Modeling and fitting protein-protein complexes to predict change of binding energy.

abstract：:The aim of this study was to investigate the value of multiple parameters retrieved from the FDG PET/CT studies, including SUVmax, SUVmean, SUVpeak, MTV, TLG, tumour size in differentiating retroperitoneal paragangliomas from UCD. 28 patients with solitary retroperitoneal masses who had undergone preoperative 18F-FDG ...

journal_title：Scientific reports

authors： Jiang Y,Hou G,Zhu Z,Huo L,Li F,Cheng W

更新日期：2020-07-30 00:00:00

abstract：:Neonatal animal models are increasingly employed in order to unravel age-specific disease mechanisms. Appropriate tools objectifying the clinical condition of murine neonates are lacking. In this study, we tested a scoring system specifically designed for newborn mice that relies on clinical observation and examinatio...

journal_title：Scientific reports

authors： Fehlhaber B,Heinemann AS,Rübensam K,Willers M,Völlger L,Pfeifer S,von Köckritz-Blickwede M,Viemann D

更新日期：2019-04-11 00:00:00

abstract：:Dioxins are highly toxic to foetuses and prenatal exposure leads to adverse health effects; however, the metabolic pathways involved in dioxin excretion are poorly understood. We determined the dynamics of maternal-to-foetal dioxin transfer during normal pregnancy and how foetuses eliminate polychlorinated dibenzo-p-d...

journal_title：Scientific reports

authors： Morokuma S,Tsukimori K,Hori T,Kato K,Furue M

更新日期：2017-04-07 00:00:00

abstract：:Ferromagnetism can occur in wide-band gap semiconductors as well as in carbon-based materials when specific defects are introduced. It is thus desirable to establish a direct relation between the defects and the resulting ferromagnetism. Here, we contribute to revealing the origin of defect-induced ferromagnetism usin...

journal_title：Scientific reports

authors： Wang Y,Liu Y,Wang G,Anwand W,Jenkins CA,Arenholz E,Munnik F,Gordan OD,Salvan G,Zahn DR,Chen X,Gemming S,Helm M,Zhou S

更新日期：2015-03-11 00:00:00

abstract：:Tau is a microtubule-associated protein whose C-terminal domain consisting of four repeat regions R1, R2, R3 and R4 binds to microtubules to stabilize them. In several neurodegenerative diseases, tau detaches from microtubules to form insoluble aggregates leading to tauopathy. Microtubules are made up of αβ tubulin su...

journal_title：Scientific reports

authors： Bhandare VV,Kumbhar BV,Kunwar A

更新日期：2019-07-25 00:00:00

abstract：:The nucleotides guanosine tetraphosphate and pentaphosphate (together known as (p)ppGpp or magic spot) are produced in plant plastids from GDP/GTP and ATP by RelA-SpoT homologue (RSH) enzymes. In the model plant Arabidopsis (p)ppGpp regulates chloroplast transcription and translation to affect growth, and is also impl...

journal_title：Scientific reports

authors： Avilan L,Puppo C,Villain A,Bouveret E,Menand B,Field B,Gontero B

更新日期：2019-11-27 00:00:00

abstract：:Spiders can cause trophic cascades affecting litter decomposition rates. However, it remains unclear how spiders with different foraging strategies influence faunal communities, or present cascading effects on decomposition. Furthermore, increased dry periods predicted in future climates will likely have important con...

journal_title：Scientific reports

authors： Liu S,Chen J,Gan W,Schaefer D,Gan J,Yang X

更新日期：2015-07-23 00:00:00

abstract：:Appropriate analytical methods are needed for the detection of food authentication. We investigated the applicability of a duplex real-time PCR assay targeting chromosome 1 and two singleplex real-time PCR assays targeting chromosome 9, both published recently, for the qualitative and quantitative determination of wil...

journal_title：Scientific reports

authors： Kaltenbrunner M,Mayer W,Kerkhoff K,Epp R,Rüggeberg H,Hochegger R,Cichna-Markl M

更新日期：2020-10-14 00:00:00

abstract：:Latent class modeling can be used to combine the results of multiple tests to compare the sensitivity and specificity of those tests in the absence of a gold standard. Seroepidemiology for chlamydia infection may be useful for determining the cumulative risk of infection within a population. Initial studies using the ...

journal_title：Scientific reports

authors： Wiegand RE,Cooley G,Goodhew B,Banniettis N,Kohlhoff S,Gwyn S,Martin DL

更新日期：2018-03-09 00:00:00

abstract：:Human pluripotent stem cells (hPSCs) offer tremendous promise in tissue engineering and cell-based therapies due to their unique combination of two properties: pluripotency and unlimited proliferative capacity. However, directed differentiation of hPSCs to clinically relevant cell lineages is needed to achieve the goa...

journal_title：Scientific reports

authors： Randolph LN,Bao X,Zhou C,Lian X

更新日期：2017-05-08 00:00:00

abstract：:In this work, TiN film deposited by plasma enhanced atomic layer deposition (PEALD) is adopted to modify the commercial anatase TiO2 powders. A series of analyses indicate that the surface modification of 20, 50 and 100 cycles of TiN by PEALD does not change the morphology, crystal size, lattice parameters, and surfac...

journal_title：Scientific reports

authors： Cao YQ,Zhao XR,Chen J,Zhang W,Li M,Zhu L,Zhang XJ,Wu D,Li AD

更新日期：2018-08-14 00:00:00

abstract：:Identification of hot spots, a small portion of protein-protein interface residues that contribute the majority of the binding free energy, can provide crucial information for understanding the function of proteins and studying their interactions. Based on our previous method (PredHS), we propose a new computational a...

journal_title：Scientific reports

authors： Wang H,Liu C,Deng L

更新日期：2018-09-24 00:00:00

abstract：:Hallucinogens induce the head-twitch response (HTR), a rapid reciprocal head movement, in mice. Although head twitches are usually identified by direct observation, they can also be assessed using a head-mounted magnet and a magnetometer. Procedures have been developed to automate the analysis of magnetometer recordin...

journal_title：Scientific reports

authors： Halberstadt AL

更新日期：2020-05-20 00:00:00

abstract：:Organic thin-film transistors for high frequency applications require large transconductances in combination with minimal parasitic capacitances. Techniques aiming at eliminating parasitic capacitances are prone to produce a mismatch between electrodes, in particular gaps between the gate and the interlayer electrodes...

journal_title：Scientific reports

authors： Zojer K,Rothländer T,Kraxner J,Schmied R,Palfinger U,Plank H,Grogger W,Haase A,Gold H,Stadlober B

更新日期：2016-09-27 00:00:00

abstract：:We report the experimental observation of extreme instabilities in a self-pulsing fiber laser under the influence of stimulated Brillouin scattering (SBS). Specifically, we observe temporally localized structures with high intensities that can be referred to as rogue events through their statistical behaviour with hig...

journal_title：Scientific reports

authors： Hanzard PH,Talbi M,Mallek D,Kellou A,Leblond H,Sanchez F,Godin T,Hideur A

更新日期：2017-04-04 00:00:00

abstract：:Fibrillar collagen COL6α3 in adipose tissue has been associated with obesity, inflammation, insulin resistance and cancer. We here aimed to identify novel transcriptional regulators of COL6A3 expression. Based on a transcriptome dataset of adipose tissue, we identified strong correlations for 56 genes with COL6A3 mRNA...

journal_title：Scientific reports

authors： Dankel SN,Grytten E,Bjune JI,Nielsen HJ,Dietrich A,Blüher M,Sagen JV,Mellgren G

更新日期：2020-11-19 00:00:00

abstract：:Parathyroid Hormone-Like Hormone (PTHLH) is an autocrine/paracrine ligand that is up-regulated in head and neck squamous cell carcinoma (HNSCC). However, the cellular function and regulatory mechanism in HNSCC remains obscure. We investigated the clinical significance of PTHLH in HNSCC patients, and verified the role ...

journal_title：Scientific reports

authors： Chang WM,Lin YF,Su CY,Peng HY,Chang YC,Hsiao JR,Chen CL,Chang JY,Shieh YS,Hsiao M,Shiah SG

更新日期：2017-01-25 00:00:00

abstract：:Sea surface temperature (SST) is a fundamental driver of tropical weather systems such as monsoon rainfall and tropical cyclones. However, understanding of the factors that control SST variability is lacking, especially during the monsoons when in situ observations are sparse. Here we use a ground-breaking observation...

journal_title：Scientific reports

authors： Vijith V,Vinayachandran PN,Webber BGM,Matthews AJ,George JV,Kannaujia VK,Lotliker AA,Amol P

更新日期：2020-04-27 00:00:00

abstract：:We report on an angle resolved photoemission (ARPES) study of bulk electron-doped perovskite iridate, (Sr(1-x)La(x))3Ir2O7. Fermi surface pockets are observed with a total electron count in keeping with that expected from La substitution. Depending on the energy and polarization of the incident photons, these pockets ...

journal_title：Scientific reports

authors： He J,Hafiz H,Mion TR,Hogan T,Dhital C,Chen X,Lin Q,Hashimoto M,Lu DH,Zhang Y,Markiewicz RS,Bansil A,Wilson SD,He RH

更新日期：2015-02-23 00:00:00

abstract：:Endonuclease V (EndoV) is a ubiquitous protein present in all three kingdoms of life, responsible for the specific cleavages at the second phosphodiester bond 3' to inosine. E. coli EndoV (EcEndoV) is the first member discovered in the EndoV family. It is a small protein with a compact gene organization, yet with a wi...

journal_title：Scientific reports

authors： Zhang Z,Jia Q,Zhou C,Xie W

更新日期：2015-08-05 00:00:00

abstract：:We investigated gender differences in the optic nerve head (ONH) microcirculation status in association with obstructive sleep apnea (OSA) by using laser speckle flowgraphy (LSFG). We evaluated 150 men (60.5 ± 11.0 yrs) and 45 women (63.0 ± 10.6 yrs) who underwent overnight polysomnography. The mean blur rate (MBR), m...

journal_title：Scientific reports

authors： Shiba T,Takahashi M,Matsumoto T,Hori Y

更新日期：2019-12-11 00:00:00

abstract：:Although cochlear venous insufficiency has been considered to cause sudden sensorineural hearing loss (SSHL), there is insufficient clinical evidence to support this hypothesis. We sought to determine whether there is a correlation between draining patterns of the dural venous sinuses and the side of the affected ear ...

journal_title：Scientific reports

authors： Park JW,Kim DH,Kang TK,Sunwoo W

更新日期：2020-04-07 00:00:00

abstract：:Anion exchange membrane fuel cells (AEMFCs) have captivated vast interest due to non-platinum group metal catalysts and fuel flexibility. One of the major shortcomings of AEMFCs, however, is the lack of a stable and high anion conducting membrane. This study introduces a new strategy for fabrication of high conducting...

journal_title：Scientific reports

authors： Das G,Park BJ,Kim J,Kang D,Yoon HH

更新日期：2019-07-02 00:00:00

abstract：:Interleukin-36 (IL-36) represents three cytokines, IL-36α, IL-36β and IL-36γ, which bind to the same receptor, IL-1RL2; however, their physiological function(s) remain poorly understood. Here, the role of IL-36 in immunity against HSV-1 was examined using the flank skin infection mouse model. Expression analyses revea...

journal_title：Scientific reports

authors： Milora KA,Uppalapati SR,Sanmiguel JC,Zou W,Jensen LE

更新日期：2017-07-19 00:00:00

abstract：:It is known that patients with chronic obstructive pulmonary disease experience dyspnea during unsupported arm exercise (UAE). We examined the respiratory variables in during a hair-washing motion for healthy young people requiring the UAE to find the effects across gender, motion, and speed. In this study, 33 healthy...

journal_title：Scientific reports

authors： Takahata M,Ishizawa M,Uchiumi T,Yamaki M,Sato T

更新日期：2020-08-04 00:00:00

abstract：:We have developed sensitive detection of cancer biomarker vascular endothelial growth factor (VEGF) using the p-n heterojunction comprised of p-type BiOI nanoflakes (NFs) array and n-type TiO2 nanotubes (NTs) array. Due to the unique arrayed structure and the synergy effect of photoelectrochemistry in the formed p-n j...

journal_title：Scientific reports

authors： Zhao WW,Liu Z,Shan S,Zhang WW,Wang J,Ma ZY,Xu JJ,Chen HY

更新日期：2014-03-21 00:00:00

abstract：:Prasinophytes are a paraphyletic group of nine lineages of green microalgae that are currently classified either at the class or order level or as clades without formal taxonomic description. Prasinophyte clade VII comprises picoplanktonic algae that are important components of marine phytoplankton communities, partic...

journal_title：Scientific reports

authors： Lopes Dos Santos A,Pollina T,Gourvil P,Corre E,Marie D,Garrido JL,Rodríguez F,Noël MH,Vaulot D,Eikrem W

更新日期：2017-10-25 00:00:00

abstract：:The phylogenetic diversity of marine bacteria belonged to the Bacillus cereus group has not been well investigated. Here, we present the genetic diversity and population structure of 71 bacteria from diverse marine environments, using a multilocus sequence typing (MLST) approach and the analyses of digital DNA-DNA hyb...

journal_title：Scientific reports

authors： Liu Y,Lai Q,Du J,Shao Z

更新日期：2017-04-06 00:00:00

abstract：:Only few applications are currently dealing with personalized adverse drug reactions (ADRs) prediction in case of polypharmacy. The study aimed to develop a patient-tailored ADR web application, considering characteristics from 734 drugs and relevant patient related factors. The application was designed in Python usin...

journal_title：Scientific reports

authors： Valeanu A,Damian C,Marineci CD,Negres S

更新日期：2020-06-12 00:00:00

abstract：:After domestication in the Near East around 10,000 years ago several founder crops, flax included, spread to European latitudes. On reaching northerly latitudes the architecture of domesticated flax became more suitable to fiber production over oil, with longer stems, smaller seeds and fewer axillary branches. Latitud...

journal_title：Scientific reports

authors： Gutaker RM,Zaidem M,Fu YB,Diederichsen A,Smith O,Ware R,Allaby RG

更新日期：2019-01-30 00:00:00