Amiodarone as an autophagy promoter reduces liver injury and enhances liver regeneration and survival in mice after partial hepatectomy.

abstract：:Activated coke (AC) has great potential in the field of low-temperature NO removal (DeNOx), especially the branch prepared by blending modification. In this study, the AC-based pyrolusite and/or titanium ore blended catalysts were prepared and applied for DeNOx. The results show blending pyrolusite and titanium ore pr...

journal_title：Scientific reports

authors： Yang L,Yao L,Lai Y,Jiang X,Jiang W

更新日期：2020-11-10 00:00:00

abstract：:Materials' mechanical properties highly depend on their internal structures. Designing novel structure is an effective route to improve materials' performance. One-dimensional disordered (ODD) structure is a kind of particular structure in silicon carbide (SiC), which highly affects its mechanical properties. Herein, ...

journal_title：Scientific reports

authors： Zhang X,Wang J,Yang Z,Tang X,Yue Y

更新日期：2020-07-09 00:00:00

abstract：:Global change is predicted to cause shifts in species distributions and biodiversity in arctic tundra. We applied factorial warming and nutrient manipulation to a nutrient and species poor alpine/arctic heath community for seven years. Vascular plant abundance in control plots increased by 31%. There were also notable...

journal_title：Scientific reports

authors： Alatalo JM,Little CJ,Jägerbrand AK,Molau U

更新日期：2015-05-07 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. ...

journal_title：Scientific reports

authors： Ribeiro MBT,Guzzoni V,Hord JM,Lopes GN,de Cássia Marqueti R,de Andrade RV,Selistre-de-Araujo HS,Durigan JLQ

更新日期：2019-04-17 00:00:00

abstract：:To date, analyses of individual targets have provided evidence of a miRNA targetome that extends beyond the boundaries of messenger RNAs (mRNAs) and can involve non-Watson-Crick base pairing in the miRNA seed region. Here we report our findings from analyzing 34 Argonaute HITS-CLIP datasets from several human and mous...

journal_title：Scientific reports

authors： Clark PM,Loher P,Quann K,Brody J,Londin ER,Rigoutsos I

更新日期：2014-08-08 00:00:00

abstract：:Due to their multipotentiality and immunomodulation, human mesenchymal stem cells (hMSCs) are widely studied for the treatment of degenerative and inflammatory diseases. Transplantation of hMSCs to damaged tissue is a promising approach for tissue regeneration. However, the physiological mechanisms and regulatory proc...

journal_title：Scientific reports

authors： Kim SH,Das A,Chai JC,Binas B,Choi MR,Park KS,Lee YS,Jung KH,Chai YG

更新日期：2016-07-22 00:00:00

abstract：:Predicting the hosts of newly discovered viruses is important for pandemic surveillance of infectious diseases. We investigated the use of alignment-based and alignment-free methods and support vector machine using mononucleotide frequency and dinucleotide bias to predict the hosts of viruses, and applied these approa...

journal_title：Scientific reports

authors： Li H,Sun F

更新日期：2018-07-03 00:00:00

abstract：:There is a growing appreciation for the diverse regulatory consequences of the family of proteins that bind to the secondary channel of E. coli RNA polymerase (RNAP), such as GreA, GreB or DksA. Similar binding sites could suggest a competition between them. GreA is characterised to rescue stalled RNAP complexes due t...

journal_title：Scientific reports

authors： Fernández-Coll L,Potrykus K,Cashel M,Balsalobre C

更新日期：2020-09-30 00:00:00

abstract：:Rapid diagnostic tests (RDTs) have been widely deployed in low-resource settings. These tests are typically read by visual inspection, and accurate record keeping and data aggregation remains a substantial challenge. A successful malaria elimination campaign will require new strategies that maximize the sensitivity of...

journal_title：Scientific reports

authors： Scherr TF,Gupta S,Wright DW,Haselton FR

更新日期：2016-06-27 00:00:00

abstract：:Intrahepatic cholestasis induced by drug toxicity, bile salt export pump (BSEP) deficiency, or pregnancy frequently causes cholestatic liver damage, which ultimately may lead to liver fibrosis and cirrhosis. Here, the preventive and therapeutic effects of peroxisome proliferator-activated receptor α (PPARα) signaling ...

journal_title：Scientific reports

authors： Zhao Q,Yang R,Wang J,Hu DD,Li F

更新日期：2017-08-30 00:00:00

abstract：:Cancer cachexia is a complex multi-organ syndrome characterized by body weight loss, weakness, muscle atrophy and fat depletion. With a prevalence of 1 million people in Europe and only limited therapeutic options, there is a high medical need for new approaches to treat cachexia. Our latest results highlighted microb...

journal_title：Scientific reports

authors： Pötgens SA,Brossel H,Sboarina M,Catry E,Cani PD,Neyrinck AM,Delzenne NM,Bindels LB

更新日期：2018-08-17 00:00:00

abstract：:We propose a reflection type metal-insulator-metal (MIM) metasurface composed of hybrid nano-antennas for comprehensive spatial engineering of the properties of optical fields. The capability of such structure is illustrated in the design of a device that can be used to produce a radially polarized vectorial beam for ...

journal_title：Scientific reports

authors： Wang S,Zhan Q

更新日期：2016-07-15 00:00:00

abstract：:We hereby report for the first time on the design, manufacturing and testing of a three-dimensional (3D) nearly-periodic, locally resonant phononic crystal (PnC). Most of the research effort on PnCs and metamaterials has been focused on the enhanced dynamic properties arising from their periodic design. Lately, additi...

journal_title：Scientific reports

authors： Meng H,Bailey N,Chen Y,Wang L,Ciampa F,Fabro A,Chronopoulos D,Elmadih W

更新日期：2020-11-04 00:00:00

abstract：:Cartilage engineering that combines competent seeding cells and a compatible scaffold is increasingly gaining popularity and is potentially useful for the treatment of various bone and cartilage diseases. Intensive efforts have been made by researchers to improve the viability and functionality of seeding cells of eng...

journal_title：Scientific reports

authors： Ma Y,Li J,Yao Y,Wei D,Wang R,Wu Q

更新日期：2016-05-25 00:00:00

abstract：:Plasma dipeptidyl-peptidase-4 activity (DPP4a) is inversely associated with left ventricular function in patients with heart failure (HF) or diabetes. However, the association between DPP4a and left ventricular function in ST-segment elevation myocardial infarction (STEMI) patients has not been reported. We studied th...

journal_title：Scientific reports

authors： Li JW,Chen YD,Liu YQ,Wang JD,Chen WR,Zhang YQ,Ma Q

更新日期：2017-07-21 00:00:00

abstract：:A large volcanic sulfate increase observed in ice core records around 1450 C.E. has been attributed in previous studies to a volcanic eruption from the submarine Kuwae caldera in Vanuatu. Both EPMA-WDS (electron microprobe analysis using a wavelength dispersive spectrometer) and SEM-EDS (scanning electron microscopy a...

journal_title：Scientific reports

authors： Hartman LH,Kurbatov AV,Winski DA,Cruz-Uribe AM,Davies SM,Dunbar NW,Iverson NA,Aydin M,Fegyveresi JM,Ferris DG,Fudge TJ,Osterberg EC,Hargreaves GM,Yates MG

更新日期：2019-10-08 00:00:00

abstract：:Apolipoprotein E4 (E4) and type 2 diabetes are major risk factors for cognitive decline and late onset Alzheimer's disease (AD). E4-associated phenotypes and insulin resistance (IR) share several features and appear to interact in driving cognitive dysfunction. However, shared mechanisms that could explain their overl...

journal_title：Scientific reports

authors： Johnson LA,Torres ER,Impey S,Stevens JF,Raber J

更新日期：2017-03-08 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper. ...

journal_title：Scientific reports

authors： de Genaro IS,de Almeida FM,Hizume-Kunzler DC,Moriya HT,Silva RA,Cruz JCG,Lopes RB,Righetti RF,de Paula Vieira R,Saiki M,Martins MA,Tibério IFLC,Arantes-Costa FM,Saraiva-Romanholo BM

更新日期：2018-12-12 00:00:00

abstract：:Centenarians exhibit extreme longevity and a remarkable compression of morbidity. They have a unique capacity to maintain homeostatic mechanisms. Since small non-coding RNAs (including microRNAs) are implicated in the regulation of gene expression, we hypothesised that longevity of centenarians may reflect alterations...

journal_title：Scientific reports

authors： Serna E,Gambini J,Borras C,Abdelaziz KM,Belenguer A,Sanchis P,Avellana JA,Rodriguez-Mañas L,Viña J

更新日期：2012-01-01 00:00:00

abstract：:Priming improves an organism's performance upon a future stress. To test whether cold priming supports protection in spring and how it is affected by cold acclimation, we compared seven Arabidopsis accessions with different cold acclimation potentials in the field and in the greenhouse for growth, photosynthetic perfo...

journal_title：Scientific reports

authors： Cvetkovic J,Müller K,Baier M

更新日期：2017-03-09 00:00:00

abstract：:Cardiac damage associated with iron overload is the most common cause of morbidity and mortality in patients with hereditary hemochromatosis, but the precise mechanisms leading to disease progression are largely unexplored. Here we investigated the effects of iron overload and age on cardiac hypertrophy using 1-, 5- a...

journal_title：Scientific reports

authors： Sukumaran A,Chang J,Han M,Mintri S,Khaw BA,Kim J

更新日期：2017-07-18 00:00:00

abstract：:Next generation sequencing panels have been developed for hereditary cancer, although there is some debate about their cost-effectiveness compared to exome sequencing. The performance of two panels is compared to exome sequencing. Twenty-four patients were selected: ten with identified mutations (control set) and four...

journal_title：Scientific reports

authors： Feliubadaló L,Tonda R,Gausachs M,Trotta JR,Castellanos E,López-Doriga A,Teulé À,Tornero E,Del Valle J,Gel B,Gut M,Pineda M,González S,Menéndez M,Navarro M,Capellá G,Gut I,Serra E,Brunet J,Beltran S,Lázaro C

更新日期：2017-01-04 00:00:00

abstract：:Shewanella species are facultative anaerobic bacteria that colonize redox-stratified habitats where O2 and nutrient concentrations fluctuate. The model species Shewanella oneidensis MR-1 possesses genes coding for three terminal oxidases that can perform O2 respiration: a bd-type quinol oxidase and cytochrome c oxidas...

journal_title：Scientific reports

authors： Le Laz S,Kpebe A,Bauzan M,Lignon S,Rousset M,Brugna M

更新日期：2016-01-27 00:00:00

abstract：:The foregut endoderm gives rise to several organs including liver, pancreas, lung and thyroid with important roles in human physiology. Understanding which genes and signalling pathways regulate their development is crucial for understanding developmental disorders as well as diseases in adulthood. We exploited unique...

journal_title：Scientific reports

authors： Trubiroha A,Gillotay P,Giusti N,Gacquer D,Libert F,Lefort A,Haerlingen B,De Deken X,Opitz R,Costagliola S

更新日期：2018-04-04 00:00:00

abstract：:Maize rough dwarf virus (MRDV) is one of the main yield-limiting factors of maize in the Mediterranean. However, knowledge about the interactions between the agroecosystem and the virus-vector-host relationship continues to be limited. We used multi-model inference to test a landscape-scale approach together with vari...

journal_title：Scientific reports

authors： Clemente-Orta G,Albajes R,Batuecas I,Achon MA

更新日期：2021-01-13 00:00:00

abstract：:Nano-flowers reported so far were mostly constituted of inorganic or hybrid materials. We have synthesized and crystallized a new organic compound, 1, 2-bis(tritylthio)ethane forming an organic nano-flower consisting of single crystalline petals. Crystal structure at nano and micro level indicates that π-π stacking in...

journal_title：Scientific reports

authors： Sasidharan S,P C S,Chaudhary N,Ramakrishnan V

更新日期：2017-12-11 00:00:00

abstract：:Fusion transcripts can contribute to diversity of molecular networks in the human cortex. In this study, we explored the occurrence of fusion transcripts in normal human cortex along with single neurons and astrocytes. We identified 1305 non-redundant fusion events from 388 transcriptomes representing 59 human cortice...

journal_title：Scientific reports

authors： Mehani B,Narta K,Paul D,Raj A,Kumar D,Sharma A,Kaurani L,Nayak S,Dash D,Suri A,Sarkar C,Mukhopadhyay A

更新日期：2020-01-28 00:00:00

abstract：:Head and neck squamous cell carcinoma (HNSCC) development is a multistage process includes the normal, dysplasia and squamous cell carcinoma (SCC) stages. Recently, increasing evidence has suggested that the tumor microenvironment (TME) is an integral part of malignant transformation. Exploring certain key node genes ...

journal_title：Scientific reports

authors： Wu T,Hong Y,Jia L,Wu J,Xia J,Wang J,Hu Q,Cheng B

更新日期：2016-02-01 00:00:00

abstract：:Salivary duct carcinoma (SDC) is an uncommon, but aggressive malignant tumor with a high mortality rate. Herein, we reported the detection of somatic KRAS A146T and Q61H mutations in 2 out of 4 (50%) sarcomatoid SDC variants. Transgenic mice carrying the human oncogenic KRAS(G12V), which spatiotemporal activation by t...

journal_title：Scientific reports

authors： Fu Y,Cruz-Monserrate Z,Helen Lin H,Chung Y,Ji B,Lin SM,Vonderfecht S,Logsdon CD,Li CF,Ann DK

更新日期：2015-08-20 00:00:00

abstract：:The activation of the majority of AGC kinases is regulated by two phosphorylation events on two conserved serine/threonine residues located on the activation loop and on the hydrophobic motif, respectively. In AGC kinase family, phosphomimetic substitutions with aspartate or glutamate, leading to constitutive activati...

journal_title：Scientific reports

authors： Somale D,Di Nardo G,di Blasio L,Puliafito A,Vara-Messler M,Chiaverina G,Palmiero M,Monica V,Gilardi G,Primo L,Gagliardi PA

更新日期：2020-01-17 00:00:00