Development of Convolutional Neural Networks to identify bone metastasis for prostate cancer patients in bone scintigraphy.

abstract：OBJECTIVE:4-Benzyl-1-(3-iodobenzylsulfonyl)piperidine, 4-B-IBSP, has shown high-binding affinity to both sigma (σ) receptors in our previous work. In current study, radiolabeling and preclinical evaluation of 4-benzyl-1-(3-[125I]-iodobenzylsulfonyl)piperidine, 4-B-[125I]IBSP, in human ductal breast carcinoma (T47D) cel...

journal_title：Annals of nuclear medicine

authors： Sadeghzadeh M,Alirezapour B,Charkhlooie GA,Baghery MK,Khorouti A

更新日期：2017-05-01 00:00:00

abstract：OBJECTIVE:Variable uptake of 2-deoxy-2-[18F]fluoro-D-glucose (FDG) has been noticed in positron emission tomography (PET) studies of gastric carcinoma patients, with low uptake occurring especially in some particular histological subtypes and early carcinomas. But this phenomenon has not been adequately explained. The ...

journal_title：Annals of nuclear medicine

authors： Yamada A,Oguchi K,Fukushima M,Imai Y,Kadoya M

更新日期：2006-11-01 00:00:00

abstract：OBJECTIVE:An iterative reconstruction method in combination with resolution recovery, attenuation and scatter corrections (IR-RASC) can improve image quality. It, however, is undetermined whether this technique can improve the detection of coronary artery disease (CAD) when automated quantitative analysis is used. This...

journal_title：Annals of nuclear medicine

authors： Chono T,Onoguchi M,Shibutani T,Hashimoto A,Nakata T,Yama N,Tsuchihashi K,Hatakenaka M

更新日期：2017-02-01 00:00:00

abstract：:We report a functional neuroimaging study of a patient clinically diagnosed with Korsakoff syndrome. Positron emission tomography (PET) with the 15O inhalation method showed decreased regional cerebral blood flow (rCBF) and decreased regional cerebral metabolic ratio for oxygen (rCMRO2) in the bilateral fronto-tempora...

journal_title：Annals of nuclear medicine

authors： Matsuda K,Yamaji S,Ishii K,Sasaki M,Sakamoto S,Kitagaki H,Imamura T,Mori E

更新日期：1997-02-01 00:00:00

abstract：:A method has been described to optimize the cutoff frequency of the Butterworth filter for brain SPECT imaging. Since a computer simulation study has demonstrated that separation between an object signal and the random noise in projection images in a spatial-frequency domain is influenced by the total number of counts...

journal_title：Annals of nuclear medicine

authors： Minoshima S,Maruno H,Yui N,Togawa T,Kinoshita F,Kubota M,Berger KL,Uchida Y,Uno K,Arimizu N

更新日期：1993-05-01 00:00:00

abstract：OBJECTIVE:To determine an appropriate threshold value for delineation of the target in positron emission tomography (PET) and to investigate whether PET can delineate an internal target volume (ITV), a series of phantom studies were performed. METHODS:An ellipse phantom (background) was filled with 1028 Bq/ml of [(18)...

journal_title：Annals of nuclear medicine

authors： Okubo M,Nishimura Y,Nakamatsu K,Okumura M,Shibata T,Kanamori S,Hanaoka K,Hosono M

更新日期：2008-08-01 00:00:00

abstract：OBJECTIVE:Radium-223 (223Ra) has been approved for treatment in patients with metastatic castration-resistant prostatic cancer (mCRPC) and bone metastasis. This α-emitting radionuclide has a beneficial effect on pain and is also capable to increase overall survival (OS). Several studies evaluated the prognostic value o...

journal_title：Annals of nuclear medicine

authors： Frantellizzi V,Monari F,Mascia M,Costa R,Rubini G,Spanu A,Di Rocco A,Lodi Rizzini E,Cindolo L,Licari M,Lavelli V,Nuvoli S,De Angelis C,Dionisi V,Ferrari C,De Vincentis G

更新日期：2020-10-01 00:00:00

abstract：OBJECTIVE:Epidermal growth factor receptor tyrosine kinase (EGFR-TK) represents an attractive target for tumor diagnosis agents. Previously, the radioiodinated 4-(3-iodoanilino)-6,7-diethoxyquinazoline ([(125)I]m-IPQ) has been reported to possess good characteristics as a tumor imaging agent; however, it was also found...

journal_title：Annals of nuclear medicine

authors： Hirata M,Kanai Y,Naka S,Matsumuro K,Kagawa S,Yoshimoto M,Ohmomo Y

更新日期：2012-06-01 00:00:00

abstract：OBJECTIVE:To clarify the difference of (18)F-FDG uptake kinetics between FDG-avid metastatic lymph nodes (LNs) in patients with non-small-cell lung cancer (NSCLC) and FDG-avid benign LNs associated with various etiologies on dual-time point PET/CT scan, and to determine the optimal parameter for differentiation. METHO...

journal_title：Annals of nuclear medicine

authors： Suga K,Kawakami Y,Hiyama A,Sugi K,Okabe K,Matsumoto T,Ueda K,Tanaka N,Matsunaga N

更新日期：2009-08-01 00:00:00

abstract：PURPOSE:Our purpose was to explore the clinical significance of unexpected osseous foci on 18F-FDG-PET without correlative CT abnormalities (FWCT) in patients referred for oncologic evaluation. The significance of FDG-avid foci without correlative CT abnormalities has been previously explored in tissues such as breast,...

journal_title：Annals of nuclear medicine

authors： Zamora E,Valdivia AY

更新日期：2021-01-13 00:00:00

abstract：:Attenuation correction is very important for quantitative SPECT imaging. We designed an uncollimated non-uniform line array source (non-uniform LAS) for attenuation correction based on transmission computed tomography (TCT) using Tc-99m and compared its performance with an uncollimated uniform line array source (unifo...

journal_title：Annals of nuclear medicine

authors： Kojima A,Kawanaka K,Nakaura T,Shiraishi S,Utsunomiya D,Katsuda N,Tomiguchi S,Yamashita Y,Matsumoto M,Motomura N,Ichihara T

更新日期：2004-07-01 00:00:00

abstract：:Prostate-specific membrane antigen (PSMA) is a transmembrane glycoprotein highly expressed by prostate cancer cells. PSMA-based radioligand therapy (RLT) emerged as a promising therapeutic option for prostate cancer in the early 2000s, and has been clinically validated with great enthusiasm during these past two decad...

journal_title：Annals of nuclear medicine

authors： Inubushi M,Miura H,Kuji I,Ito K,Minamimoto R

更新日期：2020-12-01 00:00:00

abstract：:We report the first clinical PET study using [1-methyl-11C]8-dicyclopropylmethyl-1-methyl-3-propylxanthine ([11C]MPDX) for imaging adenosine A1 receptors in the human brain. The binding of [11C]MPDX evaluated quantitatively as the distribution volume by a graphical analysis was high in the striatum and thalamus, and l...

journal_title：Annals of nuclear medicine

authors： Fukumitsu N,Ishii K,Kimura Y,Oda K,Sasaki T,Mori Y,Ishiwata K

更新日期：2003-09-01 00:00:00

abstract：OBJECTIVE:To investigate the genotoxic effects of (90)Y and (186)Re in patients with hemophilia who were undergoing radionuclide synovectomy (RS) procedure in the last 3 years. METHODS:Nineteen patients were enrolled in the study. Most of the patients (n = 17) were hemophilia-A (mean age 20.6 ± 10.5 years) and 18 pati...

journal_title：Annals of nuclear medicine

authors： Kavakli K,Cogulu O,Karaca E,Durmaz B,Ozkinay F,Aydogdu S,Ozkilic H,Balkan C,Karapinar D,Ay Y

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:Radio-guided sentinel node (SN) biopsy is a standard method used in the treatment of early breast cancer. Single photon emission computed tomography with computed tomography (SPECT/CT) has been commonly used for SN detection. SPECT/CT adds precise anatomical information of SN sites, and it is reported that mo...

journal_title：Annals of nuclear medicine

authors： Koizumi M,Koyama M

更新日期：2019-03-01 00:00:00

abstract：:A 48-year-old woman with left adrenal tumor, which showed increased uptake of [18F] 2-fluoro-2-deoxy-D-glucose (FDG) was presented. Her adrenal tumor was incidentally discovered, although she had no remarkable illness, and her blood pressure was normal. Hormonal examination including dexamethason suppression test and ...

journal_title：Annals of nuclear medicine

authors： Shimizu A,Oriuchi N,Tsushima Y,Higuchi T,Aoki J,Endo K

更新日期：2003-07-01 00:00:00

abstract：UNLABELLED:To determine the utility of the myocardial tracer Tc-99m-tetrofosmin in the examination of patients with left bundle branch block (LBBB) and to investigate Tc-99m-tetrofosmin uptake and retention in the myocardium, early and delayed Tc-99m-tetrofosmin SPECT was performed in 10 patients having LBBB without co...

journal_title：Annals of nuclear medicine

authors： Sugihara H,Kinoshita N,Adachi Y,Taniguchi Y,Ohtsuki K,Azuma A,Adachi H,Ushijima Y,Nakagawa M,Maeda T

更新日期：1998-10-01 00:00:00

abstract：:Scintigraphy with 99mTc-diethylenetriamine pentaacetic acid galactosyl human serum albumin (99mTc-GSA) was performed on 102 patients, then the hepatic extraction fraction (HEF), the rate constant for liver uptake of the tracer from the blood (K1) and the hepatic blood flow index (HBFI) were determined by spectral anal...

journal_title：Annals of nuclear medicine

authors： Fukui A,Murase K,Tsuda T,Fujii T,Ikezoe J

更新日期：2000-12-01 00:00:00

abstract：:F-18 fluorodeoxyglucose positron emission tomography (FDG-PET) imaging is a useful modality in the detection of various tumors, including colon cancer and gastric cancer. We evaluated a patient with duodenal cancer with multiple metastases including brain metastases using FDG-PET imaging. It revealed multiple tumor up...

journal_title：Annals of nuclear medicine

authors： Watanabe N,Hayashi S,Kato H,Shimizu M,Kamisaki Y,Noguchi K,Kishida M,Matsunari I,Hisada K,Seto H

更新日期：2004-06-01 00:00:00

abstract：:To design a mathematical model for quantifying cerebral blood flow using 99mTc-hexamethyl-propyleneamine oxime (HM-PAO), basic studies were performed in animals and human volunteers. Microautoradiography revealed that HM-PAO crossed the blood-brain barrier. Thin layer chromatographic studies demonstrated the rapid dis...

journal_title：Annals of nuclear medicine

authors： Matsuda H,Oba H,Terada H,Tsuji S,Sumiya H,Shiba K,Seki H,Imai K,Mori H,Hisada K

更新日期：1988-05-01 00:00:00

abstract：:Cerebral perfusion single photon emission computed tomography (SPECT) has been used to confirm the localization of the epileptic focus and the evaluation of seizure. Recently, diffusion-weighted MR imaging (DWI) has been recognized for evaluation of seizure activity. We describe a case of transient seizure activity de...

journal_title：Annals of nuclear medicine

authors： Sagiuchi T,Ishii K,Asano Y,Aoki Y,Woodhams R,Yanaihara H,Kan S,Hayakawa K

更新日期：2001-06-01 00:00:00

abstract：OBJECTIVE:Dopamine transporter imaging with SPECT is a valuable tool for both clinical routine and research studies. Semi-quantitative analysis plays a key role in interpreting the scans, but is dependent on numerous factors, rotational radius being one of them. This study systematically evaluates the potential influen...

journal_title：Annals of nuclear medicine

authors： Koch W,Bartenstein P,la Fougère C

更新日期：2014-02-01 00:00:00

abstract：OBJECTIVE:We digested anti-MUC1 monoclonal antibody PR81 to produce F(ab')₂ fragments. A comparison was performed between the two radiolabeled PR81 and F(ab')₂ fragments for breast tumor imaging in a mouse model. METHODS:The optimum conditions for pepsin digestion of PR81 were investigated in terms of enzymes: antibod...

journal_title：Annals of nuclear medicine

authors： Salouti M,Babaei MH,Rajabi H,Foroutan H,Rasaee MJ,Rajabi AB,Mohammadnejad J,Shafiee M,Mazidi M,Daha FJ

更新日期：2011-02-01 00:00:00

abstract：:Alzheimer's disease (AD) is on the rise all over the world, and brings with it great challenges to medical care and heavy burdens to family and society. Accurate diagnosis and differential diagnosis are of great importance. Tau positron emission tomography (PET) might offer novel insights and be of great assistance in...

journal_title：Annals of nuclear medicine

authors： Zhang W,Xu S,Yu H,Li X,Jin Z,Li Y,He Z

更新日期：2021-01-18 00:00:00

abstract：:An early image of intra-tumor distribution of 14C-labeled fluorodeoxy glucose (14C-FDG) was compared with a late image of 18F-labeled FDG (18F-FDG) using mouse fibrosarcoma. Heterogeneous intra-tumor distribution of 14C-FDG was observed 1 minute post injection of the tracer, whereas relatively homogeneous distribution...

journal_title：Annals of nuclear medicine

authors： Inoue O,Shukuri M,Hosoi R,Amitani M,Matsuura N,Hatazawa J,Takai N

更新日期：2005-12-01 00:00:00

abstract：OBJECTIVE:To design, build, and evaluate an animal PET scanner, which can be used with non-human primates under conscious condition, incorporating flat-panel position-sensitive photomultiplier tubes (PS-PMTs). METHODS:The system contains 30 detector modules, each having two PS-PMTs and 16×18 lutetium–yttrium oxyortho-...

journal_title：Annals of nuclear medicine

authors： Okamoto T,Ote K,Sakai K,Noda A,Shimizu K,Masuda K,Ohmura T,Watanabe M

更新日期：2014-01-01 00:00:00

abstract：:A case of calcifying soft tissue malignant fibrous histiocytoma (MFH) which showed a concentration of Tc-99m MDP and Ga-67 citrate, is presented. Tc-99m MDP and Ga-67 citrate scintigraphies of the thigh mass were correlated with conventional radiography, computed tomography (CT) and angiography. ...

journal_title：Annals of nuclear medicine

authors： Kida T,Hoshi K,Hoshino R,Fujita Y,Munakata S,Yanagisawa M

更新日期：1993-02-01 00:00:00

abstract：:We compared single-sample methods, proposed by Russell et al. and Bubeck et al., and camera-based methods in calculating 99mTc-MAG3 clearance, and determined camera-based methods that provide estimates comparable to those measured by the Russell method. Twenty-one patients underwent 99mTc-MAG3 renal scintigraphy, and ...

journal_title：Annals of nuclear medicine

authors： Inoue Y,Yoshikawa K,Yokoyama I,Ohtomo K

更新日期：2000-10-01 00:00:00

abstract：UNLABELLED:We studied the causative mechanism of ampulla (Takotsubo) cardiomyopathy. METHODS:We examined 7 patients with ampulla cardiomyopathy by means of coronary angiography, two-dimensional echocardiography and 99Tc-tetrofosmin myocardial SPECT at the time of emergency admission (acute phase), at 3 to 5 days after...

journal_title：Annals of nuclear medicine

authors： Ito K,Sugihara H,Kawasaki T,Yuba T,Doue T,Tanabe T,Adachi Y,Katoh S,Azuma A,Nakagawa M

更新日期：2001-08-01 00:00:00

abstract：OBJECTIVE:Respiratory motion causes loss of image quality and inaccuracy of quantification in oncologic positron emission tomography (PET) imaging. This study introduces a bioimpedance-based gating method for compensation of respiratory motion artefacts. METHODS:The bioimpedance-based respiratory gating method was stu...

journal_title：Annals of nuclear medicine

authors： Koivumäki T,Teuho J,Teräs M,Vauhkonen M,Hakulinen MA

更新日期：2015-05-01 00:00:00