Abstract：
:Limited continuous replenishment of the mineralization medium is a restriction for in-situ solution-based remineralization of hypomineralized body tissues. Here, we report a process that generated amine-functionalized mesoporous silica nanoparticles for sustained release of biomimetic analog-stabilized amorphous calcium phosphate precursors. Both two-dimensional and three-dimensional collagen models can be intrafibrillarly mineralized with these released fluidic intermediate precursors. This represents an important advance in the translation of biomineralization concepts into regimes for in-situ remineralization of bone and teeth.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Zhang W,Luo XJ,Niu LN,Yang HY,Yiu CK,Wang TD,Zhou LQ,Mao J,Huang C,Pashley DH,Tay FRdoi
10.1038/srep11199subject
Has Abstractpub_date
2015-06-08 00:00:00pages
11199issn
2045-2322pii
srep11199journal_volume
5pub_type
杂志文章abstract：:We study the effects of electrical and chemical autapse on the temporal coherence or firing regularity of single stochastic Hodgkin-Huxley neurons and scale-free neuronal networks. Also, we study the effects of chemical autapse on the occurrence of spatial synchronization in scale-free neuronal networks. Irrespective ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep30914
更新日期：2016-08-02 00:00:00
abstract：:Phase estimation represents a crucial challenge in many fields of Physics, ranging from Quantum Metrology to Quantum Information Processing. This task is usually pursued by means of interferometric schemes, in which the choice of the input states and of the detection apparatus is aimed at minimizing the uncertainty in...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep26025
更新日期：2016-05-18 00:00:00
abstract：:The MEN1 gene, which encodes the protein Menin, was investigated for its regulatory role in milk protein synthesis in mammary glands. Menin responds to nutrient and hormone levels via the PI3K/Akt/mTOR pathway. Bovine mammary epithelial cells and tissues were used as experimental models in this study. The results reve...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-06054-w
更新日期：2017-07-14 00:00:00
abstract：:The stria vascularis (SV) in the cochlea generates and maintains the endocochlear potential, thereby playing a pivotal role in normal hearing. Knowing transcriptional profiles and gene regulatory networks of SV cell types establishes a basis for studying the mechanism underlying SV-related hearing loss. While we have ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-75238-8
更新日期：2020-10-22 00:00:00
abstract：:We present herein the use of nanoporous anodic alumina (NAA) as a suitable support to implement "molecular gates" for sensing applications. In our design, a NAA support is loaded with a fluorescent reporter (rhodamine B) and functionalized with a short single-stranded DNA. Then pores are blocked by the subsequent hybr...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep38649
更新日期：2016-12-07 00:00:00
abstract：:The aquatic and semiaquatic invertebrates in fossiliferous amber have been reported, including taxa in a wide range of the subphylum Crustacea of Arthropoda. However, no caridean shrimp has been discovered so far in the world. The shrimp Palaemon aestuarius sp. nov. (Palaemonidae) preserved in amber from Chiapas, Mexi...
journal_title：Scientific reports
pub_type： 历史文章,杂志文章
doi：10.1038/s41598-019-51218-5
更新日期：2019-10-29 00:00:00
abstract：:Clinical practice guides recommend delayed clamping of the umbilical cord. If this is not possible, some authors suggest milking as an alternative. The objective of this study was to determine the variability in professional practice in the management of umbilical cord clamping and milking and to identify factors or c...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-58641-z
更新日期：2020-02-03 00:00:00
abstract：:Hydrogen is known to be present as an impurity in amorphous oxide semiconductors at the 0.1% level. Using amorphous ZnO as a simplified model system, we show that the hydrogens pair up at oxygen vacancies in the amorphous network, where they form metal-H-metal bridge bonds. These bonds are shown to create filled defec...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-17290-5
更新日期：2017-12-04 00:00:00
abstract：:Treatment of decompensated heart failure often includes administration of levosimendan. Myeloperoxidase (MPO) is released during polymorphonuclear neutrophil (PMN) degranulation, and mediates dysregulation of vascular tone in heart failure. We evaluated the effects of levosimendan-treatment on MPO in patients with acu...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep09704
更新日期：2015-04-13 00:00:00
abstract：:This study aimed to investigate the basilar artery (BA) geometric changes in a longitudinal study. 154 subjects with normal vertebrobasilar arterial systems on magnetic resonance angiography were assigned into two groups: 1) non-dominant vertebral artery (VA) and 2) VA dominance. We defined the dominant VA as either t...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-65682-x
更新日期：2020-06-01 00:00:00
abstract：:Within the framework of precision agriculture, the determination of various soil properties is moving into focus, especially the demand for sensors suitable for in-situ measurements. Energy-dispersive X-ray fluorescence (EDXRF) can be a powerful tool for this purpose. In this study a huge diverse soil set (n = 598) fr...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-53426-5
更新日期：2019-11-26 00:00:00
abstract：:An accurate method to predict the mortality in the intensive care unit (ICU) patients has been required, especially in children. The aim of this study is to evaluate the value of serum anion gap (AG) for predicting mortality in pediatric ICU (PICU). We reviewed a data of 461 pediatric patients were collected on PICU a...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-01681-9
更新日期：2017-05-03 00:00:00
abstract：:Caspase-1, also known as interleukin-1β (IL-1β)-converting enzyme (ICE), regulates antimicrobial host defense, tissue repair, tumorigenesis, metabolism and membrane biogenesis. On activation within an inflammasome complex, caspase-1 induces pyroptosis and converts pro-IL-1β and pro-IL-18 into their biologically active...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep45126
更新日期：2017-03-27 00:00:00
abstract：:Bacterial biofilms are particularly problematic since they become resistant to most available antibiotics. Hence, novel potential antagonists to inhibit biofilm formation are urgent. Here the influences of two natural products, ursolic acid and resveratrol, on biofilm of the clinical methicillin-resistant Staphylococc...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep05467
更新日期：2014-06-27 00:00:00
abstract：:Herein, we have fabricated rutile TiO2 nanorod-coupled α-Fe2O3 by a wet-chemical process. It is demonstrated that the visible activities for photoelectrochemical water oxidation and for degrading pollutant of α-Fe2O3 are greatly enhanced after coupling a proper amount of rutile nanorods. The enhanced activity is attri...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep06180
更新日期：2014-08-26 00:00:00
abstract：:Fluorescence is widespread in marine organisms but uncommon in terrestrial tetrapods. We here show that many chameleon species have bony tubercles protruding from the skull that are visible through their scales, and fluoresce under UV light. Tubercles arising from bones of the skull displace all dermal layers other th...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-19070-7
更新日期：2018-01-15 00:00:00
abstract：:We previously identified novel bioactive polysaccharides from Bactrocera cucurbitae and Antheraea yamamai that activate innate immunity in RAW264 murine macrophages. However, in terms of potential applications in the cultivation of prawns, there were problems with the availability of these insects. However, we have no...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-27241-3
更新日期：2018-06-11 00:00:00
abstract：:Breast cancer is a heterogeneous disease with differences in its clinical, molecular and biological features. Traditionally, immunohistochemical markers together with clinicopathologic parameters are used to classify breast cancer and to predict disease outcome. Triple-negative breast cancer (TNBC) is a particular typ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep44414
更新日期：2017-03-15 00:00:00
abstract：:Improving the affinity of protein-protein interactions is a challenging problem that is particularly important in the development of antibodies for diagnostic and clinical use. Here, we used structure-based computational methods to optimize the binding affinity of VHNAC1, a single-domain intracellular antibody (intrab...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-35464-7
更新日期：2018-12-04 00:00:00
abstract：:microRNAs regulate the expression of over 60% of protein coding genes by targeting their mRNAs to AGO2-containing complexes in the cytoplasm and promoting their translational inhibition and/or degradation. There is little evidence so far for microRNA-mediated regulation of other classes of non-coding RNAs. Here we rep...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep02535
更新日期：2013-01-01 00:00:00
abstract：:The health risks associated with spaceflight-induced ocular structural and functional damage has become a recent concern for NASA. The goal of the present study was to characterize the effects of spaceflight and reentry to 1 g on the structure and integrity of the retina and blood-retinal barrier (BRB) in the eye. To ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-44696-0
更新日期：2019-06-03 00:00:00
abstract：:Magnetic materials have found wide application ranging from electronics and memories to medicine. Essential to these advances is the control of the magnetic order. To date, most room-temperature applications have a fixed magnetic moment whose orientation is manipulated for functionality. Here we demonstrate an iron-ox...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep11430
更新日期：2015-06-23 00:00:00
abstract：:We demonstrate theoretically that photon-photon attraction can be engineered in the continuum of scattering states for pairs of photons propagating in a hollow-core photonic crystal fiber filled with cold atoms. The atoms are regularly spaced in an optical lattice configuration and the photons are resonantly tuned to ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep25630
更新日期：2016-05-12 00:00:00
abstract：:An appropriate tillage method must be implemented by maize growers to improve phosphorus dynamics in the soil in order to increase phosphorus uptake by plant. The objective of this study was to investigate the effects of tillage systems on phosphorus and its fractions in rhizosphere and non-rhizosphere soils under mai...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-63567-7
更新日期：2020-04-20 00:00:00
abstract：:Soil pH is commonly considered a dominant factor affecting the function of microbiota. Few studies, however, have focused on communities of bacteria able to solubilize inorganic phosphate (iPSB), which are important for the mobilization of soil phosphorus (P), because finding an effective method to assess the abundanc...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-37003-w
更新日期：2019-01-10 00:00:00
abstract：:The self-organisation of void and gas bubbles in solids into superlattices is an intriguing nanoscale phenomenon. Despite the discovery of these lattices 45 years ago, the atomistics behind the ordering mechanisms responsible for the formation of these nanostructures are yet to be fully elucidated. Here we report on t...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-07711-w
更新日期：2017-08-10 00:00:00
abstract：:The capacity of graphene oxide nanoparticles (nGOx) to reduce or increase As and metals availability in polluted soils was compared with that of zero valent iron nanoparticles (nZVI). The nanomaterials used in this study were characterized by X-ray techniques, CHNS-O analysis, dynamic light scattering, and microscopy ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-58852-4
更新日期：2020-02-05 00:00:00
abstract：:Atherosclerosis is a progressive disease leading to loss of vascular homeostasis and entails fibrosis, macrophage foam cell formation, and smooth muscle cell proliferation. Recent studies have reported that epidermal growth factor receptor (EGFR) is involved vascular pathophysiology and in the regulation of oxidative ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep45917
更新日期：2017-04-04 00:00:00
abstract：:Site-specific genome modification (SSM) is an important tool for mosquito functional genomics and comparative gene expression studies, which contribute to a better understanding of mosquito biology and are thus a key to finding new strategies to eliminate vector-borne diseases. Moreover, it allows for the creation of ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep43883
更新日期：2017-03-07 00:00:00
abstract：:Cell counts decrease with sediment depth. Typical explanations consider limiting factors such as water availability and chemistry, carbon source, nutrients, energy and temperature, and overlook the role of pore size. Our analyses consider sediment self-compaction, the evolution of pore size with depth, and the probabi...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-78714-3
更新日期：2020-12-10 00:00:00
