A Novel Forming Method of Traditional Chinese Medicine Dispersible Tablets to Achieve Rapid Disintegration Based on the Powder Modification Principle.

abstract：:In clinical translational research and molecular in vitro diagnostics, a major challenge in the detection of genetic mutations is overcoming artefactual results caused by the low-quality of formalin-fixed paraffin-embedded tissue (FFPET)-derived DNA (FFPET-DNA). Here, we propose the use of an 'internal quality control...

journal_title：Scientific reports

authors： Kim SS,Choi HJ,Kim JJ,Kim MS,Lee IS,Byun B,Jia L,Oh MR,Moon Y,Park S,Choi JS,Chae SW,Nam BH,Kim JS,Kim J,Min BS,Lee JS,Won JK,Cho SY,Choi YL,Shin YK

更新日期：2018-01-11 00:00:00

abstract：:Soil physical properties and soil organic carbon (SOC) are considered as important factors of soil quality. Arable land, grassland, and forest land coexist in the saline-alkali reclamation area of the Yellow River Delta (YRD), China. Such different land uses strongly influence the services of ecosystem to induce soil ...

journal_title：Scientific reports

authors： Jiao S,Li J,Li Y,Xu Z,Kong B,Li Y,Shen Y

更新日期：2020-11-23 00:00:00

abstract：:Isolating actively proliferating cardioblasts is the first crucial step for cardiac regeneration through cell implantation. However, the origin and identity of putative cardioblasts are still unclear. Here, we uncover a novel class of cardiac lineage cells, PDGFRα+Flk1- cardioblasts (PCBs), from mouse and human plurip...

journal_title：Scientific reports

authors： Hong SP,Song S,Cho SW,Lee S,Koh BI,Bae H,Kim KH,Park JS,Do HS,Im I,Heo HJ,Ko TH,Park JH,Youm JB,Kim SJ,Kim I,Han J,Han YM,Koh GY

更新日期：2017-02-06 00:00:00

abstract：:Tobacco smoking is the major cause of many chronic diseases, especially lung cancer. Knowledge about population-wide tobacco use and exposure is essential to characterise its burden on public health and evaluate policy efficacy. Obtaining such knowledge remains challenging with current methods (e.g., surveys, biomonit...

journal_title：Scientific reports

authors： Lai FY,Lympousi K,Been F,Benaglia L,Udrisard R,Delémont O,Esseiva P,Thomaidis NS,Covaci A,van Nuijs ALN

更新日期：2018-09-05 00:00:00

abstract：:A layered nanoreactor (zinc hydroxide gallate/nitrate nanohybrid) has been designed as a nano-vessel to confine the gallate/nitrate reaction inside zinc hydroxide layers for production of metal/nitrogen-doped carbon catalysts. Metals (Fe2+, Co2+ and Ni2+) doped and bare zinc hydroxide nitrates (ZHN) were synthesized a...

journal_title：Scientific reports

authors： Yeganeh Ghotbi M,Javanmard A,Soleimani H

更新日期：2018-02-21 00:00:00

abstract：:Naturally occurring metals and metalloids [metal(loid)s] are essential for the physiological functioning of wildlife; however, environmental contamination by metal(loid) and plastic pollutants is a health hazard. Metal(loid)s may interact with plastic in the environment and there is mixed evidence about whether plasti...

journal_title：Scientific reports

authors： Roman L,Kastury F,Petit S,Aleman R,Wilcox C,Hardesty BD,Hindell MA

更新日期：2020-10-22 00:00:00

abstract：:A fracture is the most dangerous complication of osteoporosis in patients because the associated disability and mortality rates are high. Osteoporosis impairs fracture healing and prognosis, but how intramembranous ossification (IO) or endochondral ossification (EO) during fracture healing are affected and whether the...

journal_title：Scientific reports

authors： Zhang H,Shi X,Wang L,Li X,Zheng C,Gao B,Xu X,Lin X,Wang J,Lin Y,Shi J,Huang Q,Luo Z,Yang L

更新日期：2018-03-01 00:00:00

abstract：:In the current study, the thermodynamics of the slag-metal equilibrium reaction between Inconel 718 Ni-based alloy and CaF2-CaO-Al2O3-MgO-TiO2 electroslag remelting (ESR)-type slags were systematically investigated in the temperature range from 1773 to 1973 K (1500 to 1700 °C). The equilibrium Al content increased wit...

journal_title：Scientific reports

authors： Duan S,Shi X,Mao M,Yang W,Han S,Guo H,Guo J

更新日期：2018-03-27 00:00:00

abstract：:The Asian citrus psyllid (ACP; Diaphorina citri) is the vector of Candidatus Liberibacter asiaticus (CLas) that is associated with the devastating Huanglongbing (HLB; citrus greening disease). This pest of Asian origin has spread into the Americas and more recently into a few countries in East Africa. During recent su...

journal_title：Scientific reports

authors： Oke AO,Oladigbolu AA,Kunta M,Alabi OJ,Sétamou M

更新日期：2020-06-10 00:00:00

abstract：:In the gastrointestinal (GI) epithelium, enterochromaffin (EC) cells are enteroendocrine cells responsible for producing >90% of the body's serotonin (5-hydroxytryptamine, 5-HT). However, the molecular mechanisms of EC cell function are poorly understood. Here, we found that EC cells in mouse primary cultures fired sp...

journal_title：Scientific reports

authors： Strege PR,Knutson K,Eggers SJ,Li JH,Wang F,Linden D,Szurszewski JH,Milescu L,Leiter AB,Farrugia G,Beyder A

更新日期：2017-11-15 00:00:00

abstract：:Barrett's esophagus (BE) is the only known precursor to esophageal adenocarcinoma (EAC). Methods of identifying BE patients at high risk for progression to high-grade dysplasia (HGD) or EAC are needed to improve outcomes and identify who will benefit most from intensive surveillance or ablative therapy. Clinical predi...

journal_title：Scientific reports

authors： Kambhampati S,Tieu AH,Luber B,Wang H,Meltzer SJ

更新日期：2020-03-17 00:00:00

abstract：:Mobile phone microscopes are a natural platform for point-of-care imaging, but current solutions require an externally powered illumination source, thereby adding bulk and cost. We present a mobile phone microscope that uses the internal flash or sunlight as the illumination source, thereby reducing complexity whilst ...

journal_title：Scientific reports

authors： Orth A,Wilson ER,Thompson JG,Gibson BC

更新日期：2018-02-19 00:00:00

abstract：:We report the high susceptibility of several clinical isolates of Propionibacterium acnes from different sources (skin, bone, wound exudates, abscess or blood contamination) to the head-to-tail cyclized bacteriocin AS-48. This peptide is a feasible candidate for further pharmacological development against this bacteri...

journal_title：Scientific reports

authors： Cebrián R,Arévalo S,Rubiño S,Arias-Santiago S,Rojo MD,Montalbán-López M,Martínez-Bueno M,Valdivia E,Maqueda M

更新日期：2018-08-06 00:00:00

abstract：:A theoretical investigation of the unique electronic transport properties of the junctions composed of boron nitride atomic chains bridging symmetric graphene electrodes with point-contacts is executed through non-equilibrium Green's function technique in combination with density functional theory. Compared with carbo...

journal_title：Scientific reports

authors： Xu X,Li W,Liu L,Feng J,Jiang Y,Tian WQ

更新日期：2016-05-23 00:00:00

abstract：:A delicate balance between proliferating and differentiating signals is necessary to ensure proper growth and neuronal specification. By studying the developing zebrafish brain, we observed a specific and dynamic expression of a microtubule destabilizer gene, stathmin-like 4 (stmn4), in the dorsal midbrain region. The...

journal_title：Scientific reports

authors： Lin MJ,Lee SJ

更新日期：2016-11-07 00:00:00

abstract：:Detecting and analysing motion is a key feature of Smart Homes and the connected sensor vision they embrace. At present, most motion sensors operate in line-of-sight Doppler shift schemes. Here, we propose an alternative approach suitable for indoor environments, which effectively constitute disordered cavities for ra...

journal_title：Scientific reports

authors： Del Hougne P,F Imani M,Sleasman T,Gollub JN,Fink M,Lerosey G,Smith DR

更新日期：2018-04-25 00:00:00

abstract：:RNA virus-based episomal vector (REVec) is an emerging viral vector system that mediates long-term stable gene expression in variety of cell types in vitro. However, little is known about its tissue tropism and persistence of gene expression in vivo. Here, to evaluate the feasibility of REVec for in vivo gene delivery...

journal_title：Scientific reports

authors： Komatsu Y,Tanaka C,Komorizono R,Tomonaga K

更新日期：2020-04-03 00:00:00

abstract：:A functional genetic switch from the lactococcal bacteriophage TP901-1, deciding which of two divergently transcribing promoters becomes most active and allows this bi-stable decision to be inherited in future generations requires a DNA region of less than 1 kb. The fragment encodes two repressors, CI and MOR, transcr...

journal_title：Scientific reports

authors： Pedersen M,Neergaard JT,Cassias J,Rasmussen KK,Lo Leggio L,Sneppen K,Hammer K,Kilstrup M

更新日期：2020-05-26 00:00:00

abstract：:Soil fauna are critical for ecosystem function and sensitive to the changes of soil fertility. The effects of fertilization on soil fauna communities, however, remain poorly understood. We examined the effects of fertilization form and quantity on the abundance, diversity and composition of soil fauna across an age-se...

journal_title：Scientific reports

authors： Wang S,Chen HY,Tan Y,Fan H,Ruan H

更新日期：2016-02-09 00:00:00

abstract：:Most bacterial cells are stressed, and as a result, some become tolerant to antibiotics by entering a dormant state known as persistence. The key intracellular metabolite that has been linked to this persister state is guanosine tetraphosphate (ppGpp), the alarmone that was first linked to nutrient stress. In Escheric...

journal_title：Scientific reports

authors： Chowdhury N,Kwan BW,Wood TK

更新日期：2016-02-03 00:00:00

abstract：:Transport of self-propelled particles in a two-dimensional (2D) separate channel is investigated in the presence of the combined forces. By applying an ac force, the particles will be trapped by the separate walls. A dc force produces the asymmetry of the system and induces the longitudinal directed transport. Due to ...

journal_title：Scientific reports

authors： Wu JC,Ai BQ

更新日期：2016-04-01 00:00:00

abstract：:With limited success achieved in bladder cancer patient management, novel agents are in urgent need for the purpose of therapy and prevention. As a sesquiterpenoid dimmer isolated from Gochnatia pomculat, (-)-gochnatiolide B has been bio-mimetically synthesized in multiple steps with a poor yield, which heavily limite...

journal_title：Scientific reports

authors： Chen Y,Li W,Zeng Z,Tang Y

更新日期：2018-06-11 00:00:00

abstract：:We examine the spin-dependent manipulating of vector beams by tailoring the inhomogeneous polarization. The spin-dependent manipulating is attributed to the spin-dependent phase gradient in vector beams, which can be regarded as the intrinsic feature of inhomogeneous polarization. The desired polarization can be obtai...

journal_title：Scientific reports

authors： Zhou J,Zhang W,Liu Y,Ke Y,Liu Y,Luo H,Wen S

更新日期：2016-09-28 00:00:00

abstract：:Bats of the Rhinolophidae and Hipposideridae families, and Pteronotus parnellii, compensate for Doppler shifts generated by their own flight movement. They adjust their call frequency such that the frequency of echoes coming from ahead fall in a specialized frequency range of the hearing system, the auditory fovea, to...

journal_title：Scientific reports

authors： Schoeppler D,Schnitzler HU,Denzinger A

更新日期：2018-03-15 00:00:00

abstract：:In many real-world networks, the ability to withstand targeted or global attacks; extinctions; or shocks is vital to the survival of the network itself, and of dependent structures such as economies (for financial networks) or even the planet (for ecosystems). Previous attempts to characterise robustness include neste...

journal_title：Scientific reports

authors： Burleson-Lesser K,Morone F,Tomassone MS,Makse HA

更新日期：2020-02-25 00:00:00

abstract：:Interferometry-based online partial discharge (PD) monitor presented in this paper can detect the occurrence of PD sensitively, evaluate the peak value of the discharge inception voltage with random waveform and the damage extent relatively cost effectively. The interferograms affected by the PD are collected online. ...

journal_title：Scientific reports

authors： Xue L,Zhu Y,Yang C,Kumarawadu S

更新日期：2020-11-04 00:00:00

abstract：:1,3,5-trinitroperhydro-1,3,5-triazine (RDX), octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine (HMX), and pentaerythritol tetranitrate (PETN), the major components in plastic explosives, pose a significant threat to public safety. A quick, sensitive, and low-cost detection method for these non-volatile explosives is ea...

journal_title：Scientific reports

authors： Wang C,Huang H,Bunes BR,Wu N,Xu M,Yang X,Yu L,Zang L

更新日期：2016-05-05 00:00:00

abstract：:The niacin receptor HCA2 is implicated in controlling inflammatory host responses with yet poorly understood mechanistic basis. We previously reported that HCA2 in A431 epithelial cells transduced Gβγ-protein kinase C- and Gβγ-metalloproteinase/EGFR-dependent MAPK/ERK signaling cascades. Here, we investigated the role...

journal_title：Scientific reports

authors： Shi Y,Lai X,Ye L,Chen K,Cao Z,Gong W,Jin L,Wang C,Liu M,Liao Y,Wang JM,Zhou N

更新日期：2017-02-10 00:00:00

abstract：:Teleportation plays an important role in the communication of quantum information between the nodes of a quantum network and is viewed as an essential ingredient for long-distance Quantum Cryptography. We describe a method to teleport the quantum information carried by a photon in a superposition of a number d of ligh...

journal_title：Scientific reports

authors： Goyal SK,Konrad T

更新日期：2013-12-19 00:00:00

abstract：:Knots are remarkable topological features in nature. The presence of knots in crystallographic structures of proteins have stimulated considerable research to determine the kinetic and thermodynamic consequences of threading a polypeptide chain. By mechanically manipulating MJ0366, a small single domain protein harbor...

journal_title：Scientific reports

authors： Rivera M,Hao Y,Maillard RA,Baez M

更新日期：2020-06-12 00:00:00