Abstract:
:Cerebral perfusion single photon emission computed tomography (SPECT) has been used to confirm the localization of the epileptic focus and the evaluation of seizure. Recently, diffusion-weighted MR imaging (DWI) has been recognized for evaluation of seizure activity. We describe a case of transient seizure activity demonstrated by Tc-99m HMPAO SPECT and DWI. This patient was a 61-year-old woman with a 10-month history of right middle cerebral artery (MCA) infarction who had a generalized seizure during MRI. DWI immediately after seizure showed transient hyperintensity in the right frontal gray matter and the white matter, and these apparent diffusion coefficients (ADC) were transiently decreased. This transient hyperintensity on DWI corresponded to transient hyperperfusion identifying the epileptic focus on interictal Tc-99m HMPAO SPECT. Transient sustained seizure activity might cause these changes on DWI and SPECT. It was considered that interictal Tc-99m HMPAO SPECT showed the delayed hyperperfusion caused by excitatory neuronal overaction and DWI showed cytotoxic edema seizure-induced by energy failure of the membrane-bound Na/K-ATPase pump.
journal_name
Ann Nucl Medjournal_title
Annals of nuclear medicineauthors
Sagiuchi T,Ishii K,Asano Y,Aoki Y,Woodhams R,Yanaihara H,Kan S,Hayakawa Kdoi
10.1007/BF02987844subject
Has Abstractpub_date
2001-06-01 00:00:00pages
267-70issue
3eissn
0914-7187issn
1864-6433journal_volume
15pub_type
杂志文章abstract:OBJECTIVE:To investigate whether [(11)C]PK-11195, a specific peripheral benzodiazepine receptors (PBRs) ligand for positron emission tomography (PET), can show activated microglia in a rat brain injury model. METHODS:On day 1, ethanol was injected into the rat's right striatum (ST) using a stereotaxic operative proced...
journal_title:Annals of nuclear medicine
pub_type: 杂志文章
doi:10.1007/s12149-008-0136-1
更新日期:2008-06-01 00:00:00
abstract:OBJECTIVE:One of the major causes of diabetes and obesity is abnormality in glucose metabolism and glucose uptake in the muscle and adipose tissue based on an insufficient action of insulin. Therefore, many of the drug discovery programs are based on the concept of stimulating glucose uptake in these tissues. Improveme...
journal_title:Annals of nuclear medicine
pub_type: 杂志文章
doi:10.1007/s12149-017-1169-0
更新日期:2017-06-01 00:00:00
abstract:OBJECTIVE:Variable uptake of 2-deoxy-2-[18F]fluoro-D-glucose (FDG) has been noticed in positron emission tomography (PET) studies of gastric carcinoma patients, with low uptake occurring especially in some particular histological subtypes and early carcinomas. But this phenomenon has not been adequately explained. The ...
journal_title:Annals of nuclear medicine
pub_type: 杂志文章
doi:10.1007/BF02984657
更新日期:2006-11-01 00:00:00
abstract::Metastatic calcification is often detected by bone scintigraphy. We recently saw metastatic calcification in the stomach and kidneys of a patient on continuous ambulatory peritoneal dialysis. Tc-99m HMDP accumulation into both organs was noted even in the first frame of dynamic data acquisition of 4 min/frame, suggest...
journal_title:Annals of nuclear medicine
pub_type: 杂志文章
doi:10.1007/BF03164806
更新日期:1996-11-01 00:00:00
abstract:OBJECTIVE:Because of the urinary excretion of fluorine-18 fluorodeoxyglucose ((18)F-FDG), FDG-PET or PET/CT is thought of little value in patients with bladder cancer. The purpose of our study was to investigate the value of (18)F-FDG PET/CT with additional pelvic images in detection of recurrent bladder cancers. METH...
journal_title:Annals of nuclear medicine
pub_type: 杂志文章
doi:10.1007/s12149-012-0614-3
更新日期:2012-08-01 00:00:00
abstract:OBJECTIVE:We digested anti-MUC1 monoclonal antibody PR81 to produce F(ab')₂ fragments. A comparison was performed between the two radiolabeled PR81 and F(ab')₂ fragments for breast tumor imaging in a mouse model. METHODS:The optimum conditions for pepsin digestion of PR81 were investigated in terms of enzymes: antibod...
journal_title:Annals of nuclear medicine
pub_type: 杂志文章
doi:10.1007/s12149-010-0434-2
更新日期:2011-02-01 00:00:00
abstract::We present a rare case of occult low-grade myofibroblastic sarcoma (LGMFS) detected by marked 2-[fluorine-18]-fluoro-2-deoxy-D-glucose (FDG) uptake on positron emission tomography (PET). A 46-year-old woman presented with abnormal FDG uptake in her back when FDG-PET was performed for cancer screening. The maximum stan...
journal_title:Annals of nuclear medicine
pub_type: 杂志文章
doi:10.1007/s12149-008-0194-4
更新日期:2008-11-01 00:00:00
abstract::To evaluate two methods for decreasing and/or diluting the FDG activity in the urinary system, five rats were intraperitoneally given 1,000 micrograms/g of L-lysine 4 times, starting from 60 minutes before iv injection of FDG, and then at 30-minute intervals for 90 minutes. Five rats were used as controls. In a furose...
journal_title:Annals of nuclear medicine
pub_type: 杂志文章
doi:10.1007/BF03164766
更新日期:1997-08-01 00:00:00
abstract:OBJECTIVES:Although dual-energy (DE) acquisition with conventional 201Tl myocardial perfusion SPECT has several advantages such as improved attenuation of the inferior wall and increased acquisition counts, the characteristics of IQ-SPECT have not been fully evaluated. We evaluate the difference of characteristics betw...
journal_title:Annals of nuclear medicine
pub_type: 杂志文章
doi:10.1007/s12149-017-1177-0
更新日期:2017-08-01 00:00:00
abstract:OBJECTIVE:We performed a bibliometric analysis of scientific publications focused on positron emission tomography (PET) over a 10-year period. METHODS:The MEDLINE and ISI Web of Knowledge databases were searched for English language original articles focused on PET in SCI/SCIE-indexed journals in 2002, 2007, and 2012....
journal_title:Annals of nuclear medicine
pub_type: 杂志文章
doi:10.1007/s12149-014-0836-7
更新日期:2014-06-01 00:00:00
abstract:OBJECTIVE:Anatomic relation between pulmonary perfusion and morphology in pulmonary emphysema was assessed on deep-inspiratory breath-hold (DIBrH) perfusion single-photon emission computed tomography (SPECT)-CT fusion images. METHODS:Subjects were 38 patients with pulmonary emphysema and 11 non-smoker controls, who su...
journal_title:Annals of nuclear medicine
pub_type: 杂志文章
doi:10.1007/s12149-007-0137-5
更新日期:2008-06-01 00:00:00
abstract::We are proposing a new method for correcting of scattered photons in technetium-99m (99mTc) imaging by means of photopeak dual-energy window acquisition. This method consists of the simultaneous acquisition of two images and estimation of a scatter image included in the symmetric energy window (SW) image by the differ...
journal_title:Annals of nuclear medicine
pub_type: 杂志文章
doi:10.1007/BF03178307
更新日期:1992-08-01 00:00:00
abstract::Bone scintigraphy is often performed to assess the response to systemic therapy of bone metastasis from prostate cancer. We examined the changes in bone scintigraphic findings and the agreement with AIP, AcP, or other tumor markers measured in the follow-up of patients with known bone metastasis after hormonal therapy...
journal_title:Annals of nuclear medicine
pub_type: 临床试验,杂志文章
doi:10.1007/BF03165024
更新日期:1994-11-01 00:00:00
abstract::16alpha-[(18)F]Fluoro-17beta-estradiol (FES) is an estrogen receptor (ER) ligand used for the detection of ER-positive malignant tumors such as breast cancer. We recently reported the feasibility of combined FES-and 2-[(18)F]fluoro-2-deoxy-D-glucose (FDG)-positron emission tomography (PET) scans for the differential d...
journal_title:Annals of nuclear medicine
pub_type: 杂志文章
doi:10.1007/s12149-007-0075-2
更新日期:2008-01-01 00:00:00
abstract:OBJECTIVE:Single-photon emission computed tomography (SPECT) using gallium (Ga) has been frequently used for diagnosing head and neck tumors in patients. Although the usefulness of Ga-SPECT is well known, the degree of the increase in diagnostic ability with Ga-SPECT for head and neck tumors has not been reported. We c...
journal_title:Annals of nuclear medicine
pub_type: 杂志文章
doi:10.1007/s12149-007-0116-x
更新日期:2008-05-01 00:00:00
abstract:PURPOSE:The purpose of this study was to evaluate whether the degree of technetium-99m methoxyisobutylisonitrile (MIBI) uptake and its retention in delayed imaging in small cell lung cancer (SCLC) was correlated with the response to multiagent chemotherapy and to investigate if there was a relationship between the surv...
journal_title:Annals of nuclear medicine
pub_type: 杂志文章
doi:10.1007/BF02984643
更新日期:2006-05-01 00:00:00
abstract:OBJECTIVE:Chemobrain is a recently proposed pathological entity. 18F-FDG PET/CT can show objective abnormalities to explain brain disorders caused by chemotherapy, although no study has investigated these phenomena in children to date. The main objective of the present study was to examine quantitatively the effects of...
journal_title:Annals of nuclear medicine
pub_type: 杂志文章
doi:10.1007/s12149-019-01363-8
更新日期:2019-08-01 00:00:00
abstract:OBJECTIVE:Radium-223 (223Ra) has been approved for treatment in patients with metastatic castration-resistant prostatic cancer (mCRPC) and bone metastasis. This α-emitting radionuclide has a beneficial effect on pain and is also capable to increase overall survival (OS). Several studies evaluated the prognostic value o...
journal_title:Annals of nuclear medicine
pub_type: 杂志文章
doi:10.1007/s12149-020-01501-7
更新日期:2020-10-01 00:00:00
abstract:BACKGROUND:The deep-inspiration breath-hold PET/CT (DIBH PET/CT) technique improves the limitations of diagnosing a lesion located in an area influenced by respiratory motion that results in spatial misregistrations caused by respiration between PET and CT. However, its reproducibility with regard to calculating the ma...
journal_title:Annals of nuclear medicine
pub_type: 杂志文章
doi:10.1007/s12149-010-0352-3
更新日期:2010-04-01 00:00:00
abstract::Despite using various kinds of prognostic indicators, it is still not possible to predict the biological behavior of breast cancer in all patients. Tc-99m-sestaMIBI (MIBI) uptake determined by breast scintigraphy and cadherin expression of tumor tissue revealed by immunohistochemistry are suggested as potential agents...
journal_title:Annals of nuclear medicine
pub_type: 杂志文章
doi:10.1007/BF02988522
更新日期:2003-06-01 00:00:00
abstract:OBJECTIVE:Respiratory motion causes loss of image quality and inaccuracy of quantification in oncologic positron emission tomography (PET) imaging. This study introduces a bioimpedance-based gating method for compensation of respiratory motion artefacts. METHODS:The bioimpedance-based respiratory gating method was stu...
journal_title:Annals of nuclear medicine
pub_type: 杂志文章
doi:10.1007/s12149-015-0953-y
更新日期:2015-05-01 00:00:00
abstract::Using the fuzzy set theory, a method was developed for analyzing the extent and severity of ischemia by comparing the exercise and delayed SPECT images with Thallium-201. For each short axial image (slice) for exercise and delayed study, a defect probability matrix (DPM) is created so that it shows the severity of isc...
journal_title:Annals of nuclear medicine
pub_type: 杂志文章
doi:10.1007/BF03164947
更新日期:1988-11-01 00:00:00
abstract:OBJECTIVE:This study aims to determine whether a (131)I double-phase whole body scan (WBS) and SPECT-CT images have added value over a single-phase WBS image in identifying benign and malignant lesions in patients with well-differentiated thyroid cancer (DTC) at their first radioactive iodine (RAI) treatment. METHODS:...
journal_title:Annals of nuclear medicine
pub_type: 杂志文章
doi:10.1007/s12149-011-0513-z
更新日期:2011-11-01 00:00:00
abstract:AIM:To assess the predictive and prognostic value of textural parameters in locally advanced breast cancer (LABC) obtained by 18F-FDG PET/CT. METHODS:Prospective study including 68 patients with LABC, neoadjuvant chemotherapy (NC) indication and a baseline 18F-FDG PET/CT. Breast specimens were grouped into molecular p...
journal_title:Annals of nuclear medicine
pub_type: 杂志文章
doi:10.1007/s12149-018-1253-0
更新日期:2018-07-01 00:00:00
abstract:OBJECTIVE:Radium-223 (223Ra) is used in unsealed radionuclide therapy for metastatic bone tumors. The aim of this study is to apply a computational model observer to 223Ra planar images, and to assess the performance of collimators in 223Ra imaging. METHODS:The 223Ra planar images were created via an in-house Monte Ca...
journal_title:Annals of nuclear medicine
pub_type: 杂志文章
doi:10.1007/s12149-018-1286-4
更新日期:2018-12-01 00:00:00
abstract:OBJECTIVE:Dopamine transporter imaging with SPECT is a valuable tool for both clinical routine and research studies. Semi-quantitative analysis plays a key role in interpreting the scans, but is dependent on numerous factors, rotational radius being one of them. This study systematically evaluates the potential influen...
journal_title:Annals of nuclear medicine
pub_type: 杂志文章
doi:10.1007/s12149-013-0789-2
更新日期:2014-02-01 00:00:00
abstract:OBJECTIVES:Split renal function (SRF) estimated from the posterior view of (99m)Tc-diethylenetriaminepentaacetic acid planar scintigraphy (DTPA/P) is not sufficiently accurate even after correction for kidney depth by computed tomography (CT). To obtain more accurate SRF using (99m)Tc-DTPA, dynamic SPECT method was car...
journal_title:Annals of nuclear medicine
pub_type: 杂志文章
doi:10.1007/s12149-010-0349-y
更新日期:2010-04-01 00:00:00
abstract:OBJECTIVE:The FDG uptake in lung cancer is considered to reflect the degree of malignancy, while alterations of some tumor suppressor genes are considered to be related to the malignant biological behavior of tumors. The aim of this study is to examine the relationship between FDG-PET and alterations in the tumor suppr...
journal_title:Annals of nuclear medicine
pub_type: 临床试验,杂志文章
doi:10.1007/BF02990021
更新日期:2003-05-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to perform a systematic review of the prognostic value of texture parameters derived by 18F-fluorodeoxyglucose positron emission tomography (18F-FDG PET) in patients with lung cancer. METHODS:PubMed and EMBASE databases were searched up to March 12, 2018, for original articles invol...
journal_title:Annals of nuclear medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1007/s12149-018-1281-9
更新日期:2018-11-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to assess I-131 biokinetics in thyroid cancer and remnant tissue in patients with differentiated thyroid cancer using whole-body scan (WBS) and SPECT images acquired after I-131 therapy. The influence of thyroid stimulating hormone (TSH) stimulation method on the kinetics was also ev...
journal_title:Annals of nuclear medicine
pub_type: 杂志文章
doi:10.1007/s12149-017-1188-x
更新日期:2017-10-01 00:00:00