Abstract：
:We hereby report for the first time on the design, manufacturing and testing of a three-dimensional (3D) nearly-periodic, locally resonant phononic crystal (PnC). Most of the research effort on PnCs and metamaterials has been focused on the enhanced dynamic properties arising from their periodic design. Lately, additive manufacturing techniques have made a number of designs with intrinsically complex geometries feasible to produce. These recent developments have led to innovative solutions for broadband vibration attenuation, with a multitude of potential engineering applications. The recently introduced concept of rainbow metamaterials and PnCs has shown a significant potential for further expanding the spectrum of vibration attenuation in such structures by introducing a gradient profile for the considered unit cells. Given the above, it is expected that designing non-periodic PnCs will attract significant attention from scientists and engineers in the years to come. The proposed nearly-periodic design is based on cuboid blocks connected by curved beams, with internal voids in the blocks being implemented to adjust the local masses and generate a 3D rainbow PnC. Results show that the proposed approach can produce lightweight PnCs of a simple, manufacturable design exhibiting attenuation bandwidths more than two times larger than the equivalent periodic designs of equal mass.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Meng H,Bailey N,Chen Y,Wang L,Ciampa F,Fabro A,Chronopoulos D,Elmadih Wdoi
10.1038/s41598-020-75977-8subject
Has Abstractpub_date
2020-11-04 00:00:00pages
18989issue
1issn
2045-2322pii
10.1038/s41598-020-75977-8journal_volume
10pub_type
杂志文章abstract：:LL37 exerts a dual pathogenic role in psoriasis. Bound to self-DNA/RNA, LL37 licenses autoreactivity by stimulating plasmacytoid dendritic cells-(pDCs)-Type I interferon (IFN-I) and acts as autoantigen for pathogenic Th17-cells. In systemic lupus erythematosus (SLE), LL37 also triggers IFN-I in pDCs and is target of p...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-62480-3
更新日期：2020-04-03 00:00:00
abstract：:Oil spills represent an overwhelming carbon input to the marine environment that immediately impacts the sea surface ecosystem. Microbial communities degrading the oil fraction that eventually sinks to the seafloor must also deal with hydrostatic pressure, which linearly increases with depth. Piezosensitive hydrocarbo...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep23526
更新日期：2016-03-29 00:00:00
abstract：:Species generalization in the profound, modality-specific effects of Hedgehog pathway inhibition (HPI) in taste organ homeostasis and sensation is shown. With the HPI, cancer drug sonidegib, we demonstrate that the rat taste system, in addition to mouse, is regulated by Hedgehog signaling. After sonidegib treatment fo...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-34399-3
更新日期：2018-11-01 00:00:00
abstract：:We organized a crowdsourcing experiment in the form of a snapshot sampling campaign to assess the spatial distribution of nitrogen solutes, namely, nitrate, ammonium and dissolved organic nitrogen (DON), in German surface waters. In particular, we investigated (i) whether crowdsourcing is a reasonable sampling method ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep16503
更新日期：2015-11-12 00:00:00
abstract：:Chlorophyll derivatives are known to enhance vision in vertebrates. They are thought to bind visual pigments (i.e., opsins apoproteins bound to retinal chromophores) directly within the retina. Consistent with previous findings in vertebrates, here we show that chlorin e6 - a chlorophyll derivative - enhances photopho...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-03247-1
更新日期：2017-06-13 00:00:00
abstract：:Although most models suggest continental Antarctica was covered by ice during the Last Glacial Maximum (LGM) it has been speculated that endemic species of soil invertebrates could have survived the Pleistocene at high elevation habitats protruding above the ice sheets. We analyzed a series of soil samples from differ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep26189
更新日期：2016-05-18 00:00:00
abstract：:The effect of the surface area of palm kernel shell activated carbon (PKSAC) on the properties of n-octadecane-encapsulated shape stabilized phase change material (SSPCM) for thermal energy storage (TES) application were studied. Various surface areas of the PKSAC were prepared using different amounts of H3PO4 treatme...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-72019-1
更新日期：2020-09-14 00:00:00
abstract：:This study aims to prepare, characterize and evaluate the pharmacokinetics of liposomal donepezil HCl (LDH) dispersed into thiolated chitosan hydrogel (TCH) in rabbits. Various hydrogels including TCH were prepared, and after characterization, TCH was selected for subsequent evaluations, due to the promising results. ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-46032-y
更新日期：2019-07-02 00:00:00
abstract：:Elevated prostaglandin E2 (PGE2) levels are observed in colorectal cancer (CRC) patients, and this increase is associated with poor prognosis. Increased synthesis of PGE2 in CRC has been shown to occur through COX-2-dependent mechanisms; however, loss of the PGE2-catabolizing enzyme, 15-hydroxyprostaglandin dehydrogen...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-41862-2
更新日期：2019-04-01 00:00:00
abstract：:Orexins are originally characterized as orexigenic hypothalamic neuropeptides in mammals. Subsequent studies found orexin to be expressed and perform pleiotropic functions in multiple tissues in mammals. In avian (non-mammalian) species, however, orexin seemed to not affect feeding behavior and its physiological roles...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-76329-2
更新日期：2020-11-05 00:00:00
abstract：:Probing the oligomeric state of abundant molecules, such as membrane proteins in intact cells, is essential, but has not been straightforward. We address this challenge with a simple counting strategy that is capable of reporting the oligomeric state of dense, membrane-bound protein complexes. It is based on single-mo...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep14072
更新日期：2015-09-11 00:00:00
abstract：:This study tested the hypothesis that acquired epileptogenesis is accompanied by DNA methylation changes independent of etiology. We investigated DNA methylation and gene expression in the hippocampal CA3/dentate gyrus fields at 3 months following epileptogenic injury in three experimental models of epilepsy: focal am...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep25668
更新日期：2016-05-09 00:00:00
abstract：:A novel NaAgMoO4 material with spinel-like structure was synthesized by using the solid state reaction method and the ceramic sample was well densified at an extreme low sintering temperature about 400°C. Rietveld refinement of the crystal structure was performed using FULLPROF program and the cell parameters are a = ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep05980
更新日期：2014-08-07 00:00:00
abstract：:Irreversible electroporation (IRE) is a non-thermal ablation modality that has been shown to be safe and effective in its application to tumors that are close to risky areas. This study aims to assess the safety and efficacy of IRE for unresectable hilar cholangiocarcinoma. Nine patients from two medical centers in As...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-67772-2
更新日期：2020-07-02 00:00:00
abstract：:In 2010, a new rabbit hemorrhagic disease virus (RHDV) variant, designated RHDV2, was identified for the first time in Italy. Studies have shown that RHDV2 differs from RHDV1 (traditional RHDV) in terms of its antigenic profile and genetic characteristics. The VP60 protein of RHDV is a structural protein that plays im...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep20857
更新日期：2016-02-16 00:00:00
abstract：:Lung adenocarcinoma (LUAD) is characterized by high infiltration and rapid growth. The function of the stem cell population is to control and maintain cell regeneration. Therefore, it is necessary to study the prognostic value of stem cell-related genes in LUAD. Signature genes were screened out from 166 stem cell-rel...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-80453-4
更新日期：2021-01-18 00:00:00
abstract：:Evasion of the potent tumour suppressor activity of p53 is one of the hurdles that must be overcome for cancer cells to escape normal regulation of cellular proliferation and survival. In addition to frequent loss of function mutations, p53 wild-type activity can also be suppressed post-translationally through several...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-28002-y
更新日期：2018-06-26 00:00:00
abstract：:The cell adhesion molecule Cadherin 2 (Cdh2) plays important roles in somatic cell adhesion, proliferation and migration. Cdh2 is also highly expressed in mouse epiblast stem cells (mEpiSCs), but its function in these cells is unknown. To understand the function of Cdh2 in mEpiSCs, we compared the expression of plurip...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep14722
更新日期：2015-09-30 00:00:00
abstract：:Melon (Cucumis melo L.) is a very important crop throughout the world and has great economic importance, in part due to its nutritional properties. It prefers well-drained soil with low acidity and has a strong demand for water during fruit set. Therefore, a correct water balance-involving aquaporins-is necessary to m...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-79250-w
更新日期：2020-12-17 00:00:00
abstract：:Macrophages play a crucial role in the control and elimination of invading Mycobacterium tuberculosis (Mtb), and also serve as the major residence for Mtb. However, the interaction between macrophages and Mtb remains to be clearly determined. Although long noncoding RNAs (lncRNAs) have emerged as key regulators in man...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep38963
更新日期：2016-12-14 00:00:00
abstract：:The epithelial-to-mesenchymal transition (EMT) is one of mechanisms that induce renal interstitial fibrosis. Understanding EMT in renal fibrosis has important therapeutic implications for patients with kidney disease. Alpha-lipoic acid (ALA) is a natural compound with antioxidant properties. Studies for ALA are perfor...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep46065
更新日期：2017-04-05 00:00:00
abstract：:FGF10 is a member of fibroblast growth factors (FGFs). We previously showed that FGF10 protects neuron against oxygen-glucose deprivation injury in vitro; however, the effect of FGF10 in ischemic stroke in vivo is unknown. In the present study, we showed that FGF10 was mainly expressed in neurons but not astrocytes, a...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep19869
更新日期：2016-01-27 00:00:00
abstract：:GlgE, an enzyme of the pathway that converts trehalose to α-glucans, is essential for Mycobacterium tuberculosis. Inhibition of GlgE, which transfers maltose from a maltose-1-phosphate donor to α-glucan/maltooligosaccharide chain acceptor, leads to a toxic accumulation of maltose-1-phosphate that culminates in cellula...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep17144
更新日期：2015-11-30 00:00:00
abstract：:The ovules and egg cells are well developed to be fertilized at anthesis in many flowering plants. However, ovule development is triggered by pollination in most orchids. In this study, we characterized the function of a Bsister gene, named PeMADS28, isolated from Phalaenopsis equestris, the genome-sequenced orchid. S...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-79877-9
更新日期：2021-01-13 00:00:00
abstract：:Electrostatic gates are of paramount importance for the physics of devices based on high-mobility two-dimensional electron gas (2DEG) since they allow depletion of electrons in selected areas. This field-effect gating enables the fabrication of a wide range of devices such as, for example, quantum point contacts (QPC)...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep13494
更新日期：2015-09-22 00:00:00
abstract：:Understanding how animals respond to injury and how wounds heal remains a challenge. These questions can be addressed using genetically tractable animals, including the nematode Caenorhabditis elegans. Given its small size, the current methods for inflicting wounds in a controlled manner are demanding. To facilitate a...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-60333-7
更新日期：2020-02-27 00:00:00
abstract：:The intercellular spreading of protein assemblies is a major factor in the progression of neurodegenerative disorders. The quantitative study and visualization of cell-to-cell propagation using tagged-proteins is challenging due to the steric effect of relatively large fluorescence tags and the risk of 'false positive...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-00657-z
更新日期：2017-03-28 00:00:00
abstract：:We report the new insight into the dielectric barrier discharge (DBD) induced inactivation of Microcystis aeruginosa, the dominant algae which caused harmful cyanobacterial blooms in many developing countries. In contrast with the previous work, we employed flow cytometry to examine the algal cells, so that we could a...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep13683
更新日期：2015-09-08 00:00:00
abstract：:Surface-enhanced Raman scattering (SERS) can significantly boost the inherently weak Raman scattering signal and provide detailed structural information and binding nature of the molecules on the surface. Despite the long history of this technology, SERS has yet to become a sophisticated analytical tool in practical a...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep17167
更新日期：2015-11-30 00:00:00
abstract：:Behavioral addiction (BA) is characterized by repeated, impulsive and compulsive seeking of specific behaviors, even with consequent negative outcomes. In drug addiction, alterations in biological mechanisms, such as monoamines and epigenetic processes, have been suggested, whereas whether such mechanisms are also alt...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-68741-5
更新日期：2020-07-16 00:00:00
