Identification of target genes for RNAi-mediated control of the Twospotted Spider Mite.

abstract：:We assessed 1-year outcomes in patients with atrial fibrillation enrolled in the EurObservational Research Programme AF General Pilot Registry (EORP-AF), in relation to kidney function, as assessed by glomerular filtration rate (eGFR). In a cohort of 2398 patients (median age 69 years; 61% male), eGFR (ml/min/1.73 m(2...

journal_title：Scientific reports

authors： Boriani G,Laroche C,Diemberger I,Popescu MI,Rasmussen LH,Petrescu L,Crijns HJGM,Tavazzi L,Maggioni AP,Lip GYH

更新日期：2016-07-28 00:00:00

abstract：:The analysis of structural and functional neuroimaging data using graph theory has increasingly become a popular approach for visualising and understanding anatomical and functional relationships between different cerebral areas. In this work we applied a network-based approach for brain PET studies using population-b...

journal_title：Scientific reports

authors： Veronese M,Moro L,Arcolin M,Dipasquale O,Rizzo G,Expert P,Khan W,Fisher PM,Svarer C,Bertoldo A,Howes O,Turkheimer FE

更新日期：2019-02-21 00:00:00

abstract：:Anti-PD-1 antibodies revolutionized the treatment of advanced melanoma patients. However, one out of three do not respond to this therapy, with an overall poor prognosis. Identification of predictive biomarkers in patients receiving immune-based therapies is necessary for minimizing risk of toxicity and optimizing pat...

journal_title：Scientific reports

authors： Giunta EF,Barra G,De Falco V,Argenziano G,Napolitano S,Vitale P,Zanaletti N,Terminiello M,Martinelli E,Morgillo F,Ciardiello D,De Palma R,Ciardiello F,Troiani T

更新日期：2020-10-19 00:00:00

abstract：:We performed continuous recordings (May 2015 - January 2017) of hydraulic pressure and electrical conductivity of groundwater in the 190 m-long horizontal S13 borehole drilled next to the deep underground laboratories of Gran Sasso (LNGS-INFN), located in the core of the Gran Sasso carbonate aquifer (central Italy) at...

journal_title：Scientific reports

authors： De Luca G,Di Carlo G,Tallini M

更新日期：2018-10-29 00:00:00

abstract：:Rs1042522 (Arg72Pro) is a functional polymorphism of TP53. Pro72 has been associated with lower all-cause mortality and lower mortality after cancer. We hypothesized that TP53 Pro72 is associated with lower mortality after cancer, lower all-cause mortality, and with increased cancer incidence in the general population...

journal_title：Scientific reports

authors： Kodal JB,Vedel-Krogh S,Kobylecki CJ,Nordestgaard BG,Bojesen SE

更新日期：2017-03-23 00:00:00

abstract：:Lipomas are benign fatty tumors with a high prevalence rate, mostly found in adults but have a good prognosis. Until now, reason for lipoma occurrence not been identified. We performed whole exome sequencing to define the mutational spectrum in ten lipoma patients along with their matching control samples. We presente...

journal_title：Scientific reports

authors： Kanojia D,Dakle P,Mayakonda A,Parameswaran R,Puhaindran ME,Min VLK,Madan V,Koeffler P

更新日期：2019-10-07 00:00:00

abstract：:The prognostic value of current multigene assays for breast cancer is limited to hormone receptor-positive, human epidermal growth factor receptor 2-negative early breast cancer. Despite the prognostic significance of immune response-related genes in breast cancer, immune gene signatures have not been incorporated int...

journal_title：Scientific reports

authors： Lee H,Kwon MJ,Koo BM,Park HG,Han J,Shin YK

更新日期：2021-01-08 00:00:00

abstract：:The Edinburgh Postnatal Depression Scale (EPDS) is frequently used to screen for postpartum depression. However, its factor structure exhibits noticeable inconsistencies between studies. We examined the EPDS at two postpartum time points using a large dataset from outside Western countries. Participants were 91,063 mo...

journal_title：Scientific reports

authors： Matsumura K,Hamazaki K,Tsuchida A,Kasamatsu H,Inadera H,Japan Environment and Children’s Study (JECS) Group.

更新日期：2020-07-15 00:00:00

abstract：:Plant species of the genus Cecropia (Urticaceae) are used as traditional medicine in Latin-America, and are commercially available as food supplements. The aim of this study was to characterize and compare the phytochemical constituents of four Cecropia species collected in Panama. The structures of 11 compounds isola...

journal_title：Scientific reports

authors： Rivera-Mondragón A,Bijttebier S,Tuenter E,Custers D,Ortíz OO,Pieters L,Caballero-George C,Apers S,Foubert K

更新日期：2019-02-11 00:00:00

abstract：:This study shows that DKK-1, a member of the Dickkopf family and a regulator of the Wnt pathways, represents a novel target of statins which, through the inhibition of HMG-CoA reductase and of non-steroidal isoprenoid intermediates, exert extra-beneficial effect in preventing atherosclerosis beyond their effect on the...

journal_title：Scientific reports

authors： Pontremoli M,Brioschi M,Baetta R,Ghilardi S,Banfi C

更新日期：2018-11-12 00:00:00

abstract：:Huntington's disease (HD) is a monogenetic neurodegenerative disorder that is caused by the expansion of a polyglutamine region within the huntingtin (HTT) protein, but there is still an incomplete understanding of the molecular mechanisms that drive pathology. Expression of the mutant form of HTT is a key aspect of d...

journal_title：Scientific reports

authors： Fodale V,Pintauro R,Daldin M,Altobelli R,Spiezia MC,Bisbocci M,Macdonald D,Bresciani A

更新日期：2020-12-17 00:00:00

abstract：:Rare individuals remain cognitively intact despite the presence of neuropathology usually associated with fully symptomatic Alzheimer's disease (AD), which we refer to as Non-Demented with Alzheimer's disease Neuropathology (NDAN). Understanding the involved mechanism(s) of their cognitive resistance may reveal novel ...

journal_title：Scientific reports

authors： Briley D,Ghirardi V,Woltjer R,Renck A,Zolochevska O,Taglialatela G,Micci MA

更新日期：2016-06-14 00:00:00

abstract：:Myostatin (Mstn) is a conserved negative regulator of skeletal muscle mass in mammals. However, whether precise disruption of Mstn in livestock can be achieved and safely used to improve meat productivity has not been proven. We applied CRISPR/Cas9 system to generate Mstn knock-out (KO) rabbits and goats and then anal...

journal_title：Scientific reports

authors： Guo R,Wan Y,Xu D,Cui L,Deng M,Zhang G,Jia R,Zhou W,Wang Z,Deng K,Huang M,Wang F,Zhang Y

更新日期：2016-07-15 00:00:00

abstract：:We study the dynamical Casimir-Polder force on a two-level atom with different initial states in the one-dimensional dielectric cavity with output coupling, and obtain the analytical expression of the expectation value of dynamical Casimir-Polder force. Results show that the expectation values of dynamical Casimir-Pol...

journal_title：Scientific reports

authors： Long Y,Wang W,Zhang X,Yang H,Zheng T

更新日期：2020-07-20 00:00:00

abstract：:How chromosomes fold into 3D structures and how genome functions are affected or even controlled by their spatial organization remain challenging questions. Hi-C experiment has provided important structural insights for chromosome, and Hi-C data are used here to construct the 3D chromatin structure which are character...

journal_title：Scientific reports

authors： Xie WJ,Meng L,Liu S,Zhang L,Cai X,Gao YQ

更新日期：2017-06-06 00:00:00

abstract：:Despite a long history, the clinical efficacy of cupping therapy is still under debate. This is likely due to the lack of direct evidence for the biological actions of cupping, since the short exposure of cells to vacuum condition rarely has affects cellular activity. In this study, the medicinal properties of a recen...

journal_title：Scientific reports

authors： Lee HY,Lee HJ,Kim GC,Choi JH,Hong JW

更新日期：2019-03-07 00:00:00

abstract：:Ribosome biogenesis and turnover are processes necessary for cell viability and proliferation, and many kinds of proteins are known to regulate these processes. However, many questions still remain, especially in the Archaea. Generally, several ribonucleases are required to process precursor rRNAs to their mature form...

journal_title：Scientific reports

authors： Ikeda Y,Okada Y,Sato A,Kanai T,Tomita M,Atomi H,Kanai A

更新日期：2017-10-04 00:00:00

abstract：:The distinguishing of the multiphoton quantum interference effect from the classical one forms one of the most important issues in modern quantum mechanics and experimental quantum optics. For a long time, the two-photon interference (TPI) of correlated photons has been recognized as a pure quantum effect that cannot ...

journal_title：Scientific reports

authors： Kim H,Kwon O,Moon HS

更新日期：2019-12-05 00:00:00

abstract：:Marine biofouling remains an unsolved problem with a serious economic impact on several marine associated industries and constitutes a major vector for the spread of non-indigenous species (NIS). The implementation of biofouling monitoring programs allows for better fouling management and also for the early identifica...

journal_title：Scientific reports

authors： Azevedo J,Antunes JT,Machado AM,Vasconcelos V,Leão PN,Froufe E

更新日期：2020-08-10 00:00:00

abstract：:Drought stress and pathogen infection simultaneously occur in the field. In this study, the interaction of these two stresses with chickpea, their individual and combined effect and the net impact on plant growth and yield traits were systematically assessed under field and confined pot experiments. The field experime...

journal_title：Scientific reports

authors： Sinha R,Irulappan V,Mohan-Raju B,Suganthi A,Senthil-Kumar M

更新日期：2019-04-03 00:00:00

abstract：:Drug delivery by topical application has higher patient acceptance and lower morbidity than intraocular injection, but many ophthalmic treatments are unable to enter the eye or reach the posterior segment after topical application. The first stage towards posterior segment delivery after topical application is ocular ...

journal_title：Scientific reports

authors： Begum G,Leigh T,Courtie E,Moakes R,Butt G,Ahmed Z,Rauz S,Logan A,Blanch RJ

更新日期：2020-07-16 00:00:00

abstract：:Inhibition of return (IOR), typically explored in cueing paradigms, is a performance cost associated with previously attended locations and has been suggested as a crucial attentional mechanism that biases orientation towards novelty. In their seminal IOR paper, Posner and Cohen (1984) showed that IOR is coded in spat...

journal_title：Scientific reports

authors： He T,Ding Y,Wang Z

更新日期：2015-11-13 00:00:00

abstract：:East Asian summer monsoon (EASM)-driven rapid hydroclimatic variation is a crucial factor with major socioeconomic impacts. Nevertheless, decadal- to centennial-scale EASM variability over the last two millennia is still poorly understood. Pollen-based quantitative annual precipitation (PqPann) and annual precipitatio...

journal_title：Scientific reports

authors： Yi S,Jun CP,Jo KN,Lee H,Kim MS,Lee SD,Cao X,Lim J

更新日期：2020-10-20 00:00:00

abstract：:We report a novel and facile method to synthesize sulfur-doped titanium oxide sheets and realize TiS2-TiO2 heterostructures by means of a sequential sulfurization and oxidation step in a dual-zone chemical vapor deposition furnace. The inclusion of chlorine and argon gases during the growth of such titanium-based comp...

journal_title：Scientific reports

authors： Etghani SA,Ansari E,Mohajerzadeh S

更新日期：2019-11-29 00:00:00

abstract：:A light reflection device combined with visible light spectrophotometer was used to measure the reflectance-wavelength curves of colored stainless steel after coloring, hardening and sealing. After these processes, the coordinate in CIE 1931 color coordinate system and brightness of samples were confirmed by chromatom...

journal_title：Scientific reports

authors： Ji K,Ju H,Xun J,Su Y,Zhang K,Liu P,Xue Y

更新日期：2020-08-11 00:00:00

abstract：:Pannexin 1 (Panx1) forms ATP-permeable membrane channels that play roles in the nervous system. The analysis of roles in both standard and pathological conditions benefits from a model organism with rapid development and early onset of behaviors. Such a model was developed by ablating the zebrafish panx1a gene using T...

journal_title：Scientific reports

authors： Safarian N,Whyte-Fagundes P,Zoidl C,Grigull J,Zoidl G

更新日期：2020-06-12 00:00:00

abstract：:Interleukin-6 (IL-6) overproduction has been involved in the pathogenesis of several chronic inflammatory diseases and the administration of an anti-IL-6 receptor monoclonal antibody has been proven clinically efficient to treat them. However, the drawbacks of monoclonal antibodies have led our group to develop an inn...

journal_title：Scientific reports

authors： Desallais L,Bouchez C,Mouhsine H,Moreau G,Ratsimandresy R,Montes M,Do H,Quintin-Colonna F,Zagury JF

更新日期：2016-01-19 00:00:00

abstract：:The removal of macroalgal biomass is critical to the health of coral reef ecosystems. Previous studies on relatively intact reefs with diverse and abundant fish communities have quantified rapid removal of macroalgae by herbivorous fishes, yet how these findings relate to degraded reef systems where fish diversity and...

journal_title：Scientific reports

authors： Bauman AG,Hoey AS,Dunshea G,Feary DA,Low J,Todd PA

更新日期：2017-08-21 00:00:00

abstract：:Electroencephalographic hyperscanning was used to investigate interbrain synchronization patterns in dyads of participants interacting through speech. Results show that brain oscillations are synchronized between listener and speaker during oral narratives. This interpersonal synchronization is mediated in part by a l...

journal_title：Scientific reports

authors： Pérez A,Carreiras M,Duñabeitia JA

更新日期：2017-06-23 00:00:00

abstract：:Light regulates cGMP concentration in the photoreceptor cytoplasm by activating phosphodiesterase (PDE) molecules through a G-protein signalling cascade. Spontaneous PDE activity is present in rod outer segments even in darkness. This basal PDE activity (βdark) has not been determined in wild type mammalian photorecep...

journal_title：Scientific reports

authors： Turunen TT,Koskelainen A

更新日期：2019-02-04 00:00:00