, but its mechanism of action is unclear. In order to discover the mechanism of inhibition, [6]-gingerol was reacted with peroxynitrite and the reaction mixture was analyzed using HPLC. The HPLC chromatogram showed one novel peak, in...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Ippoushi K,Ito H,Horie H,Azuma K

    更新日期:2005-06-01 00:00:00

  • Antimicrobial hasubanalactam alkaloid from Stephania glabra.

    abstract::A novel hasubanalactam alkaloid, named glabradine, has been isolated from the tubers of Stephania glabra, together with three known quaternary protoberberine alkaloids, palmatine, dehydrocorydalmine and stepharanine. The structure of glabradine was assigned as 7-O-demethyl-N,O-dimethyloxostephinine, by means of rigoro...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Semwal DK,Rawat U

    更新日期:2009-03-01 00:00:00

  • Minor secondary metabolic products from the stem bark of Plumeria rubra Linn. displaying antimicrobial activities.

    abstract::Four new iridoids viz., plumeridoids A, B, and C and epiplumeridoid C were isolated from the stem bark of Plumeria rubra Linn. together with twenty-four known compounds viz., 1-( P-hydroxyphenyl)propan-1-one, isoplumericin, plumericin, dihydroplumericin, allamcin, fulvoplumerin, allamandin, plumieride, P- E-coumaric a...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Kuigoua GM,Kouam SF,Ngadjui BT,Schulz B,Green IR,Choudhary MI,Krohn K

    更新日期:2010-04-01 00:00:00

  • Acetylenes from Atractylis koreana.

    abstract::A reinvestigation of the rhizomes of ATRACTYLIS KOREANA afforded in addition to 1,3-diacetoxytetradeca-6,12-diene-8,10-diyne reported previously (1) two new C (14)-polyacetylenes with an ene-diyn-ene-chromophor and one new C (14)-polyacetylene beside two known compounds with an ene-diyne-diene-chromophor. Their struct...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Pachaly P,Lansing A,Neugebauer M,Sin KS

    更新日期:1990-10-01 00:00:00

  • Marine natural products research: current directions and future potential.

    abstract::Natural products research is increasingly turning to marine animals, plants, and microbes as source organisms. Several marine natural products are currently in preclinical and clinical evaluation, others show promising biological activities in in vitro and in vivo assays. Investigations of biological and chemical ecol...

    journal_title:Planta medica

    pub_type: 杂志文章,评审


    authors: König GM,Wright AD

    更新日期:1996-06-01 00:00:00

  • Recent development of antitumor agents from Chinese herbal medicines. Part II. High molecular compounds(3).

    abstract::High molecular compounds from Chinese herbal medicines, including ribosome-inactivating proteins and polysaccharides from both fungi and high plants have been tested for the treatment of malignant diseases. Polysaccharides possessing immunostimulating activities can be used as adjuvants in tumor treatment. The fungi c...

    journal_title:Planta medica

    pub_type: 杂志文章,评审


    authors: Tang W,Hemm I,Bertram B

    更新日期:2003-03-01 00:00:00

  • Polyacetylenic compounds and butanol fraction from Bidens pilosa can modulate the differentiation of helper T cells and prevent autoimmune diabetes in non-obese diabetic mice.

    abstract::Compelling evidence suggests that infiltrating CD4+ type I helper T (Th1) cells in the pancreatic islets play a pivotal role in the progression of diabetes in non-obese diabetic (NOD) mice. We demonstrate in the present report that a butanol fraction of B. pilosa suppressed the development of diabetes, helped maintain...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Chang SL,Chang CL,Chiang YM,Hsieh RH,Tzeng CR,Wu TK,Sytwu HK,Shyur LF,Yang WC

    更新日期:2004-11-01 00:00:00

  • New coumarins from Pterocaulon polystachyum.

    abstract::Aerial parts of Pterocaulon polystachyum from Chaco province, Argentina, afforded the known coumarins ayapin, isoscopoletin, prenyletin, prenyletin methyl ether, virgatenol, obtusinin, 5-methoxy-6,7-methylenedioxycoumarin, 5-(3,3-dimethylallyloxy)-6,7-methylenedioxycoumarin, 5-(2',3'-dihydroxy-3-methylbutanoxy)-6,7-me...

    journal_title:Planta medica

    pub_type: 信件


    authors: Vera N,Bardón A,Catalán CA,Gedris TE,Herz W

    更新日期:2001-10-01 00:00:00

  • Bioactivity-guided isolation of cytotoxic sesquiterpenes and flavonoids from Anthemis ruthenica.

    abstract::A new eudesmanolide sesquiterpene, sivasinolide 6-O-angelate (1), was isolated from the aerial parts of Anthemis ruthenica together with the known compounds chrysanin (2), tanacin (3), 3 beta-hydroxycostunolide (4), centauridin (5), and centaureidin (6). The compounds were obtained by means of bioactivity-guided fract...

    journal_title:Planta medica

    pub_type: 信件


    authors: Hajdú Z,Zupkó I,Réthy B,Forgo P,Hohmann J

    更新日期:2010-01-01 00:00:00

  • Characterization of Casearin X Metabolism by Rat and Human Liver Microsomes.

    abstract::Casearin X (CAS X) is the major clerodane diterpene isolated from the leaves of Casearia sylvestris and has been extensively studied due to its powerful cytotoxic activity at low concentrations. Promising results for in vivo antitumor action have also been described when CAS X was administered intraperitoneally in mic...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Moreira da Silva R,de Gaitani CM,Marques LMM,Fraige Baraco K,Cavalheiro AJ,de Moraes LAB,Lopes NP,de Oliveira ARM

    更新日期:2019-03-01 00:00:00

  • Bioactive coumarin derivatives from the fern Cyclosorus interruptus.

    abstract::Three new coumarin derivatives, compounds 1-3, three new furanocoumarins, compounds 4-6, and a novel dioxocane derivative, compound 7, were isolated from the fern Cyclosorus interruptus (Willd.) H. Itô. Based on spectrometric and spectroscopic analysis (FAB or El mass spectrometry as well as 1D and 2D NMR experiments)...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Quadri-Spinelli T,Heilmann J,Rali T,Sticher O

    更新日期:2000-12-01 00:00:00

  • Volatile Components of Cleistopholis patens.

    abstract::Volatile oils of the leaves, fruits and stem-bark of CLEISTOPHOLIS PATENTS Engl. et Diels. (Annonacae) were analysed by means of gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS). A total of sixty-one components were identified; qualitative and quantitative differences in the oil composition wer...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Ekundayo O,Laakso I,Oguntimein B,Hiltunen R

    更新日期:1988-08-01 00:00:00

  • GABA(A) receptor modulators from the Chinese herbal drug Junci Medulla--the pith of Juncus effusus.

    abstract::The gamma-amino butyric acid (GABA) type A (GABA(A)) receptor represents a crucial target for clinical agents in the treatment of anxiety and insomnia. Using the two-microelectrode voltage clamp technique on recombinant α₁β₂γ(2S) GABA (A) receptors, effusol (1) and dehydroeffusol (2) were isolated in a bioactivity-gui...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Singhuber J,Baburin I,Khom S,Zehl M,Urban E,Hering S,Kopp B

    更新日期:2012-03-01 00:00:00

  • Phytochemical Study of Eryngium triquetrum: Isolation of Polyacetylenes and Lignans.

    abstract::Phytochemical investigation of the ethyl acetate extract from the aerial parts of Eryngium triquetrum Vahl resulted in the isolation of new polyacetylenes, triquetridiol (6) and trans-epoxy-triquetrol (7a/7b, diastereomeric mixture), and the lignan demethoxy carolignan Z (8a/8b, erythro/threo pair), together with a se...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Bouzergoune F,Ciavatta ML,Bitam F,Carbone M,Aberkane MC,Gavagnin M

    更新日期:2016-11-01 00:00:00

  • Prediction of Permeation and Cellular Transport of Silybum marianum Extract Formulated in a Nanoemulsion by Using PAMPA and Caco-2 Cell Models.

    abstract::The present study explores the potential of nanoemulsion, a lipid drug delivery system, to improve solubility and oral absorption of Silybum marianum extract. The optimized formulation contained 40 mg/mL of commercial extract (4 % w/w) and it was composed of 2.5 g labrasol (20 %) as the oil phase, 1.5 g cremophor EL a...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Piazzini V,Rosseti C,Bigagli E,Luceri C,Bilia AR,Bergonzi MC

    更新日期:2017-10-01 00:00:00

  • Goji (Lycium barbarum and L. chinense): Phytochemistry, pharmacology and safety in the perspective of traditional uses and recent popularity.

    abstract::Since the beginning of this century, Goji berries and juice are being sold as health food products in western countries and praised in advertisements and in the media for well-being and as an anti-aging remedy. The popularity of Goji products has rapidly grown over the last years thanks to efficient marketing strategi...

    journal_title:Planta medica

    pub_type: 杂志文章,评审


    authors: Potterat O

    更新日期:2010-01-01 00:00:00

  • Chemical properties and anti-complementary activities of polysaccharide fractions from roots and leaves of Panax ginseng.

    abstract::Water-soluble and alkaline-soluble polysaccharide fractions, prepared from roots and leaves of PANAX GINSENG C.A. Meyer, were fractionated into strongly acidic, weakly acidic, and neutral polysaccharide fractions by cetyltrimethyammonium bromide, respectively. The roots contained a larger amount of crude polysaccharid...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Gao QP,Kiyohara H,Cyong JC,Yamada H

    更新日期:1989-02-01 00:00:00