解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::To date there are thirteen species validly assigned to the genus Anaerococcus. Most of the species in this genus are anaerobic and of human origin. Anaerococcus urinimassiliensis sp. nov., strain Marseille-P2143T is member of family Peptoniphilaceae, which was isolated from the urine of a 17-year-old boy affected by a...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-021-82420-z
更新日期:2021-01-29 00:00:00
abstract::HIV-1 latency generates reservoirs that prevent viral eradication by the current therapies. To find strategies toward an HIV cure, detailed understandings of the molecular mechanisms underlying establishment and persistence of the reservoirs are needed. The cellular transcription factor KAP1 is known as a potent repre...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-021-82164-w
更新日期:2021-01-29 00:00:00
abstract::The aim of this study is to compare patients with and without mastalgia and to analyze the factors affecting mastalgia and its severity. The patient's age, height, weight, educational status, marital status, and occupation were recorded in all subjects. In addition, the women were asked about the presence of any risk ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-021-82099-2
更新日期:2021-01-29 00:00:00
abstract::Oceanic physics at fine scale; e.g. eddies, fronts, filaments; are notoriously difficult to sample. However, an increasing number of theoretical approaches hypothesize that these processes affect phytoplankton diversity which have cascading effects on regional ecosystems. In 2015, we targeted the Iroise Sea (France) a...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-021-82071-0
更新日期:2021-01-29 00:00:00
abstract::Stochastic differential equations (SDEs) are ubiquitous across disciplines, and uncovering SDEs driving observed time series data is a key scientific challenge. Most previous work on this topic has relied on restrictive assumptions, undermining the generality of these approaches. We present a novel technique to uncove...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-021-81162-2
更新日期:2021-01-29 00:00:00
abstract::Saliva has immense potential as a diagnostic fluid for identification and monitoring of several systemic diseases. Composition of the microbiome and inflammation has been associated and reflective of oral and overall health. In addition, the relative ease of collection of saliva further strengthens large-scale diagnos...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-021-81420-3
更新日期:2021-01-29 00:00:00
abstract::The present study investigates the impact of charge variants on bevacizumab's structure, stability, and biological activity. Five basic and one acidic charge variants were separated using semi-preparative cation exchange chromatography using linear pH gradient elution with purity > 85%. Based on the commercial biosimi...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-79541-2
更新日期:2021-01-29 00:00:00
abstract::In eye movement perimetry (EMP), the saccadic reaction time (SRT) to 'seen' visual stimuli are delayed in glaucoma. Evaluating SRT behaviour in hemi-field sectors could refine its clinical implication. The development phase included 60 controls retrospectively and for the test cohort in evaluation phase, another 30 he...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-021-81762-y
更新日期:2021-01-29 00:00:00
abstract::The first instar larva of a species of the Australian endemic genus Aenigmetopia Malloch is described for the first time, along with the first instar larvae of three other Australian species representing the genera Amobia Robineau-Desvoidy and Protomiltogramma Townsend. Larval morphology was analysed using a combinati...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-80139-x
更新日期:2021-01-29 00:00:00
abstract::Bioavailability of α-tocopherol varies with source, dose and duration of supplementation. The effect of source and dose of α-tocopherol on response of α-tocopherol stereoisomers in plasma and tissues of mink kits during the weaning period was studied. Twelve mink kits were euthanised in CO2 at the beginning of the exp...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-80902-0
更新日期:2021-01-29 00:00:00
abstract::Three-dimensional ion and particle concentrations under hydrodynamic focusing in a Y-shaped square microchannel are numerically simulated to clarify the decrease of the ion concentration along the flow direction within the focused particle stream. The simulation model is theoretically governed by the laminar flow and ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-021-82259-4
更新日期:2021-01-28 00:00:00
abstract::To provide a comprehensive analysis of small molecule genotoxic potential we have developed and validated an automated, high-content, high throughput, image-based in vitro Micronucleus (IVM) assay. This assay simultaneously assesses micronuclei and multiple additional cellular markers associated with genotoxicity. Aco...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-021-82115-5
更新日期:2021-01-28 00:00:00
abstract::Neutrophil gelatinase-associated lipocalin (NGAL) is involved in cardiovascular and renal diseases. Gene inactivation of NGAL blunts the pathophysiological consequences of cardiovascular and renal damage. We aimed to design chemical NGAL inhibitors and investigate its effects in experimental models of myocardial infar...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-021-82279-0
更新日期:2021-01-28 00:00:00
abstract::We report an experimental demonstration of positive-negative sub-wavelength interference without correlation. Typically, people can achieve sub-wavelength effects with correlation measurement no matter by using bi-photon or thermal light sources. In this paper, we adopt a thermal light source, and we count the realiza...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-021-82030-9
更新日期:2021-01-28 00:00:00
abstract::The identification of genome-wide selection signatures can provide insights on the mechanisms of natural and/or artificial selection and uncover genes related to biological functions and/or phenotypes. Tibetan sheep are an important livestock in Tibet, providing meat and wool for Tibetans who are renown for breeding l...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-021-81932-y
更新日期:2021-01-28 00:00:00
abstract::Cutaneous allodynia (CA) is a pain in response to non-nociceptive stimulation and a marker of central sensitisation. Probable migraine (PM) is a migraine subtype that fulfils all but one criterion of migraine. Headache intensity and the disability of individuals with PM are similar or lower than individuals with migra...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-021-82080-z
更新日期:2021-01-28 00:00:00
abstract::Neuroticism is a personality trait, which is an important risk factor for psychiatric disorders. Recent genome-wide studies reported about 600 genes potentially influencing neuroticism. Little is known about the mechanisms of their action. Here, we aimed to conduct a more detailed analysis of genes that can regulate t...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-021-82123-5
更新日期:2021-01-28 00:00:00
abstract::Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection is currently a global pandemic, and there are limited laboratory studies targeting pathogen resistance. This study aimed to investigate the effect of selected disinfection products and methods on the inactivation of SARS-CoV-2 in the laboratory. We...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-021-82148-w
更新日期:2021-01-28 00:00:00
abstract::Nonstoichiometric silicon nitride SiNx is a promising material for developing a new generation of high-speed, reliable flash memory device based on the resistive effect. The advantage of silicon nitride over other dielectrics is its compatibility with the silicon technology. In the present work, a silicon nitride-base...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-021-82159-7
更新日期:2021-01-28 00:00:00
abstract::The capacity of marine organisms to adapt and/or acclimate to climate change might differ among distinct populations, depending on their local environmental history and phenotypic plasticity. Kelp forests create some of the most productive habitats in the world, but globally, many populations have been negatively impa...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-021-82094-7
更新日期:2021-01-28 00:00:00
abstract::Terahertz (THz) technology has emerged recently as a potential novel imaging modality in biomedical fields, including ophthalmology. However, the ocular biological responses after THz electromagnetic exposure have not been investigated. We conducted a rabbit study to evaluate the safety profiles of THz scanning on eye...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-021-82103-9
更新日期:2021-01-28 00:00:00
abstract::New Delhi metallo-β-lactamase (NDM) had been reported to be the predominant carbapenemase among Escherichia coli in Taiwan. However, studies focusing on the clonal background and epidemiology of plasmids carrying NDM genes were limited. Between 2016 and 2018, all clinical E. coli and Klebsiella pneumoniae isolates tha...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-021-82166-8
更新日期:2021-01-28 00:00:00
abstract::The rapid spread of the SARS-CoV-2 in the COVID-19 pandemic had raised questions on the route of transmission of this disease. Initial understanding was that transmission originated from respiratory droplets from an infected host to a susceptible host. However, indirect contact transmission of viable virus by fomites ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-021-81935-9
更新日期:2021-01-28 00:00:00
abstract::Amazonian wildfires in 2019 have raised awareness about rainforest burning due to increased emissions of particulate matter and carbon. In the context of these emissions, by-products of lignin thermal degradation (i.e. methoxyphenols) are often neglected. Methoxyphenols entering the atmosphere may form intermediates w...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-021-81789-1
更新日期:2021-01-28 00:00:00
abstract::Biological computation requires in vivo control of molecular behavior to progress development of autonomous devices. miRNA switches represent excellent, easily engineerable synthetic biology tools to achieve user-defined gene regulation. Here we present the construction of a synthetic network to implement detoxificati...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-021-81679-6
更新日期:2021-01-28 00:00:00
abstract::Earliness per se (Eps) genes are reported to be important in fine-tuning flowering time in wheat independently of photoperiod (Ppd) and vernalisation (Vrn). Unlike Ppd and Vrn genes, Eps have relatively small effects and their physiological effect along with chromosomal position are not well defined. We evaluated eigh...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-021-81857-6
更新日期:2021-01-28 00:00:00
abstract::The interlocking roles of lexical, syntactic and semantic processing in language comprehension has been the subject of longstanding debate. Recently, the cortical response to a frequency-tagged linguistic stimulus has been shown to track the rate of phrase and sentence, as well as syllable, presentation. This could be...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-021-81901-5
更新日期:2021-01-28 00:00:00
abstract::Laparoscopic cholecystectomy (LC) is the standard technique for treatment of gallbladder disease. In case of acute cholecystitis we can identify preoperative factors associated with an increased risk of conversion and intraoperative complications. The aim of our study was to detect preoperative laboratory and radiolog...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-021-81938-6
更新日期:2021-01-28 00:00:00
abstract::Aggregates of corundum crystals with skeletal to hopper morphology occur in pyroclastic rocks erupted from Cretaceous basaltic volcanoes on Mt Carmel, N. Israel. The rapid growth of the crystals trapped volumes of the parental Al2O3-supersaturated melt; phenocrysts of tistarite (Ti2O3) in the trapped melts indicate cr...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-79739-4
更新日期:2021-01-28 00:00:00
abstract::Nitrous-oxide emission and nitrate addition from agriculture to earth's environment are two main agriculture related anthropogenic causes of environmental degradation that needs greater attention. For addressing the aforesaid issue, new techniques/practices need to be developed and implemented. The present investigati...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-021-81739-x
更新日期:2021-01-28 00:00:00
abstract::Despite the frequent use of ionising radiation (IR) in therapy and diagnostics and the unavoidable exposure to external radiation sources, our knowledge regarding the radiosensitivity of human blood cell populations is limited and published data, obtained under different experimental conditions, are heterogeneous. To ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-021-81058-1
更新日期:2021-01-28 00:00:00
abstract::This study aimed to compare the accuracy of novel lipid indices, including the visceral adiposity index (VAI), lipid accumulation product (LAP), triglycerides and glucose (TyG) index, TyG-body mass index (TyG-BMI), and TyG-waist circumference (TyG-WC), in identifying insulin resistance and establish valid cutoff value...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-021-82053-2
更新日期:2021-01-27 00:00:00
abstract::To report the efficacy and safety of large diameter scleral lenses and determine their suitability in Asian subjects with intractable ocular surface diseases. This prospective study enrolled intractable ocular surface diseases subjects with uncorrected visual acuity > counting finger but ≥ 0.3 logMAR and best-correcte...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-021-82010-z
更新日期:2021-01-27 00:00:00
abstract::We study a minimal model of the stress-driven p53 regulatory network that includes competition between active and mutant forms of the tumor-suppressor gene p53. Depending on the nature and level of the external stress signal, four distinct dynamical states of p53 are observed. These states can be distinguished by diff...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-021-82054-1
更新日期:2021-01-27 00:00:00
abstract::Biofilms are complex microbial communities that present serious contamination risks to our environment and health. In this study, atmospheric air plasma and airborne acoustic ultrasound technology were applied to inactivate Escherichia coli and Listeria innocua biofilms. Both technologies were efficient in controlling...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-021-81977-z
更新日期:2021-01-27 00:00:00
abstract::The exponential growth in knowledge has resulted in a better understanding of the lactation process in a wide variety of animals. However, the underlying genetic mechanisms are not yet clearly known. In order to identify the mechanisms involved in the lactation process, various mehods, including meta-analysis, weighte...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-021-81888-z
更新日期:2021-01-27 00:00:00
abstract::G-proteins are implicated in plant productivity, but their genome-wide roles in regulating agronomically important traits remain uncharacterized. Transcriptomic analyses of rice G-protein alpha subunit mutant (rga1) revealed 2270 differentially expressed genes (DEGs) including those involved in C/N and lipid metabolis...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-021-81824-1
更新日期:2021-01-27 00:00:00
abstract::It well-known that mental training improves skill performance. Here, we evaluated skill acquisition and consolidation after physical or motor imagery practice, by means of an arm pointing task requiring speed-accuracy trade-off. In the main experiment, we showed a significant enhancement of skill after both practices ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-021-81994-y
更新日期:2021-01-27 00:00:00
abstract::Many studies speak in favor of a rhythmic mode of listening, by which the encoding of acoustic information is structured by rhythmic neural processes at the time scale of about 1 to 4 Hz. Indeed, psychophysical data suggest that humans sample acoustic information in extended soundscapes not uniformly, but weigh the ev...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-021-82008-7
更新日期:2021-01-27 00:00:00
abstract::The heterogeneity of major depressive disorder (MDD) is attributed to the fact that diagnostic criteria (e.g., DSM-5) are only based on clinical symptoms. The discovery of blood biomarkers has the potential to change the diagnosis of MDD. The purpose of this study was to identify blood biomarkers of DNA methylation by...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-021-81758-8
更新日期:2021-01-27 00:00:00