Abstract:
:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Ribeiro MBT,Guzzoni V,Hord JM,Lopes GN,de Cássia Marqueti R,de Andrade RV,Selistre-de-Araujo HS,Durigan JLQdoi
10.1038/s41598-019-42462-wsubject
Has Abstractpub_date
2019-04-17 00:00:00pages
6383issue
1issn
2045-2322pii
10.1038/s41598-019-42462-wjournal_volume
9pub_type
已发布勘误abstract::In this study, the effect of post-deposition tetrafluoromethane (CF4) plasma treatment on the physical and electrical characteristics of an In2TiO5 based electrolyte-insulator-semiconductor (EIS) sensor was investigated. Post-deposition CF4 plasma treatment typically improved the crystalline structure and repaired dan...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-39012-9
更新日期:2019-02-28 00:00:00
abstract::The General Unified Threshold model for Survival (GUTS) integrates previously published toxicokinetic-toxicodynamic models and estimates survival with explicitly defined assumptions. Importantly, GUTS accounts for time-variable exposure to the stressor. We performed three studies to test the ability of GUTS to predict...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep29178
更新日期:2016-07-06 00:00:00
abstract::Inhibition of DYRK1A kinase, produced by chromosome 21 and consequently overproduced in trisomy 21 subjects, has been suggested as a therapeutic approach to treating the cognitive deficiencies observed in Down syndrome (DS). We now report the synthesis and potent DYRK1A inhibitory activities of fluoro derivatives of 3...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-20984-z
更新日期:2018-02-12 00:00:00
abstract::Novel mesoporous silicas rolled with silica sheets with 2D regular spacing were prepared using a self-assembled graphene oxide (GO) template formed by mixing GO with Pluronic123 (P123). Self-assembled GO templated mesoporous silicas (SGT-PMS) showed well-developed X-ray diffraction peaks with d-spacings of 9.8-10.8 nm...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-63017-4
更新日期:2020-04-10 00:00:00
abstract::Turner Syndrome (TS) is a condition where several genes are affected but the molecular mechanism remains unknown. Identifying the genes that regulate the TS network is one of the main challenges in understanding its aetiology. Here, we studied the regulatory network from manually curated genes reported in the literatu...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-28375-0
更新日期:2018-07-04 00:00:00
abstract::Ceramide, a bioactive lipid and signaling molecule associated with cardiovascular disease, is known to activate extracellular signal regulated kinases 1 and 2 (ERK1/2). Here, we determined that the effect of ceramide on ERK1/2 is mediated by ceramide signaling on an ERK scaffold protein, IQ motif containing GTPase act...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-09434-4
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abstract::Myodural bridges have been described in various species as connective tissue structures "bridging" small cranio-cervical muscles to the dura. Myodural bridges are thought to stabilize the dural sac during head and neck movements and promote cerebrospinal fluid motion; however, their role in neurological diseases has n...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-46444-w
更新日期:2019-07-10 00:00:00
abstract::Cell fate decisions are controlled by the interplay of transcription factors and epigenetic modifiers, which together determine cellular identity. Here we elaborate on the role of miR302 in the regulation of cell plasticity. Overexpression of miR302 effected silencing of the TGFβ type II receptor and facilitated plast...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep42407
更新日期:2017-02-14 00:00:00
abstract::Plant resistance can provide effective, economical, and sustainable pest control. Tolerance to the soybean aphid has been identified and confirmed in the soybean KS4202. Although its resistance mechanisms are not fully understood, evidence suggests that enhanced detoxification of reactive oxygen species (ROS) is an ac...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-33477-w
更新日期:2018-10-11 00:00:00
abstract::We quantitatively evaluated breast tumor movement and volume changes between magnetic resonance imaging (MRI) scans in prone and supine positions. Twenty-seven breast tumor patients who received neoadjuvant systemic therapy (NST) for breast-conserving surgery were studied. Before and after NST, MRI scans in prone and ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-61802-9
更新日期:2020-03-17 00:00:00
abstract::Extraction of mouse spinal motor neurons from transgenic mouse embryos recapitulating some aspects of neurodegenerative diseases like amyotrophic lateral sclerosis has met with limited success. Furthermore, extraction and long-term culture of adult mouse spinal motor neurons and glia remain also challenging. We presen...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep16763
更新日期:2015-11-18 00:00:00
abstract::Chromosomal toxin-antitoxin (TA) systems are widespread genetic elements among bacteria, yet, despite extensive studies in the last decade, their biological importance remains ambivalent. The ability of TA-encoded toxins to affect stress tolerance when overexpressed supports the hypothesis of TA systems being associat...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-65504-0
更新日期:2020-06-08 00:00:00
abstract::In cytochrome c oxidase (CytcO) reduction of O2 to water is linked to uptake of eight protons from the negative side of the membrane: four are substrate protons used to form water and four are pumped across the membrane. In bacterial oxidases, the substrate protons are taken up through the K and the D proton pathways,...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-56648-9
更新日期:2019-12-27 00:00:00
abstract::Hysteresis, which is the history dependence of physical systems, is one of the most important topics in physics. Interestingly, bi-stability of plasma with a huge hysteresis loop has been observed in inductive plasma discharges. Despite long plasma research, how this plasma hysteresis occurs remains an unresolved ques...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep15254
更新日期:2015-10-20 00:00:00
abstract::The dermal striated muscle panniculus carnosus (PC), prevalent in lower mammals with remnants in humans, is highly regenerative, and whose function is purported to be linked to defence and shivering thermogenesis. Given the heterogeneity of responses of different muscles to disease, we set out to characterize the PC i...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-52071-2
更新日期:2019-11-04 00:00:00
abstract::The distinction between primary and secondary volcaniclastic deposits, which are currently defined as the "direct" products of volcanic eruptions and the "reworked" products of the former, respectively, is the first step to interpreting volcaniclastic deposits, particularly the genetic connection with active volcanism...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-48933-4
更新日期:2019-08-27 00:00:00
abstract::Hematopoietic stem/progenitor cells (HSPC) in zebrafish emerge from the aortic hemogenic endothelium (HE) and migrate towards the caudal hematopoietic tissue (CHT), where they expand and differentiate during definitive hematopoiesis. Phospholipase C gamma 1 (Plcγ1) has been implicated for hematopoiesis in vivo and in ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-36338-8
更新日期:2019-01-21 00:00:00
abstract::Intrahepatic cholangiocarcinoma (IHCC) is a highly aggressive malignancy with a poor prognosis. It is thought to originate from cholangiocytes, which are the component cells of intrahepatic bile ducts. However, as patients with viral hepatitis often develop IHCC, it has been suggested that transformed hepatocytes may ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-21121-6
更新日期:2018-02-12 00:00:00
abstract::Concerns related to pulmonary toxicity and non-specificity of nanoparticles have limited their clinical applications for aerosol delivery of chemotherapeutics in lung cancer. We hypothesized that pulmonary surfactant mimetic nanoparticles that offer pH responsive release specifically in tumor may be a possible solutio...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep07085
更新日期:2014-11-18 00:00:00
abstract::A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper. ...
journal_title:Scientific reports
pub_type: 已发布勘误
doi:10.1038/s41598-018-32187-7
更新日期:2018-09-26 00:00:00
abstract::An aberrant expression of integrin β1 has been implicated in breast cancer progression. Here, we compared the cell behaviors of wild-type (WT), β1 gene deleted (KO), and β1 gene restored (Res) MDA-MB-231 cells. Surprisingly, the expression of β1 exhibited opposite effects on cell proliferation. These effects were depe...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep18430
更新日期:2016-01-05 00:00:00
abstract::Transient gene expression approaches are valuable tools for rapid introduction of genes of interest and characterization of their functions in plants. Although agroinfiltration is the most effectively and routinely used method for transient expression of multiple genes in various plant species, this approach has been ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep22436
更新日期:2016-02-29 00:00:00
abstract::Dielectric Discharge Barrier (DBD) plasma actuators are considered as one of the best active electro-hydrodynamic control devices, and are considered by many contemporary researchers. Here a simple electrostatic model, which is improved by authors, and uses the Maxwell's and the Navier-Stokes equations, is proposed fo...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-75419-5
更新日期:2020-11-02 00:00:00
abstract::William Adams (Miura Anjin) was an English navigator who sailed with a Dutch trading fleet to the far East and landed in Japan in 1600. He became a vassal under the Shogun, Tokugawa Ieyasu, was bestowed with a title, lands and swords, and became the first SAMURAI from England. "Miura" comes from the name of the territ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-78723-2
更新日期:2020-12-10 00:00:00
abstract::Understanding ethanol-induced stresses and responses in biofuel-producing bacteria at systems level has significant implications in engineering more efficient biofuel producers. We present a computational study of transcriptomic and genomic data of both ethanol-stressed and ethanol-adapted E. coli cells with computati...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep44150
更新日期:2017-03-16 00:00:00
abstract::Baeyer-Villiger monooxygenases (BVMOs) can be used for the biosynthesis of lactones and esters from ketones. However, the BVMO-based biocatalysts are not so stable under process conditions. Thereby, this study focused on enhancing stability of the BVMO-based biocatalysts. The biotransformation of ricinoleic acid into ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-28575-8
更新日期:2018-07-06 00:00:00
abstract::Recent evidence suggests that some seizures are preceded by preictal changes that start from minutes to hours before an ictal event. Nevertheless an adequate statistical evaluation in a large database of continuous multiday recordings is still missing. Here, we investigated the existence of preictal changes in long-te...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep04545
更新日期:2014-04-01 00:00:00
abstract::High-density linkage maps can improve the precision of QTL localization. A high-density SNP-based linkage map containing 3207 markers covering 3072.7 cM of the Brassica napus genome was constructed in the KenC-8 × N53-2 (KNDH) population. A total of 67 and 38 QTLs for seed oil and protein content were identified with ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep46295
更新日期:2017-04-10 00:00:00
abstract::Flotation of small solid objects and liquid droplets on water is critical to natural and industrial activities. This paper reports the floating mechanism of liquid marbles, or liquid droplets coated with hydrophobic microparticles. We used X-ray computed tomography (XCT) to acquire cross-sectional images of the floati...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep21777
更新日期:2016-02-23 00:00:00
abstract::Leukocyte-platelet rich fibrin (L-PRF) is extensively used in the dentistry field and other clinical scenarios due to its regeneration properties. The goal of the present study was to depict the L-PRF secretome and how it changes over time. We obtained L-PRF membranes and cultured them in DMEM. The secretome was colle...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-71419-7
更新日期:2020-09-03 00:00:00