Bridging may help young female Tibetan macaques Macaca thibetana learn to be a mother.

abstract：:Complex networks characterize the nature of internal/external interactions in real-world systems including social, economic, biological, ecological, and technological networks. Two issues keep as obstacles to fulfilling control of large-scale networks: structural controllability which describes the ability to guide a ...

journal_title：Scientific reports

authors： Li G,Deng L,Xiao G,Tang P,Wen C,Hu W,Pei J,Shi L,Stanley HE

更新日期：2018-03-15 00:00:00

abstract：:Magnolia sirindhorniae Noot. & Chalermglin is an endangered species with high ornamental and commercial value that needs to be urgently protected and judiciously commercialized. In this study, a protocol for efficient regeneration of this species is standardized. The lateral buds of the M. sirindhorniae plant were use...

journal_title：Scientific reports

authors： Cui Y,Deng Y,Zheng K,Hu X,Zhu M,Deng X,Xi R

更新日期：2019-07-03 00:00:00

abstract：:Despite the frequent use of ionising radiation (IR) in therapy and diagnostics and the unavoidable exposure to external radiation sources, our knowledge regarding the radiosensitivity of human blood cell populations is limited and published data, obtained under different experimental conditions, are heterogeneous. To ...

journal_title：Scientific reports

authors： Heylmann D,Ponath V,Kindler T,Kaina B

更新日期：2021-01-28 00:00:00

abstract：:Unimolecular dual agonists for the glucagon-like peptide 1 receptor (GLP1R) and glucagon receptor (GCGR) are emerging as a potential new class of important therapeutics in type 2 diabetes (T2D). Reliable and quantitative assessments of in vivo occupancy on each receptor would improve the understanding of the efficacy ...

journal_title：Scientific reports

authors： Eriksson O,Haack T,Hijazi Y,Teichert L,Tavernier V,Laitinen I,Berglund JE,Antoni G,Velikyan I,Johansson L,Pierrou S,Wagner M,Tillner J

更新日期：2020-10-07 00:00:00

abstract：:Improving the affinity of protein-protein interactions is a challenging problem that is particularly important in the development of antibodies for diagnostic and clinical use. Here, we used structure-based computational methods to optimize the binding affinity of VHNAC1, a single-domain intracellular antibody (intrab...

journal_title：Scientific reports

authors： Mahajan SP,Meksiriporn B,Waraho-Zhmayev D,Weyant KB,Kocer I,Butler DC,Messer A,Escobedo FA,DeLisa MP

更新日期：2018-12-04 00:00:00

abstract：:E. coli expressed recombinant basic fibroblast growth factor (bFGF) with histidine-tag (bFGF-His) was immobilized onto the surface of a glass plate modified with a Ni(II)-chelated alkanethiol monolayer. The immobilization is expected to take place through the coordination between Ni(II) and His-tag. The bFGF-immobiliz...

journal_title：Scientific reports

authors： Shakya A,Imado E,Nguyen PK,Matsuyama T,Horimoto K,Hirata I,Kato K

更新日期：2020-05-29 00:00:00

abstract：:The pollination syndrome concept has provided powerful utility in understanding the evolution and adaptation of floral traits. However, the utility of this conception has been questioned on the grounds that flowers usually attract a broader spectrum of visitors than one might expect. Furthermore, the relationship betw...

journal_title：Scientific reports

authors： Wang X,Wen M,Qian X,Pei N,Zhang D

更新日期：2020-08-18 00:00:00

abstract：:Recent genome-wide association studies (GWAS) of Parkinson's disease (PD) revealed at least 26 risk loci, with associated single nucleotide polymorphisms (SNPs) located in non-coding DNA having unknown functions in risk. In order to explore in which cell types these SNPs (and their correlated surrogates at r(2) ≥ 0.8)...

journal_title：Scientific reports

authors： Coetzee SG,Pierce S,Brundin P,Brundin L,Hazelett DJ,Coetzee GA

更新日期：2016-07-27 00:00:00

abstract：:Carcinomas constitute over 80% of all human cancer types with no effective therapy for metastatic disease. Here, we demonstrate, for the first time, the efficacy of therapeutic-ultrasound (TUS) to deliver a human tumor suppressor gene, hSef-b, to prostate tumors in vivo. Sef is downregulated in various human carcinoma...

journal_title：Scientific reports

authors： Mishel S,Shneyer B,Korsensky L,Goldshmidt-Tran O,Haber T,Machluf M,Ron D

更新日期：2017-11-08 00:00:00

abstract：:It is essential to understand how the loss of biodiversity impacts both ecosystem function (EF) and multifunctionality (EMF). Previous studies have mostly focused on predicting how species richness (SR) impacts EMF, while the effect of functional diversity (FD) on EMF remains unclear. Specifically, we know little abou...

journal_title：Scientific reports

authors： Huang X,Su J,Li S,Liu W,Lang X

更新日期：2019-05-06 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Sharman GR,Sylvester Z,Covault JA

更新日期：2020-11-02 00:00:00

abstract：:Automated vehicles (AVs) will change the role of the driver, from actively controlling the vehicle to primarily monitoring it. Removing the driver from the control loop could fundamentally change the way that drivers sample visual information from the scene, and in particular, alter the gaze patterns generated when un...

journal_title：Scientific reports

authors： Mole C,Pekkanen J,Sheppard WEA,Markkula G,Wilkie RM

更新日期：2021-01-08 00:00:00

abstract：:In this study, we have employed graphene oxide as a matrix to simultaneously and directly quantify serum nonesterified and esterified fatty acids (FAs) using matrix-assisted laser/desorption ionization-Fourier transform ion cyclotron resonance mass spectrometry (MALDI-FTICR MS). Twelve serum nonesterified FAs combined...

journal_title：Scientific reports

authors： Ren J,Zhang D,Liu Y,Zhang R,Fang H,Guo S,Zhou D,Zhang M,Xu Y,Qiu L,Li Z

更新日期：2016-09-30 00:00:00

abstract：:Paedomorphosis and metamorphosis are two major developmental processes that characterize the evolution of complex life cycles in many lineages. Whereas these processes were fixed in some taxa, they remained facultative in others, with alternative phenotypes expressed in the same populations. From a genetic perspective...

journal_title：Scientific reports

authors： Oromi N,Michaux J,Denoël M

更新日期：2016-08-18 00:00:00

abstract：:Dysregulation in cytokine production has been linked to the pathogenesis of various immune-mediated traits, in which genetic variability contributes to the etiopathogenesis. GWA studies have identified many genetic variants in or near cytokine genes, nonetheless, the translation of these findings into knowledge of fun...

journal_title：Scientific reports

authors： Salnikova LE,Khadzhieva MB,Kolobkov DS,Gracheva AS,Kuzovlev AN,Abilev SK

更新日期：2020-09-07 00:00:00

abstract：:Enterococci are nosocomial pathogens that can form biofilms, which contribute to their virulence and antibiotic resistance. Although many genes involved in biofilm formation have been defined, their distribution among enterococci has not been comprehensively studied on a genome scale, and their diagnostic ability to p...

journal_title：Scientific reports

authors： Hashem YA,Amin HM,Essam TM,Yassin AS,Aziz RK

更新日期：2017-07-18 00:00:00

abstract：:Tractography atlas-based analysis (TABS) is a new diffusion tensor image (DTI) statistical analysis method for detecting and understanding voxel-wise white matter properties along a fiber tract. An important requisite for accurate and sensitive TABS is the availability of a deformation field that is able to register D...

journal_title：Scientific reports

authors： Mu J,Xu Q,Tian J,Liu J

更新日期：2017-10-04 00:00:00

abstract：:There is significant interest in understanding the pathophysiology of Obsessive-Compulsive Disorder (OCD) using resting-state fMRI (rsfMRI). Previous studies acknowledge abnormalities within and beyond the fronto-striato-limbic circuit in OCD that require further clarifications. However, limited information could be i...

journal_title：Scientific reports

authors： Kashyap R,Eng GK,Bhattacharjee S,Gupta B,Ho R,Ho CSH,Zhang M,Mahendran R,Sim K,Chen SHA

更新日期：2021-01-14 00:00:00

abstract：:Childhood obesity and early rapid growth increase the risk for type 2 diabetes. Such early overnutrition can be modeled in mice by reducing litter size. We investigated the effects of early overnutrition and increased dietary fat intake on β cell function in Swiss Webster mice. On a moderate-fat diet, early overnutrit...

journal_title：Scientific reports

authors： Glavas MM,Hui Q,Tudurí E,Erener S,Kasteel NL,Johnson JD,Kieffer TJ

更新日期：2019-03-06 00:00:00

abstract：:Cardiotrophin-1 is known to be a key regulator of energy homeostasis, as well as glucose and lipid metabolism in vivo. However, there are inconsistent results of the association between cardiotrophin-1 and obesity in humans, possibly confounded by hyperglycemia. Therefore, the aim of this study was to investigate the ...

journal_title：Scientific reports

authors： Hung HC,Lu FH,Wu HT,Ou HY,Yang YC,Wu JS,Chang CJ

更新日期：2015-12-01 00:00:00

abstract：:The structure of metallic glasses is a long-standing question because the lack of long-range order makes diffraction based techniques difficult to be applied. Here, we used scanning tunneling microscopy with large tunneling resistance of 6 GΩ at low temperature in order to minimize forces between probe and sample and ...

journal_title：Scientific reports

authors： Pawlak R,Marot L,Sadeghi A,Kawai S,Glatzel T,Reimann P,Goedecker S,Güntherodt HJ,Meyer E

更新日期：2015-08-13 00:00:00

abstract：:Saponins from defatted root-extract of Securidaca longipedunculata were systematically entrapped in emulsion monolayer-barrier and finally recovered in pure form through demulsification. First, their molecules were dispersed in water to engineer a monomolecular film architecture, via self-assembly. Emulsifying with et...

journal_title：Scientific reports

authors： Obasi TC,Moldovan R,Toiu A,Braicu C,Bodoki E,Berindan-Neagoe I,Oniga I,Sandulescu R,Oprean R

更新日期：2017-11-06 00:00:00

abstract：:Experiments on the Ultimatum Game (UG) repeatedly show that people's behaviour is far from rational. In UG experiments, a subject proposes how to divide a pot and the other can accept or reject the proposal, in which case both lose everything. While rational people would offer and accept the minimum possible amount, i...

journal_title：Scientific reports

authors： Han X,Cao S,Bao JZ,Wang WX,Zhang B,Gao ZY,Sánchez A

更新日期：2018-01-19 00:00:00

abstract：:Extensive mapping of neuronal connections in the central nervous system requires high-throughput µm-scale imaging of large volumes. In recent years, different approaches have been developed to overcome the limitations due to tissue light scattering. These methods are generally developed to improve the performance of a...

journal_title：Scientific reports

authors： Costantini I,Ghobril JP,Di Giovanna AP,Allegra Mascaro AL,Silvestri L,Müllenbroich MC,Onofri L,Conti V,Vanzi F,Sacconi L,Guerrini R,Markram H,Iannello G,Pavone FS

更新日期：2015-05-07 00:00:00

abstract：:Predation has driven the evolution of diverse adaptations for defence among prey, and one striking example is the deimatic display. While such displays can resemble, or indeed co-occur with, aposematic 'warning' signals, theory suggests deimatic displays may function independently of predator learning. The survival va...

journal_title：Scientific reports

authors： Umbers KDL,White TE,De Bona S,Haff T,Ryeland J,Drinkwater E,Mappes J

更新日期：2019-01-24 00:00:00

abstract：:The growing prevalence of resistance to antibiotics motivates the search for new antibacterial agents. Antimicrobial peptides are a diverse class of well-studied membrane-active peptides which function as part of the innate host defence system, and form a promising avenue in antibiotic drug research. Some antimicrobia...

journal_title：Scientific reports

authors： Timmons PB,Hewage CM

更新日期：2020-07-02 00:00:00

abstract：:The objective of our study is to highlight the therapeutic effect and mechanism of action by which purified Flaxseed hydrolysate (PFH) which is a lignan rich fraction exerts its anticancer activity on a human breast cancer cell line (T47D) and in mice bearing tumor. HPLC analysis of PFH of six flaxseed cultivars had s...

journal_title：Scientific reports

authors： Ezzat SM,Shouman SA,Elkhoely A,Attia YM,Elsesy MS,El Senousy AS,Choucry MA,El Gayed SH,El Sayed AA,Sattar EA,El Tanbouly N

更新日期：2018-01-11 00:00:00

abstract：:It is known that ribosomal RNA (rRNA) synthesis is regulated by cellular energy and proliferation status. In this study, we investigated rRNA gene transcription in response to cytoskeletal stress. Our data revealed that the cell shape constrained by isotropic but not elongated micropatterns in HeLa cells led to a sign...

journal_title：Scientific reports

authors： Wu TH,Kuo YY,Lee HH,Kuo JC,Ou MH,Chang ZF

更新日期：2016-06-28 00:00:00

abstract：:Optical antennas can be used to manipulate the direction and polarization of radiation from an emitter. Usually, these metallic nanostructures utilize localized plasmon resonances to generate highly directional and strongly polarized emission, which is determined predominantly by the antenna geometry alone, and is thu...

journal_title：Scientific reports

authors： Ghimire A,Shafran E,Gerton JM

更新日期：2014-09-24 00:00:00

abstract：:Combination targeted therapy is commonly used to treat acute myeloid leukemia (AML) patients, particularly in refractory/relapse (RR) population. However, concerns have been raised regarding the safety and patient tolerance of combination chemotherapy. It is critical to choose the appropriate treatment for precision t...

journal_title：Scientific reports

authors： Liang H,Zheng QL,Fang P,Zhang J,Zhang T,Liu W,Guo M,Robinson CL,Chen SB,Chen XP,Chen FP,Zeng H

更新日期：2017-01-18 00:00:00