Pet tracers for vulnerable plaque imaging.

abstract：:Scintigraphy with 99mTc-diethylenetriamine pentaacetic acid galactosyl human serum albumin (99mTc-GSA) was performed on 102 patients, then the hepatic extraction fraction (HEF), the rate constant for liver uptake of the tracer from the blood (K1) and the hepatic blood flow index (HBFI) were determined by spectral anal...

journal_title：Annals of nuclear medicine

authors： Fukui A,Murase K,Tsuda T,Fujii T,Ikezoe J

更新日期：2000-12-01 00:00:00

abstract：OBJECTIVE:In the initial assessment of thyroid nodules, thyrotropin (TSH) has very low sensitivity for assessing functional thyroid nodules (FTNs). The false negativity in FTNs and the false positivity in non-FTNs misinterpreted by TSH will raise unnecessary assessment costs. Therefore, the aim of this study is to expl...

journal_title：Annals of nuclear medicine

authors： Cai H,Qiao Y,Huang X,Sun M,Luo Q,Yuan X,Yang Y,Mao W,Lv Z

更新日期：2017-01-01 00:00:00

abstract：:67Ga-citrate and 99mTc(V)-DMSA images were obtained in a patient with recurrent extraabdominal fibromatosis of the left calf. The 67Ga-citrate image showed abnormal uptake in the left calf lesion and right calf, which was considered due to probable myositis caused by overexertion. On the other hand, the 99mTc(V)-DMSA ...

journal_title：Annals of nuclear medicine

authors： Ohta H,Komibuchi T,Tomihara M,Watanabe H,Fujikawa S,Shintaku M

更新日期：1998-08-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to investigate if increased serum thyroglobulin (Tg) levels after radioactive iodine (RAI) showed more therapeutic effects in patients with differentiated thyroid cancer (DTC). METHODS:Data of 65 patients with DTC who underwent RAI from June 2014 to September 2016 were reviewed. Ser...

journal_title：Annals of nuclear medicine

authors： Choi JH,Lim I,Lee I,Byun BH,Kim BI,Choi CW,Lim SM

更新日期：2019-02-01 00:00:00

abstract：OBJECTIVE:To evaluate the usefulness of a breath-holding (BH) (18)F-2-fluoro-2-deoxy-D-glucose positron emission tomography ((18)F-FDG-PET) technique for PET/computed tomography (CT) scanning of pulmonary lesions near the diaphragm, where image quality is influenced by respiratory motion. METHODS:In a basic study, sim...

journal_title：Annals of nuclear medicine

authors： Yamaguchi T,Ueda O,Hara H,Sakai H,Kida T,Suzuki K,Adachi S,Ishii K

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVE:The objective of this study is to assess the value of CT and bone scintigraphic findings for grading of rib chondrosarcoma. METHODS:Included in this study were six cases of histologically proven chondrosarcoma of the rib, in which bone scintigraphy and/or CT was performed. Correlation of histologic grade (I-...

journal_title：Annals of nuclear medicine

authors： Ehara S,Nakayama T,Nishida J,Shiraishi H,Yoshioka H,Aoki J

更新日期：2004-10-01 00:00:00

abstract：:Bacterial orbital cellulitis is an infection of the soft tissues behind the orbital septum. Cellulitis is seen as a poorly defined area of increased CT density or T2 signal intensity within the fat. There is an amorphous enhancement following contrast infusion. Radiolabeled leukocytes or granulocytes are now establish...

journal_title：Annals of nuclear medicine

authors： Sayit E,Söylev M,Capa G,Durak I,Ada E,Yilmaz M,Durak H

更新日期：2001-02-01 00:00:00

abstract：PURPOSE:The objectives of this study were to (1) elucidate the relationship between the mean CBF in the whole brain (Av.mCBF) before rehabilitation of CVD patients and the BI score before and after rehabilitation, (2) determine whether the efficacy of rehabilitation can be predicted by measurement of the Av.mCBF, and (...

journal_title：Annals of nuclear medicine

authors： Tamamoto F,Sumi Y,Nakanishi A,Okayasu K,Maehara T,Katayama H

更新日期：2000-02-01 00:00:00

abstract：OBJECTIVE:Among different PET tracers, 18F-fludeoxyglucose (FDG) and 11C-choline are known to have a high tumor uptake correlated with a high mitotic index of tumor cells. Thus, the uptake of 18F-FDG and 11C-choline may be dependent on the cell cycle. In the present study, we examined the uptake of 18F-FDG and 11C-chol...

journal_title：Annals of nuclear medicine

authors： Roppongi M,Izumisawa M,Terasaki K,Muraki Y,Shozushima M

更新日期：2019-04-01 00:00:00

abstract：:A method has been described to optimize the cutoff frequency of the Butterworth filter for brain SPECT imaging. Since a computer simulation study has demonstrated that separation between an object signal and the random noise in projection images in a spatial-frequency domain is influenced by the total number of counts...

journal_title：Annals of nuclear medicine

authors： Minoshima S,Maruno H,Yui N,Togawa T,Kinoshita F,Kubota M,Berger KL,Uchida Y,Uno K,Arimizu N

更新日期：1993-05-01 00:00:00

abstract：OBJECTIVE:Accurate and validated methods for estimating regional PET image noise are helpful for optimizing image processing. The bootstrap is a data-based simulation method for statistical inference, which can be used to estimate the PET image noise without repeated measurements. The aim of this study was to experimen...

journal_title：Annals of nuclear medicine

authors： Ibaraki M,Matsubara K,Nakamura K,Yamaguchi H,Kinoshita T

更新日期：2014-02-01 00:00:00

abstract：OBJECTIVE:We investigated the changes in 125I-iomazenil (125I-IMZ) benzodiazepine receptor (BZR) binding with psychological stress in a rat model. METHODS:Six male Wistar rats were placed under psychological stress for 1 hour by using a communication box. No physical stress was not received. 1.85 MBq of 125I-IMZ was i...

journal_title：Annals of nuclear medicine

authors： Fukumitsu N,Tsuchida D,Ogi S,Uchiyama M,Mori Y

更新日期：2002-05-01 00:00:00

abstract：OBJECTIVE:Because thickening of the gallbladder wall is observed not only in patients with gallbladder cancer but also in those with benign diseases such as chronic cholecystitis and gallbladder adenomyosis, it is difficult to distinguish between benign and malignant gallbladder wall thickening by conventional techniqu...

journal_title：Annals of nuclear medicine

authors： Oe A,Kawabe J,Torii K,Kawamura E,Higashiyama S,Kotani J,Hayashi T,Kurooka H,Tsumoto C,Kubo S,Shiomi S

更新日期：2006-12-01 00:00:00

abstract：:Scintigraphy with 99mTc-diethylenetriaminepentaacetate with galactosyl human serum albumin (99mTc-GSA) and per-rectal portal scintigraphy are useful for evaluating hepatic functional reserve and portal circulation, respectively. We did the procedures simultaneously in some patients to examine the relationship between ...

journal_title：Annals of nuclear medicine

authors： Shiomi S,Iwata Y,Sasaki N,Kurooka H,Tamori A,Habu D,Takeda T,Nishiguchi S,Kuroki T,Ochi H

更新日期：1999-08-01 00:00:00

abstract：OBJECTIVE:4-Benzyl-1-(3-iodobenzylsulfonyl)piperidine, 4-B-IBSP, has shown high-binding affinity to both sigma (σ) receptors in our previous work. In current study, radiolabeling and preclinical evaluation of 4-benzyl-1-(3-[125I]-iodobenzylsulfonyl)piperidine, 4-B-[125I]IBSP, in human ductal breast carcinoma (T47D) cel...

journal_title：Annals of nuclear medicine

authors： Sadeghzadeh M,Alirezapour B,Charkhlooie GA,Baghery MK,Khorouti A

更新日期：2017-05-01 00:00:00

abstract：OBJECTIVE:To assess the role of serial FLT-PET scans during early neoadjuvant treatment as a prognostic marker of response to treatment and survival. METHODS:This study is a prospective cohort study which draws from a larger original study which examined the utility of FLT-PET imaging across multiple cancers. Our coho...

journal_title：Annals of nuclear medicine

authors： Ueberroth BE,Lawhorn-Crews JM,Heilbrun LK,Smith DW,Akoury J,Ali-Fehmi R,Eiseler NT,Shields AF

更新日期：2019-06-01 00:00:00

abstract：AIM:The purpose of the study was to determine the lung toxicity caused by amiodarone (AD) and bleomycin (BLM) in rats, by means of Tc-99m HMPAO lung scintigraphy. METHODS:Thirty albino rats were randomly divided into five groups. After AD or BLM was dissolved with isotonic saline (SF), a 0.5 ml solution was applied to...

journal_title：Annals of nuclear medicine

authors： Gumuser G,Vural K,Varol T,Parlak Y,Tuglu I,Topal G,Sayit E

更新日期：2013-08-01 00:00:00

abstract：OBJECTIVE:The Response Evaluation Criteria In Solid Tumors (RECIST) is the most used radiological method for evaluating response after peptide receptor radionuclide therapy (PRRT) in patients with neuroendocrine tumors. This method may give too positive estimates of response in slow growing tumors as it allows a substa...

journal_title：Annals of nuclear medicine

authors： Løitegård T,Berntzen DT,Thiis-Evensen E

更新日期：2019-03-01 00:00:00

abstract：UNLABELLED:We propose a new method to quantify regional myocardial blood flow (rMBF) by continuous infusion of Tc-99m MIBI and dynamic SPECT. METHODS:Five patients with old myocardial infarction were studied. During continuous infusion of MIBI (approximately 740 MBq) with a syringe pump in 10 min, dynamic SPECT scan w...

journal_title：Annals of nuclear medicine

authors： Tsuchida T,Yonekura Y,Takahashi N,Nakano A,Lee JD,Sadato N,Yamamoto K,Waki A,Sugimoto K,Hayashi N,Ishii Y

更新日期：1999-02-01 00:00:00

abstract：OBJECTIVE:To determine the optimal accumulation time for three-dimensional positron emission tomography (3D-PET) with (18)F-2-fluoro-2-deoxy-D-glucose ((18)F-FDG) to detect the brain uptake pattern typical of Alzheimer's disease (AD). METHODS:Patients with mild AD or amnestic mild cognitive impairment (MCI) and normal...

journal_title：Annals of nuclear medicine

authors： Takahashi R,Ishii K,Senda M,Ito K,Ishii K,Kato T,Makishi Y,Nishio T,Ikari Y,Iwatsubo T,Japanese Alzheimer’s Disease Neuroimaging Initiative.

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVE:We performed 67Gallium (Ga) single-photon emission computed tomography (SPECT) with integrated low-dose computed tomography (CT) for the interpretation of myocardial outline to investigate the value of co-registered fusion imaging using a hybrid system (SPECT/CT) in patients with cardiac sarcoidosis. METHODS...

journal_title：Annals of nuclear medicine

authors： Momose M,Kadoya M,Koshikawa M,Matsushita T,Yamada A

更新日期：2007-12-01 00:00:00

abstract：:We studied the cerebral muscarinic acetylcholinergic receptor (mACh-R) by means of 11C-N-methyl-4-piperidyl benzilate (11C-NMPB) and positron emission tomography (PET) in Alzheimer's disease (AD) cases, and the findings were compared with the cerebral blood flow (CBF) and the glucose metabolism (CMRGlc) to evaluate th...

journal_title：Annals of nuclear medicine

authors： Yoshida T,Kuwabara Y,Ichiya Y,Sasaki M,Fukumura T,Ichimiya A,Takita M,Ogomori K,Masuda K

更新日期：1998-02-01 00:00:00

abstract：OBJECTIVE:Studies have suggested that ischemia-induced diastolic dysfunction persists longer than systolic dysfunction. We examined whether global left ventricular (LV) diastolic function during stress testing assessed by 16-frame gated myocardial perfusion single-photon emission computed tomography (SPECT) is useful a...

journal_title：Annals of nuclear medicine

authors： Nakae I,Matsuo S,Matsumoto T,Mitsunami K,Horie M

更新日期：2008-10-01 00:00:00

abstract：PURPOSE:The purpose of this study was to evaluate whether the degree of technetium-99m methoxyisobutylisonitrile (MIBI) uptake and its retention in delayed imaging in small cell lung cancer (SCLC) was correlated with the response to multiagent chemotherapy and to investigate if there was a relationship between the surv...

journal_title：Annals of nuclear medicine

authors： Akgun A,Cok G,Karapolat I,Goksel T,Burak Z

更新日期：2006-05-01 00:00:00

abstract：:Positron emission tomography (PET) imaging is in common use preoperatively to clinically evaluate patients who present with central nervous system mass lesions. The usefulness of PET is also recognized as a method to detect intracranial tumorous lesions. A number of papers reportthat some inflammatory processes also s...

journal_title：Annals of nuclear medicine

authors： Tsuyuguchi N,Sunada I,Ohata K,Takami T,Nishio A,Hara M,Kawabe J,Okamura T,Ochi H

更新日期：2003-02-01 00:00:00

abstract：OBJECTIVE:Epidermal growth factor receptor tyrosine kinase (EGFR-TK) represents an attractive target for tumor diagnosis agents. Previously, the radioiodinated 4-(3-iodoanilino)-6,7-diethoxyquinazoline ([(125)I]m-IPQ) has been reported to possess good characteristics as a tumor imaging agent; however, it was also found...

journal_title：Annals of nuclear medicine

authors： Hirata M,Kanai Y,Naka S,Matsumuro K,Kagawa S,Yoshimoto M,Ohmomo Y

更新日期：2012-06-01 00:00:00

abstract：OBJECTIVE:In clinical practice, measurement of the rCBF has mainly been conducted by I-123-N-isopropyl-p-iodoamphetamine ((123)I-IMP) SPECT using the microsphere (MS) method, with continuous arterial blood sampling. While several non-invasive (123)I-IMP quantification methods have been developed, their accuracy has bee...

journal_title：Annals of nuclear medicine

authors： Ofuji A,Mimura H,Yamashita K,Takaki A,Sone T,Ito S

更新日期：2016-04-01 00:00:00

abstract：:We report scan findings of Tl-201 in a case of histologically proved Warthin's tumor. Dual isotopes acquisition was performed in a case of left parotid Warthin's tumor. Both early and delayed Tc-99m-pertechnetate (Tc-99m) images showed increased uptake at the tumor. Tl-201 scan also showed an increase of uptake on the...

journal_title：Annals of nuclear medicine

authors： Arbab AS,Koizumi K,Arai T,Toyama K,Araki T

更新日期：1996-08-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to investigate the effects of computed tomography (CT) artifacts caused by dental metal prostheses on positron emission tomography (PET) images. METHODS:A dental arch cast was fixed in a cylindrical water-bath phantom. A spherical phantom positioned in the vicinity of the dent...

journal_title：Annals of nuclear medicine

authors： Shimamoto H,Kakimoto N,Fujino K,Hamada S,Shimosegawa E,Murakami S,Furukawa S,Hatazawa J

更新日期：2009-07-01 00:00:00

abstract：OBJECTIVE:In this study, the feasibility and kinetic characteristics of the (68)Ga-NOTA-RGD, a recently developed RGD peptide agent, were investigated for atherosclerosis imaging in comparison with (18)FDG. METHODS:ApoE(-/-) mice were fed a high-fat diet for more than 20 weeks. To evaluate the feasibility, tissue upta...

journal_title：Annals of nuclear medicine

authors： Paeng JC,Lee YS,Lee JS,Jeong JM,Kim KB,Chung JK,Lee DS

更新日期：2013-11-01 00:00:00