Abstract:
:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper.
journal_name
Sci Repjournal_title
Scientific reportsauthors
de Genaro IS,de Almeida FM,Hizume-Kunzler DC,Moriya HT,Silva RA,Cruz JCG,Lopes RB,Righetti RF,de Paula Vieira R,Saiki M,Martins MA,Tibério IFLC,Arantes-Costa FM,Saraiva-Romanholo BMdoi
10.1038/s41598-018-36667-8subject
Has Abstractpub_date
2018-12-12 00:00:00pages
17899issue
1issn
2045-2322pii
10.1038/s41598-018-36667-8journal_volume
8pub_type
已发布勘误abstract::Prostate-specific antigen (PSA) kinetics predicts survival in castration-resistant prostate cancer (CRPC); however, the influence of prior treatment on this relationship is unclear. Patients with CRPC were stratified according to time to PSA nadir and time to CRPC progression to investigate their prognostic significan...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-48424-6
更新日期:2019-08-15 00:00:00
abstract::Combining chemotherapy and targeted therapies has resulted in an enhanced survival in metastatic colorectal cancer (mCRC) patients. However, the result of this palliative treatment in patients with metachronous peritoneal carcinomatosis (PC) remains unknown. The current population-based study aims to investigate the u...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep18632
更新日期:2015-12-21 00:00:00
abstract::Converging evidence supports the involvement of pro-inflammatory pathways and the gut microbiome in major depressive disorder (MDD). Pre-clinical and clinical studies suggest that decreasing pro-inflammatory signaling may provide clinical benefit in MDD. In this study, we used the chronic unpredictable stress (CUS) pa...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-38055-8
更新日期:2019-04-23 00:00:00
abstract::Escherichia coli and Salmonella Enteritidis are foodborne pathogens forming challenging biofilms that contribute to their virulence, antimicrobial resistance, and survival on surfaces. Interspecies interactions occur between species in mixed biofilms promoting different outcomes to each species. Here we describe the i...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-54847-y
更新日期:2019-12-03 00:00:00
abstract::The finding that mature forest ecosystems increase carbon in woody tissues and mineral soils indicates that the original equilibriums are being pushed to a higher state. The final driving forces will probably be increasing CO2 and nitrogen deposition, global warming, and changes to precipitation patterns. However, whi...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep03681
更新日期:2014-01-14 00:00:00
abstract::Plant litter represents a major basal resource in streams, where its decomposition is partly regulated by litter traits. Litter-trait variation may determine the latitudinal gradient in decomposition in streams, which is mainly microbial in the tropics and detritivore-mediated at high latitudes. However, this hypothes...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-10640-3
更新日期:2017-09-05 00:00:00
abstract::Bisphenol A (BPA), a member of the environmental endocrine disruptors (EDCs), has recently received increased attention because of its effects on brain insulin resistance. Available data have indicated that brain insulin resistance may contribute to neurodegenerative diseases. However, the associated mechanisms that u...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-07544-7
更新日期:2017-08-08 00:00:00
abstract::Depression is a common mental illness with complex and heterogeneous progression dynamics. Risk grouping of depression treatment population based on their longitudinal patterns has the potential to enable cost-effective monitoring policy design. This paper establishes a rule-based method to identify a set of risk pred...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-23326-1
更新日期:2018-03-22 00:00:00
abstract::The purpose of this paper is to develop a lightweight apron that will be used for shielding low intensity radiation in medical imaging radiography room and to apply it to a custom-made effective shielding. The quality of existing aprons made for protecting our bodies from direct radiation are improved so that they are...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep27721
更新日期:2016-07-27 00:00:00
abstract::Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection is currently a global pandemic, and there are limited laboratory studies targeting pathogen resistance. This study aimed to investigate the effect of selected disinfection products and methods on the inactivation of SARS-CoV-2 in the laboratory. We...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-021-82148-w
更新日期:2021-01-28 00:00:00
abstract::Glomerular mesangial cell (GMC) proliferation and matrix expansion are pathological hallmarks of a wide range of kidney diseases, including diabetic nephropathy. Although the circulating level of peptide hormone urotensin II (UII) and kidney tissue expression of UII and UII receptors (UTR) are increased in diabetic ne...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-18143-x
更新日期:2017-12-22 00:00:00
abstract::The present study aimed to evaluate the accuracy and repeatability of morphological contour interpolation (MCI)-based semiautomatic segmentation method for volumetric measurements of bone grafts around dental implants. Three in vitro (one with a cylinder and two with a geometrically complex form) and four ex vivo mode...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-71651-1
更新日期:2020-09-10 00:00:00
abstract::Stored-product psocids (Psocoptera: Liposcelididae) are cosmopolitan storage pests that can damage stored products and cause serious economic loss. However, because of the body size (~1 mm) of eggs, nymphs, and adults, morphological identification of most stored-product psocids is difficult and hampers effective ident...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-16888-z
更新日期:2017-12-01 00:00:00
abstract::We have prepared and tested a new surface enhanced Raman scattering (SERS) substrate based on self-assembled graphitic sheets to detect bisphenol A (BPA) in plastic consumer goods. Transmission electron microscopy (TEM) and atomic-force microscopy (AFM) were used to characterize the structure of the graphitic sheets a...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-17030-9
更新日期:2017-12-01 00:00:00
abstract::The nuclear factor κB (NF-κB) pathway plays a key role in innate and adaptive immunity, cell proliferation and survival, inflammation and tumors development. MiR-146a is an immune system regulator that has anti-inflammatory function in multiple cell types and conditions. Here we demonstrate activation of canonical NF-...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-41530-5
更新日期:2019-03-26 00:00:00
abstract::The chemokine CCL3 is frequently overexpressed in malignancies and overexpression leads to microenvironmental dysfunction. In murine models of chronic myelogenous leukemia (CML), CCL3 is critical for the maintenance of a leukemia stem cell population, and leukemia progression. With CCL3 implicated as a potentially via...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-32978-y
更新日期:2018-10-02 00:00:00
abstract::The prion protein (PrPC), a mainly neuronal protein, is known to modulate glucose homeostasis in mouse models. We explored the underlying mechanism in mouse models and the human pancreatic β-cell line 1.1B4. We report expression of PrPC on mouse pancreatic β-cells, where it promoted uptake of iron through divalent-met...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-24786-1
更新日期:2018-04-26 00:00:00
abstract::Several studies have investigated the association between polymorphisms in protamine 1 and 2 genes and male infertility risk, with inconsistent results to date. This meta-analysis based on the 13 published case-control studies, including 7350 cases and 6167 controls, was performed to further establish the potential as...
journal_title:Scientific reports
pub_type: 杂志文章,meta分析
doi:10.1038/srep15300
更新日期:2015-10-16 00:00:00
abstract::The phylogenetic diversity of marine bacteria belonged to the Bacillus cereus group has not been well investigated. Here, we present the genetic diversity and population structure of 71 bacteria from diverse marine environments, using a multilocus sequence typing (MLST) approach and the analyses of digital DNA-DNA hyb...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-00817-1
更新日期:2017-04-06 00:00:00
abstract::The freshwater snail Oncomelania hupensis is the unique intermediate host of the blood fluke Schistosoma japonicum, which is the major cause of schistosomiasis. The snail inhabits two contrasting environments: the hilly and marshland regions. The hilly snails are smaller in size and have the typical smooth shell, wher...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-16084-z
更新日期:2017-11-17 00:00:00
abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title:Scientific reports
pub_type: 已发布勘误
doi:10.1038/s41598-020-58958-9
更新日期:2020-02-19 00:00:00
abstract::Heme catabolism exerts physiological functions that impact health through depressing inflammation. Upon reactive pathway progression, as in Gilbert's Syndrome (GS; UGT1A1*28 polymorphism), aggravated health effects have been determined. Based on lower inflammation and improved metabolic health reported for GS, inter-g...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-00933-y
更新日期:2017-04-07 00:00:00
abstract::Alternative oxidase (AOX) is a mitochondrial inner-membrane oxidase that accepts electrons directly from ubiquinol and reduces oxygen to water without involving cytochrome-linked electron transport chain. It is highly conserved in many non-vertebrate taxa and may protect cells against hypoxia and oxidative stress. We ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-10976-w
更新日期:2017-09-07 00:00:00
abstract::Alternative tillage and rice establishment options should aim at less water and labor to produce similar or improved yields compared with traditional puddled-transplanted rice cultivation. The relative performance of these practices in terms of yield, water input, and economics varies across rice-growing regions. A gl...
journal_title:Scientific reports
pub_type: 杂志文章,meta分析
doi:10.1038/s41598-017-09742-9
更新日期:2017-08-24 00:00:00
abstract::Bruton tyrosine kinase (BTK) is a key enzyme in B-cell development whose improper regulation causes severe immunodeficiency diseases. Design of selective BTK therapeutics would benefit from improved, in-silico structural modeling of the kinase's solution ensemble. However, this remains challenging due to the immense c...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-10697-0
更新日期:2017-11-15 00:00:00
abstract::A three-year-long field experiment was conducted in a continuous grazing system with a variable stocking rate to evaluate effects of increasing nitrogen levels in Marandu grass (Brachiaria brizantha Hochst ex A. Rich Stapf "marandu") on herbage mass, forage accumulation rate (FAR), forage quality, stocking rate (SR), ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-44138-x
更新日期:2019-05-20 00:00:00
abstract::Image enhancement techniques are able to improve the contrast and visual quality of magnetic resonance (MR) images. However, conventional methods cannot make up some deficiencies encountered by respective brain tumor MR imaging modes. In this paper, we propose an adaptive intuitionistic fuzzy sets-based scheme, called...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep35760
更新日期:2016-10-27 00:00:00
abstract::Stimuli presented at short temporal delays before functional magnetic resonance imaging (fMRI) can have a robust impact on the organization of synchronous activity in resting state networks. This presents an opportunity to investigate how sensory, affective and cognitive stimuli alter functional connectivity in rodent...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-76935-0
更新日期:2020-11-16 00:00:00
abstract::We report the experimental observation of energetically confined self-accelerating optical beams propagating along various convex trajectories. We show that, under an appropriate transverse compression of their spatial spectra, these self-accelerating beams can exhibit a dramatic enhancement of their peak intensity an...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep13197
更新日期:2015-08-24 00:00:00
abstract::This work describes a simple technique to produce porous ceramics with aligned porosity having very high permeability and specific surface area. SiOC-based compositions were processed from blends of three types of preceramic polymer and a catalyst, followed by curing and pyrolysis. The heating applied from the bottom ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep41049
更新日期:2017-01-20 00:00:00