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Aortic knob width reflects left ventricular diastolic function assessed by gated myocardial perfusion single photon emission computed tomography in patients with normal myocardial perfusion.

Abstract：

BACKGROUND:Aortic knob width on chest radiography represents the extent of aortic dialation and tortuosity of the aortic arch. We tested the hypothesis that aortic knob width reflected left ventricular (LV) diastolic function assessed by gated myocardial perfusion single photon emission computed tomography (SPECT) in patients with normal myocardial perfusion. METHODS:One hundred and thirty patients with preserved LV ejection fraction and normal myocardial perfusion were enrolled in this study. Aortic knob width was measured along the horizontal line from the point of the lateral edge of the trachea to the left lateral wall of the aortic knob. The peak filling rate (PFR) and the one-third mean filling rate (1/3 MFR) were obtained as LV diastolic parameters. RESULTS:There were 114 male and 16 female patients. Age ranged from 43 to 88 years (69.9 ± 8.9 years). Aortic knob width ranged from 24.2 to 53.4 mm (37.6 ± 5.7 mm). There was a significant correlation between age and aortic knob width (r = 0.34, p < 0.001). Aortic knob width was inversely correlated with both PFR (r = -0.53, p < 0.001) and 1/3 MFR (r = -0.42, p < 0.001). Multivariate linear regression analysis revealed that serum creatinine (β = -0.16, p = 0.045) and aortic knob width (β = -0.45, p < 0.001) were significant predictors of PFR, and that age (β = -0.20, p = 0.02) and aortic knob width (β = -0.33, p < 0.001) were significant predictors of 1/3 MFR. CONCLUSIONS:Our data suggested that aortic knob width on chest radiography was a simple marker of LV diastolic function in patients with normal myocardial perfusion.

journal_name

Ann Nucl Med

journal_title

Annals of nuclear medicine

authors

Kurisu S,Higaki T,Sumimoto Y,Ikenaga H,Watanabe N,Ishibashi K,Dohi Y,Fukuda Y,Kihara Y

doi

10.1007/s12149-017-1150-y

subject

Has Abstract

pub_date

2017-04-01 00:00:00

pages

245-249

issue

eissn

0914-7187

issn

1864-6433

pii

10.1007/s12149-017-1150-y

journal_volume

pub_type

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Aortic knob width reflects left ventricular diastolic function assessed by gated myocardial perfusion single photon emission computed tomography in patients with normal myocardial perfusion.