Biological significance and prognostic relevance of peripheral blood neutrophil-to-lymphocyte ratio in soft tissue sarcoma.

abstract：:Multifocal multiphoton microscopy (MMM) achieves fast imaging by simultaneously scanning multiple foci across different regions of specimen. The use of imaging detectors in MMM, such as CCD or CMOS, results in degradation of image signal-to-noise-ratio (SNR) due to the scattering of emitted photons. SNR can be partly ...

journal_title：Scientific reports

authors： Cha JW,Singh VR,Kim KH,Subramanian J,Peng Q,Yu H,Nedivi E,So PT

更新日期：2014-06-05 00:00:00

abstract：:Developing an alternative method for fabricating microscale graphene patterns that overcomes the obstacles of organic contamination, linewidth resolution, and substrate damaging is paramount for applications in optoelectronics. Here we propose to pattern chemical vapor deposition grown graphene film through a stencil ...

journal_title：Scientific reports

authors： Wu Y,Tao H,Su S,Yue H,Li H,Zhang Z,Ni Z,Chen X

更新日期：2017-04-19 00:00:00

abstract：:Genome-wide experiments to map the DNA-binding locations of transcription-associated factors (TFs) have shown that the number of genes bound by a TF far exceeds the number of possible direct target genes. Distinguishing functional from non-functional binding is therefore a major challenge in the study of transcription...

journal_title：Scientific reports

authors： Banks CJ,Joshi A,Michoel T

更新日期：2016-02-09 00:00:00

abstract：:Porous three-dimensional (3D) polyurethane-based biocomposites were produced utilizing diatomite and hydroxyapatite as fillers. Diatomite and Hydroxyapatite (HA) were utilized to reinforce the morphological, chemical, mechanical, and thermal properties of polyurethane foam (PUF). Diatomite and Hydroxyapatite were adde...

journal_title：Scientific reports

authors： Mustafov SD,Sen F,Seydibeyoglu MO

更新日期：2020-08-06 00:00:00

abstract：:Both heart rate (HR) and brain functioning involve the integrated output of a multitude of regulatory mechanisms, that are not quantified adequately by linear approximations such as means and standard deviations. It was therefore considered whether non-linear measures of HR complexity are more strongly associated with...

journal_title：Scientific reports

authors： Young H,Benton D

更新日期：2015-11-13 00:00:00

abstract：:Although protein-folding stress at the endoplasmic reticulum (ER) is emerging as a driver of neuronal dysfunction in models of spinal cord injury and neurodegeneration, the contribution of this pathway to peripheral nerve damage remains poorly explored. Here we targeted the unfolded protein response (UPR), an adaptive...

journal_title：Scientific reports

authors： Oñate M,Catenaccio A,Martínez G,Armentano D,Parsons G,Kerr B,Hetz C,Court FA

更新日期：2016-02-24 00:00:00

abstract：:The insect vector borne bacterium Xylella fastidiosa was first detected in olive trees in Southern Italy in 2013, and identified as the main culprit behind the 'olive quick decline syndrome'. Since then, the disease has spread rapidly through Italy's main olive oil producing region. The epidemiology of the outbreak is...

journal_title：Scientific reports

authors： Strona G,Carstens CJ,Beck PS

更新日期：2017-03-06 00:00:00

abstract：:Strenuous exercise increases circulating cell free DNA (cfDNA) and stimulates blood phagocytes to generate reactive oxygen species (ROS) which may induce DNA strand breaks. We tested whether: (A) elevated cfDNA in response to three repeated bouts of exhaustive exercise has decreased integrity; (B) each bout of exercis...

journal_title：Scientific reports

authors： Stawski R,Walczak K,Perdas E,Wlodarczyk A,Sarniak A,Kosielski P,Meissner P,Budlewski T,Padula G,Nowak D

更新日期：2019-11-04 00:00:00

abstract：:In the present work, we theoretically illuminate the excited state double proton transfer (ESDPT) process about a novel synthesized system 2,5-bis(benzoxazol-2-yl)thiophene-3,4-diol (BBTD). Minor changes of both structure and charge redistribution deriving from photoexcitation result in obviously different excited sta...

journal_title：Scientific reports

authors： Zhao J,Zheng Y

更新日期：2017-03-22 00:00:00

abstract：:Maternal low-protein (MLP) diet can lead to hepatic steatosis, which only develops with ageing. It is still unclear whether the young offspring show any signs of past exposure to prenatal adverse conditions. We hypothesized that early nutritional insult would first affect the dynamic responsiveness to nutritional chal...

journal_title：Scientific reports

authors： Sato N,Sudo K,Mori M,Imai C,Muramatsu M,Sugimoto M

更新日期：2017-08-29 00:00:00

abstract：:Leptin signaling in the hypothalamus plays a crucial role in the regulation of body weight. Leptin resistance, in which leptin signaling is disrupted, is a major obstacle to the improvement of obesity. We herein demonstrated that protein tyrosine phosphatase receptor type J (Ptprj) is expressed in hypothalamic neurons...

journal_title：Scientific reports

authors： Shintani T,Higashi S,Suzuki R,Takeuchi Y,Ikaga R,Yamazaki T,Kobayashi K,Noda M

更新日期：2017-09-14 00:00:00

abstract：:It is known that a developing avian embryo resorbs micronutrients (calcium and other chemical elements) from the inner layer of the eggshell, inducing thinning and overall changes in the shell's chemical composition. However, an aspect yet to be explored relates to the local changes in the multi-elemental composition ...

journal_title：Scientific reports

authors： Orłowski G,Niedzielski P,Merta D,Pokorny P,Proch J

更新日期：2020-12-17 00:00:00

abstract：:The biggest challenge in colorectal cancer therapy is to avoid intestinal drug absorption before reaching the colon, while focusing on tumor specific delivery with high local concentration and minimal toxicity. In our work, thymoquinone (TQ)-loaded polymeric nanocapsules were prepared using the nanoprecipitation techn...

journal_title：Scientific reports

authors： Ramzy L,Metwally AA,Nasr M,Awad GAS

更新日期：2020-07-03 00:00:00

abstract：:The discovery of the community structure of real-world networks is still an open problem. Many methods have been proposed to shed light on this problem, and most of these have focused on discovering node community. However, link community is also a powerful framework for discovering overlapping communities. Here we pr...

journal_title：Scientific reports

authors： Liu W,Jiang X,Pellegrini M,Wang X

更新日期：2016-03-01 00:00:00

abstract：:Bragg coherent X-ray diffraction imaging (BCDI) has emerged as a powerful technique to image the local displacement field and strain in nanocrystals, in three dimensions with nanometric spatial resolution. However, BCDI relies on both dataset collection and phase retrieval algorithms that can induce artefacts in the r...

journal_title：Scientific reports

authors： Carnis J,Gao L,Labat S,Kim YY,Hofmann JP,Leake SJ,Schülli TU,Hensen EJM,Thomas O,Richard MI

更新日期：2019-11-22 00:00:00

abstract：:Mass spectrometry (MS) for the detection of proteins is an indispensable tool for evaluating the biological processes of the proteome. Proteomics frequently requires proteolysis of proteins into peptide fragments. Proteins can be refractory to ideal proteolysis at the sequence level rendering them difficult to analyze...

journal_title：Scientific reports

authors： Reyna C,Mba Medie F,Champion MM,Champion PA

更新日期：2016-09-14 00:00:00

abstract：:Anserine/carnosine supplementation improves cerebral blood flow and verbal episodic memory in elderly people, as we previously reported. Anserine's buffering activity is superior to that of carnosine at neutral pH. In human sera, carnosine but not anserine is rapidly cleaved by carnosinase, limiting its effectiveness....

journal_title：Scientific reports

authors： Kaneko J,Enya A,Enomoto K,Ding Q,Hisatsune T

更新日期：2017-10-03 00:00:00

abstract：:The natural ligand 17β-estradiol (E2) is so far believed to induce a unique agonist-bound active conformation in the ligand binding domain (LBD) of the estrogen receptors (ERs). Both subtypes, ERα and ERβ, are transcriptionally activated in the presence of E2 with ERβ being somewhat less active than ERα under similar ...

journal_title：Scientific reports

authors： Souza PCT,Textor LC,Melo DC,Nascimento AS,Skaf MS,Polikarpov I

更新日期：2017-06-14 00:00:00

abstract：:A new semiconducting phase of two-dimensional phosphorous in the Kagome lattice is proposed from first-principles calculations. The band gaps of the monolayer (ML) and bulk Kagome phosphorous (Kagome-P) are 2.00 and 1.11 eV, respectively. The magnitude of the band gap is tunable by applying the in-plane strain and/or ...

journal_title：Scientific reports

authors： Chen PJ,Jeng HT

更新日期：2016-03-16 00:00:00

abstract：:Subduction zones facilitate chemical exchanges between Earth's deep interior and volcanism that affects habitability of the surface environment. Lavas erupted at subduction zones are oxidized and release volatile species. These features may reflect a modification of the oxidation state of the sub-arc mantle by hydrous...

journal_title：Scientific reports

authors： Debret B,Sverjensky DA

更新日期：2017-09-04 00:00:00

abstract：:This study presents a modular-based implementation of augmented reality to provide an immersive experience in learning or teaching the planning phase, control system, and machining parameters of a fully automated work cell. The architecture of the system consists of three code modules that can operate independently or...

journal_title：Scientific reports

authors： Pai YS,Yap HJ,Md Dawal SZ,Ramesh S,Phoon SY

更新日期：2016-06-07 00:00:00

abstract：:The order Chlamydiales are biphasic intracellular bacterial pathogens infecting humans and domesticated animals. Wildlife infections have also been reported, with the most studied example being Chlamydia pecorum infections in the koala, an iconic Australian marsupial. In koalas, molecular evidence suggests that spill-...

journal_title：Scientific reports

authors： Burnard D,Huston WM,Webb JK,Jelocnik M,Reiss A,Gillett A,Fitzgibbon S,Carver S,Carrucan J,Flanagan C,Timms P,Polkinghorne A

更新日期：2017-10-09 00:00:00

abstract：:A scheme is presented to realize a single-photon transistor based on cavity quantum electrodynamics (QED) with Rydberg atomic ensemble. By combining the advantages of the cavity-enhanced interaction and Rydberg blockade, we achieve a high gain single-photon transistor. The numerical calculation shows that by using one...

journal_title：Scientific reports

authors： Hao YM,Lin GW,Lin XM,Niu YP,Gong SQ

更新日期：2019-03-18 00:00:00

abstract：:Stochastic surface patterns form an important requirement to facilitate digital image correlation and to subsequently quantify material properties of various tissues when loaded and deformed without artefacts arising from material slippage. Depending on the samples' natural colour, a surface pattern is created by spec...

journal_title：Scientific reports

authors： Zwirner J,Ondruschka B,Scholze M,Hammer N

更新日期：2020-11-27 00:00:00

abstract：:We demonstrate theoretically that photon-photon attraction can be engineered in the continuum of scattering states for pairs of photons propagating in a hollow-core photonic crystal fiber filled with cold atoms. The atoms are regularly spaced in an optical lattice configuration and the photons are resonantly tuned to ...

journal_title：Scientific reports

authors： Litinskaya M,Tignone E,Pupillo G

更新日期：2016-05-12 00:00:00

abstract：:Real-time Precise Point Positioning (PPP) technique is being widely applied for providing precise positioning services with the significant improvement on satellite precise products accuracy. With the rapid development of the multi-constellation Global Navigation Satellite Systems (multi-GNSS), currently, about 80 nav...

journal_title：Scientific reports

authors： Gao Z,Shen W,Zhang H,Niu X,Ge M

更新日期：2016-07-29 00:00:00

abstract：:Despite the development of crystal engineering, it remains a great challenge to predict the crystal structure even for the simplest molecules, and a clear link between molecular and crystal symmetry is missing in general. Here we demonstrate that the two-dimensional (2D) crystallization of heterocirculenes on a Au(111...

journal_title：Scientific reports

authors： Xiao WD,Zhang YY,Tao L,Aït-Mansour K,Chernichenko KY,Nenajdenko VG,Ruffieux P,Du SX,Gao HJ,Fasel R

更新日期：2014-06-24 00:00:00

abstract：:Epilepsy is a chronic neurological disease with a variable therapeutic response. To design effective treatment strategies for epilepsy, it is important to understand treatment responses and predictive factors. However, limited data are available in Africa, including Ethiopia. The aim of this study was therefore to ass...

journal_title：Scientific reports

authors： Gidey K,Chelkeba L,Gemechu TD,Daba FB

更新日期：2019-11-07 00:00:00

abstract：:Successful tick feeding is facilitated by an assortment of pharmacologically-active factors in tick saliva that create an immunologically privileged micro-environment in the host's skin. Through a process known as saliva-assisted transmission, bioactive tick salivary factors modulate the host environment, promoting tr...

journal_title：Scientific reports

authors： Hermance ME,Widen SG,Wood TG,Thangamani S

更新日期：2019-09-11 00:00:00

abstract：:The deregulation of autophagy is involved in liver regeneration. Here, we investigated the role of autophagy in the regulation of liver regeneration after partial hepatectomy (PHx) and the development of pharmacological interventions for improved liver regeneration after PHx. We show that autophagy was activated in th...

journal_title：Scientific reports

authors： Lin CW,Chen YS,Lin CC,Chen YJ,Lo GH,Lee PH,Kuo PL,Dai CY,Huang JF,Chung WL,Yu ML

更新日期：2015-10-30 00:00:00