Alterations of tumor suppressor genes (Rb, p16, p27 and p53) and an increased FDG uptake in lung cancer.

abstract：OBJECTIVE:Epidermal growth factor receptor tyrosine kinase (EGFR-TK) represents an attractive target for tumor diagnosis agents. Previously, radioiodinated 4-(3-iodophenoxy)-6,7-diethoxyquinazoline (PHY) was reported to possess good characteristics as a tumor imaging agent. We have explored the feasibility of developin...

journal_title：Annals of nuclear medicine

authors： Hirata M,Kanai Y,Naka S,Yoshimoto M,Kagawa S,Matsumuro K,Katsuma H,Yamaguchi H,Magata Y,Ohmomo Y

更新日期：2013-06-01 00:00:00

abstract：:Myocardial normal databases for stress myocardial perfusion study have been created by the Japanese Society of Nuclear Medicine Working Group. The databases comprised gender-, camera rotation range- and radiopharmaceutical-specific data-sets from multiple institutions, and normal database files were created for instal...

journal_title：Annals of nuclear medicine

authors： Nakajima K

更新日期：2010-04-01 00:00:00

abstract：PURPOSE:Treatment effect of radiofrequency ablation (RFA) is traditionally accomplished with MRI and/or CT. The aim of the study was to assess the role of FDG-PET in post RFA hepatic tumor evaluation, in comparison with MRI and CT. MATERIALS AND METHODS:28 patients (33 hepatic RFA lesions) who had post RFA FDG-PET wit...

journal_title：Annals of nuclear medicine

authors： Chen W,Zhuang H,Cheng G,Torigian DA,Alavi A

更新日期：2013-01-01 00:00:00

abstract：:Osmotic demyelination syndrome can result from the rapid correction of hyponatremia, and is categorized by central pontine myelinolysis and extrapontine myelinolysis (EPM). Magnetic resonance imaging (MRI) is currently the most useful modality for visualizing EPM lesions. However, MRI is unable to delineate the severi...

journal_title：Annals of nuclear medicine

authors： Wu YC,Peng GS,Cheng CA,Lin CC,Huang WS,Hsueh CJ,Lee JT

更新日期：2009-06-01 00:00:00

abstract：:Identification and treatment of hibernating myocardium (HM) lead to improvement in LV function and prognosis in patients with post-ischemic heart failure. Different techniques are used to diagnose HM: echocardiography, MRI, SPECT and PET and, in patients with moderate LV impairment, their predictive values are similar...

journal_title：Annals of nuclear medicine

authors： Camici PG,Rimoldi OE

更新日期：2003-07-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to elucidate the causes of false-negative cases of technetium-99 m methoxyisobutylisonitrile scintigraphy (MIBI) for hyperparathyroidism. METHODS:Consecutive MIBI examinations performed in 154 patients between April 2011 and March 2017 were retrospectively reviewed. Sensitivities of...

journal_title：Annals of nuclear medicine

authors： Ishii S,Sugawara S,Yaginuma Y,Kobiyama H,Hiruta M,Watanabe H,Yamakuni R,Hakozaki M,Fujimaki H,Ito H

更新日期：2020-12-01 00:00:00

abstract：OBJECTIVE:While high-energy gamma and beta probes have gained considerable attention due to their ability to detect cancerous lesions using (18)F-FDG in humans intraoperatively, it is unknown whether the sensitivity of such probes would allow the detection of remaining tumor tissue in the resection bed after removal of...

journal_title：Annals of nuclear medicine

authors： Garcia-Parra R,Clinthorne N,Wang L,Picchio M,Piert M

更新日期：2011-08-01 00:00:00

abstract：:Most of the acute ischemic events, such as acute coronary syndromes and stroke, are attributed to vulnerable plaques. These lesions have common histological and pathophysiological features, including inflammatory cell infiltration, neo-angiogenesis, remodelling, haemorrhage predisposition, thin fibrous cap, large lipi...

journal_title：Annals of nuclear medicine

authors： Giannakou S,Angelidis G,Tsougos I,Valotassiou V,Kappas K,Georgoulias P

更新日期：2020-05-01 00:00:00

abstract：:Technetium-99m tetrofosmin and thallium-201 lung SPECT imaging were performed in a patient with adenocarcinoma of the lung. Significant activities in the lung lesion were clearly depicted on both technetium-99m tetrofosmin and thallium-201 SPECT imaging. The early uptake, delayed uptake ratios and retention indices of...

journal_title：Annals of nuclear medicine

authors： Matsunari I,Kinuya S,Nishikawa T,Matoba M,Murakita K,Ohguchi M,Ichiyanagi K,Taki J,Tonami N,Hisada K

更新日期：1996-02-01 00:00:00

abstract：OBJECTIVE:Fluorine-18 fluorodeoxyglucose (FDG)-positron emission tomography (PET) and PET/computed tomography (PET/CT) have had a considerable impact on the detection of various malignancies. PET and PET/CT are minimally invasive methods that can provide whole-body imaging at one time. Therefore, an FDG-PET cancer scre...

journal_title：Annals of nuclear medicine

authors： Yamamoto Y,Tasaki Y,Kuwada Y,Ozawa Y,Inoue T

更新日期：2016-02-01 00:00:00

abstract：:In practical positron emission tomography (PET) diagnosis, a shortened protocol is preferred for patients with brain disorders. In this study, the applicability of a shortened protocol as an alternative to the 90-min PET scan with [(11)C]SA4503 for quantitative sigma(1) receptor measurement was investigated. Tissue ti...

journal_title：Annals of nuclear medicine

authors： Sakata M,Kimura Y,Naganawa M,Ishikawa M,Oda K,Ishii K,Hashimoto K,Chihara K,Ishiwata K

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND:Aortic knob width on chest radiography represents the extent of aortic dialation and tortuosity of the aortic arch. We tested the hypothesis that aortic knob width reflected left ventricular (LV) diastolic function assessed by gated myocardial perfusion single photon emission computed tomography (SPECT) in p...

journal_title：Annals of nuclear medicine

authors： Kurisu S,Higaki T,Sumimoto Y,Ikenaga H,Watanabe N,Ishibashi K,Dohi Y,Fukuda Y,Kihara Y

更新日期：2017-04-01 00:00:00

abstract：:This study evaluates the regional cerebral blood flow (CBF) with H2(15)O-PET and the distribution of central benzodiazepine receptor (BZR) with C-11 flumazenil (FMZ) by PET and I-123 iomazenil (IMZ) by SPECT in Alzheimer's disease (AD). In AD, whereas the CBF was diminished in the frontal, temporal, parietal, and occi...

journal_title：Annals of nuclear medicine

authors： Ohyama M,Senda M,Ishiwata K,Kitamura S,Mishina M,Ishii K,Toyama H,Oda K,Katayama Y

更新日期：1999-10-01 00:00:00

abstract：UNLABELLED:To determine the utility of the myocardial tracer Tc-99m-tetrofosmin in the examination of patients with left bundle branch block (LBBB) and to investigate Tc-99m-tetrofosmin uptake and retention in the myocardium, early and delayed Tc-99m-tetrofosmin SPECT was performed in 10 patients having LBBB without co...

journal_title：Annals of nuclear medicine

authors： Sugihara H,Kinoshita N,Adachi Y,Taniguchi Y,Ohtsuki K,Azuma A,Adachi H,Ushijima Y,Nakagawa M,Maeda T

更新日期：1998-10-01 00:00:00

abstract：OBJECTIVE:The main aim of this work is to build a robust Convolutional Neural Network (CNN) algorithm that efficiently and quickly classifies bone scintigraphy images, by determining the presence or absence of prostate cancer metastasis. METHODS:CNN, widely applied in medical image classification, was used for bone sc...

journal_title：Annals of nuclear medicine

authors： Papandrianos N,Papageorgiou EI,Anagnostis A

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVE:This study aims to determine whether a (131)I double-phase whole body scan (WBS) and SPECT-CT images have added value over a single-phase WBS image in identifying benign and malignant lesions in patients with well-differentiated thyroid cancer (DTC) at their first radioactive iodine (RAI) treatment. METHODS:...

journal_title：Annals of nuclear medicine

authors： Wakabayashi H,Nakajima K,Fukuoka M,Inaki A,Nakamura A,Kayano D,Kinuya S

更新日期：2011-11-01 00:00:00

abstract：:We evaluated the potential of sodium [1-(11)C]hexanoate (11C-HA) as a radiopharmaceutical with which to assess oxidative metabolism of the brain by PET. 11C-HA, sodium [1-(14)C]acetate and [3H]deoxyglucose were simultaneously injected into mice under control, hypoxic and starving conditions. In the control, the brain ...

journal_title：Annals of nuclear medicine

authors： Ishiwata K,Ishii K,Ogawa K,Nozaki T,Senda M

更新日期：1996-05-01 00:00:00

abstract：:We report a case of myocardial stunning after acute myocardial infarction. In the hyperacute phase of myocardial infarction, the patient's coronary arteries showed normal features on coronary angiography during extensive ST-segment elevation observed on a standard 12-lead electrocardiogram and extensive akinesis obser...

journal_title：Annals of nuclear medicine

authors： Sakata K,Yoshida H,Ono N,Matsunaga Y,Hoshino T,Kaburagi T,Mochizuki M,Yoshimura M

更新日期：1994-05-01 00:00:00

abstract：:We report a functional neuroimaging study of a patient clinically diagnosed with Korsakoff syndrome. Positron emission tomography (PET) with the 15O inhalation method showed decreased regional cerebral blood flow (rCBF) and decreased regional cerebral metabolic ratio for oxygen (rCMRO2) in the bilateral fronto-tempora...

journal_title：Annals of nuclear medicine

authors： Matsuda K,Yamaji S,Ishii K,Sasaki M,Sakamoto S,Kitagaki H,Imamura T,Mori E

更新日期：1997-02-01 00:00:00

abstract：AIM:The purpose of the study was to determine the lung toxicity caused by amiodarone (AD) and bleomycin (BLM) in rats, by means of Tc-99m HMPAO lung scintigraphy. METHODS:Thirty albino rats were randomly divided into five groups. After AD or BLM was dissolved with isotonic saline (SF), a 0.5 ml solution was applied to...

journal_title：Annals of nuclear medicine

authors： Gumuser G,Vural K,Varol T,Parlak Y,Tuglu I,Topal G,Sayit E

更新日期：2013-08-01 00:00:00

abstract：AIM:18F-Choline (FCH) uptake parameters are strong indicators of aggressive disease in prostate cancer. Functional parameters derived by magnetic resonance imaging (MRI) are also correlated to aggressive disease. The aim of this work was to evaluate the relationship between metabolic parameters derived by FCH PET/CT an...

journal_title：Annals of nuclear medicine

authors： Palard-Novello X,Beuzit L,Gambarota G,Le Jeune F,Garin E,Salaün PY,Devillers A,Querellou S,Bourguet P,Saint-Jalmes H

更新日期：2019-01-01 00:00:00

abstract：:Pyothorax-associated lymphoma (PAL) is a non-Hodgkin's lymphoma developing in the pleural cavity after a long-standing history of chronic pyothorax (CP). F-18 fluorodeoxyglucose positron emission tomography (FDG-PET) imaging is a useful modality for determination of disease extent of various malignant tumors, includin...

journal_title：Annals of nuclear medicine

authors： Asakura H,Togami T,Mitani M,Takashima H,Yokoe K,Yamamoto Y,Nishiyama Y,Monden T,Toyama Y,Ohkawa M

更新日期：2005-12-01 00:00:00

abstract：:The aim of the present study was to assess the predictive value of captopril scintigraphy with the new renal agent 99mTc-ethylenedicysteine (99mTc-EC) for post-interventional improvement in blood pressure. Twelve patients who had persistently high blood pressure with previous demonstration of various degrees of renal ...

journal_title：Annals of nuclear medicine

authors： Uğur O,Serdengeçti M,Karacalioğlu O,Ergün EL,Peksoy I,Cekirge S

更新日期：1999-04-01 00:00:00

abstract：:A rare case of inferior vena cava (IVC) thrombosis and pulmonary embolism secondary to acute exacerbation of chronic pancreatitis was reported. Radionuclide venography and lung perfusion scintigraphy were performed on a 46-year-old male with acute exacerbation of chronic pancreatitis who complained of mild swelling of...

journal_title：Annals of nuclear medicine

authors： Ohta H,Hachiya T

更新日期：2002-04-01 00:00:00

abstract：OBJECTIVE:Because thickening of the gallbladder wall is observed not only in patients with gallbladder cancer but also in those with benign diseases such as chronic cholecystitis and gallbladder adenomyosis, it is difficult to distinguish between benign and malignant gallbladder wall thickening by conventional techniqu...

journal_title：Annals of nuclear medicine

authors： Oe A,Kawabe J,Torii K,Kawamura E,Higashiyama S,Kotani J,Hayashi T,Kurooka H,Tsumoto C,Kubo S,Shiomi S

更新日期：2006-12-01 00:00:00

abstract：AIM:To investigate the diagnostic performance of early acquisition compared to late imaging for the detection of local recurrence of prostate cancer by means of ¹⁸F-FCH PET/CT. MATERIALS AND METHODS:99 patients with radical prostatectomy (mean PSA 3.9 ± 5.03) were subjected to early dynamic PET/CT acquisition of the p...

journal_title：Annals of nuclear medicine

authors： Di Biagio D,Chiaravalloti A,Tavolozza M,Abbatiello P,Schillaci O

更新日期：2015-12-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to investigate the effects of computed tomography (CT) artifacts caused by dental metal prostheses on positron emission tomography (PET) images. METHODS:A dental arch cast was fixed in a cylindrical water-bath phantom. A spherical phantom positioned in the vicinity of the dent...

journal_title：Annals of nuclear medicine

authors： Shimamoto H,Kakimoto N,Fujino K,Hamada S,Shimosegawa E,Murakami S,Furukawa S,Hatazawa J

更新日期：2009-07-01 00:00:00

abstract：OBJECTIVE:Among different PET tracers, 18F-fludeoxyglucose (FDG) and 11C-choline are known to have a high tumor uptake correlated with a high mitotic index of tumor cells. Thus, the uptake of 18F-FDG and 11C-choline may be dependent on the cell cycle. In the present study, we examined the uptake of 18F-FDG and 11C-chol...

journal_title：Annals of nuclear medicine

authors： Roppongi M,Izumisawa M,Terasaki K,Muraki Y,Shozushima M

更新日期：2019-04-01 00:00:00

abstract：:Tuberculosis peritonitis is a rare manifestation of extrapulmonary tuberculosis. The results of gallium-67 scintigraphy of three patients with tuberculosis peritonitis were reviewed to assess its usefulness in the diagnosis of this condition. Tuberculosis peritonitis was associated with diffuse or focal abdominal loca...

journal_title：Annals of nuclear medicine

authors： Sumi Y,Ozaki Y,Hasegawa H,Shindoh N,Katayama H,Tamamoto F

更新日期：1999-06-01 00:00:00

abstract：UNLABELLED:We propose a new method to quantify regional myocardial blood flow (rMBF) by continuous infusion of Tc-99m MIBI and dynamic SPECT. METHODS:Five patients with old myocardial infarction were studied. During continuous infusion of MIBI (approximately 740 MBq) with a syringe pump in 10 min, dynamic SPECT scan w...

journal_title：Annals of nuclear medicine

authors： Tsuchida T,Yonekura Y,Takahashi N,Nakano A,Lee JD,Sadato N,Yamamoto K,Waki A,Sugimoto K,Hayashi N,Ishii Y

更新日期：1999-02-01 00:00:00