Vitrified canine testicular cells allow the formation of spermatogonial stem cells and seminiferous tubules following their xenotransplantation into nude mice.

abstract：:LMNA gene encodes lamins A and C, two major components of the nuclear lamina, a network of intermediate filaments underlying the inner nuclear membrane. Most of LMNA mutations are associated with cardiac and/or skeletal muscles defects. Muscle laminopathies include Emery-Dreifuss Muscular Dystrophy, Limb-Girdle Muscul...

journal_title：Scientific reports

authors： Janin A,Bauer D,Ratti F,Valla C,Bertrand A,Christin E,Chopin E,Streichenberger N,Bonne G,Gache V,Cohen T,Méjat A

更新日期：2018-04-04 00:00:00

abstract：:On an SiO2-patterned c-plane sapphire substrate, GaN domains were grown with their polarity controlled in accordance with the pattern. While N-polar GaN was grown on hexagonally arranged circular openings, Ga-polar GaN was laterally overgrown on mask regions due to polarity inversion occurring at the boundary of the c...

journal_title：Scientific reports

authors： Jang D,Jue M,Kim D,Kim HS,Lee H,Kim C

更新日期：2018-03-07 00:00:00

abstract：:Although the link between sleep disturbances and dopamine (DA)-related neurological and neuropsychiatric disorders is well established, the impact of sleep alterations on neuronal activity of midbrain DA-ergic structures is currently unknown. Here, using wildtype C57Bl mice, we investigated the circadian- and sleep-re...

journal_title：Scientific reports

authors： Fifel K,Meijer JH,Deboer T

更新日期：2018-05-17 00:00:00

abstract：:Outdoor air pollution is a growing public health concern, particularly in urban settings. However, there are limited epidemiological data on outdoor air pollution in rural areas with substantial levels of air pollution attributed to solid fuel burning for household cooking and heating. Xuanwei and Fuyuan are rural cou...

journal_title：Scientific reports

authors： Hu W,Downward G,Wong JYY,Reiss B,Rothman N,Portengen L,Li J,Jones RR,Huang Y,Yang K,Chen Y,Xu J,He J,Bassig B,Seow WJ,Hosgood HD,Zhang L,Wu G,Wei F,Vermeulen R,Lan Q

更新日期：2020-07-09 00:00:00

abstract：:Microbial rhodopsin is a photoreceptor protein found in various bacteria and archaea, and it is considered to be a light-utilization device unique to heterotrophs. Recent studies have shown that several cyanobacterial genomes also include genes that encode rhodopsins, indicating that these auxiliary light-utilizing pr...

journal_title：Scientific reports

authors： Hasegawa M,Hosaka T,Kojima K,Nishimura Y,Nakajima Y,Kimura-Someya T,Shirouzu M,Sudo Y,Yoshizawa S

更新日期：2020-10-07 00:00:00

abstract：:To face the great challenges of ensuring food security and environmental sustainability, agricultural production must be improved by high yield and high resource utilization efficiency (HYHE). We recently addressed this challenge and evaluated yield potential by surveying 735 farmers in 2008-2012 and then conducting 6...

journal_title：Scientific reports

authors： Guo J,Hu X,Gao L,Xie K,Ling N,Shen Q,Hu S,Guo S

更新日期：2017-05-18 00:00:00

abstract：:Solution-based methods represent the most widespread approach used to deposit hybrid organic-inorganic perovskite films for low-cost but efficient solar cells. However, solution-process techniques offer limited control over film morphology and crystallinity, and most importantly do not allow sequential film deposition...

journal_title：Scientific reports

authors： Bonomi S,Marongiu D,Sestu N,Saba M,Patrini M,Bongiovanni G,Malavasi L

更新日期：2018-10-18 00:00:00

abstract：:Knockin (KI) mouse carrying a point mutation has been an invaluable tool for disease modeling and analysis. Genome editing technologies using the CRISPR/Cas system has emerged as an alternative way to create KI mice. However, if the mice carry nucleotide insertions and/or deletions (InDels) in other genes, which could...

journal_title：Scientific reports

authors： Nakajima K,Kazuno AA,Kelsoe J,Nakanishi M,Takumi T,Kato T

更新日期：2016-10-04 00:00:00

abstract：:Histological chorioamnionitis (HCA) is an infection of fetal membranes and complicates 5.2% to 28.5% of all live births. HCA is associated with increased mortality and morbidity in both premature and term neonates. Exposure to HCA may have long-term consequences, including an increased risk for allergic disorders and ...

journal_title：Scientific reports

authors： Gayen Nee' Betal S,Murthy S,Favara M,Fong G,Chan JSY,Addya S,Shaffer TH,Greenspan J,Bhandari V,Rahman I,Aghai ZH

更新日期：2019-04-10 00:00:00

abstract：:This study aimed to determine the role of magnetic resonance imaging (MRI) in diagnosing and describing the characteristics of fistula-in-ano, and the agreement between MRI and operative findings. We conducted a retrospective study in 367 patients with fistula-in-ano who were diagnosed and had an operation at the Univ...

journal_title：Scientific reports

authors： Vo D,Phan C,Nguyen L,Le H,Nguyen T,Pham H

更新日期：2019-11-29 00:00:00

abstract：:It is possible to accurately and economically predict change in protein-protein interaction energy upon mutation (ΔΔG), when a high-resolution structure of the complex is available. This is of growing usefulness for design of high-affinity or otherwise modified binding proteins for therapeutic, diagnostic, industrial,...

journal_title：Scientific reports

authors： Dourado DF,Flores SC

更新日期：2016-05-13 00:00:00

abstract：:The growth kinetics of polymer thin films prepared by plasma-based deposition method were explored using atomic force microscopy. The growth behavior of the first layer of the polythiophene somewhat differs from that of the other layers because the first layer is directly deposited on the substrate, whereas the other ...

journal_title：Scientific reports

authors： Hwang S,Seo H,Jeong DC,Wen L,Han JG,Song C,Kim Y

更新日期：2015-06-18 00:00:00

abstract：:Pyriform sinus fistula (PSF) is a rare congenital entity. We hypothesized that clinical features, diagnosis and treatment may differ between newborns and children. 190 patients diagnosed with PSF were divided into two groups: neonatal (n = 15) and childhood (n = 175). The medical records including demographic and clin...

journal_title：Scientific reports

authors： Sheng Q,Lv Z,Xu W,Liu J

更新日期：2019-12-06 00:00:00

abstract：:The aim was to analyze the effect of fractional flow reserve (FFR), intravascular ultrasound (IVUS) and optical coherence tomography (OCT) on fluoroscopy time (FT), radiation dose (RD) and contrast volume (CV) in patients undergoing coronary angiography. This case-control study included consecutive patients above the ...

journal_title：Scientific reports

authors： De la Garza-Salazar F,Lankenau-Vela DL,Cadena-Nuñez B,González-Cantú A,Romero-Ibarguengoitia ME

更新日期：2020-04-24 00:00:00

abstract：:Endothelial cells (ECs) are major modulators of hemostasis by expressing and releasing pro- and anticoagulant mediators into the circulation. Previous studies showed that cultured ECs release procoagulant mediators into cell culture supernatants as evidenced by the reduction of viscoelastic clotting time. This effect ...

journal_title：Scientific reports

authors： Holnthoner W,Bonstingl C,Hromada C,Muehleder S,Zipperle J,Stojkovic S,Redl H,Wojta J,Schöchl H,Grillari J,Weilner S,Schlimp CJ

更新日期：2017-06-16 00:00:00

abstract：:Traumatic brain injury (TBI) is a risk factor for Alzheimer's disease (AD), although the mechanisms contributing to this increased risk are unknown. Insulin resistance is an additional risk factor for AD whereby decreased insulin signaling increases synaptic sensitivity to amyloid beta (Aβ) and tau. Considering this, ...

journal_title：Scientific reports

authors： Franklin W,Krishnan B,Taglialatela G

更新日期：2019-06-03 00:00:00

abstract：:We previously reported that induction of the adipocyte-specific gene adiponectin (Adipoq) during 3T3-L1 adipocyte differentiation is closely associated with epigenetic memory histone H3 acetylation on the transcribed region of the gene. We used 3T3-L1 adipocytes and Brd4 heterozygous mice to investigate whether the in...

journal_title：Scientific reports

authors： Sakurai N,Inamochi Y,Inoue T,Hariya N,Kawamura M,Yamada M,Dey A,Nishiyama A,Kubota T,Ozato K,Goda T,Mochizuki K

更新日期：2017-09-20 00:00:00

abstract：:The subtle mechanisms by which protein-DNA interactions remain functional across a wide range of temperatures are largely unknown. In this work, we manually curated available information relating fully sequenced archaeal genomes with organism growth temperatures. We built a motif that represents the core promoter of e...

journal_title：Scientific reports

authors： Aptekmann AA,Nadra AD

更新日期：2018-01-22 00:00:00

abstract：:A new simple method is proposed to extract the ambipolar diffusion length for two-dimensional (2D) electronic transport in thin film structures using a scanning photoluminescence microscopy (SPLM) setup. No spatially-resolved photoluminescence detection methods are required. By measuring the excitation-position-depend...

journal_title：Scientific reports

authors： Chu CH,Mao MH,Lin YR,Lin HH

更新日期：2020-03-23 00:00:00

abstract：:Chronic inflammation can be a major driver of the failure of a variety of organs, including chronic kidney disease (CKD). The NLR family pyrin domain-containing 3 (NLRP3) inflammasome has been shown to play a pivotal role in inflammation in a mouse kidney disease model. Nuclear factor erythroid 2-related factor 2 (Nrf...

journal_title：Scientific reports

authors： Sogawa Y,Nagasu H,Iwase S,Ihoriya C,Itano S,Uchida A,Kidokoro K,Taniguchi S,Takahashi M,Satoh M,Sasaki T,Suzuki T,Yamamoto M,Horng T,Kashihara N

更新日期：2017-08-18 00:00:00

abstract：:Theory predicts that social interactions can induce an alignment of behavioral asymmetries between individuals (i.e., population-level lateralization), but evidence for this effect is mixed. To understand how interaction with other individuals affects behavioral asymmetries, we systematically manipulated the social en...

journal_title：Scientific reports

authors： Versace E,Caffini M,Werkhoven Z,de Bivort BL

更新日期：2020-03-11 00:00:00

abstract：:The medicinal leech has established a long-term mutualistic association with Aeromonas veronii, a versatile bacterium which can also display free-living waterborne and fish- or human-pathogenic lifestyles. Here, we investigated the role of antibiotics in the dynamics of interaction between the leech and its gut symbio...

journal_title：Scientific reports

authors： Tasiemski A,Massol F,Cuvillier-Hot V,Boidin-Wichlacz C,Roger E,Rodet F,Fournier I,Thomas F,Salzet M

更新日期：2015-12-04 00:00:00

abstract：:Ecosystem functions are regulated by compositional and functional traits of bacterial communities, shaped by stochastic and deterministic processes. Biogeographical studies have revealed microbial community taxonomy in a given ecosystem to change alongside varying environmental characteristics. Considering that stable...

journal_title：Scientific reports

authors： Booth JM,Fusi M,Marasco R,Mbobo T,Daffonchio D

更新日期：2019-03-06 00:00:00

abstract：:Current image processing methods for dynamic susceptibility contrast (DSC) magnetic resonance imaging (MRI) do not capture complex dynamic information of time-signal intensity curves. We investigated whether an autoencoder-based pattern analysis of DSC MRI captured representative temporal features that improves tissue...

journal_title：Scientific reports

authors： Park JE,Kim HS,Lee J,Cheong EN,Shin I,Ahn SS,Shim WH

更新日期：2020-12-08 00:00:00

abstract：:We describe a novel method to achieve a universal, massive, and fully automated analysis of cell motility behaviours, starting from time-lapse microscopy images. The approach was inspired by the recent successes in application of machine learning for style recognition in paintings and artistic style transfer. The orig...

journal_title：Scientific reports

authors： Mencattini A,Di Giuseppe D,Comes MC,Casti P,Corsi F,Bertani FR,Ghibelli L,Businaro L,Di Natale C,Parrini MC,Martinelli E

更新日期：2020-05-06 00:00:00

abstract：:Chemokines promote leukocyte recruitment during inflammation. The oxidative burst is an important effector mechanism, this leads to the generation of reactive nitrogen species (RNS), including peroxynitrite (ONOO). The current study was performed to determine the potential for nitration to alter the chemical and biolo...

journal_title：Scientific reports

authors： Barker CE,Thompson S,O'Boyle G,Lortat-Jacob H,Sheerin NS,Ali S,Kirby JA

更新日期：2017-03-14 00:00:00

abstract：:The phylogenetic characteristics of microbial communities associated with periodontitis have been well studied, however, little is known about the functional endowments of this ecosystem. The present study examined 73 microbial assemblages from 25 individuals with generalized chronic periodontitis and 25 periodontally...

journal_title：Scientific reports

authors： Dabdoub SM,Ganesan SM,Kumar PS

更新日期：2016-12-19 00:00:00

abstract：:We have recently demonstrated that the rate-limiting enzymes in human glucose metabolism organize into cytoplasmic clusters to form a multienzyme complex, the glucosome, in at least three different sizes. Quantitative high-content imaging data support a hypothesis that the glucosome clusters regulate the direction of ...

journal_title：Scientific reports

authors： Jeon M,Kang HW,An S

更新日期：2018-02-09 00:00:00

abstract：:Renal fibrosis is one of the important pathways involved in end-stage renal failure. Investigating the metabolic changes in the progression of disease may enhance the understanding of its pathogenesis and therapeutic information. In this study, (1)H-nuclear magnetic resonance (NMR)-based metabonomics was firstly used ...

journal_title：Scientific reports

authors： Zhao L,Dong M,Liao S,Du Y,Zhou Q,Zheng H,Chen M,Ji J,Gao H

更新日期：2016-06-03 00:00:00

abstract：:This prospective multicenter randomized comparative cross-over trial aimed at evaluating the influence of hemodialysis vs post-dilution hemodiafiltration with high-flux dialyzers in solute clearance and biocompatibility profile. 32 patients were sequentially dialyzed with Leoceed-21HX, Polypure-22S+, Rexsys-27H and VI...

journal_title：Scientific reports

authors： Morena M,Creput C,Bouzernidj M,Rodriguez A,Chalabi L,Seigneuric B,Lauret C,Bargnoux AS,Dupuy AM,Cristol JP

更新日期：2019-12-04 00:00:00