Abstract:
:Vertical mixing modulates nutrient dynamics in lakes. However, surface warming reduces the range of vertical mixing and the probability of full circulation events. Important consequences of reduced vertical mixing include the sequestration of phosphorus (P) within a stagnant zone and the promotion of oligotrophication. Nevertheless, warming-induced shifts from full to partial mixing (meromixis) are not permanent and are partially reversible during exceptionally cold or windy winters. In this study, we investigated how intermittent meromixis affects lake P budgets. We examined the P cycle of a perialpine lake with variable mixing depths by pairing sedimentation and release flux measurements with sedimentary archives. We found that the amount of dissolved P surpassed that of the potentially mobile P in the sediments by a 13:1 ratio. At least 55% of the settled P was rapidly released to bottom waters isolated from flushing, illustrating the general biogeochemical mechanism that promotes deep-water P storage when lakes undergo warming. This storage process is abruptly inverted when meromixis suddenly retreats, deeper mixing introduces P pulses to the surface waters, thereby promoting phytoplankton proliferation. Our estimates showed that lakes containing up to 40% of the global freshwater volume could shift towards intermittent meromixis if the atmospheric warming trend continues. Thus, these lakes might accumulate 0-83% of their P load in irregularly circulating waters and are prone to large P pulses.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Lau MP,Valerio G,Pilotti M,Hupfer Mdoi
10.1038/s41598-020-69721-5subject
Has Abstractpub_date
2020-07-31 00:00:00pages
12928issue
1issn
2045-2322pii
10.1038/s41598-020-69721-5journal_volume
10pub_type
杂志文章abstract::Although large populations feel fatigue, the standardized medicinal therapy is currently absent. In this study, we determined whether 5-aminolevulinic acid (5-ALA) supplementation alleviates the feeling of fatigue in healthy subjects who feel chronic physical tiredness. Males and females between ages of 20 and 64 who ...
journal_title:Scientific reports
pub_type: 杂志文章,随机对照试验
doi:10.1038/s41598-020-72763-4
更新日期:2020-09-29 00:00:00
abstract::Multilevel severe compressive myelopathy is a challenging disorder for the surgeons, the aim of this study is to assess the efficacy and safety of a newly designed ultrasonic burr as an assistant tool to the ultrasonic scalpel in laminectomy for this disease. This is a retrospective comparative study, the included sub...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-22454-y
更新日期:2018-03-05 00:00:00
abstract::Emerging infectious diseases such as chytridiomycosis and ranavirus infections are important contributors to the worldwide decline of amphibian populations. We reviewed data on 247 anuran mortality events in 43 States of the United States from 1999-2015. Our findings suggest that a severe infectious disease of tadpole...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-10456-1
更新日期:2017-08-31 00:00:00
abstract::Most published sleep studies use three species: human, house mouse, or Norway rat. The degree to which data from these species captures variability in mammalian sleep remains unclear. To gain insight into mammalian sleep diversity, we examined sleep architecture in the spiny basal murid rodent Acomys cahirinus. First,...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-67859-w
更新日期:2020-07-02 00:00:00
abstract::This work aimed to use artificial intelligence to predict subjective refraction from wavefront aberrometry data processed with a novel polynomial decomposition basis. Subjective refraction was converted to power vectors (M, J0, J45). Three gradient boosted trees (XGBoost) algorithms were trained to predict each power ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-65417-y
更新日期:2020-05-22 00:00:00
abstract::Synthetic analogues of mycobacterial trehalose-dimycolate such as trehalose acyl esters have been proposed as novel adjuvants for vaccination. They induce an immune response by binding to the macrophage C-type lectin receptor Mincle. The binding site of trehalose is known, but there is yet only very limited structural...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-23624-8
更新日期:2018-03-29 00:00:00
abstract::Jute fibre is the second most important fibre next to cotton. It is obtained from the bark of plant through microbial retting process. Here we report optimized microbial retting protocol that can lower retting period and produce high fibre quality. A total of 451 bacterial colonies have been isolated from five jute re...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-61898-z
更新日期:2020-03-20 00:00:00
abstract::Elucidating arbuscular mycorrhizal (AM) fungal responses to elevation changes is critical to improve understanding of microbial function in ecosystems under global asymmetrical climate change scenarios. Here we examined AM fungal community in a two-year reciprocal translocation of vegetation-intact soil blocks along a...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep36606
更新日期:2016-11-09 00:00:00
abstract::To examine for a causal relationship between vitamin D and glioma risk we performed an analysis of genetic variants associated with serum 25-hydroxyvitamin D (25(OH)D) levels using Mendelian randomisation (MR), an approach unaffected by biases from confounding. Two-sample MR was undertaken using genome-wide associatio...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-20844-w
更新日期:2018-02-05 00:00:00
abstract::The nanoscale molecular assembly of mammalian viruses during their infectious life cycle remains poorly understood. Their small dimensions, generally bellow the 300nm diffraction limit of light microscopes, has limited most imaging studies to electron microscopy. The recent development of super-resolution (SR) light m...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep29132
更新日期:2016-07-04 00:00:00
abstract::Clostridium difficile infection (CDI) is associated with risk for severe disease and high mortality. Little is known about the extent of hospital-acquired CDI in Mainland China. In this study, we aimed to investigate the annual CDI incidence, bacterial genotypes, risk factors for severe CDI and survival over a 7-year ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-09961-0
更新日期:2017-08-29 00:00:00
abstract::Increasingly, in vivo imaging holds a strategic position in bio-pharmaceutical innovation. We will present the implementation of an integrated multimodal imaging setup enabling the assessment of multiple, complementary parameters. The system allows the fusion of information provided by: Near infrared fluorescent bioma...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-59561-8
更新日期:2020-02-14 00:00:00
abstract::Anoectochilus roxburghii and Anoectochilus formasanus are the major species of genus Anoectochilus used in traditional Chinese medicine for their abundant content of flavonoids and some other medicinal constituents. In recent years, their wild resources are gradually exhausted due to over-collection and ecological det...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-56821-0
更新日期:2019-12-27 00:00:00
abstract::Classification of histologic patterns in lung adenocarcinoma is critical for determining tumor grade and treatment for patients. However, this task is often challenging due to the heterogeneous nature of lung adenocarcinoma and the subjective criteria for evaluation. In this study, we propose a deep learning model tha...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-40041-7
更新日期:2019-03-04 00:00:00
abstract::A variety of post-translational modifications of Plasmodium falciparum proteins, including phosphorylation and ubiquitination, are shown to have key regulatory roles during parasite development. NEDD8 is a ubiquitin-like modifier of cullin-RING E3 ubiquitin ligases, which regulates diverse cellular processes. Although...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-77001-5
更新日期:2020-11-19 00:00:00
abstract::Endonuclease V (EndoV) is a ubiquitous protein present in all three kingdoms of life, responsible for the specific cleavages at the second phosphodiester bond 3' to inosine. E. coli EndoV (EcEndoV) is the first member discovered in the EndoV family. It is a small protein with a compact gene organization, yet with a wi...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep12754
更新日期:2015-08-05 00:00:00
abstract::This study aimed to investigate the dosimetric characteristics of an isocentrically shielded RapidArc (IS-RA) technique for treatment of locally recurrent nasopharyngeal cancer (lrNPC). In IS-RA, the isocenter was placed at the center of the pre-irradiated brainstem (BS)/spinal cord (SC) and the jaws were set to shiel...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep25959
更新日期:2016-05-13 00:00:00
abstract::Concussions carry devastating potential for cognitive, neurologic, and socio-emotional disease, but no objective test reliably identifies a concussion and its severity. A variety of neurological insults compromise sound processing, particularly in complex listening environments that place high demands on brain process...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep39009
更新日期:2016-12-22 00:00:00
abstract::Antimicrobial resistance (AMR) is a major public health threat. Plasmids are able to transfer AMR genes among bacterial isolates. Whole genome sequencing (WGS) is a powerful tool to monitor AMR determinants. However, plasmids are difficult to reconstruct from WGS data. This study aimed to improve the characterization,...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-61158-0
更新日期:2020-03-09 00:00:00
abstract::Belgian Malinois (BM), one of the excellent military dog breeds in South Korea, is usually castrated before sexual maturation. Therefore, the transfer of their genetic features to the next generation is difficult. To overcome this, testicular cells from 4-month-old BMs were frozen. Testicular cells were thawed after 3...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep21919
更新日期:2016-02-24 00:00:00
abstract::Carbon nanotubes (CNTs) are among the most versatile nanomaterials, but their exploitation is hindered by limited dispersibility, especially in aqueous solvents. Here, we show that AP-LYS, a highly cationic soluble derivative of denatured hen egg lysozyme, is a very effective tool for the unbundling and solubilisation...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-52701-9
更新日期:2019-11-12 00:00:00
abstract::Oxidative stress and the formation of plaques which contain amyloid-β (Aβ) peptides are two key hallmarks of Alzheimer's disease (AD). Dityrosine is found in the plaques of AD patients and Aβ dimers have been linked to neurotoxicity. Here we investigate the formation of Aβ dityrosine dimers promoted by Cu2+/+ Fenton r...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-33935-5
更新日期:2018-11-01 00:00:00
abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title:Scientific reports
pub_type: 已发布勘误
doi:10.1038/s41598-019-54834-3
更新日期:2019-12-04 00:00:00
abstract::We evaluated changes in incidence, relative survival (RS), and conditional survival (CS) of head and neck squamous cell carcinoma (HNSCC), focusing on oral tongue squamous cell carcinoma (OTSCC). Data of 74 680 HNSCC patients from 1976 to 2015 were obtained from the Surveillance, Epidemiology, and End Results database...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-64748-0
更新日期:2020-05-12 00:00:00
abstract::Natural history collections are often plagued by missing or inaccurate metadata for collection items, particularly for specimens that are difficult to verify or rare. Avian eggshell in particular can be challenging to identify due to extensive morphological ambiguity among taxa. Species identifications can be improved...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-79852-4
更新日期:2021-01-15 00:00:00
abstract::In this work, an enzymatic biofuel cell (EBC) based on a membraneless and mediatorless glucose enzymatic fuel cell system was constructed for operation in physiological conditions (pH 7.0 and temperature 37 °C). The new platform EBC made of nanocomposite, including magnetic nanoparticles (Fe3O4 NPs) and reduced graphe...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-12417-0
更新日期:2017-10-10 00:00:00
abstract::Drought episodes decrease plant growth and productivity, which in turn cause high economic losses. Plants naturally sense and respond to water stress by activating specific signalling pathways leading to physiological and developmental adaptations. Genetically engineering genes that belong to these pathways might impr...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-44571-y
更新日期:2019-05-30 00:00:00
abstract::Heterodonty is one of the hallmarks of mammals. It has been suggested that, homeobox genes, differentially expressed in the ectomesenchyme of the jaw primordium along the distal-proximal axis, would determine the tooth classes (homeobox code model) based on mouse studies. Because mouse has highly specialized tooth pat...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-49116-x
更新日期:2019-09-06 00:00:00
abstract::The misuse of pharmaceutical opioids is a major public health issue. In Australia, codeine was re-scheduled on 1 February 2018 to restrict access; it is now only available on prescription. The aim of this study was to measure the change in dental opioid prescriptions, one year before and after the codeine re-schedulin...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-65390-6
更新日期:2020-05-21 00:00:00
abstract::Climate can modulate human health at large spatial scales, but the influence of global, regional, and local environments remains poorly understood, especially for neglected diseases, such as mycoses. In this work, we present the correlation between climatic variables and hospitalizations for mycoses in Brazilian state...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-43353-w
更新日期:2019-05-06 00:00:00