Mobile phone imaging and cloud-based analysis for standardized malaria detection and reporting.

abstract：:We report the molecular basis of the largest Tunisian cohort with inherited retinal dystrophies (IRD) reported to date, identify disease-causing pathogenic variants and describe genotype-phenotype correlations. A subset of 26 families from a cohort of 73 families with clinical diagnosis of autosomal recessive IRD (AR-...

journal_title：Scientific reports

authors： Habibi I,Falfoul Y,Turki A,Hassairi A,El Matri K,Chebil A,Schorderet DF,El Matri L

更新日期：2020-07-08 00:00:00

abstract：:Most of the human genome is non-coding. However, some of the non-coding part is transcriptionally active. In humans, the tandemly repeated (TR) pericentromeric non-coding DNA-human satellites 2 and 3 (HS2, HS3)-are transcribed in somatic cells. These transcripts are also found in pre- and post-implantation embryos. Th...

journal_title：Scientific reports

authors： Dobrynin MA,Korchagina NM,Prjibelski AD,Shafranskaya D,Ostromyshenskii DI,Shunkina K,Stepanova I,Kotova AV,Podgornaya OI,Enukashvily NI

更新日期：2020-11-12 00:00:00

abstract：:Slow disintegration and poor solubility are common problems facing the dispersible tablets of Traditional Chinese Medicine (TCM). In an early study, the research group found that co-grinding of extracts and silica could achieve a rapid disintegration effect, though the mechanism of this effect was not thoroughly eluci...

journal_title：Scientific reports

authors： Li P,Feng B,Jiang H,Han X,Wu Z,Wang Y,Lin J,Zhang Y,Yang M,Han L,Zhang D

更新日期：2018-07-09 00:00:00

abstract：:The preparation of mesoporous iron oxides with controllable physiochemical properties for effective therapeutic drug delivery remains a formidable challenge. Herein, iron oxide mesoporous magnetic microparticles (IO-MMMs) were prepared by a modified reverse hard-templating approach using, for the first time, acid-prep...

journal_title：Scientific reports

authors： El-Boubbou K,Ali R,Al-Zahrani H,Trivilegio T,Alanazi AH,Khan AL,Boudjelal M,AlKushi A

更新日期：2019-07-01 00:00:00

abstract：:This study was aimed to investigate the prognostic value of neutrophil-to-lymphocyte ratio (NLR) in patients with prostate cancer (PCa). A meta-analysis including 14 publications (15 cohorts) with 16,266 patients was performed to evaluate the association between NLR and overall survival (OS), progression-free survival...

journal_title：Scientific reports

authors： Gu X,Gao X,Li X,Qi X,Ma M,Qin S,Yu H,Sun S,Zhou D,Wang W

更新日期：2016-02-25 00:00:00

abstract：:An atmospheric component of the Philippine-Taiwan Oscillations (PTOa) is used to examine its potential connection with tropical cyclone (TC) frequency in the western North Pacific in the period of 1979-2014. During positive PTOa years, more TCs are observed in the tropical western Pacific south of 18 °N where cyclonic...

journal_title：Scientific reports

authors： Chang YK,Miyazawa Y,Kodaira T,Behera S

更新日期：2018-11-29 00:00:00

abstract：:Maize is rapidly replacing traditionally cultivated dual purpose crops of South Asia, primarily due to the better economic remuneration. This has created an impetus for improving maize for both grain productivity and stover traits. Molecular techniques can largely assist breeders in determining approaches for effectiv...

journal_title：Scientific reports

authors： Vinayan MT,Seetharam K,Babu R,Zaidi PH,Blummel M,Nair SK

更新日期：2021-01-12 00:00:00

abstract：:Collagen XVII and integrin α6β4 have well-established roles as epithelial adhesion molecules. Their binding partner laminin 332 as well as integrin α6β4 are largely recognized to promote invasion and metastasis in various cancers, and collagen XVII is essential for the survival of colon and lung cancer stem cells. We ...

journal_title：Scientific reports

authors： Moilanen JM,Löffek S,Kokkonen N,Salo S,Väyrynen JP,Hurskainen T,Manninen A,Riihilä P,Heljasvaara R,Franzke CW,Kähäri VM,Salo T,Mäkinen MJ,Tasanen K

更新日期：2017-03-22 00:00:00

abstract：:Entamoeba possesses a highly divergent mitochondrion-related organelle known as the mitosome. Here, we report the discovery of a novel protein in Entamoeba, which we name Mitosomal β-barrel Outer Membrane Protein of 30 kDa (MBOMP30). Initially identified through in silico analysis, we experimentally confirmed that MBO...

journal_title：Scientific reports

authors： Santos HJ,Imai K,Makiuchi T,Tomii K,Horton P,Nozawa A,Ibrahim M,Tozawa Y,Nozaki T

更新日期：2015-02-25 00:00:00

abstract：:The centrosome is the microtubule organizing center of human cells and facilitates a myriad of cellular functions including organization of the mitotic spindle to ensure faithful chromosome segregation during mitosis, cell polarization and migration, and primary cilia formation. A numerical increase in centrosomes, or...

journal_title：Scientific reports

authors： Denu RA,Burkard ME

更新日期：2020-07-17 00:00:00

abstract：:The aim of this study was to estimate the influence of regenerated tobacco on the extraction of Cd from two acidic soils as well as to address the problem of how to deal with contaminated leaves following phytoextraction. Results showed that a coppicing tobacco led to a decline in Cd concentration in regenerated leave...

journal_title：Scientific reports

authors： Yang Y,Ge Y,Zeng H,Zhou X,Peng L,Zeng Q

更新日期：2017-08-03 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Kim KH,Lara-Avila S,Kang H,He H,Eklӧf J,Hong SJ,Park M,Moth-Poulsen K,Matsushita S,Akagi K,Kubatkin S,Park YW

更新日期：2020-04-10 00:00:00

abstract：:Two embedded sulfur atoms in a novel [2 + 2] Schiff-base macrocyclic dinuclear Zn(II) complex were found to be easily autoxidized to the sulfone units on air exposure, and the resultant sulfone-functionalized macrocyclic complex was obtained by the post-modification strategy exhibiting enhanced antimicrobial activitie...

journal_title：Scientific reports

authors： Feng G,Shi Y,Zhang L,Shi R,Huang W,Wang R

更新日期：2017-11-21 00:00:00

abstract：:A variety of environmental factors contribute to progressive development of osteoarthritis (OA). Environmental factors that upset circadian rhythms have been linked to various diseases. Our recent work establishes chronic environmental circadian disruption - analogous to rotating shiftwork-associated disruption of cir...

journal_title：Scientific reports

authors： Kc R,Li X,Forsyth CB,Voigt RM,Summa KC,Vitaterna MH,Tryniszewska B,Keshavarzian A,Turek FW,Meng QJ,Im HJ

更新日期：2015-11-20 00:00:00

abstract：:We studied the spin-transfer torque (STT) in graphene based normal-metal/topological-insulator/ferromagnet heterostructures (N/TI/F), which is induced by the helical spin-polarized current in the quantum spin Hall insulator. We found that the STT is comparable in magnitude to the STT in ferromagnetic-normal- ferromagn...

journal_title：Scientific reports

authors： Zhang Q,Chan KS,Li J

更新日期：2018-03-12 00:00:00

abstract：:Endothelial cells are spatially close to osteoblasts and regulate osteogenesis. Moreover, they are sensitive to mechanical stimuli, therefore we hypothesized that they are implicated in the regulation of bone metabolism during unloading. Conditioned media from endothelial cells (EC-CM) subjected to simulated micrograv...

journal_title：Scientific reports

authors： Veeriah V,Zanniti A,Paone R,Chatterjee S,Rucci N,Teti A,Capulli M

更新日期：2016-07-19 00:00:00

abstract：:Increased ultraviolet B (UVB) radiation due to global change can affect plant growth and metabolism. Here, we evaluated the capacity of quinoa to resist under short acute UVB irradiation. Quinoa was daily exposed for 30 or 60 min to 1.69 W m-2 UVB. The results showed that 30 min exposure in 9 d-course did not cause se...

journal_title：Scientific reports

authors： Huarancca Reyes T,Scartazza A,Castagna A,Cosio EG,Ranieri A,Guglielminetti L

更新日期：2018-01-10 00:00:00

abstract：:Oral microbiome dysbiosis has been associated with various local and systemic human diseases such as dental caries, periodontal disease, obesity, and cardiovascular disease. Bacterial composition may be affected by age, oral health, diet, and geography, although information about the natural variation found in the gen...

journal_title：Scientific reports

authors： Burcham ZM,Garneau NL,Comstock SS,Tucker RM,Knight R,Metcalf JL,Genetics of Taste Lab Citizen Scientists.

更新日期：2020-02-07 00:00:00

abstract：:Attraction to infants is a common feature of non-human primates. Frequent affiliative male-infant interactions have been observed in many multimale, multifemale groups of macaques, including a behaviour termed 'bridging' in which two male macaques simultaneously lift an infant. This behaviour has been suggested to ser...

journal_title：Scientific reports

authors： Zhang D,Xia DP,Wang X,Zhang QX,Sun BH,Li JH

更新日期：2018-11-02 00:00:00

abstract：:Fiber shaped supercapacitors are promising candidates for wearable electronics because they are flexible and light-weight. However, a critical challenge of the widespread application of these energy storage devices is their low cell voltages and low energy densities, resulting in limited run-time of the electronics. H...

journal_title：Scientific reports

authors： Cai W,Lai T,Lai J,Xie H,Ouyang L,Ye J,Yu C

更新日期：2016-06-01 00:00:00

abstract：:A major challenge in nanofabrication is to pattern unconventional substrates that cannot be processed for a variety of reasons, such as incompatibility with spin coating, electron beam lithography, optical lithography, or wet chemical steps. Here, we present a versatile nanofabrication method based on re-usable silico...

journal_title：Scientific reports

authors： Li L,Bayn I,Lu M,Nam CY,Schröder T,Stein A,Harris NC,Englund D

更新日期：2015-01-15 00:00:00

abstract：:There is an increasing appreciation for the role of the human Y chromosome in phenotypic differences between the sexes in health and disease. Previous studies have shown that genetic variation within the Y chromosome is associated with cholesterol levels, which is an established risk factor for atherosclerosis, the un...

journal_title：Scientific reports

authors： Molina E,Chew GS,Myers SA,Clarence EM,Eales JM,Tomaszewski M,Charchar FJ

更新日期：2017-12-01 00:00:00

abstract：:The expression of legumain which has been shown overexpressed in patients with metastatic gastric cancer is positively correlated to both disease progression and outcome, and negatively correlated to microRNA (miR)-3978 expression. The RNA-binding protein, poly r(C) binding protein 1 (PCBP1) was the most downregulated...

journal_title：Scientific reports

authors： Ji FJ,Wu YY,An Z,Liu XS,Jiang JN,Chen FF,Fang XD

更新日期：2017-11-14 00:00:00

abstract：:We have developed an optimized protocol for plasma targeted mRNA sequencing in our previous study. Here, we performed plasma targeted mRNA sequencing for 40 colorectal adenoma patients and 39 colonoscopy-proven normal controls in order to find potential circulating mRNA markers for colorectal adenoma. Results showed t...

journal_title：Scientific reports

authors： Xue VW,Cheung MT,Chan PT,Luk LLY,Lee VH,Au TC,Yu AC,Cho WCS,Tsang HFA,Chan AK,Wong SCC

更新日期：2019-09-10 00:00:00

abstract：:Iron oxide nanoparticles (IONPs) are known to induce cytotoxicity in various cancer cell lines through the generation of reactive oxygen species (ROS). However, the studies on its potential to induce toxicity in normal cell lines and in vivo system are limited and ambiguity still exists. Additionally, small molecules ...

journal_title：Scientific reports

authors： Ansari MO,Parveen N,Ahmad MF,Wani AL,Afrin S,Rahman Y,Jameel S,Khan YA,Siddique HR,Tabish M,Shadab GGHA

更新日期：2019-05-06 00:00:00

abstract：:Liver repopulation by transplanted hepatocytes has not been achieved previously in a normal liver microenvironment. Here we report that adult rat hepatocytes transduced ex vivo with a lentivirus expressing a human YapERT2 fusion protein (hYapERT2) under control of the hepatocyte-specific transthyretin (TTR) promoter r...

journal_title：Scientific reports

authors： Yovchev M,Jaber FL,Lu Z,Patel S,Locker J,Rogler LE,Murray JW,Sudol M,Dabeva MD,Zhu L,Shafritz DA

更新日期：2016-01-14 00:00:00

abstract：:Technological advances have made it possible to examine dental resin composites using 3D nanometer resolution. This investigation aims to characterize existing dental nano-hybrid and micro-hybrid resin composites through comparing and contrasting nano-computed tomography (nano-CT) with micro-CT and high-resolution SEM...

journal_title：Scientific reports

authors： Haugen HJ,Qasim SB,Matinlinna JP,Vallittu P,Nogueira LP

更新日期：2020-09-23 00:00:00

abstract：:In spite of its prevalence in animals and plants, endogenous nitric oxide (NO) has been rarely reported in fungi. We present here our observations on production of intracellular NO and its possible roles during development of Neurospora crassa, a model filamentous fungus. Intracellular NO was detected in hypha 8-16 ho...

journal_title：Scientific reports

authors： Pengkit A,Jeon SS,Son SJ,Shin JH,Baik KY,Choi EH,Park G

更新日期：2016-07-18 00:00:00

abstract：:Distillers grains are co-products of the corn ethanol industry widely used in animal feed. We examined the effects of erythromycin, penicillin, and virginiamycin at low concentrations reflective of those detected in distillers grains on bacterial resistance selection. At 0.1 µg/ml erythromycin, macrolide-resistant mut...

journal_title：Scientific reports

authors： Ge B,Domesle KJ,Yang Q,Young SR,Rice-Trujillo CL,Bodeis Jones SM,Gaines SA,Keller MW,Li X,Piñeiro SA,Whitney BM,Harbottle HC,Gilbert JM

更新日期：2017-09-08 00:00:00

abstract：:Visual evoked potential-based brain-computer interfaces (BCIs) have been widely investigated because of their easy system configuration and high information transfer rate (ITR). However, the uncomfortable flicker or brightness modulation of existing methods restricts the practical interactivity of BCI applications. In...

journal_title：Scientific reports

authors： Han C,Xu G,Xie J,Chen C,Zhang S

更新日期：2018-04-11 00:00:00