abstract：:Alzheimer's disease (AD) is on the rise all over the world, and brings with it great challenges to medical care and heavy burdens to family and society. Accurate diagnosis and differential diagnosis are of great importance. Tau positron emission tomography (PET) might offer novel insights and be of great assistance in...

journal_title：Annals of nuclear medicine

authors： Zhang W,Xu S,Yu H,Li X,Jin Z,Li Y,He Z

更新日期：2021-01-18 00:00:00

abstract：PURPOSE:Our purpose was to explore the clinical significance of unexpected osseous foci on 18F-FDG-PET without correlative CT abnormalities (FWCT) in patients referred for oncologic evaluation. The significance of FDG-avid foci without correlative CT abnormalities has been previously explored in tissues such as breast,...

journal_title：Annals of nuclear medicine

authors： Zamora E,Valdivia AY

更新日期：2021-01-13 00:00:00

abstract：OBJECTIVE:The variability of physiologic 18F-FDG uptake in the myocardium has hampered the accurate evaluation of cardiac glucose metabolism. We investigated the effects of multiple factors, including fasting duration and physical activity, on the physiologic uptake of 18F-FDG by the myocardium in healthy participants....

journal_title：Annals of nuclear medicine

authors： Kang JY,Lee MY,Kim YH

更新日期：2021-01-02 00:00:00

abstract：OBJECTIVE:The performance characteristics of the SPECT sub-system S102 of the ALBIRA II PET/SPECT/CT are analyzed for the 80 mm field of view (FOV) to evaluate the potential in-vivo imaging in rats, based on measurements of the system response for the commonly used Technetium-99 m (99mTc) in small animal imaging. METH...

journal_title：Annals of nuclear medicine

authors： Attarwala AA,Hardiansyah D,Romanó C,Jiménez-Franco LD,Roscher M,Wängler B,Glatting G

更新日期：2021-01-01 00:00:00

abstract：PURPOSE:To evaluate the prognostic role of end-of-treatment (EoT) FDG-PET/CT parameters in diffuse large B cell lymphoma (DLBCL), and then to explore a pilot application of Neural Networks (NN) in predicting time-to-relapse. METHODS:For conventional survival analysis, parameters as Deauville score (DS) and quantitativ...

journal_title：Annals of nuclear medicine

authors： Annunziata S,Pelliccioni A,Hohaus S,Maiolo E,Cuccaro A,Giordano A

更新日期：2021-01-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to elucidate the causes of false-negative cases of technetium-99 m methoxyisobutylisonitrile scintigraphy (MIBI) for hyperparathyroidism. METHODS:Consecutive MIBI examinations performed in 154 patients between April 2011 and March 2017 were retrospectively reviewed. Sensitivities of...

journal_title：Annals of nuclear medicine

authors： Ishii S,Sugawara S,Yaginuma Y,Kobiyama H,Hiruta M,Watanabe H,Yamakuni R,Hakozaki M,Fujimaki H,Ito H

更新日期：2020-12-01 00:00:00

abstract：:Prostate-specific membrane antigen (PSMA) is a transmembrane glycoprotein highly expressed by prostate cancer cells. PSMA-based radioligand therapy (RLT) emerged as a promising therapeutic option for prostate cancer in the early 2000s, and has been clinically validated with great enthusiasm during these past two decad...

journal_title：Annals of nuclear medicine

authors： Inubushi M,Miura H,Kuji I,Ito K,Minamimoto R

更新日期：2020-12-01 00:00:00

abstract：OBJECTIVE:The main aim of this work is to build a robust Convolutional Neural Network (CNN) algorithm that efficiently and quickly classifies bone scintigraphy images, by determining the presence or absence of prostate cancer metastasis. METHODS:CNN, widely applied in medical image classification, was used for bone sc...

journal_title：Annals of nuclear medicine

authors： Papandrianos N,Papageorgiou EI,Anagnostis A

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVE:In this retrospective, single-center observational study, we investigated whether discontinuing metformin for at least 48 h prevents metformin-induced [18F]fluorodeoxyglucose (FDG) uptake in all segments of the colon. METHODS:Patients with type 2 diabetes who were using metformin before undergoing an FDG PET...

journal_title：Annals of nuclear medicine

authors： Schreuder N,Klarenbeek H,Vendel BN,Jager PL,Kosterink JGW,van Puijenbroek EP

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVE:To examine the patterns of longitudinal tau accumulation and cortical atrophy and their association in subjects with mild cognitive impairment (MCI). METHODS:We collected 23 participants (60-89 years old, 11 males/12 females) with MCI from the Alzheimer's Disease Neuroimaging Initiative database. All partici...

journal_title：Annals of nuclear medicine

authors： Xu G,Zheng S,Zhu Z,Yu X,Jiang J,Jiang J,Chu Z,Alzheimer’s Disease Neuroimaging Initiative.

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVE:Radium-223 (223Ra) has been approved for treatment in patients with metastatic castration-resistant prostatic cancer (mCRPC) and bone metastasis. This α-emitting radionuclide has a beneficial effect on pain and is also capable to increase overall survival (OS). Several studies evaluated the prognostic value o...

journal_title：Annals of nuclear medicine

authors： Frantellizzi V,Monari F,Mascia M,Costa R,Rubini G,Spanu A,Di Rocco A,Lodi Rizzini E,Cindolo L,Licari M,Lavelli V,Nuvoli S,De Angelis C,Dionisi V,Ferrari C,De Vincentis G

更新日期：2020-10-01 00:00:00

abstract：OBJECTIVE:This study aimed to determine changes in FDG-PET/CT after pleurodesis with OK-432 and to investigate differences in the changes between non-malignant and malignant lesions. METHODS:Study participants were 17 patients with a history of malignant chest disease who underwent FDG-PET/CT after pleurodesis using O...

journal_title：Annals of nuclear medicine

authors： Nishimori M,Yoshimatsu R,Iwasa H,Miyatake K,Nitta N,Anayama T,Yamagami T

更新日期：2020-10-01 00:00:00

abstract：OBJECTIVE:A positron emission tomography (PET) scanner using a silicon photomultiplier (SiPM PET) in place of a photomultiplier tube significantly improves the spatial and time resolution. It may also improve the evaluation of smaller lesions compared to conventional (non-SiPM) PET scanners. We compared the maximum sta...

journal_title：Annals of nuclear medicine

authors： Kojima I,Takanami K,Ogawa T,Sakamoto M,Nagai H,Miyashita H,Iikubo M

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVES:Currently, neck ultrasound is the preferred preoperative imaging in patients with secondary/tertiary hyperparathyroidism, and the use of Tc-99m sestamibi scan is limited in these patients. We conducted this study to compare the diagnostic utilities of F-18 fluorocholine PET/CT, Tc-99m sestamibi scintigraphy,...

journal_title：Annals of nuclear medicine

authors： Chen YH,Chen HT,Lee MC,Liu SH,Wang LY,Lue KH,Chan SC

更新日期：2020-08-01 00:00:00

abstract：OBJECTIVE:We examined the diagnostic value of brain perfusion single-photon emission computed tomography (SPECT) using voxel-based statistical analysis with CT-based attenuation correction (CT-AC) by comparing it to that with Chang's AC in mild cognitive impairment (MCI) patients and attempted to locate brain areas tha...

journal_title：Annals of nuclear medicine

authors： Sohara K,Kiriyama T,Mizumura S,Ishiwata A,Yamazaki M,Kimura K,Kumita SI

更新日期：2020-07-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to investigate the outcomes and prognostic factors of high-dose 131I-metaiodobenzylguanidine (131I-MIBG) therapy in patients with refractory or relapsed neuroblastoma (NBL) in Japan. METHODS:We retrospectively analyzed 20 patients with refractory or relapsed high-risk NBL who underwe...

journal_title：Annals of nuclear medicine

authors： Kayano D,Wakabayashi H,Nakajima K,Kuroda R,Watanabe S,Inaki A,Toratani A,Akatani N,Yamase T,Kunita Y,Hiromasa T,Takata A,Mori H,Saito S,Araki R,Taki J,Kinuya S

更新日期：2020-06-01 00:00:00

abstract：:Most of the acute ischemic events, such as acute coronary syndromes and stroke, are attributed to vulnerable plaques. These lesions have common histological and pathophysiological features, including inflammatory cell infiltration, neo-angiogenesis, remodelling, haemorrhage predisposition, thin fibrous cap, large lipi...

journal_title：Annals of nuclear medicine

authors： Giannakou S,Angelidis G,Tsougos I,Valotassiou V,Kappas K,Georgoulias P

更新日期：2020-05-01 00:00:00

abstract：OBJECTIVE:To evaluate the value of Bayesian penalized likelihood (BPL) reconstruction for improving lesion conspicuity of malignant lung tumors on 18F-fluoro-2-deoxy-D-glucose (FDG) positron emission tomography computed tomography (PET/CT) as compared with the ordered subset expectation maximization (OSEM) reconstructi...

journal_title：Annals of nuclear medicine

authors： Kurita Y,Ichikawa Y,Nakanishi T,Tomita Y,Hasegawa D,Murashima S,Hirano T,Sakuma H

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:The aim of the study was to compare widely used ordered subset expectation maximisation (OSEM) algorithm with a new Bayesian penalised likelihood (BPL) Q.Clear algorithm in 18F-PSMA-1007 PET/CT. METHODS:We retrospectively assessed 25 18F-PSMA-1007 PET/CT scans with both OSEM and Q.Clear reconstructions avai...

journal_title：Annals of nuclear medicine

authors： Witkowska-Patena E,Budzyńska A,Giżewska A,Dziuk M,Walęcka-Mazur A

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:Despite recent technological advances allowing for quantitative single-photon emission computed tomography (SPECT), quantitative SPECT has not been widely used in the clinical practice of osteoporosis. The aim of this study is to evaluate the feasibility of quantitative bone SPECT/CT for measuring lumbar sta...

journal_title：Annals of nuclear medicine

authors： Huang K,Feng Y,Liu D,Liang W,Li L

更新日期：2020-02-01 00:00:00

abstract：OBJECTIVE:The tumor-to-normal tissue (T/N) boron ratio is determined in a patient prior to boron neutron capture therapy (BNCT) using 4-borono-2-18F-fluoro-L-phenylalanine (18F-FBPA) positron emission tomography (PET). The T/N ratio is used as a reference parameter to calculate BNCT dose and to evaluate treatment effec...

journal_title：Annals of nuclear medicine

authors： Lin YC,Chou FI,Yang BH,Chang CW,Chen YW,Hwang JJ

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVE:On hepatobiliary scintigraphy, "preferential gallbladder (GB) filling without tracer excretion into the small bowel (SB) [p-GB-no-SB]" is occasionally seen on images obtained up to an hour. In such cases, many practitioners administer cholecystokinin (CCK) (even when the measurement of GB ejection fraction is...

journal_title：Annals of nuclear medicine

authors： Choi HJ,Jacene H,Kim CK

更新日期：2019-10-01 00:00:00

abstract：OBJECTIVE:Vesicoureteral reflux (VUR) is a major risk factor for recurrent symptomatic urinary tract infection (UTI) in pediatric patients. In addition, dimercaptosuccinic acid renal scintigraphy (DMSA) is an important diagnostic modality of VUR. However, the value of DMSA for predicting recurrent pediatric UTI has not...

journal_title：Annals of nuclear medicine

authors： Kim D,Yoon HJ,Woo SH,Lee WJ,Kim BS,Chung YA,Oh JK

更新日期：2019-09-01 00:00:00

abstract：OBJECTIVES:Visceral leishmaniasis (VL) is the most severe manifestation of the infection caused by the protozoan Leishmania, recently on increase in Italy and Spain. The aim of the study was to describe FDG uptake patterns in VL patients (pts) who underwent 18F-FDG PET/CT. METHODS:A retrospective monocentric study of ...

journal_title：Annals of nuclear medicine

authors： Zanoni L,Varani S,Attard L,Morigi JJ,Vanino E,Ortalli M,Fonti C,Viale P,Re MC,Fanti S,Ambrosini V

更新日期：2019-09-01 00:00:00

abstract：OBJECTIVE:Chemobrain is a recently proposed pathological entity. 18F-FDG PET/CT can show objective abnormalities to explain brain disorders caused by chemotherapy, although no study has investigated these phenomena in children to date. The main objective of the present study was to examine quantitatively the effects of...

journal_title：Annals of nuclear medicine

authors： Tauty A,Noblet V,Paillard C,Fornecker LM,Namer IJ,Bund C

更新日期：2019-08-01 00:00:00

abstract：OBJECTIVE:Mantle cell lymphoma (MCL) is an aggressive lymphoma sub-type with poor prognosis and high 18F-FDG avidity at PET/CT; nowadays, no validated criteria for PET/CT in treatment response evaluation and prediction of outcome are present. The aim of study was to investigate whether the metabolic PET/CT features may...

journal_title：Annals of nuclear medicine

authors： Albano D,Bosio G,Bianchetti N,Pagani C,Re A,Tucci A,Giubbini R,Bertagna F

更新日期：2019-07-01 00:00:00

abstract：OBJECTIVE:Currently, the diagnosis of bone flap osteomyelitis (BFO) remains a challenge for medical imaging. The present study aimed to identify predictive scintigraphic patterns of BFO. METHODS:This retrospective study reviewed planar bone scan of patients with suspected BFO between 2010, and 2016. A total of 15 pati...

journal_title：Annals of nuclear medicine

authors： Bani Sadr A,Gregoire B,Tordo J,Guyotat J,Boibieux A,Janier M

更新日期：2019-06-01 00:00:00

abstract：OBJECTIVE:Pre-clinical studies with gallium-68 zoledronate ([68Ga]Ga-DOTAZOL) have proposed it to be a potent bisphosphonate for PET/CT diagnosis of bone diseases and diagnostic counterpart to [177Lu]Lu-DOTAZOL and [225Ac]Ac-DOTAZOL. This study aims to be the first human biodistribution and dosimetric analysis of [68Ga...

journal_title：Annals of nuclear medicine

authors： Khawar A,Eppard E,Roesch F,Ahmadzadehfar H,Kürpig S,Meisenheimer M,Gaertner FC,Essler M,Bundschuh RA

更新日期：2019-06-01 00:00:00

abstract：OBJECTIVE:To assess the role of serial FLT-PET scans during early neoadjuvant treatment as a prognostic marker of response to treatment and survival. METHODS:This study is a prospective cohort study which draws from a larger original study which examined the utility of FLT-PET imaging across multiple cancers. Our coho...

journal_title：Annals of nuclear medicine

authors： Ueberroth BE,Lawhorn-Crews JM,Heilbrun LK,Smith DW,Akoury J,Ali-Fehmi R,Eiseler NT,Shields AF

更新日期：2019-06-01 00:00:00

abstract：OBJECTIVE:To demonstrate the effect of clinicopathological factors on 68Ga-PSMA-11 PET/CT positivity at the time of biochemical recurrence (BCR) of localized prostate cancer (PCa) following definitive therapy. METHODS:We retrospectively reviewed our institutional database for PCa patients who had BCR and subsequently ...

journal_title：Annals of nuclear medicine

authors： Aydin AM,Haberal B,Artykov M,Bilen CY,Yazici S

更新日期：2019-05-01 00:00:00

abstract：OBJECTIVE:Bone-seeking radiopharmaceuticals have the main role in the treatment of painful bone metastases. The aim of this study was to dosimetrically compare radiopharmaceuticals in use for bone pain palliation therapy and bone scan. METHODS:The MCNPX code was used to simulate the radiation transport in a vertebral ...

journal_title：Annals of nuclear medicine

authors： Sadremomtaz A,Masoumi M

更新日期：2019-04-01 00:00:00

abstract：OBJECTIVE:Among different PET tracers, 18F-fludeoxyglucose (FDG) and 11C-choline are known to have a high tumor uptake correlated with a high mitotic index of tumor cells. Thus, the uptake of 18F-FDG and 11C-choline may be dependent on the cell cycle. In the present study, we examined the uptake of 18F-FDG and 11C-chol...

journal_title：Annals of nuclear medicine

authors： Roppongi M,Izumisawa M,Terasaki K,Muraki Y,Shozushima M

更新日期：2019-04-01 00:00:00

abstract：OBJECTIVE:Radio-guided sentinel node (SN) biopsy is a standard method used in the treatment of early breast cancer. Single photon emission computed tomography with computed tomography (SPECT/CT) has been commonly used for SN detection. SPECT/CT adds precise anatomical information of SN sites, and it is reported that mo...

journal_title：Annals of nuclear medicine

authors： Koizumi M,Koyama M

更新日期：2019-03-01 00:00:00

abstract：OBJECTIVE:The Response Evaluation Criteria In Solid Tumors (RECIST) is the most used radiological method for evaluating response after peptide receptor radionuclide therapy (PRRT) in patients with neuroendocrine tumors. This method may give too positive estimates of response in slow growing tumors as it allows a substa...

journal_title：Annals of nuclear medicine

authors： Løitegård T,Berntzen DT,Thiis-Evensen E

更新日期：2019-03-01 00:00:00

abstract：:Radium-223 dichloride (Ra-223) is the first targeted alpha therapy approved for the treatment of patients with castration-resistant prostate cancer (CRPC) with bone metastasis. Ra-223 improved overall survival in the international Phase III ALSYMPCA (ALpharadin in SYMPtomatic Prostate Cancer) study. Ra-223 was also de...

journal_title：Annals of nuclear medicine

authors： Hosono M,Ikebuchi H,Nakamura Y,Yanagida S,Kinuya S

更新日期：2019-03-01 00:00:00

abstract：OBJECTIVES:This study was designed to investigate the efficacy of 99mtechnetium-three polyethylene glycol spacers-arginine-glycine-aspartic acid ([99mTc]3PRGD2) in the evaluation of patients with esophageal cancer. METHODS:Twenty-nine patients with a suspected esophageal lesion and for whom definite pathological diagn...

journal_title：Annals of nuclear medicine

authors： Zheng S,Chen Z,Huang C,Chen Y,Miao W

更新日期：2019-02-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to investigate if increased serum thyroglobulin (Tg) levels after radioactive iodine (RAI) showed more therapeutic effects in patients with differentiated thyroid cancer (DTC). METHODS:Data of 65 patients with DTC who underwent RAI from June 2014 to September 2016 were reviewed. Ser...

journal_title：Annals of nuclear medicine

authors： Choi JH,Lim I,Lee I,Byun BH,Kim BI,Choi CW,Lim SM

更新日期：2019-02-01 00:00:00

abstract：OBJECTS:The purpose was to evaluate the correlation of the pre-treatment hematological parameters with metabolic parameters of primary tumor in baseline 18F-FDG PET/CT in patients with colorectal cancer (CRC) and estimate the prognostic value of both. METHODS:We retrospectively investigated 231 patients with CRC who u...

journal_title：Annals of nuclear medicine

authors： Xu J,Li Y,Hu S,Lu L,Gao Z,Yuan H

更新日期：2019-01-01 00:00:00

abstract：AIM:18F-Choline (FCH) uptake parameters are strong indicators of aggressive disease in prostate cancer. Functional parameters derived by magnetic resonance imaging (MRI) are also correlated to aggressive disease. The aim of this work was to evaluate the relationship between metabolic parameters derived by FCH PET/CT an...

journal_title：Annals of nuclear medicine

authors： Palard-Novello X,Beuzit L,Gambarota G,Le Jeune F,Garin E,Salaün PY,Devillers A,Querellou S,Bourguet P,Saint-Jalmes H

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVE:To investigate the utility of 13N-ammonia PET/CT imaging in the differential diagnosis of gliomas and brain inflammations. METHODS:13N-ammonia PET/CT imaging data of 77 patients with gliomas and 34 patients with brain inflammations were retrospectively analyzed. No patients received any treatment before 13N-...

journal_title：Annals of nuclear medicine

authors： Yi C,Shi X,Zhang X,Luo G,Zhang B,Zhang X

更新日期：2019-01-01 00:00:00