Comparison between single photon emission computed tomography with computed tomography and planar scintigraphy in sentinel node biopsy in breast cancer patients.

Abstract:

OBJECTIVE:Radio-guided sentinel node (SN) biopsy is a standard method used in the treatment of early breast cancer. Single photon emission computed tomography with computed tomography (SPECT/CT) has been commonly used for SN detection. SPECT/CT adds precise anatomical information of SN sites, and it is reported that more SNs may be detectable on SPECT/CT than on planar imaging. We here investigate which breast cancer patients have benefited from SPECT/CT over planar imaging. METHODS:A total of 273 breast cancer patients including 80 with ipsilateral breast tumor relapse (IBTR) underwent both multiple-view planar imaging and SPECT/CT for SN detection. The number of SNs, the patients who had benefitted from SPECT/CT, and the SN procedure failure rate were compared between SPECT/CT and planar imaging. Factors influencing the visualization of para-sternal and ipsilateral level II, III nodes, and contralateral axillary nodes were also analyzed using logistic regression analysis. RESULTS:The number of hot spots did not differ between SPECT/CT and multiple-view planar imaging. Eight contaminated patients and 52 patients with visualized extra-level I axillary nodes benefited from identifying precise anatomical sites. Even though radioactive nodes could be harvested in most (192/193) of the non-IBTR patients (7/8 in non-SN visible patients), no radioactive nodes could be found during surgery in 11 of 80 IBTR patients. Axillary surgery (dissection) increased the visualization of para-sternal and level II, III axillary nodes, and previous irradiation increased the visualization of contralateral axillary nodes. CONCLUSION:Multiple-view planar imaging was equivalent to SPECT/CT for depicting hot nodes for radio-guided SN detection in breast cancer. SPECT/CT was useful when precise anatomical information was necessary, especially regarding sentinel lymph nodes other than ipsilateral axilla. Logistic regression analysis revealed that axillary surgery (dissection) increased the visualization of para-sternal and level II, III axillary nodes, and the only relevant factor influencing visualization of contralateral axillary SNs was previous radiation to the breast.

journal_name

Ann Nucl Med

authors

Koizumi M,Koyama M

doi

10.1007/s12149-018-1319-z

subject

Has Abstract

pub_date

2019-03-01 00:00:00

pages

160-168

issue

3

eissn

0914-7187

issn

1864-6433

pii

10.1007/s12149-018-1319-z

journal_volume

33

pub_type

杂志文章
  • Oncologic significance of unexpected osseous foci on FDG-PET without correlative CT abnormalities.

    abstract:PURPOSE:Our purpose was to explore the clinical significance of unexpected osseous foci on 18F-FDG-PET without correlative CT abnormalities (FWCT) in patients referred for oncologic evaluation. The significance of FDG-avid foci without correlative CT abnormalities has been previously explored in tissues such as breast,...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/s12149-020-01572-6

    authors: Zamora E,Valdivia AY

    更新日期:2021-01-13 00:00:00

  • Tumor thrombus in the inferior vena cava from colon cancer detected by 18F-FDG-PET.

    abstract::We present a case of inferior vena cava (IVC) tumor thrombus detected by fluorine- 18 fluorodeoxyglucose positron emission tomography (18F-FDG-PET). A man underwent operations for the treatment of sigmoid colon cancer at the age of 63. Because tumor markers [carcinoembryonic antigen (CEA) and CA19-9] were increased at...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/s12149-007-0003-5

    authors: Kaida H,Ishibashi M,Kurata S,Uchida M,Hayabuchi N

    更新日期:2007-06-01 00:00:00

  • Brown adipose tissue demonstrating intense FDG uptake in a patient with mediastinal pheochromocytoma.

    abstract::We present an interesting case with a central mediastinal pheochromocytoma showing intense F-18 fluorodeoxyglucose (FDG) uptake in tumor and systemic brown adipose tissue (BAT) mimicking metastases. The findings of hypertension and high plasma catecholamine concentration suggested the presence of pheochromocytoma. Med...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/s12149-007-0096-x

    authors: Kuji I,Imabayashi E,Minagawa A,Matsuda H,Miyauchi T

    更新日期:2008-04-01 00:00:00

  • I-131 biokinetics of remnant normal thyroid tissue and residual thyroid cancer in patients with differentiated thyroid cancer: comparison between recombinant human TSH administration and thyroid hormone withdrawal.

    abstract:OBJECTIVE:The aim of this study was to assess I-131 biokinetics in thyroid cancer and remnant tissue in patients with differentiated thyroid cancer using whole-body scan (WBS) and SPECT images acquired after I-131 therapy. The influence of thyroid stimulating hormone (TSH) stimulation method on the kinetics was also ev...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/s12149-017-1188-x

    authors: Hong CM,Kim CY,Son SH,Jung JH,Lee CH,Jeong JH,Jeong SY,Lee SW,Lee J,Ahn BC

    更新日期:2017-10-01 00:00:00

  • Does lung perfusion scintigraphy continue to have a role in the clinical management of patients suspected of pulmonary embolism in the CT pulmonary angiography era?

    abstract:OBJECTIVE:Acute pulmonary embolism (PE) is a life-threatening disorder with high mortality. A prompt diagnosis and treatment is essential for reducing the mortality rate. The purpose of the study is to evaluate if lung perfusion scintigraphy (LPS) continues to have a role in the clinical management of patients suspecte...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/s12149-018-1295-3

    authors: Koukouraki SI,Hatzidakis AA,Mitrouska I,Stathaki MI,Perisinakis K

    更新日期:2018-12-01 00:00:00

  • The role of positron emission tomography using carbon-11 and fluorine-18 choline in tumors other than prostate cancer: a systematic review.

    abstract::To systematically review published data on the role of positron emission tomography (PET) or PET/computed tomography (PET/CT) using either Carbon-11 ((11)C) or Fluorine-18 ((18)F) choline tracer in tumors other than prostatic cancer. A comprehensive literature search of studies published in PubMed/MEDLINE and Embase d...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章,评审

    doi:10.1007/s12149-012-0602-7

    authors: Treglia G,Giovannini E,Di Franco D,Calcagni ML,Rufini V,Picchio M,Giordano A

    更新日期:2012-07-01 00:00:00

  • Regional cerebral blood flow in a patient with Nasu-Hakola disease.

    abstract::We report a functional neuroimaging study of a 43-year-old woman with Nasu-Hakola disease (NHD). Regional cerebral blood flow (rCBF) images were measured with technetium-99m ethyl cysteinate dimer single photon emission computed tomography (SPECT). rCBF was decreased in the bilateral frontal lobes and thalamus. This f...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/BF02984623

    authors: Takeshita T,Kaminaga T,Tatsumi T,Hatanaka Y,Furui S

    更新日期:2005-06-01 00:00:00

  • The reproducibility of deep-inspiration breath-hold (18)F-FDG PET/CT technique in diagnosing various cancers affected by respiratory motion.

    abstract:BACKGROUND:The deep-inspiration breath-hold PET/CT (DIBH PET/CT) technique improves the limitations of diagnosing a lesion located in an area influenced by respiratory motion that results in spatial misregistrations caused by respiration between PET and CT. However, its reproducibility with regard to calculating the ma...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/s12149-010-0352-3

    authors: Nagamachi S,Wakamatsu H,Kiyohara S,Fujita S,Futami S,Arita H,Tamura S,Kawai K

    更新日期:2010-04-01 00:00:00

  • Prediction of all-cause death using (11)C-hydroxyephedrine positron emission tomography in Japanese patients with left ventricular dysfunction.

    abstract:OBJECTIVES:The aim of this study was to determine whether (11)C-hydroxyephedrine ((11)C-HED) can predict adverse events including all-cause death in Japanese patients with left ventricular (LV) dysfunction. BACKGROUND:Although (11)C-HED PET has been used to assess cardiac sympathetic innervation in various disease con...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/s12149-016-1081-z

    authors: Fujita W,Matsunari I,Aoki H,Nekolla SG,Kajinami K

    更新日期:2016-08-01 00:00:00

  • Washout rates of Tc-99m tetrofosmin in asymmetric septal hypertrophy.

    abstract::The aim of this study was to evaluate the washout rate of Tc-99m tetrofosmin in asymmetric septal hypertrophy (ASH). As Tc-99m tetrofosmin accumulation and retention depend on sarcolemmal and/or mitochondrial function, the presence or absence of abnormalities in the washout rate of Tc-99m tetrofosmin could provide inf...

    journal_title:Annals of nuclear medicine

    pub_type: 临床试验,杂志文章

    doi:10.1007/BF02986332

    authors: Büyükdereli G,Kanadasi M,Kibar M

    更新日期:2005-02-01 00:00:00

  • Value of analyzing deep gray matter and occipital lobe perfusion to differentiate dementia with Lewy bodies from Alzheimer's disease.

    abstract:OBJECTIVE:Dementia with Lewy bodies (DLB) is generally characterized by a decrease in regional cerebral blood flow (rCBF) in the occipital lobe. However, not all patients with DLB have this feature. We explored characteristics of rCBF pattern changes to improve the identification of DLB, in addition to occipital hypope...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/s12149-008-0193-5

    authors: Shimizu S,Hanyu H,Hirao K,Sato T,Iwamoto T,Koizumi K

    更新日期:2008-12-01 00:00:00

  • Assessment of collimators in radium-223 imaging with channelized Hotelling observer: a simulation study.

    abstract:OBJECTIVE:Radium-223 (223Ra) is used in unsealed radionuclide therapy for metastatic bone tumors. The aim of this study is to apply a computational model observer to 223Ra planar images, and to assess the performance of collimators in 223Ra imaging. METHODS:The 223Ra planar images were created via an in-house Monte Ca...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/s12149-018-1286-4

    authors: Takahashi A,Baba S,Sasaki M

    更新日期:2018-12-01 00:00:00

  • Assessment of myocardial viability in patients with myocardial infarction using twenty-four hour thallium-201 late redistribution imaging.

    abstract:BACKGROUND:Rest thallium-201 (201Tl) myocardial perfusion imaging has been widely used for evaluation of myocardial ischemia/viability after myocardial infarction, but the ideal timing for imaging after injection to maximally estimate viability is not well established. METHODS:Thirty-six patients with myocardial infar...

    journal_title:Annals of nuclear medicine

    pub_type: 临床试验,杂志文章

    doi:10.1007/BF02985586

    authors: Yang XJ,He YM,Zhang B,Wu YW,Hui J,Jiang TB,Song JP,Liu ZH,Jiang WP

    更新日期:2006-01-01 00:00:00

  • Novel algorithm for quantitative assessment of left ventricular dyssynchrony with ECG-gated myocardial perfusion SPECT: useful technique for management of cardiac resynchronization therapy.

    abstract:OBJECTIVES:Cardiac resynchronization therapy (CRT) is the established treatment for patients with chronic and severe heart failure, and it has been reported that the presence of left ventricular (LV) dyssynchrony is one of the most important factors which predict positive response of this therapy. In the present study,...

    journal_title:Annals of nuclear medicine

    pub_type: 临床试验,杂志文章

    doi:10.1007/s12149-011-0525-8

    authors: Kiso K,Imoto A,Nishimura Y,Kanzaki H,Noda T,Kamakura S,Ishida Y

    更新日期:2011-12-01 00:00:00

  • Relationships among regional diastolic impairment, elongation of global time to peak filling rate, and global diastolic function using ECG-gated myocardial perfusion SPECT in heart failure.

    abstract:OBJECTIVE:The relationships among regional diastolic impairment, the elongation of global time to peak filling rate (g-TPF), and global diastolic function were examined by a novel program using electrocardiography-gated myocardial perfusion single-photon emission computed tomography (SPECT) (GMPS) in heart failure (HF)...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/s12149-007-0046-7

    authors: Yamamoto A,Takahashi N,Munakata K,Abe K,Kobayashi Y,Tamai J,Shiiba M,Okuyama T,Kaneshiro T,Tsuruta H,Takama T,Satou M

    更新日期:2007-10-01 00:00:00

  • Discontinuation of metformin to prevent metformin-induced high colonic FDG uptake: is 48 h sufficient?

    abstract:OBJECTIVE:In this retrospective, single-center observational study, we investigated whether discontinuing metformin for at least 48 h prevents metformin-induced [18F]fluorodeoxyglucose (FDG) uptake in all segments of the colon. METHODS:Patients with type 2 diabetes who were using metformin before undergoing an FDG PET...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/s12149-020-01509-z

    authors: Schreuder N,Klarenbeek H,Vendel BN,Jager PL,Kosterink JGW,van Puijenbroek EP

    更新日期:2020-11-01 00:00:00

  • Optimal ROI setting on the anatomically normalized I-123 FP-CIT images using high-resolution SPECT.

    abstract:OBJECTIVE:The aim of this study is to establish the optimal regions of interest (ROIs) in anatomically normalized I-123 FP-CIT SPECT images for the quantification of dopamine transporter binding. METHODS:The subjects comprised 16 normal controls and 14 Parkinsonian patients. All of the normal control subjects underwen...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/s12149-016-1107-6

    authors: Nonokuma M,Kuwabara Y,Hida K,Tani T,Takano K,Yoshimitsu K

    更新日期:2016-11-01 00:00:00

  • Left ventricular systolic/diastolic function evaluated by quantitative ECG-gated SPECT: comparison with echocardiography and plasma BNP analysis.

    abstract:OBJECTIVE:The aim of this study was to evaluate the left ventricular (LV) functional parameters calculated using quantitative electrocardiography (ECG)-gated myocardial perfusion single photon emission computed tomography (QGS). In addition to LV systolic parameters, diastolic parameters were compared with those by ult...

    journal_title:Annals of nuclear medicine

    pub_type: 临床试验,杂志文章

    doi:10.1007/BF02985571

    authors: Nakae I,Matsuo S,Koh T,Mitsunami K,Horie M

    更新日期:2005-09-01 00:00:00

  • A systematic review of the prognostic value of texture analysis in 18F-FDG PET in lung cancer.

    abstract:OBJECTIVE:The aim of this study was to perform a systematic review of the prognostic value of texture parameters derived by 18F-fluorodeoxyglucose positron emission tomography (18F-FDG PET) in patients with lung cancer. METHODS:PubMed and EMBASE databases were searched up to March 12, 2018, for original articles invol...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章,meta分析,评审

    doi:10.1007/s12149-018-1281-9

    authors: Han S,Woo S,Suh CH,Kim YJ,Oh JS,Lee JJ

    更新日期:2018-11-01 00:00:00

  • Causes of false negatives in technetium-99 m methoxyisobutylisonitrile scintigraphy for hyperparathyroidism: influence of size and cysts in parathyroid lesions.

    abstract:OBJECTIVE:The aim of this study was to elucidate the causes of false-negative cases of technetium-99 m methoxyisobutylisonitrile scintigraphy (MIBI) for hyperparathyroidism. METHODS:Consecutive MIBI examinations performed in 154 patients between April 2011 and March 2017 were retrospectively reviewed. Sensitivities of...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/s12149-020-01520-4

    authors: Ishii S,Sugawara S,Yaginuma Y,Kobiyama H,Hiruta M,Watanabe H,Yamakuni R,Hakozaki M,Fujimaki H,Ito H

    更新日期:2020-12-01 00:00:00

  • Impact of CT attenuation correction by SPECT/CT in brain perfusion images.

    abstract:PURPOSE:The aim of this study was to elucidate the regional differences between brain perfusion single photon emission computed tomography (SPECT) images reconstructed with a uniform attenuation correction using Chang's method (AC-Chang) and a non-uniform attenuation correction with CT using SPECT/CT (AC-CT). METHODS:...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/s12149-011-0567-y

    authors: Ishii K,Hanaoka K,Okada M,Kumano S,Komeya Y,Tsuchiya N,Hosono M,Murakami T

    更新日期:2012-04-01 00:00:00

  • A case of inferior vena cava thrombosis and pulmonary embolism secondary to acute exacerbation of chronic pancreatitis: a rare finding in radionuclide venography.

    abstract::A rare case of inferior vena cava (IVC) thrombosis and pulmonary embolism secondary to acute exacerbation of chronic pancreatitis was reported. Radionuclide venography and lung perfusion scintigraphy were performed on a 46-year-old male with acute exacerbation of chronic pancreatitis who complained of mild swelling of...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/BF02993720

    authors: Ohta H,Hachiya T

    更新日期:2002-04-01 00:00:00

  • Prognostic value of semi-quantitative tumor uptake on Tc-99m sestamibi breast-specific gamma imaging in invasive ductal breast cancer.

    abstract:OBJECTIVES:This study investigated the prognostic value of preoperative breast-specific gamma imaging (BSGI) uptake measured by a semi-quantitative method in invasive ductal carcinoma (IDC). METHODS:One hundred and sixty-two women with IDC who underwent preoperative BSGI were retrospectively enrolled. The tumor-to-nor...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/s12149-015-0977-3

    authors: Yoon HJ,Kim Y,Chang KT,Kim BS

    更新日期:2015-08-01 00:00:00

  • Differential diagnosis between (18)F-FDG-avid metastatic lymph nodes in non-small cell lung cancer and benign nodes on dual-time point PET/CT scan.

    abstract:OBJECTIVE:To clarify the difference of (18)F-FDG uptake kinetics between FDG-avid metastatic lymph nodes (LNs) in patients with non-small-cell lung cancer (NSCLC) and FDG-avid benign LNs associated with various etiologies on dual-time point PET/CT scan, and to determine the optimal parameter for differentiation. METHO...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/s12149-009-0268-y

    authors: Suga K,Kawakami Y,Hiyama A,Sugi K,Okabe K,Matsumoto T,Ueda K,Tanaka N,Matsunaga N

    更新日期:2009-08-01 00:00:00

  • Preparation of a fine powder of 2-deoxy-2-[18F]fluoro-D-glucose suitable for inhalation to diagnose lung diseases by means of PET.

    abstract::Fine 2-deoxy-2-[18F]fluoro-D-glucose (18FDG) powder was obtained by adding diethyl ether into a methyl alcohol solution of 18FDG and other sugar as seed. When micronized particles of sodium N-acetyl-neuraminate (Neu5Ac-Na) were used as seed crystals, particles containing 18FDG were obtained and 80% of them were smalle...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/BF03178301

    authors: Ojima F,Ido T,Takahashi T,Hatazawa J,Ito M,Sasaki H,Yanai M,Aikawa T,Takishima T,Abiko K

    更新日期:1989-11-01 00:00:00

  • Correction of scattered photons in Tc-99m imaging by means of a photopeak dual-energy window acquisition.

    abstract::We are proposing a new method for correcting of scattered photons in technetium-99m (99mTc) imaging by means of photopeak dual-energy window acquisition. This method consists of the simultaneous acquisition of two images and estimation of a scatter image included in the symmetric energy window (SW) image by the differ...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/BF03178307

    authors: Kojima A,Tsuji A,Takaki Y,Tomiguchi S,Hara M,Matsumoto M,Takahashi M

    更新日期:1992-08-01 00:00:00

  • Equal sensitivity of early and late scans after injection of FDG for the detection of Alzheimer pattern: an analysis of 3D PET data from J-ADNI, a multi-center study.

    abstract:OBJECTIVE:To determine the optimal accumulation time for three-dimensional positron emission tomography (3D-PET) with (18)F-2-fluoro-2-deoxy-D-glucose ((18)F-FDG) to detect the brain uptake pattern typical of Alzheimer's disease (AD). METHODS:Patients with mild AD or amnestic mild cognitive impairment (MCI) and normal...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s12149-013-0704-x

    authors: Takahashi R,Ishii K,Senda M,Ito K,Ishii K,Kato T,Makishi Y,Nishio T,Ikari Y,Iwatsubo T,Japanese Alzheimer’s Disease Neuroimaging Initiative.

    更新日期:2013-06-01 00:00:00

  • Extrarenal uptake of Tc-99m-DTPA in a case of retroperitoneal abscess causing spurious data in renal function assessment.

    abstract::The author reports CT of the abdomen and quantitative analysis of renal scintigraphy that was spuriously assessed due to unwanted extrarenal uptake. The patient had a retroperitoneal abscess that was related to fistula from the right kidney. Renal scintigraphy was performed to assess split renal function as a preopera...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/BF03164784

    authors: Choe W

    更新日期:1998-06-01 00:00:00

  • Development of a simple non-invasive microsphere quantification method for cerebral blood flow using I-123-IMP.

    abstract:OBJECTIVE:In clinical practice, measurement of the rCBF has mainly been conducted by I-123-N-isopropyl-p-iodoamphetamine ((123)I-IMP) SPECT using the microsphere (MS) method, with continuous arterial blood sampling. While several non-invasive (123)I-IMP quantification methods have been developed, their accuracy has bee...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/s12149-015-1053-8

    authors: Ofuji A,Mimura H,Yamashita K,Takaki A,Sone T,Ito S

    更新日期:2016-04-01 00:00:00

  • Preserved benzodiazepine receptors in Alzheimer's disease measured with C-11 flumazenil PET and I-123 iomazenil SPECT in comparison with CBF.

    abstract::This study evaluates the regional cerebral blood flow (CBF) with H2(15)O-PET and the distribution of central benzodiazepine receptor (BZR) with C-11 flumazenil (FMZ) by PET and I-123 iomazenil (IMZ) by SPECT in Alzheimer's disease (AD). In AD, whereas the CBF was diminished in the frontal, temporal, parietal, and occi...

    journal_title:Annals of nuclear medicine

    pub_type: 杂志文章

    doi:10.1007/BF03164869

    authors: Ohyama M,Senda M,Ishiwata K,Kitamura S,Mishina M,Ishii K,Toyama H,Oda K,Katayama Y

    更新日期:1999-10-01 00:00:00