Stathmin-like 4 is critical for the maintenance of neural progenitor cells in dorsal midbrain of zebrafish larvae.

abstract：:Deformable elastomeric spheres are evaluated experimentally as they skip multiple times over a lake surface. Some spheres are embedded with small inertial measurement units to measure the acceleration experienced during water surface impact. A model for multiple impact events shows good agreement between measured acce...

journal_title：Scientific reports

authors： Hurd RC,Belden J,Bower AF,Holekamp S,Jandron MA,Truscott TT

更新日期：2019-04-15 00:00:00

abstract：:Large classes of electronic, photonic, and acoustic crystals and quasi-crystals have been predicted to support topological wave-modes. Some of these modes are stabilized by certain symmetries but others occur as pure wave phenomena, hence they can be observed in many other media that support wave propagation. Surface ...

journal_title：Scientific reports

authors： Apigo DJ,Kanwal A,Palmieri J,Dobiszewski KF,Farrow RC,Thomas GA,Prodan EV,Prodan C

更新日期：2018-02-20 00:00:00

abstract：:There is no preclinical mouse model to investigate pulmonary Mycobacteroides abscessus (formerly Mycobacterium abscessus) infection in an immunocompetent mouse strain, especially in the context of antibiotic testing and regimen development. We developed a mouse model of pulmonary M. abscessus infection using the aeros...

journal_title：Scientific reports

authors： Maggioncalda EC,Story-Roller E,Mylius J,Illei P,Basaraba RJ,Lamichhane G

更新日期：2020-02-28 00:00:00

abstract：:Membrane proteins are key elements in cell-mediated processes. In particular, G protein-coupled receptors (GPCRs) have attracted increasing interest since they affect cellular signaling. Furthermore, mutations in GPCRs can cause acquired and inheritable diseases. Up to date, there still exist a number of GPCRs that ha...

journal_title：Scientific reports

authors： Zemella A,Grossmann S,Sachse R,Sonnabend A,Schaefer M,Kubick S

更新日期：2017-06-16 00:00:00

abstract：:Magnetic carboxyl functional nanoporous polymer (MCFNP) was chemically fabricated by incorporation of magnetic Fe3O4 precursor into the carboxyl functional nanoporous polymer (CFNP). The as-synthesized MCFNP was characterized and used as an adsorbent for rapid adsorption removal of methylene blue (MB) from wastewater....

journal_title：Scientific reports

authors： Su H,Li W,Han Y,Liu N

更新日期：2018-04-25 00:00:00

abstract：:Abnormal expression of microRNAs (miRNAs) contributes to glioma initiation. However, the expression of miRNAs in tumour tissue or blood of spinal cord glioma (SCG) patients, particularly in high-grade spinal gliomas (Grade IV) known as glioblastoma (GBM), remains largely unknown. In this study we aimed to determine di...

journal_title：Scientific reports

authors： An T,Fan T,Zhang XQ,Liu YF,Huang J,Liang C,Lv BH,Wang YQ,Zhao XG,Liu JX,Fu YH,Jiang GJ

更新日期：2019-06-24 00:00:00

abstract：:RNA interference (RNAi) is being developed for the management of pests that destroy crops. The twospotted Spider Mite (TSSM), Tetranychus urticae is a worldwide pest due to its unique physiological and behavioral characteristics including extraordinary ability to detoxify a wide range of pesticides and feed on many ho...

journal_title：Scientific reports

authors： Yoon JS,Sahoo DK,Maiti IB,Palli SR

更新日期：2018-10-02 00:00:00

abstract：:Small-molecule inhibitors of non-canonical IκB kinases TANK-binding kinase 1 (TBK1) and IκB kinase ε (IKKε) have shown to stimulate β-cell regeneration in multiple species. Here we demonstrate that TBK1 is predominantly expressed in β-cells in mammalian islets. Proteomic and transcriptome analyses revealed that geneti...

journal_title：Scientific reports

authors： Jia YF,Jeeva S,Xu J,Heppelmann CJ,Jang JS,Slama MQ,Tapadar S,Oyelere AK,Kang SM,Matveyenko AV,Peterson QP,Shin CH

更新日期：2020-11-09 00:00:00

abstract：:Limited continuous replenishment of the mineralization medium is a restriction for in-situ solution-based remineralization of hypomineralized body tissues. Here, we report a process that generated amine-functionalized mesoporous silica nanoparticles for sustained release of biomimetic analog-stabilized amorphous calci...

journal_title：Scientific reports

authors： Zhang W,Luo XJ,Niu LN,Yang HY,Yiu CK,Wang TD,Zhou LQ,Mao J,Huang C,Pashley DH,Tay FR

更新日期：2015-06-08 00:00:00

abstract：:In southeastern China (SEC), the precipitation amount produced by the East Asian summer monsoon (EASM) is almost equivalent to that during the non-summer monsoon (NSM) period, both of them significantly affecting agriculture and socioeconomy. Here, we present a seasonally-resolved stalagmite δ18O record (δ18Os) for th...

journal_title：Scientific reports

authors： Zhang H,Cheng H,Spötl C,Cai Y,Sinha A,Tan L,Yi L,Yan H,Kathayat G,Ning Y,Li X,Zhang F,Zhao J,Edwards RL

更新日期：2018-08-17 00:00:00

abstract：:Caveolins are essential structural proteins driving the formation of caveolae, specialized invaginations of the plasma membrane. Loss of Caveolin-1 (Cav1) function in mice causes distinct neurological phenotypes leading to impaired motor control, however, the underlying developmental mechanisms are largely unknown. In...

journal_title：Scientific reports

authors： Breuer M,Berger H,Borchers A

更新日期：2020-10-05 00:00:00

abstract：:Vertical mixing modulates nutrient dynamics in lakes. However, surface warming reduces the range of vertical mixing and the probability of full circulation events. Important consequences of reduced vertical mixing include the sequestration of phosphorus (P) within a stagnant zone and the promotion of oligotrophication...

journal_title：Scientific reports

authors： Lau MP,Valerio G,Pilotti M,Hupfer M

更新日期：2020-07-31 00:00:00

abstract：:Lin28 is an evolutionary conserved RNA-binding protein that plays important roles during embryonic development and tumorigenesis. It regulates gene expression through two different post-transcriptional mechanisms. The first one is based on the regulation of miRNA biogenesis, in particular that of the let-7 family, who...

journal_title：Scientific reports

authors： Parisi S,Castaldo D,Piscitelli S,D'Ambrosio C,Divisato G,Passaro F,Avolio R,Castellucci A,Gianfico P,Masullo M,Scaloni A,Russo T

更新日期：2021-01-27 00:00:00

abstract：:Here we present an experimental as well as theoretical study of third-harmonic generation in tightly focused femtosecond filaments in air at the wavelength of [Formula: see text]. At low intensities, longitudinal phase matching is dominating in the formation of 3rd harmonics, whereas at higher intensities locked X-wav...

journal_title：Scientific reports

authors： Tamulienė V,Juškevičiūtė G,Buožius D,Vaičaitis V,Babushkin I,Morgner U

更新日期：2020-10-15 00:00:00

abstract：:Electron-hole exchange interaction in semiconductor quantum dots (QDs) splits the band-edge exciton manifold into optically active ("bright") and passive ("dark") states, leading to a complicated exciton fine structure. In the present work, we resolve by atomistic million-atom many-body pseudopotential calculations th...

journal_title：Scientific reports

authors： Baskoutas S,Zeng Z,Garoufalis CS,Bester G

更新日期：2017-08-24 00:00:00

abstract：:Microscopic swimming devices hold promise for radically new applications in lab-on-a-chip and microfluidic technology, diagnostics and drug delivery etc. In this paper, we demonstrate the experimental verification of a new class of autonomous ferromagnetic swimming devices, actuated and controlled solely by an oscilla...

journal_title：Scientific reports

authors： Hamilton JK,Petrov PG,Winlove CP,Gilbert AD,Bryan MT,Ogrin FY

更新日期：2017-03-09 00:00:00

abstract：:The East Asian Summer Monsoon driven by temperature and moisture gradients between the Asian continent and the Pacific Ocean, leads to approximately 50% of the annual rainfall in the region across 20-40°N. Due to its increasing scientific and social importance, there have been several previous studies on identificatio...

journal_title：Scientific reports

authors： Li S,Park S,Lee JY,Ha KJ,Park MK,Jo CO,Oh H,Mühle J,Kim KR,Montzka SA,O'Doherty S,Krummel PB,Atlas E,Miller BR,Moore F,Weiss RF,Wofsy SC

更新日期：2018-03-16 00:00:00

abstract：:The factors regulating phytoplankton community composition play a crucial role in structuring aquatic food webs. However, consensus is still lacking about the mechanisms underlying the observed biogeographical differences in cell size composition of phytoplankton communities. Here we use a trait-based model to disenta...

journal_title：Scientific reports

authors： Acevedo-Trejos E,Brandt G,Bruggeman J,Merico A

更新日期：2015-03-09 00:00:00

abstract：:The plasmonic waveguide made of uniform corrugated metallic strip can support and guide spoof surface plasmon polaritons (SSPPs) with high confinements. Here, we propose periodically-modulated plasmonic waveguide composed of non-uniform corrugated metallic strip to convert SSPPs to radiating waves, in which the main b...

journal_title：Scientific reports

authors： Kong GS,Ma HF,Cai BG,Cui TJ

更新日期：2016-07-12 00:00:00

abstract：:Neutron energy is directly correlated with the energy of the incident ions in experiments involving laser-driven nuclear reactions. Using high-energy incident ions reduces the energy concentration of the generated neutrons. A novel "laser-collider" method was used at the Shenguang II laser facility to produce monoener...

journal_title：Scientific reports

authors： Zhao JR,Zhang XP,Yuan DW,Li YT,Li DZ,Rhee YJ,Zhang Z,Li F,Zhu BJ,Li YF,Han B,Liu C,Ma Y,Li YF,Tao MZ,Li MH,Guo X,Huang XG,Fu SZ,Zhu JQ,Zhao G,Chen LM,Fu CB,Zhang J

更新日期：2016-06-02 00:00:00

abstract：:Human papillomavirus (HPV) infection, a primary cause of genital cancer, is also related to the increasing incidence of oropharyngeal cancer among young men. Relatively little is known about the concurrence of oral and genital infection among healthy individuals. Oral and genital swab exfoliated cells were collected s...

journal_title：Scientific reports

authors： Liu F,Hang D,Deng Q,Liu M,Xi L,He Z,Zhang C,Sun M,Liu Y,Li J,Pan Y,Ning T,Guo C,Liang Y,Xu R,Zhang L,Cai H,Ke Y

更新日期：2015-10-27 00:00:00

abstract：:The maternal environment can influence the intensity of seed dormancy and thus seasonal germination timing and post-germination life history traits. We tested the hypotheses that germination season influences phenotypic expression of post-germination life history traits in the cold desert annual Isatis violascens and ...

journal_title：Scientific reports

authors： Lu JJ,Tan DY,Baskin CC,Baskin JM

更新日期：2016-04-27 00:00:00

abstract：:Pediatric obstructive sleep-disordered breathing is associated with growth retardation, but also with obesity that has a tendency to persist following treatment. We investigated the effect of upper airways obstruction (AO) and of obstruction removal (OR) in juvenile rats on gut-derived ghrelin and related hypothalamic...

journal_title：Scientific reports

authors： Assadi MH,Shknevsky E,Segev Y,Tarasiuk A

更新日期：2017-06-02 00:00:00

abstract：:Malignant transformation results in increased levels of reactive oxygen species (ROS). Adaption to this toxic stress allows cancer cells to proliferate. Recently, piperlongumine (PL), a natural alkaloid, was identified to exhibit novel anticancer effects by targeting ROS signaling. PL induces apoptosis specifically in...

journal_title：Scientific reports

authors： Li J,Sharkey CC,King MR

更新日期：2015-05-18 00:00:00

abstract：:There is widespread transcriptional dysregulation in Huntington's disease (HD) brain, but analysis is inevitably limited by advanced disease and postmortem changes. However, mutant HTT is ubiquitously expressed and acts systemically, meaning blood, which is readily available and contains cells that are dysfunctional i...

journal_title：Scientific reports

authors： Hensman Moss DJ,Flower MD,Lo KK,Miller JR,van Ommen GB,'t Hoen PA,Stone TC,Guinee A,Langbehn DR,Jones L,Plagnol V,van Roon-Mom WM,Holmans P,Tabrizi SJ

更新日期：2017-03-21 00:00:00

abstract：:Glaulactams A-C (1-3), which possess a novel skeleton, as well as the known compound daphmanidin B (4), were isolated from the leaves of Daphniphyllum glaucescens and separated using ion-exchange chromatography aided by NMR fingerprinting. Their structures, including their absolute configurations, were elucidated by s...

journal_title：Scientific reports

authors： Chao CH,Cheng JC,Gonçalves TP,Huang KW,Lin CC,Huang HC,Hwang SY,Wu YC

更新日期：2018-10-18 00:00:00

abstract：:Targeting cancer-associated fibroblasts (CAFs), as well as the crosstalk between stroma and cancer cells, could be of value in managing cancers. Pirfenidone (PFD) is an anti-fibrotic agent for idiopathic pulmonary fibrosis. This study aimed to investigate the possibility that PFD might exert an anti-tumor effect throu...

journal_title：Scientific reports

authors： Fujiwara A,Funaki S,Fukui E,Kimura K,Kanou T,Ose N,Minami M,Shintani Y

更新日期：2020-07-02 00:00:00

abstract：:The production of tuberous roots is usually reduced by vigorous vegetative growth because of the competition for resource between the vegetative parts and reproductive organs. In this study, we conducted root pruning to examine the vigorous vegetative growth by regulating root growth, subsequently limiting vegetative ...

journal_title：Scientific reports

authors： Gao K,Zhu T,Wang L,Gao Y

更新日期：2018-03-13 00:00:00

abstract：:The Late Pleistocene Campanian Ignimbrite (CI) super-eruption (Southern Italy) is the largest known volcanic event in the Mediterranean area. The CI tephra is widely dispersed through western Eurasia and occurs in close stratigraphic association with significant palaeoclimatic and Palaeolithic cultural events. Here we...

journal_title：Scientific reports

authors： Giaccio B,Hajdas I,Isaia R,Deino A,Nomade S

更新日期：2017-04-06 00:00:00

abstract：:The aims of this study were as follows: to estimate the mortality and years of life lost, assessed by disability-adjusted life years (DALYs), due to breast cancer attributable to physical inactivity in Brazilian women; to compare the estimates attributable to physical inactivity and to other modifiable risk factors; a...

journal_title：Scientific reports

authors： Silva DAS,Tremblay MS,Souza MFM,Guerra MR,Mooney M,Naghavi M,Malta DC

更新日期：2018-07-24 00:00:00