Abstract：
:Biofilms are complex microbial communities that present serious contamination risks to our environment and health. In this study, atmospheric air plasma and airborne acoustic ultrasound technology were applied to inactivate Escherichia coli and Listeria innocua biofilms. Both technologies were efficient in controlling, or completely inactivating, the target bacterial biofilms. Viability and metabolic assays, along with microscopy analysis, revealed that atmospheric air plasma and airborne acoustic ultrasound damaged both the bacterial biofilm cells and its structural integrity. Scanning electron microscopy images highlighted the disruption of the biofilms and pore formation in bacterial cells exposed to both the plasma and acoustic treatments. Elevated reactive oxygen and nitrogen species in bacterial cells treated with atmospheric air plasma, demonstrated their primary role in the observed bacterial inactivation process. Our findings provide potential antimicrobial strategies to combat bacterial biofilms in the food and healthcare sectors.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Patange AD,Simpson JC,Curtin JF,Burgess CM,Cullen PJ,Tiwari BKdoi
10.1038/s41598-021-81977-zsubject
Has Abstractpub_date
2021-01-27 00:00:00pages
2346issue
1issn
2045-2322pii
10.1038/s41598-021-81977-zjournal_volume
11pub_type
杂志文章abstract：:Peripheral blood indices of systemic inflammation such as the neutrophil-lymphocyte ratio (NLR) have been shown to be prognostic in various cancers. We aim to investigate the clinical significance of these indices in patients with soft tissue sarcoma (STS). Seven hundred and twelve patients with available blood counts...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-30442-5
更新日期：2018-08-10 00:00:00
abstract：:We characterize the changes in chromatin structure, DNA methylation and transcription during and after homologous DNA repair (HR). We find that HR modifies the DNA methylation pattern of the repaired segment. HR also alters local histone H3 methylation as well chromatin structure by inducing DNA-chromatin loops connec...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep33222
更新日期：2016-09-15 00:00:00
abstract：:In this report, we propose and demonstrate an air-mode photonic crystal ring resonator (PhCRR) on silicon-on-insulator platform. Air mode is utilized to confine the optical field into photonic crystal (PhC) air holes, which is confirmed by the three-dimensional finite-difference time-domain simulation. PhCRR structure...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep19999
更新日期：2016-01-28 00:00:00
abstract：:O antigen (O-Ag) in many bacteria is synthesized via the Wzx/Wzy-dependent pathway in which Wzy polymerizes lipid-linked O-Ag subunits to modal lengths regulated by Wzz. Characterization of 83 site-directed mutants of Wzy from Pseudomonas aeruginosa PAO1 (WzyPa) in topologically-mapped periplasmic (PL) and cytoplasmic...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep03441
更新日期：2013-12-06 00:00:00
abstract：:Uric acid (UA) has been proposed as an important risk factor for cardiovascular and renal morbidity. We conducted an interventional trial to assess effects of altered salt intake on plasma and urine UA levels and the relationship between UA levels and salt sensitivity in humans. Ninety subjects (18-65 years old) were ...
journal_title：Scientific reports
pub_type： 临床试验,杂志文章
doi：10.1038/s41598-018-20048-2
更新日期：2018-01-23 00:00:00
abstract：:The aim of this study was to evaluate the impact of lymph node status from neck dissection pathological specimens on the survival for isolated regional nodal recurrence or persistence after primary treatment of nasopharyngeal carcinoma. Through a retrospective cohort study performed in an academic tertiary referral ho...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-62625-4
更新日期：2020-03-27 00:00:00
abstract：:We study a system of active particles with soft repulsive interactions that lead to an active cluster-crystal phase in two dimensions. We use two different modelizations of the active force - Active Brownian particles (ABP) and Ornstein-Uhlenbeck particles (AOUP) - and focus on analogies and differences between them. ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-52420-1
更新日期：2019-11-13 00:00:00
abstract：:Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive tumors with low survival rates and the leading cause of death in neurofibromatosis type 1 (NF1) patients under 40 years old. Surgical resection is the standard of care for MPNSTs, but is often incomplete and can generate loss of function, necessitating t...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep37035
更新日期：2016-11-11 00:00:00
abstract：:The role of the different lymphocyte populations in liver microenvironment of chronic hepatitis C (CHC) patients is still matter of debate. Since Th17 and Treg have opposite functions, their balance could affect disease progression. The aim was to explore liver microenvironment and its peripheral blood counterpart in ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-13777-3
更新日期：2017-10-16 00:00:00
abstract：:Recent paleoclimatic studies suggest that changes in the tropical rainbelt across the Atlantic Ocean during the past two millennia are linked to a latitudinal shift of the Intertropical Convergence Zone (ITCZ) driven by the Northern Hemisphere (NH) climate. However, little is known regarding other potential drivers th...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-38003-6
更新日期：2019-02-08 00:00:00
abstract：:In wild animal conservation, knowing the age of an individual animal is extremely beneficial. However, estimating the age is difficult for many species. Recently, epigenetics-based methods of estimating age have been reported. These studies were predominantly on humans with few reports on other animals, especially wil...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-28318-9
更新日期：2018-07-03 00:00:00
abstract：:Gelatin-coupled cellulose (GCC) microgel with whisker-like structure is prepared and used to incorporate into casein (CA) matrix to construct reinforced CA-based composite films by solution casting. The GCC microgel has excellent dispersibility and stability in water, which contributes to the hydrophobicity and signif...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-37848-1
更新日期：2019-02-04 00:00:00
abstract：:Large-area, pinhole-free CH3NH3PbI3 perovskite thin films were successfully fabricated on 5 cm × 5 cm flexible indium tin oxide coated polyethylene naphthalate (ITO-PEN) substrates through a sequential evaporation/spin-coating deposition method in this research. The influence of the rate-controlled evaporation of PbI2...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-18970-y
更新日期：2018-01-11 00:00:00
abstract：:Magnetic nanoparticles dissipate heat when exposed to alternating magnetic fields (AMFs), making them suitable for cancer hyperthermia. Therapeutic heating applications demand accurate characterization of the heating power dissipated by the particles. Specific loss power (SLP) generated by magnetic nanoparticles is es...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-07088-w
更新日期：2017-07-27 00:00:00
abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. ...
journal_title：Scientific reports
pub_type： 已发布勘误
doi：10.1038/s41598-019-43803-5
更新日期：2019-05-17 00:00:00
abstract：:Leukemia cells are superior to hematopoietic cells with a normal differentiation potential in buffering cellular stresses, but the underlying mechanisms for this leukemic advantage are not fully understood. Using CRISPR/Cas9 deletion of the canonical autophagy-essential gene Atg7, we found that erythroleukemia K562 ce...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep24641
更新日期：2016-04-19 00:00:00
abstract：:The interaction between two different materials can present novel phenomena that are quite different from the physical properties observed when each material stands alone. Strong electronic correlations, such as magnetism and superconductivity, can be produced as the result of enhanced Coulomb interactions between ele...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep21460
更新日期：2016-02-18 00:00:00
abstract：:The extracellular matrix (ECM) impacts stem cell differentiation, but identifying formulations supportive of differentiation is challenging in 3D models. Prior efforts involving combinatorial ECM arrays seemed intuitively advantageous. We propose an alternative that suggests reducing sample size and technological burd...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep18705
更新日期：2015-12-21 00:00:00
abstract：:With the development of ultra-intense laser technology, MeV ions can be obtained from laser-foil interactions in the laboratory. These energetic ion beams can be applied in fast ignition for inertial confinement fusion, medical therapy, and proton imaging. However, these ions are mainly accelerated in the laser propag...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep08274
更新日期：2015-02-05 00:00:00
abstract：:Artificial sheet materials, known as MetaSurfaces, have been applied to fully control both space and surface waves due to their exceptional abilities to dynamically tailor wave fronts and polarization states, while maintaining small footprints. However, previous and current designs and manufactured MetaSurfaces are li...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-36451-8
更新日期：2019-02-28 00:00:00
abstract：:Botulinum-toxin A (BoNT/A) is used for a wide range of conditions. Intramuscular administration of BoNT/A inhibits the release of acetylcholine at the neuromuscular junction from presynaptic motor neurons causing muscle-paralysis. The aim of the present study was to investigate the effect of high dose intramuscular Bo...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-14997-3
更新日期：2017-11-07 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-47315-0
更新日期：2019-08-02 00:00:00
abstract：:Somatic copy number alterations (SCNAs) affecting oncogenic drivers have a firmly established role in promoting cancer. However, no agreed-upon standard exists for calling locus-specific amplifications and deletions in each patient sample. Here, we report the correlative analysis of copy number amplitude and length wi...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep19649
更新日期：2016-01-20 00:00:00
abstract：:The Saccharomyces cerevisiae kinesin-5 Cin8 performs essential mitotic functions in spindle assembly and anaphase B spindle elongation. Recent work has shown that Cin8 is a bi-directional motor which moves towards the minus-end of microtubules (MTs) under high ionic strength (IS) conditions and changes directionality ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep25597
更新日期：2016-05-24 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep25919
更新日期：2016-05-18 00:00:00
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journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-45515-2
更新日期：2019-06-21 00:00:00
abstract：:Here, we report a newly designed knee plug to be used in the 3rd generation of Autologous Chondrocyte Implantation (ACI) in order to heal the damaged knee cartilage. It is composed of three components: The first component (Bone Portion) is a 3D printed hard scaffold with large pores (~ 850 µm), made by hydroxyapatite ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-73863-x
更新日期：2020-10-12 00:00:00
abstract：:Predation has driven the evolution of diverse adaptations for defence among prey, and one striking example is the deimatic display. While such displays can resemble, or indeed co-occur with, aposematic 'warning' signals, theory suggests deimatic displays may function independently of predator learning. The survival va...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-36995-9
更新日期：2019-01-24 00:00:00
abstract：:Maculinea (=Phengaris) are endangered butterflies that are characterized by a very complex biological cycle. Maculinea larvae behave as obligate parasites whose survival is strictly dependent on both particular food plants and species-specific Myrmica ants. In this interaction, Maculinea caterpillars induce Myrmica wo...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-44514-7
更新日期：2019-05-29 00:00:00
abstract：:Conventional solid lubricants such as MoS2, graphite, or diamond-like carbon films demonstrate excellent tribological performance but only in specific environments due to their inherent materials properties. This limitation prohibits using these solid lubricants in environments that change dynamically. This study pres...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-72666-4
更新日期：2020-09-21 00:00:00
