Abstract：
OBJECTIVE:Fluorine-18 fluorodeoxyglucose (FDG)-positron emission tomography (PET) and PET/computed tomography (PET/CT) have had a considerable impact on the detection of various malignancies. PET and PET/CT are minimally invasive methods that can provide whole-body imaging at one time. Therefore, an FDG-PET cancer screening program has been widely used in Japan. However, the breast cancer detection rate of FDG-PET cancer screening is relatively low. Therefore, FDG-PET screening is not recommended for breast cancer screening. Positron emission mammography (PEM) is a high-resolution molecular breast imaging technology. PEM can detect small breast cancers that cannot be detected on PET or PET/CT images due to limited spatial resolution. We have performed opportunistic breast cancer screening using PEM since 2011. To the best of our knowledge, this is the first report regarding PEM breast cancer screening. METHODS:This study enrolled 265 women. PEM images were analyzed by agreement of 2 experienced nuclear medicine physicians. The readers were given information from medical interview sheet. US findings were interpreted holistically. The number of participants, patient recall rate, further examination rate, and cancer detection rate by year were calculated. RESULTS:The overall recall rate was 8.3%; the work-up examination rate was 77.3%, and cancer detection rate was 2.3%. The positive predictive value of PEM was 27.3%. Six cancers were found by PEM screening. Five were invasive cancers and one was ductal carcinoma in situ. Histological tumor sizes were reported in three cases: 0.7, 1.2, and 2 cm. CONCLUSION:PEM screening appears to have potential for breast cancer screening.
journal_name
Ann Nucl Medjournal_title
Annals of nuclear medicineauthors
Yamamoto Y,Tasaki Y,Kuwada Y,Ozawa Y,Inoue Tdoi
10.1007/s12149-015-1040-0subject
Has Abstractpub_date
2016-02-01 00:00:00pages
130-7issue
2eissn
0914-7187issn
1864-6433pii
10.1007/s12149-015-1040-0journal_volume
30pub_type
杂志文章abstract：:We report scan findings of Tl-201 in a case of histologically proved Warthin's tumor. Dual isotopes acquisition was performed in a case of left parotid Warthin's tumor. Both early and delayed Tc-99m-pertechnetate (Tc-99m) images showed increased uptake at the tumor. Tl-201 scan also showed an increase of uptake on the...
journal_title：Annals of nuclear medicine
pub_type： 杂志文章
doi：10.1007/BF03164741
更新日期：1996-08-01 00:00:00
abstract：OBJECTIVE:Positron emission tomography (PET) angiography utilizes early dynamic PET acquisitions for depiction of the arterial vasculature. The aim of this study was to assess image quality and to evaluate feasibility of F-18 FDG PET angiography of the abdominal arteries. METHODS:Twenty-seven patients were included in...
journal_title：Annals of nuclear medicine
pub_type： 杂志文章
doi：10.1007/s12149-014-0930-x
更新日期：2015-02-01 00:00:00
abstract：OBJECTIVE:The potential of positron emission tomography/computed tomography using 62Cu-diacetyl-bis (N4-methylthiosemicarbazone) (62Cu-ATSM PET/CT), which was originally developed as a hypoxic tracer, to predict therapeutic resistance and prognosis has been reported in various cancers. Our purpose was to investigate pr...
journal_title：Annals of nuclear medicine
pub_type： 临床试验,杂志文章
doi：10.1007/s12149-018-1241-4
更新日期：2018-05-01 00:00:00
abstract：:We studied the cerebral muscarinic acetylcholinergic receptor (mACh-R) by means of 11C-N-methyl-4-piperidyl benzilate (11C-NMPB) and positron emission tomography (PET) in Alzheimer's disease (AD) cases, and the findings were compared with the cerebral blood flow (CBF) and the glucose metabolism (CMRGlc) to evaluate th...
journal_title：Annals of nuclear medicine
pub_type： 杂志文章
doi：10.1007/BF03165414
更新日期：1998-02-01 00:00:00
abstract：:We quantitated the protective effect of verapamil on reperfusion injury in canine myocardial infarct using 111In-anticardiac myosin antibody and correlated to the electronmicroscopic findings. Experimental myocardial infarction was performed by one hour occlusion of the anterior descending coronary artery and followed...
journal_title：Annals of nuclear medicine
pub_type： 杂志文章
doi：10.1007/BF03164623
更新日期：1991-09-01 00:00:00
abstract：:Nuclear Medicine is the specialty of medical imaging, which utilizes a variety of radionuclides incorporated into specific compounds for diagnostic imaging and therapeutic applications. During recent years, research efforts in this discipline have concentrated on the decay characteristics of particular radionuclides a...
journal_title：Annals of nuclear medicine
pub_type： 杂志文章,评审
doi：10.1007/BF03164930
更新日期：1999-12-01 00:00:00
abstract：OBJECTIVE:Lung clearance rates of inhaled (99m)Tc-DTPA aerosols constitute a sensitive index to evaluate the permeability changes characteristic of airway epithelial damage. It was thought that edema of the airway wall which is reported in asthma could be relieved with a diuretic like furosemide, helping to relieve the...
journal_title：Annals of nuclear medicine
pub_type： 临床试验,杂志文章
doi：10.1007/s12149-009-0275-z
更新日期：2009-08-01 00:00:00
abstract：OBJECTIVE:The aim of the study was to investigate the outcomes and prognostic factors of high-dose 131I-metaiodobenzylguanidine (131I-MIBG) therapy in patients with refractory or relapsed neuroblastoma (NBL) in Japan. METHODS:We retrospectively analyzed 20 patients with refractory or relapsed high-risk NBL who underwe...
journal_title：Annals of nuclear medicine
pub_type： 杂志文章
doi：10.1007/s12149-020-01460-z
更新日期：2020-06-01 00:00:00
abstract：OBJECTIVE:Estimation of nonlinear micro-parameters is a computationally demanding and fairly challenging process, since it involves the use of rather slow iterative nonlinear fitting algorithms and it often results in very noisy voxel-wise parametric maps. Direct reconstruction algorithms can provide parametric maps wi...
journal_title：Annals of nuclear medicine
pub_type： 杂志文章
doi：10.1007/s12149-014-0881-2
更新日期：2014-11-01 00:00:00
abstract：:Filtered back projection (FBP) method, maximum likelihood-expectation maximization(ML-EM) method, and ordered subsets-expectation maximization (OS-EM) method are currently used for reconstruction of SPECT images in clinical studies. In the ML-EM method, images of good quality can be reconstructed even with a small sam...
journal_title：Annals of nuclear medicine
pub_type： 杂志文章
doi：10.1007/BF03006664
更新日期：2003-10-01 00:00:00
abstract：:We reviewed the findings of adrenocortical scintigraphy with 131I-6-beta-iodomethyl-19-norcholesterol (NCL-6-131I) of 39 patients to clarify its role in the evaluation of unilateral adrenal or juxtaadrenal masses incidentally discovered by CT, ultrasonography or plain radiography. Twenty-seven benign adrenal masses sh...
journal_title：Annals of nuclear medicine
pub_type： 杂志文章
doi：10.1007/BF03164960
更新日期：1993-08-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to evaluate the value of breast-specific gamma imaging (BSGI) as compared with mammography (MMG) and ultrasonography (US). METHODS:This study retrospectively enrolled 121 women with breast cancer (45.0 ± 8.1 years) and dense breasts (breast density >50 %). All patients underwent pre...
journal_title：Annals of nuclear medicine
pub_type： 杂志文章
doi：10.1007/s12149-012-0649-5
更新日期：2012-12-01 00:00:00
abstract：OBJECTIVE:(11)C-Methionine positron emission tomography (MET-PET) has been used to distinguish brain tumor recurrence from radiation necrosis. Because the spatial resolution of conventional PET scanners is low, partial volume effect (PVE) may decrease the detectability of small tumor recurrence. The aim of this study i...
journal_title：Annals of nuclear medicine
pub_type： 杂志文章
doi：10.1007/s12149-010-0450-2
更新日期：2011-04-01 00:00:00
abstract：UNLABELLED:The purpose of this study is to determine the subcellular distribution of thallium (SDTl) by electron microscopy and a newly designed fixation method that makes insoluble grains of Tl visible. METHODS:To obtain the high dose necessary for electron microscopic visualization, we employed TlCl instead of 201Tl...
journal_title：Annals of nuclear medicine
pub_type： 杂志文章
doi：10.1007/BF03165296
更新日期：1997-11-01 00:00:00
abstract：OBJECTIVE:This study aimed to determine changes in FDG-PET/CT after pleurodesis with OK-432 and to investigate differences in the changes between non-malignant and malignant lesions. METHODS:Study participants were 17 patients with a history of malignant chest disease who underwent FDG-PET/CT after pleurodesis using O...
journal_title：Annals of nuclear medicine
pub_type： 杂志文章
doi：10.1007/s12149-020-01508-0
更新日期：2020-10-01 00:00:00
abstract：:Written by associate editors of the Annals of Nuclear Medicine, this invited review article is intended to offer our readers a condensed global view on the high-quality research work that has been published in Europe last year. We have divided this article into five sections. The first three sections from the oncology...
journal_title：Annals of nuclear medicine
pub_type： 杂志文章,评审
doi：10.1007/s12149-018-1303-7
更新日期：2018-11-01 00:00:00
abstract：OBJECTIVES:We compared the diagnostic value of fluorine-18-fluorodeoxyglucose positron emission tomography (FDG-PET) with that of computed tomography (CT) following radiofrequency ablation (RFA) of inoperable recurrent or metastatic cancers in the lung. METHODS:Twelve patients (9 males and 3 females; 5 had recurrent l...
journal_title：Annals of nuclear medicine
pub_type： 临床试验,杂志文章
doi：10.1007/BF02985623
更新日期：2006-02-01 00:00:00
abstract：OBJECTIVE:Metabolic tumor burden (MTB) incorporates the advantages of the existing indices: the metabolic volume of the lesion calculated by size-dependent thresholding on positron emission tomography-computed tomography (PET-CT) along with its aggressiveness as determined by standardized uptake value (SUV). This study...
journal_title：Annals of nuclear medicine
pub_type： 杂志文章
doi：10.1007/s12149-011-0539-2
更新日期：2012-01-01 00:00:00
abstract：OBJECTIVE:The performance characteristics of the SPECT sub-system S102 of the ALBIRA II PET/SPECT/CT are analyzed for the 80 mm field of view (FOV) to evaluate the potential in-vivo imaging in rats, based on measurements of the system response for the commonly used Technetium-99 m (99mTc) in small animal imaging. METH...
journal_title：Annals of nuclear medicine
pub_type： 杂志文章
doi：10.1007/s12149-020-01547-7
更新日期：2021-01-01 00:00:00
abstract：PURPOSE:Esophageal complication is common in systemic sclerosis (SSc), but scintigraphic transit patterns based on each subtype have not been understood well. The aim of this study was to develop a new algorithm for integrating a dynamic esophageal transit study and to apply the method to patients with SSc. METHODS:A ...
journal_title：Annals of nuclear medicine
pub_type： 杂志文章
doi：10.1007/s12149-011-0465-3
更新日期：2011-06-01 00:00:00
abstract：:The aim of the present study was to assess the predictive value of captopril scintigraphy with the new renal agent 99mTc-ethylenedicysteine (99mTc-EC) for post-interventional improvement in blood pressure. Twelve patients who had persistently high blood pressure with previous demonstration of various degrees of renal ...
journal_title：Annals of nuclear medicine
pub_type： 杂志文章
doi：10.1007/BF03164881
更新日期：1999-04-01 00:00:00
abstract：:Global and regional myocardial uptake was determined with technetium-99m tetrofosmin and a 4 hour exercise (370 MBq i.v.) and rest (740 MBq i.v.) protocol, in 24 patients with non-insulin dependent diabetes mellitus and in 22 control subjects. The purpose of this study was to evaluate impaired coronary microvascular f...
journal_title：Annals of nuclear medicine
pub_type： 杂志文章
doi：10.1007/BF02987855
更新日期：2000-06-01 00:00:00
abstract：OBJECTIVE:123I-metaiodobenzylguanidine (MIBG) myocardial scintigraphy is currently used to evaluate cardiac sympathetic nerve function, but MIBG also has the capacity to evaluate dilated cardiomyopathy (DCM) severity and therapeutic effectiveness. In this study, we administered beta-blockers to a DCM hamster model and ...
journal_title：Annals of nuclear medicine
pub_type： 杂志文章
doi：10.1007/BF02984974
更新日期：2003-12-01 00:00:00
abstract：AIM:To assess the predictive and prognostic value of textural parameters in locally advanced breast cancer (LABC) obtained by 18F-FDG PET/CT. METHODS:Prospective study including 68 patients with LABC, neoadjuvant chemotherapy (NC) indication and a baseline 18F-FDG PET/CT. Breast specimens were grouped into molecular p...
journal_title：Annals of nuclear medicine
pub_type： 杂志文章
doi：10.1007/s12149-018-1253-0
更新日期：2018-07-01 00:00:00
abstract：OBJECTIVE:Radio-guided sentinel node (SN) biopsy is a standard method used in the treatment of early breast cancer. Single photon emission computed tomography with computed tomography (SPECT/CT) has been commonly used for SN detection. SPECT/CT adds precise anatomical information of SN sites, and it is reported that mo...
journal_title：Annals of nuclear medicine
pub_type： 杂志文章
doi：10.1007/s12149-018-1319-z
更新日期：2019-03-01 00:00:00
abstract：PURPOSE:The quality of images reconstructed by means of the maximum likelihood-expectation maximization (ML-EM) and ordered subset (OS)-EM algorithms, was examined with parameters such as the number of iterations and subsets, then compared with the quality of images reconstructed by the filtered back projection method....
journal_title：Annals of nuclear medicine
pub_type： 杂志文章
doi：10.1007/BF02988506
更新日期：2001-12-01 00:00:00
abstract：AIM:The purpose of the study was to determine the lung toxicity caused by amiodarone (AD) and bleomycin (BLM) in rats, by means of Tc-99m HMPAO lung scintigraphy. METHODS:Thirty albino rats were randomly divided into five groups. After AD or BLM was dissolved with isotonic saline (SF), a 0.5 ml solution was applied to...
journal_title：Annals of nuclear medicine
pub_type： 杂志文章
doi：10.1007/s12149-013-0722-8
更新日期：2013-08-01 00:00:00
abstract：:We recently experienced a case with uveitis suffering from fever of unknown origin suspected of being caused by sarcoidosis. Chest computed tomography showed right supraclavicular, bilateral mediastinal, and right hilar lymphadenopathy, and intensive abnormal uptake of 2-[18F]fluoro-2-deoxy-D-glucose (18F-FDG) was obs...
journal_title：Annals of nuclear medicine
pub_type： 杂志文章
doi：10.1007/s12149-007-0037-8
更新日期：2007-08-01 00:00:00
abstract：OBJECTIVES:Nowadays, the number of primary studies on fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) has been increasing rapidly. Thus, we updated meta-analysis to evaluate the test performance of FDG PET/CT for nodal staging in non-small cell lung cancer (NSCLC) including the most r...
journal_title：Annals of nuclear medicine
pub_type： 杂志文章,meta分析
doi：10.1007/s12149-015-0958-6
更新日期：2015-06-01 00:00:00
abstract：:(-)-O-Methylvesamicol ((-)-OMV) exhibited in vitro a high affinity for vesicular acetylcholine transporter (VAChT) (Ki, 6.7 nM) and a relatively low affinity for sigmal receptor (Ki, 33.7 nM). We prepared (-)-[11C]OMV by a palladium-promoted cross-coupling reaction using [11C]methyl iodide, in a radiochemical yield of...
journal_title：Annals of nuclear medicine
pub_type： 杂志文章
doi：10.1007/BF03027377
更新日期：2006-07-01 00:00:00
